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Multistage carcinogenesis involves multiple genes and multiple mechanisms.
Published in:
Journal of Cellular Physiology, 1984, v. 121, p. 127, doi. 10.1002/jcp.1041210416
By:
- Weinstein, I. Bernard;
- Gattoni-Celli, Sebastiano;
- Kirschmeier, Paul;
- Lambert, Michael;
- Hsiao, Wendy;
- Backer, Joseph;
- Jeffrey, Alan
Publication type:
Article
Differential expression of genes in human normal and breast cancer cells determined by microarray technique.
Published in:
1999
By:
- Liu, Suxing;
- Wu, Qun;
- Kirschmeier, Paul;
- McClanahan, Terri;
- Greene, Johnathan;
- Hernandez, Marco;
- Wang, Luquan
Publication type:
Abstract
Preclinical and clinical evaluation of farnesyltransferase inhibitors.
Published in:
Current Oncology Reports, 2003, v. 5, n. 2, p. 99, doi. 10.1007/s11912-003-0096-5
By:
- Baum, Charles;
- Kirschmeier, Paul
Publication type:
Article
Unraveling the clinicopathological features driving the emergence of ESR1 mutations in metastatic breast cancer.
Published in:
NPJ Breast Cancer, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41523-018-0075-5
By:
- Kuang, Yanan;
- Siddiqui, Bilal;
- Hu, Jiani;
- Pun, Matthew;
- Cornwell, MacIntosh;
- Buchwalter, Gilles;
- Hughes, Melissa E.;
- Wagle, Nikhil;
- Kirschmeier, Paul;
- Jänne, Pasi A.;
- Paweletz, Cloud P.;
- Lin, Nancy U.;
- Krop, Ian E.;
- Barry, William T.;
- Winer, Eric P.;
- Brown, Myles;
- Jeselsohn, Rinath
Publication type:
Article
Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression.
Published in:
Oncogene, 2003, v. 22, n. 23, p. 3645, doi. 10.1038/sj.onc.1206477
By:
- Mirza, Asra;
- Wu, Qun;
- Wang, Luquan;
- McClanahan, Terri;
- Bishop, W Robert;
- Gheyas, Ferdous;
- Ding, Wei;
- Hutchins, Beth;
- Hockenberry, Tish;
- Kirschmeier, Paul;
- Greene, Jonathan R;
- Liu, Suxing
Publication type:
Article
Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway.
Published in:
Oncogene, 2002, v. 21, n. 17, p. 2613, doi. 10.1038/sj.onc.1205353
By:
- Mirza, Asra;
- McGuirk, Marnie;
- Hockenberry, Tish N.;
- Qun Wu;
- Ashar, Hena;
- Black, Stuart;
- Shu Fen Wen;
- Luquan Wang;
- Kirschmeier, Paul;
- Bishop, W. Robert;
- Nielsen, Loretta L.;
- Pickett, Cecil B.;
- Suxing Liu
Publication type:
Article
Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations.
Published in:
Molecular Oncology, 2021, v. 15, n. 1, p. 27, doi. 10.1002/1878-0261.12673
By:
- Ogino, Atsuko;
- Choi, Jihyun;
- Lin, Mika;
- Wilkens, Margaret K.;
- Calles, Antonio;
- Xu, Man;
- Adeni, Anika E.;
- Chambers, Emily S.;
- Capelletti, Marzia;
- Butaney, Mohit;
- Gray, Nathanael S.;
- Gokhale, Prafulla C.;
- Palakurthi, Sangeetha;
- Kirschmeier, Paul;
- Oxnard, Geoffrey R.;
- Sholl, Lynette M.;
- Jänne, Pasi A.
Publication type:
Article
IMMU-19. PD-1 BLOCKADE ACTIVATES CD4 T CELLS AND THE INNATE IMMUNE RESPONSE FOR GLIOBLASTOMA ERADICATION.
Published in:
Neuro-Oncology, 2018, v. 20, p. vi125, doi. 10.1093/neuonc/noy148.522
By:
- Speranza, Maria Carmela;
- Klein, Sarah R;
- Gokhale, Prafulla C;
- Wilkens, Margaret K;
- Jones, Kristen L;
- Chaudhri, Apoorvi;
- Kirschmeier, Paul T;
- Reardon, David;
- Freeman, Gordon
Publication type:
Article
Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade.
Published in:
2021
By:
- Sehgal, Kartik;
- Portell, Andrew;
- Ivanova, Elena V.;
- Lizotte, Patrick H.;
- Mahadevan, Navin R.;
- Greene, Jonathan R.;
- Vajdi, Amir;
- Gurjao, Carino;
- Teceno, Tyler;
- Taus, Luke J.;
- Thai, Tran C.;
- Shunsuke Kitajima;
- Liu, Derek;
- Tetsuo Tani;
- Noureddine, Moataz;
- Lau, Christie J.;
- Kirschmeier, Paul T.;
- Liu, David;
- Giannakis, Marios;
- Jenkins, Russell W.
Publication type:
journal article
Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C.
Published in:
2017
By:
- Kedves, Alexia T.;
- Gleim, Scott;
- Xiaoyou Liang;
- Sigoillot, Frederic;
- Harbinski, Fred;
- Benander, Christina;
- George, Elizabeth;
- Jenkins, Jeremy;
- Forrester, William C.;
- Bonal, Dennis M.;
- Gokhale, Prafulla C.;
- Nguyen, Quang-De;
- Kirschmeier, Paul T.;
- Distel, Robert J.;
- Goldberg, Michael S.;
- Sanghavi, Sneha;
- Liang, Xiaoyou
Publication type:
journal article
Phase 1 safety, pharmacokinetic and pharmacodynamic study of the cyclin-dependent kinase inhibitor dinaciclib administered every three weeks in patients with advanced malignancies.
Published in:
2017
By:
- Mita, Monica M;
- Mita, Alain C;
- Moseley, Jennifer L;
- Poon, Jennifer;
- Small, Karen A;
- Jou, Ying-Ming;
- Kirschmeier, Paul;
- Zhang, Da;
- Zhu, Yali;
- Statkevich, Paul;
- Sankhala, Kamelesh K;
- Sarantopoulos, John;
- Cleary, James M;
- Chirieac, Lucian R;
- Rodig, Scott J;
- Bannerji, Rajat;
- Shapiro, Geoffrey I
Publication type:
journal article
SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 4, p. 923, doi. 10.1007/s00280-011-1568-1
By:
- Basso, Andrea;
- Liu, Ming;
- Gray, Kimberly;
- Tevar, Seema;
- Lee, Suining;
- Liang, Lianzhu;
- Ponery, Abdul;
- Smith, Elizabeth;
- Monsma, Frederick;
- Yu, Tao;
- Zhang, Yonglian;
- Kerekes, Angela;
- Esposite, Sara;
- Xiao, Yushi;
- Tagat, Jayaram;
- Hicklin, Daniel;
- Kirschmeier, Paul
Publication type:
Article
Continuous and intermittent dosing of lonafarnib potentiates the therapeutic efficacy of docetaxel on preclinical human prostate cancer models.
Published in:
International Journal of Cancer, 2009, v. 125, n. 11, p. 2711, doi. 10.1002/ijc.24644
By:
- Liu, Gongjie;
- Taylor, Stacey A.;
- Marrinan, Cindy H.;
- Hsieh, Yunsheng;
- Bishop, W. Robert;
- Kirschmeier, Paul;
- Long, Brian J.
Publication type:
Article
A first-in-human, phase 1, dose-escalation study of dinaciclib, a novel cyclin-dependent kinase inhibitor, administered weekly in subjects with advanced malignancies.
Published in:
Journal of Translational Medicine, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1479-5876-11-259
By:
- Nemunaitis, John J.;
- Small, Karen A.;
- Kirschmeier, Paul;
- Da Zhang;
- Yali Zhu;
- Ying-Ming Jou;
- Statkevich, Paul;
- Siu-Long Yao;
- Bannerji, Rajat
Publication type:
Article
A first-in-human, phase 1, dose-escalation study of dinaciclib, a novel cyclin-dependent kinase inhibitor, administered weekly in subjects with advanced malignancies.
Published in:
2013
By:
- Nemunaitis, John J;
- Small, Karen A;
- Kirschmeier, Paul;
- Zhang, Da;
- Zhu, Yali;
- Jou, Ying-Ming;
- Statkevich, Paul;
- Yao, Siu-Long;
- Bannerji, Rajat
Publication type:
journal article

Found: 15