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Inhibition of the Phospholipase Cε–c-Jun N-Terminal Kinase Axis Suppresses Glioma Stem Cell Properties.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8785, doi. 10.3390/ijms23158785
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- Article
HDAC Class I Inhibitor Domatinostat Preferentially Targets Glioma Stem Cells over Their Differentiated Progeny.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8084, doi. 10.3390/ijms23158084
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- Article
Targeting Folate Metabolism Is Selectively Cytotoxic to Glioma Stem Cells and Effectively Cooperates with Differentiation Therapy to Eliminate Tumor-Initiating Cells in Glioma Xenografts.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11633, doi. 10.3390/ijms222111633
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- Article
Serum prolactin levels and prolactin m RNA expression in peripheral blood mononuclear cells in hepatitis C virus infection.
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- Journal of Medical Virology, 2013, v. 85, n. 7, p. 1199, doi. 10.1002/jmv.23599
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- Article
Dexamethasone Sensitizes Cancer Stem Cells to Gemcitabine and 5-Fluorouracil by Increasing Reactive Oxygen Species Production through NRF2 Reduction.
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- Life (2075-1729), 2021, v. 11, n. 9, p. 885, doi. 10.3390/life11090885
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- Article
New developments in medical education for the realization of next-generation personalized medicine: concept and design of a medical education and training program through the genomic cohort study.
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- Journal of Human Genetics, 2013, v. 58, n. 9, p. 639, doi. 10.1038/jhg.2013.69
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- Article
Increased expression of Schwannoma-derived growth factor (SDGF) mRNA in rat tumor cells: Involvement of SDGF in the growth promotion of rat gliomas.
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- International Journal of Cancer, 1996, v. 66, n. 3, p. 352, doi. 10.1002/(SICI)1097-0215(19960503)66:3<352::AID-IJC15>3.0.CO;2-D
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- Article
MEK-ERK Signaling Dictates DNA-Repair Gene MGMT Expression and Temozolomide Resistance of Stem-Like Glioblastoma Cells via the MDM2-p53 Axis.
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- Stem Cells, 2011, v. 29, n. 12, p. 1942, doi. 10.1002/stem.753
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- Article
FoxO3a Functions as a Key Integrator of Cellular Signals That Control Glioblastoma Stem-like Cell Differentiation and Tumorigenicity.
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- Stem Cells, 2011, v. 29, n. 9, p. 1327, doi. 10.1002/stem.696
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- Publication type:
- Article
Crosstalk Between the PI3K/mTOR and MEK/ERK Pathways Involved in the Maintenance of Self-Renewal and Tumorigenicity of Glioblastoma Stem-Like Cells.
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- Stem Cells, 2010, v. 28, n. 11, p. 1930, doi. 10.1002/stem.521
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- Publication type:
- Article
The Real-World status and risk factors for a poor prognosis in elderly patients with primary central nervous system malignant lymphomas: a multicenter, retrospective cohort study of the Tohoku Brain Tumor Study Group.
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- International Journal of Clinical Oncology, 2022, v. 27, n. 1, p. 77, doi. 10.1007/s10147-021-02042-3
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- Article
Critical Role for Mitochondrial Oxidative Phosphorylation in the Activation of Tumor Suppressors Bax and Bak.
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- JNCI: Journal of the National Cancer Institute, 2006, v. 98, n. 20, p. 1462, doi. 10.1093/jnci/djj395
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- Article
Increased Ras expression and caspase-independent neuroblastoma cell death: possible mechanism of spontaneous neuroblastoma regression.
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- 2002
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- Publication type:
- journal article
CEP-1347 Dually Targets MDM4 and PKC to Activate p53 and Inhibit the Growth of Uveal Melanoma Cells.
- Published in:
- Cancers, 2024, v. 16, n. 1, p. 118, doi. 10.3390/cancers16010118
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- Publication type:
- Article
Antagonizing MDM2 Overexpression Induced by MDM4 Inhibitor CEP-1347 Effectively Reactivates Wild-Type p53 in Malignant Brain Tumor Cells.
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- Cancers, 2023, v. 15, n. 17, p. 4326, doi. 10.3390/cancers15174326
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- Publication type:
- Article
Metformin with Temozolomide for Newly Diagnosed Glioblastoma: Results of Phase I Study and a Brief Review of Relevant Studies.
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- Cancers, 2022, v. 14, n. 17, p. 4222, doi. 10.3390/cancers14174222
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- Publication type:
- Article
Gemcitabine Cooperates with Everolimus to Inhibit the Growth of and Sensitize Malignant Meningioma Cells to Apoptosis Induced by Navitoclax, an Inhibitor of Anti-Apoptotic BCL-2 Family Proteins.
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- Cancers, 2022, v. 14, n. 7, p. 1706, doi. 10.3390/cancers14071706
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- Publication type:
- Article
Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs.
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- Cancers, 2019, v. 11, n. 10, p. 1550, doi. 10.3390/cancers11101550
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- Article
Brexpiprazole, a Serotonin-Dopamine Activity Modulator, Can Sensitize Glioma Stem Cells to Osimertinib, a Third-Generation EGFR-TKI, via Survivin Reduction.
- Published in:
- Cancers, 2019, v. 11, n. 7, p. 947, doi. 10.3390/cancers11070947
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- Article
Verteporfin inhibits oxidative phosphorylation and induces cell death specifically in glioma stem cells.
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- FEBS Journal, 2020, v. 287, n. 10, p. 2023, doi. 10.1111/febs.15187
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- Publication type:
- Article
Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells.
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- Oncogene, 1999, v. 18, n. 13, p. 2281, doi. 10.1038/sj.onc.1202538
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- Publication type:
- Article
Caspase-dependent apoptosis of COS-7 cells induced by Bax overexpression: differential effects of Bcl-2 and Bcl-x<sub>L</sub> on Bax-induced caspase activation and apoptosis.
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- Oncogene, 1997, v. 15, n. 15, p. 1763, doi. 10.1038/sj.onc.1201349
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- Publication type:
- Article
Pim-1 kinase stimulates c-Myc-mediated death signaling upstream of caspase-3 (CPP32)-like protease activation.
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- Oncogene, 1997, v. 15, n. 12, p. 1471, doi. 10.1038/sj.onc.1201326
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- Publication type:
- Article
Roles for hENT1 and dCK in gemcitabine sensitivity and malignancy of meningioma.
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- Neuro-Oncology, 2021, v. 23, n. 6, p. 945, doi. 10.1093/neuonc/noab015
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- Publication type:
- Article
Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells.
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- Neuro-Oncology, 2010, v. 12, n. 12, p. 1205, doi. 10.1093/neuonc/noq103
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- Publication type:
- Article
Heparin-binding epidermal growth factor-like growth factor stimulates mitogenic signaling and is highly expressed in human malignant gliomas.
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- Acta Neuropathologica, 1998, v. 96, n. 4, p. 322, doi. 10.1007/s004010050901
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- Publication type:
- Article
Caspase-independent programmed cell death with necrotic morphology.
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- Cell Death & Differentiation, 1999, v. 6, n. 6, p. 508, doi. 10.1038/sj.cdd.4400526
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- Publication type:
- Article
The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo.
- Published in:
- Biomedicines, 2023, v. 11, n. 7, p. 1967, doi. 10.3390/biomedicines11071967
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- Publication type:
- Article
Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing.
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- Biomedicines, 2020, v. 8, n. 8, p. 273, doi. 10.3390/biomedicines8080273
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- Publication type:
- Article
Association of stem cell marker CD133 expression with dissemination of glioblastomas.
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- Neurosurgical Review, 2010, v. 33, n. 2, p. 175, doi. 10.1007/s10143-010-0239-8
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- Article
Treatment outcomes in glioblastoma patients aged 76 years or older: a multicenter retrospective cohort study.
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- Journal of Neuro-Oncology, 2014, v. 116, n. 2, p. 299, doi. 10.1007/s11060-013-1291-3
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- Publication type:
- Article
Licochalcone A specifically induces cell death in glioma stem cells via mitochondrial dysfunction.
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- FEBS Open Bio, 2017, v. 7, n. 6, p. 835, doi. 10.1002/2211-5463.12226
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- Article
Inhibition of the Lipid Droplet–Peroxisome Proliferator-Activated Receptor α Axis Suppresses Cancer Stem Cell Properties.
- Published in:
- Genes, 2021, v. 12, n. 1, p. 99, doi. 10.3390/genes12010099
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- Publication type:
- Article
CEP-1347 Boosts Chk2-Mediated p53 Activation by Ionizing Radiation to Inhibit the Growth of Malignant Brain Tumor Cells.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 17, p. 9473, doi. 10.3390/ijms25179473
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- Article
The MDM2–p53 Axis Represents a Therapeutic Vulnerability Unique to Glioma Stem Cells.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 3948, doi. 10.3390/ijms25073948
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- Article
Domatinostat Targets the FOXM1–Survivin Axis to Reduce the Viability of Ovarian Cancer Cells Alone and in Combination with Chemotherapeutic Agents.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10817, doi. 10.3390/ijms241310817
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- Publication type:
- Article
Time-staggered inhibition of JNK effectively sensitizes chemoresistant ovarian cancer cells to cisplatin and paclitaxel.
- Published in:
- Oncology Reports, 2016, v. 35, n. 1, p. 593, doi. 10.3892/or.2015.4377
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- Article