Works by Kjer‐Nielsen, Lars

Results: 27

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.

Published in:

2009

By:

Florence, William C.;
Chengfeng Xia;
Gordy, Laura E.;
Wenlan Chen;
Yalong Zhang;
Scott-Browne, James;
Kinjo, Yuki;
Yu, Karl O. A.;
Keshipeddy, Santosh;
Pellicci, Daniel G.;
Patel, Onisha;
Kjer-Nielsen, Lars;
McCluskey, James;
Godfrey, Dale I.;
Rossjohn, Jamie;
Richardson, Stewart K.;
Porcelli, Steven A.;
Howell, Amy R.;
Hayakawa, Kyoko;
Gapin, Laurent

Publication type:

Correction Notice

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.

Published in:

EMBO Journal, 2009, v. 28, n. 22, p. 3579, doi. 10.1038/emboj.2009.286

By:

Florence, William C.;
Chengfeng Xia;
Gordy, Laura E.;
Wenlan Chen;
Yalong Zhang;
Scott-Browne, James;
Kinjo, Yuki;
Yu, Karl O. A.;
Keshipeddy, Santosh;
Pellicci, Daniel G.;
Patel, Onisha;
Kjer-Nielsen, Lars;
McCluskey, James;
Godfrey, Dale I.;
Rossjohn, Jamie;
Richardson, Stewart K.;
Porcelli, Steven A.;
Howell, Amy R.;
Hayakawa, Kyoko;
Gapin, Laurent

Publication type:

Article

MAIT cells protect against pulmonary Legionella longbeachae infection.

Published in:

Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05202-8

By:

Huimeng Wang;
D'Souza, Criselle;
Xin Yi Lim;
Kostenko, Lyudmila;
Pediongco, Troi J.;
Eckle, Sidonia B. G.;
Meehan, Bronwyn S.;
Mai Shi;
Wang, Nancy;
Shihan Li;
Ligong Liu;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Yoichiro Iwakura;
Gunnersen, Jennifer M.;
Stent, Andrew W.;
Godfrey, Dale I.;
Rossjohn, Jamie;
Westall, Glen P.;
Kjer-Nielsen, Lars

Publication type:

Article

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03321-w

By:

Kok Fei Chan;
Gully, Benjamin S.;
Gras, Stephanie;
Beringer, Dennis X.;
Kjer-Nielsen, Lars;
Cebon, Jonathan;
McCluskey, James;
Weisan Chen;
Rossjohn, Jamie

Publication type:

Article

Identification of a Golgi-localised GRIP domain protein fromArabidopsis thaliana.

Published in:

Planta: An International Journal of Plant Biology, 2004, v. 219, n. 6, p. 1050, doi. 10.1007/s00425-004-1311-9

By:

Gilson, Paul R.;
Vergara, Claudia E.;
Kjer-Nielsen, Lars;
Teasdale, Rohan D.;
Bacic, Antony;
Gleeson, Paul A.

Publication type:

Article

MR1 presents microbial vitamin B metabolites to MAIT cells.

Published in:

Nature, 2012, v. 491, n. 7426, p. 717, doi. 10.1038/nature11605

By:

Kjer-Nielsen, Lars;
Patel, Onisha;
Corbett, Alexandra J.;
Le Nours, Jérôme;
Meehan, Bronwyn;
Liu, Ligong;
Bhati, Mugdha;
Chen, Zhenjun;
Kostenko, Lyudmila;
Reantragoon, Rangsima;
Williamson, Nicholas A.;
Purcell, Anthony W.;
Dudek, Nadine L.;
McConville, Malcolm J.;
O'Hair, Richard A. J.;
Khairallah, George N.;
Godfrey, Dale I.;
Fairlie, David P.;
Rossjohn, Jamie;
McCluskey, James

Publication type:

Article

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire.

Published in:

Nature, 2012, v. 486, n. 7404, p. 554, doi. 10.1038/nature11147

By:

Illing, Patricia T.;
Vivian, Julian P.;
Dudek, Nadine L.;
Kostenko, Lyudmila;
Chen, Zhenjun;
Bharadwaj, Mandvi;
Miles, John J.;
Kjer-Nielsen, Lars;
Gras, Stephanie;
Williamson, Nicholas A.;
Burrows, Scott R.;
Purcell, Anthony W.;
Rossjohn, Jamie;
McCluskey, James

Publication type:

Article

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.

Published in:

Nature, 2010, v. 467, n. 7317, p. 844, doi. 10.1038/nature09448

By:

Siew Siew Pang;
Berry, Richard;
Zhenjun Chen;
Lars Kjer-Nielsen;
Matthew A. Perugini;
King, Glenn F.;
Christina Wang;
Sock Hui Chew;
La Gruta, Nicole L.;
Williams, Neal K.;
Beddoe, Travis;
Tiganis, Tony;
Cowieson, Nathan P.;
Godfrey, Dale I.;
Purcell, Anthony W.;
Wilce, Matthew C. J.;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

Peripheral Blood Mucosal-Associated Invariant T Cells in Tuberculosis Patients and Healthy Mycobacterium tuberculosis-Exposed Controls.

Published in:

2020

By:

Suliman, Sara;
Gela, Anele;
Mendelsohn, Simon C;
Iwany, Sarah K;
Tamara, Kattya Lopez;
Mabwe, Simbarashe;
Bilek, Nicole;
Darboe, Fatoumatta;
Fisher, Michelle;
Corbett, Alexandra J;
Kjer-Nielsen, Lars;
Eckle, Sidonia B G;
Huang, Chuan-Chin;
Zhang, Zibiao;
Lewinsohn, David M;
McCluskey, James;
Rossjohn, Jamie;
Hatherill, Mark;
León, Segundo R;
Calderon, Roger I

Publication type:

journal article

Structural Studies on the αβ T-cell Receptor.

Published in:

IUBMB Life, 2005, v. 57, n. 8, p. 575, doi. 10.1080/15216540500215556

By:

Ely, Lauren K.;
Kjer-Nielsen, Lars;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

T-cell activation by transitory neo-antigens derived from distinct microbial pathways.

Published in:

Nature, 2014, v. 509, n. 7500, p. 361, doi. 10.1038/nature13160

By:

Corbett, Alexandra J.;
Eckle, Sidonia B. G.;
Birkinshaw, Richard W.;
Liu, Ligong;
Patel, Onisha;
Mahony, Jennifer;
Chen, Zhenjun;
Reantragoon, Rangsima;
Meehan, Bronwyn;
Cao, Hanwei;
Williamson, Nicholas A.;
Strugnell, Richard A.;
Van Sinderen, Douwe;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Kjer-Nielsen, Lars;
Rossjohn, Jamie;
McCluskey, James

Publication type:

Article

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection.

Published in:

Science Immunology, 2019, v. 4, n. 41, p. 1, doi. 10.1126/sciimmunol.aaw0402

By:

Huimeng Wang;
Kjer-Nielsen, Lars;
Mai Shi;
D’Souza, Criselle;
Pediongco, Troi J.;
Hanwei Cao;
Kostenko, Lyudmila;
Xin Yi Lim;
Eckle, Sidonia B. G.;
Meehan, Bronwyn S.;
Tianyuan Zhu;
Bingjie Wang;
Zhe Zhao;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Teng, Michele W. L.;
Rossjohn, Jamie;
Di Yu;
de St Groth, Barbara Fazekas;
Lovrecz, George

Publication type:

Article

An overview on the identification of MAIT cell antigens.

Published in:

Immunology & Cell Biology, 2018, v. 96, n. 6, p. 573, doi. 10.1111/imcb.12057

By:

Kjer‐Nielsen, Lars;
Corbett, Alexandra J.;
Chen, Zhenjun;
Liu, Ligong;
Mak, Jeffrey Y. W.;
Godfrey, Dale I.;
Rossjohn, Jamie;
Fairlie, David P.;
McCluskey, James;
Eckle, Sidonia B. G.

Publication type:

Article

Mucosal‐associated invariant T cell receptor recognition of small molecules presented by MR1.

Published in:

Immunology & Cell Biology, 2018, v. 96, n. 6, p. 588, doi. 10.1111/imcb.12017

By:

Awad, Wael;
Le Nours, Jérôme;
Kjer‐Nielsen, Lars;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

The structural bases of direct T-cell allorecognition: implications for T-cell-mediated transplant rejection.

Published in:

Immunology & Cell Biology, 2011, v. 89, n. 3, p. 388, doi. 10.1038/icb.2010.150

By:

Gras, Stephanie;
Kjer-Nielsen, Lars;
Chen, Zhenjun;
Rossjohn, Jamie;
McCluskey, James

Publication type:

Article

Recognition of vitamin B metabolites by mucosal-associated invariant T cells.

Published in:

Nature Communications, 2013, v. 4, n. 7, p. 2142, doi. 10.1038/ncomms3142

By:

Patel, Onisha;
Kjer-Nielsen, Lars;
Le Nours, Jérôme;
Eckle, Sidonia B. G.;
Birkinshaw, Richard;
Beddoe, Travis;
Corbett, Alexandra J.;
Liu, Ligong;
Miles, John J.;
Meehan, Bronwyn;
Reantragoon, Rangsima;
Sandoval-Romero, Maria L.;
Sullivan, Lucy C.;
Brooks, Andrew G.;
Chen, Zhenjun;
Fairlie, David P.;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor.

Published in:

Nature, 2007, v. 448, n. 7149, p. 44, doi. 10.1038/nature05907

By:

Borg, Natalie A.;
Wun, Kwok S.;
Kjer-Nielsen, Lars;
Wilce, Matthew C. J.;
Pellicci, Daniel G.;
Koh, Ruide;
Besra, Gurdyal S.;
Bharadwaj, Mandvi;
Godfrey, Dale I.;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

The GRIP Domain is a Specific Targeting Sequence for a Population of trans-Golgi Network Derived Tubulo-Vesicular Carriers.

Published in:

Traffic, 2001, v. 2, n. 5, p. 336, doi. 10.1034/j.1600-0854.2001.002005336.x

By:

Brown, Darren L.;
Heimann, Kirsten;
Lock, John;
Kjer-Nielsen, Lars;
van Vliet, Catherine;
Stow, Jennifer L.;
Gleeson, Paul A.

Publication type:

Article

Synthetic 5-amino-6-Dribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1109759

By:

Nelson, Adam G.;
Huimeng Wang;
Dewar, Phoebe M.;
Eddy, Eleanor M.;
Songyi Li;
Xin Yi Lim;
Patton, Timothy;
Yuchen Zhou;
Pediongco, Troi J.;
Meehan, Lucy J.;
Meehan, Bronwyn S.;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Stent, Andrew W.;
Kjer-Nielsen, Lars;
McCluskey, James;
Eckle, Sidonia B. G.;
Corbett, Alexandra J.;
Souter, Michael N. T.;
Zhenjun Chen

Publication type:

Article

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex

Published in:

FEBS Letters, 2002, v. 527, n. 1-3, p. 27, doi. 10.1016/S0014-5793(02)03149-6

By:

Macdonald, Whitney;
Williams, David S.;
Clements, Craig S.;
Gorman, Jeffery J.;
Kjer-Nielsen, Lars;
Brooks, Andrew G.;
McCluskey, James;
Rossjohn, Jamie;
Purcell, Anthony W.

Publication type:

Article

A semi-invariant V<sub>?</sub>10<sup>+</sup> T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties.

Published in:

Nature Immunology, 2011, v. 12, n. 7, p. 616, doi. 10.1038/ni.2051

By:

Uldrich, Adam P;
Patel, Onisha;
Cameron, Garth;
Pellicci, Daniel G;
Day, E Bridie;
Sullivan, Lucy C;
Kyparissoudis, Konstantinos;
Kjer-Nielsen, Lars;
Vivian, Julian P;
Cao, Benjamin;
Brooks, Andrew G;
Williams, Spencer J;
Illarionov, Petr;
Besra, Gurdyal S;
Turner, Stephen J;
Porcelli, Steven A;
McCluskey, James;
Smyth, Mark J;
Rossjohn, Jamie;
Godfrey, Dale I

Publication type:

Article

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule.

Published in:

Nature Immunology, 2007, v. 8, n. 3, p. 268, doi. 10.1038/ni1432

By:

Tynan, Fleur E;
Reid, Hugh H;
Kjer-Nielsen, Lars;
Miles, John J;
Wilce, Matthew C J;
Kostenko, Lyudmila;
Borg, Natalie A;
Williamson, Nicholas A;
Beddoe, Travis;
Purcell, Anthony W;
Burrows, Scott R;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

Structural basis for a major histocompatibility complex class Ib–restricted T cell response.

Published in:

Nature Immunology, 2006, v. 7, n. 3, p. 256, doi. 10.1038/ni1312

By:

Hoare, Hilary L.;
Sullivan, Lucy C.;
Pietra, Gabriella;
Clements, Craig S.;
Lee, Eleanor J.;
Ely, Lauren K.;
Beddoe, Travis;
Falco, Michela;
Kjer-Nielsen, Lars;
Reid, Hugh H.;
McCluskey, James;
Moretta, Lorenzo;
Rossjohn, Jamie;
Brooks, Andrew G.

Publication type:

Article

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I–bound peptide.

Published in:

Nature Immunology, 2005, v. 6, n. 11, p. 1114, doi. 10.1038/ni1257

By:

Tynan, Fleur E.;
Burrows, Scott R.;
Buckle, Ashley M.;
Clements, Craig S.;
Borg, Natalie A.;
Miles, John J.;
Beddoe, Travis;
Whisstock, James C.;
Wilce, Matthew C.;
Silins, Sharon L.;
Burrows, Jacqueline M.;
Kjer-Nielsen, Lars;
Kostenko, Lyudmila;
Purcell, Anthony W.;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition.

Published in:

Nature Immunology, 2005, v. 6, n. 2, p. 171, doi. 10.1038/ni1155

By:

Borg, Natalie A;
Ely, Lauren K;
Beddoe, Travis;
Macdonald, Whitney A;
Reid, Hugh H;
Clements, Craig S;
Purcell, Anthony W;
Kjer-Nielsen, Lars;
Miles, John J;
Burrows, Scott R;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

Recipient mucosal-associated invariant T cells control GVHD within the colon.

Published in:

2018

By:

Varelias, Antiopi;
Bunting, Mark D.;
Ormerod, Kate L.;
Koyama, Motoko;
Olver, Stuart D.;
Straube, Jasmin;
Kuns, Rachel D.;
Robb, Renee J.;
Henden, Andrea S.;
Cooper, Leanne;
Lachner, Nancy;
Gartlan, Kate H.;
Lantz, Olivier;
Kjer-Nielsen, Lars;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Clouston, Andrew D.;
McCluskey, James;
Rossjohn, Jamie;
Lane, Steven W.

Publication type:

journal article

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 4, p. 1752, doi. 10.1172/JCI78941

By:

Magalhaes, Isabelle;
Pingris, Karine;
Poitou, Christine;
Bessoles, Stéphanie;
Venteclef, Nicolas;
Kiaf, Badr;
Beaudoin, Lucie;
Da Silva, Jennifer;
Allatif, Omran;
Rossjohn, Jamie;
Kjer-Nielsen, Lars;
McCluskey, James;
Ledoux, Séverine;
Genser, Laurent;
Torcivia, Adriana;
Soudais, Claire;
Lantz, Olivier;
Boitard, Christian;
Aron-Wisnewsky, Judith;
Larger, Etienne

Publication type:

Article