Works by Kimura, Nobuyuki

Results: 42

Microwave properties of the system for TiO 2 sandwiched by Bi-based oxide superconductor.

Published in:

Ferroelectrics, 2001, v. 257, n. 1, p. 129, doi. 10.1080/00150190108016291

By:

Sugihara, Sunao;
Yutoh, Yukio;
Kimura, Nobuyuki

Publication type:

Article

Molecular dissection of ALS‐linked TDP‐43 – involvement of the Gly‐rich domain in interaction with G‐quadruplex mRNA.

Published in:

FEBS Letters, 2020, v. 594, n. 14, p. 2254, doi. 10.1002/1873-3468.13800

By:

Ishiguro, Akira;
Kimura, Nobuyuki;
Noma, Takashi;
Shimo‐Kon, Rieko;
Ishihama, Akira;
Kon, Takahide

Publication type:

Article

A potential function for neuronal exosomes: Sequestering intracerebral amyloid-β peptide.

Published in:

FEBS Letters, 2015, v. 589, n. 1, p. 84, doi. 10.1016/j.febslet.2014.11.027

By:

Yuyama, Kohei;
Sun, Hui;
Usuki, Seigo;
Sakai, Shota;
Hanamatsu, Hisatoshi;
Mioka, Tetsuo;
Kimura, Nobuyuki;
Okada, Megumi;
Tahara, Hidetoshi;
Furukawa, Jun-ichi;
Fujitani, Naoki;
Shinohara, Yasuro;
Igarashi, Yasuyuki

Publication type:

Article

A Seed for Alzheimer Amyloid in the Brain.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 20, p. 4894, doi. 10.1523/JNEUROSCI.0861-04.2004

By:

Hayashi, Hideki;
Kimura, Nobuyuki;
Yamaguchi, Haruyasu;
Hasegawa, Kazuhiro;
Yokoseki, Tatsuki;
Shibata, Masao;
Yamamoto, Naoki;
Michikawa, Makoto;
Yoshikawa, Yasuhiro;
Terao, Keiji;
Matsuzaki, Katsumi;
Lemere, Cynthia A.;
Selkoe, Dennis J.;
Naiki, Hironobu;
Yanagisawa, Katsuhiko

Publication type:

Article

Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2012, v. 7, n. 1, p. 50, doi. 10.1186/1750-1326-7-50

By:

Yuhki Saito;
Tsuyoshi Inoue;
Gang Zhu;
Naoki Kimura;
Motohiro Okada;
Masaki Nishimura;
Nobuyuki Kimura;
Shigeo Murayama;
Sunao Kaneko;
Ryuichi Shigemoto;
Keiji Imoto;
Toshiharu Suzuki

Publication type:

Article

Diabetes Mellitus Induces Alzheimer's Disease Pathology: Histopathological Evidence from Animal Models.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 4, p. 503, doi. 10.3390/ijms17040503

By:

Nobuyuki Kimura

Publication type:

Article

Tau pathology in aged cynomolgus monkeys is progressive supranuclear palsy/corticobasal degeneration--but not Alzheimer disease-like -Ultrastructural mapping of tau by EDX-.

Published in:

Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0385-5

By:

Toshiki Uchihara;
Kentaro Endo;
Hiromi Kondo;
Sachi Okabayashi;
Nobuhiro Shimozawa;
Yasuhiro Yasutomi;
Eijiro Adachi;
Nobuyuki Kimura

Publication type:

Article

Sendai virus vector-mediated brain-derived neurotrophic factor expression ameliorates memory deficits and synaptic degeneration in a transgenic mouse model of Alzheimer's disease.

Published in:

Journal of Neuroscience Research, 2012, v. 90, n. 5, p. 981, doi. 10.1002/jnr.22830

By:

Iwasaki, Yuki;
Negishi, Takayuki;
Inoue, Makoto;
Tashiro, Tomoko;
Tabira, Takeshi;
Kimura, Nobuyuki

Publication type:

Article

Presenilin-2 in the cynomolgus monkey brain: investigation of age-related changes.

Published in:

Primates, 2004, v. 45, n. 3, p. 167, doi. 10.1007/s10329-004-0076-x

By:

Kimura, Nobuyuki;
Nakamura, Shin' ichiro;
Ono, Fumiko;
Sakakibara, Ippei;
Ishii, Yoshiyuki;
Kyuwa, Shigeru;
Yoshikawa, Yasuhiro

Publication type:

Article

Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD.

Published in:

Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01729-8

By:

Ueda, Tetsuhiro;
Takeuchi, Toshihide;
Fujikake, Nobuhiro;
Suzuki, Mari;
Minakawa, Eiko N.;
Ueyama, Morio;
Fujino, Yuzo;
Kimura, Nobuyuki;
Nagano, Seiichi;
Yokoseki, Akio;
Onodera, Osamu;
Mochizuki, Hideki;
Mizuno, Toshiki;
Wada, Keiji;
Nagai, Yoshitaka

Publication type:

Article

Age-related alterations in protein phosphatase 2A methylation levels in brains of cynomolgus monkeys: a pilot study.

Published in:

Journal of Biochemistry, 2023, v. 17, n. 6, p. 435, doi. 10.1093/jb/mvad006

By:

Ando, Sana;
Sakurai, Masashi;
Shibutani, Shusaku;
Kimura, Nobuyuki;
Shimozawa, Nobuhiro;
Yasutomi, Yasuhiro;
Yabe, Ryotaro;
Ohama, Takashi;
Sato, Koichi

Publication type:

Article

Retromer and Rab2-dependent trafficking mediate PS1 degradation by proteasomes in endocytic disturbance.

Published in:

Journal of Neurochemistry, 2016, v. 137, n. 4, p. 647, doi. 10.1111/jnc.13586

By:

Ueda, Naoya;
Tomita, Taisuke;
Yanagisawa, Katsuhiko;
Kimura, Nobuyuki

Publication type:

Article

Correction to: Phase II study of sunitinib in Japanese patients with unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumor.

Published in:

2019

By:

Ito, Tetsuhide;
Okusaka, Takuji;
Nishida, Toshirou;
Yamao, Kenji;
Igarashi, Hisato;
Morizane, Chigusa;
Kondo, Shunsuke;
Mizuno, Nobumasa;
Hara, Kazuo;
Sawaki, Akira;
Hashigaki, Satoshi;
Kimura, Nobuyuki;
Murakami, Mami;
Ohki, Emiko;
Chao, Richard C.;
Imamura, Masayuki

Publication type:

Correction Notice

Phase I study of sunitinib plus S-1 and cisplatin in Japanese patients with advanced or metastatic gastric cancer.

Published in:

Investigational New Drugs, 2014, v. 32, n. 2, p. 261, doi. 10.1007/s10637-013-9948-5

By:

Boku, Narikazu;
Muro, Kei;
Machida, Nozomu;
Hashigaki, Satoshi;
Kimura, Nobuyuki;
Suzuki, Mie;
Lechuga, Mariajose;
Miyata, Yoshinori

Publication type:

Article

Phase II study of sunitinib in Japanese patients with unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumor.

Published in:

Investigational New Drugs, 2013, v. 31, n. 5, p. 1265, doi. 10.1007/s10637-012-9910-y

By:

Ito, Tetsuhide;
Okusaka, Takuji;
Nishida, Toshirou;
Yamao, Kenji;
Igarashi, Hisato;
Morizane, Chigusa;
Kondo, Shunsuke;
Mizuno, Nobumasa;
Hara, Kazuo;
Sawaki, Akira;
Hashigaki, Satoshi;
Kimura, Nobuyuki;
Murakami, Mami;
Ohki, Emiko;
Chao, Richard;
Imamura, Masayuki

Publication type:

Article

Feasibility study of two schedules of sunitinib in combination with pemetrexed in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2012, v. 30, n. 2, p. 639, doi. 10.1007/s10637-010-9565-5

By:

Okamoto, Isamu;
Shimizu, Toshio;
Miyazaki, Masaki;
Tsurutani, Junji;
Ichikawa, Yasuko;
Terashima, Masaki;
Takeda, Masayuki;
Fumita, Soichi;
Ohki, Emiko;
Kimura, Nobuyuki;
Hashimoto, Junichi;
Nakagawa, Kazuhiko

Publication type:

Article

Efficacy and safety of sunitinib in Japanese patients with progressive, advanced/metastatic, well-differentiated, unresectable pancreatic neuroendocrine tumors: final analyses from a Phase II study.

Published in:

Japanese Journal of Clinical Oncology, 2019, v. 49, n. 4, p. 354, doi. 10.1093/jjco/hyz009

By:

Ito, Tetsuhide;
Tori, Masayuki;
Hashigaki, Satoshi;
Kimura, Nobuyuki;
Sato, Kazuo;
Ohki, Emiko;
Sawaki, Akira;
Okusaka, Takuji

Publication type:

Article

Immunohistochemical and Biochemical Analyses of LGI3 in Monkey Brain: LGI3 Accumulates in Aged Monkey Brains.

Published in:

Cellular & Molecular Neurobiology, 2007, v. 27, n. 6, p. 819, doi. 10.1007/s10571-007-9205-6

By:

Sachi Okabayashi;
Nobuyuki Kimura

Publication type:

Article

Aβ Upregulates and Colocalizes with LGI3 in Cultured Rat Astrocytes.

Published in:

Cellular & Molecular Neurobiology, 2007, v. 27, n. 3, p. 335, doi. 10.1007/s10571-006-9127-8

By:

Nobuyuki Kimura;
Yoshiyuki Ishii;
Shingo Suzaki;
Takayuki Negishi;
Shigeru Kyuwa;
Yasuhiro Yoshikawa

Publication type:

Article

Non-human primate model of amyotrophic lateral sclerosis with cytoplasmic mislocalization of TDP-43.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 3, p. 833, doi. 10.1093/brain/awr348

By:

Uchida, Azusa;
Sasaguri, Hiroki;
Kimura, Nobuyuki;
Tajiri, Mio;
Ohkubo, Takuya;
Ono, Fumiko;
Sakaue, Fumika;
Kanai, Kazuaki;
Hirai, Takashi;
Sano, Tatsuhiko;
Shibuya, Kazumoto;
Kobayashi, Masaki;
Yamamoto, Mariko;
Yokota, Shigefumi;
Kubodera, Takayuki;
Tomori, Masaki;
Sakaki, Kyohei;
Enomoto, Mitsuhiro;
Hirai, Yukihiko;
Kumagai, Jiro

Publication type:

Article

Age-related modulation of γ-secretase activity in non-human primate brains.

Published in:

Journal of Neurochemistry, 2012, v. 123, n. 1, p. 21, doi. 10.1111/j.1471-4159.2012.07884.x

By:

Nishimura, Masaki;
Nakamura, Shin-ichiro;
Kimura, Nobuyuki;
Liu, Lei;
Suzuki, Toshiharu;
Tooyama, Ikuo

Publication type:

Article

TDP-43 binds and transports G-quadruplex-containing m RNAs into neurites for local translation.

Published in:

Genes to Cells, 2016, v. 21, n. 5, p. 466, doi. 10.1111/gtc.12352

By:

Ishiguro, Akira;
Kimura, Nobuyuki;
Watanabe, Yuto;
Watanabe, Sumiko;
Ishihama, Akira

Publication type:

Article

Diabetes Mellitus Accelerates Aβ Pathology in Brain Accompanied by Enhanced GAβ Generation in Nonhuman Primates.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0117362

By:

Okabayashi, Sachi;
Shimozawa, Nobuhiro;
Yasutomi, Yasuhiro;
Yanagisawa, Katsuhiko;
Kimura, Nobuyuki

Publication type:

Article

Glasdegib with intensive/nonintensive chemotherapy in Japanese patients with untreated acute myeloid leukemia or high‐risk myelodysplastic syndromes.

Published in:

Cancer Science, 2024, v. 115, n. 4, p. 1250, doi. 10.1111/cas.16054

By:

Izutsu, Koji;
Ubukawa, Kumi;
Morishita, Takanobu;
Onishi, Yasushi;
Ishizawa, Kenichi;
Fujii, Yosuke;
Kimura, Nobuyuki;
Yokochi, Miyuu;
Naoe, Tomoki

Publication type:

Article

Monitoring of retrohepatic inferior vena caval pressure predicted postoperative hematoma after hepatic surgery.

Published in:

2001

By:

Kawase, Masaki;
Kimura, Nobuyuki;
Kimura, Tomomasa;
Shimada, Yasuhiro

Publication type:

Letter

EXPERIMENTAL STUDY ON FLOW OPTIMIZATION IN UPPER PLENUM OF REACTOR VESSEL FOR A COMPACT SODIUM-COOLED FAST REACTOR.

Published in:

Nuclear Technology, 2005, v. 152, n. 2, p. 210, doi. 10.13182/NT05-A3671

By:

Kimura, Nobuyuki;
Hayashi, Kenji;
Kamide, Hideki;
Itoh, Masami;
Sekine, Tadashi

Publication type:

Article

Decrease in p3‐Alcβ37 and p3‐Alcβ40, products of Alcadein β generated by γ‐secretase cleavages, in aged monkeys and patients with Alzheimer's disease.

Published in:

Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2019, v. 5, n. 1, p. 740, doi. 10.1016/j.trci.2019.09.015

By:

Hata, Saori;
Omori, Chiori;
Kimura, Ayano;
Saito, Haruka;
Kimura, Nobuyuki;
Gupta, Veer;
Pedrini, Steve;
Hone, Eugene;
Chatterjee, Pratishtha;
Taddei, Kevin;
Kasuga, Kensaku;
Ikeuchi, Takeshi;
Waragai, Masaaki;
Nishimura, Masaki;
Hu, Anqi;
Nakaya, Tadashi;
Meijer, Laurent;
Maeda, Masahiro;
Yamamoto, Tohru;
Masters, Colin L.

Publication type:

Article

P3‐184: ALTERED LEVELS OF P3‐ALCβ PEPTIDES IN THE CSF OF AGED MONKEYS AND ALZHEIMER'S DISEASE PATIENTS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1000, doi. 10.1016/j.jalz.2019.06.3213

By:

Hata, Saori;
Kimura, Ayano;
Saito, Haruka;
Waragai, Masaaki;
Ikeuchi, Takeshi;
Martins, Ralph N.;
Kimura, Nobuyuki;
Nishimura, Masaki;
Suzuki, Toshiharu

Publication type:

Article

LEVEL OF P3-ALCβ PEPTIDES ALTER IN CSF OF AD PATIENTS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1013, doi. 10.1016/j.jalz.2017.06.1415

By:

Hata, Saori;
Kimura, Ayano;
Waragai, Masaaki;
Ikeuchi, Takeshi;
Martins, Ralph N.;
Kimura, Nobuyuki;
Nishimura, Masaki;
Suzuki, Toshiharu

Publication type:

Article

Involvement of X11/X11L in Alzheimer's-related beta-amyloid generation and epileptogenesis

Published in:

2012

By:

Kanada, Yoshihilo;
Saito, Yuhki;
Nishimura, Masaki;
Kimura, Nobuyuki;
Suzuki, Toshiharu

Publication type:

Abstract

Membrane microdomain localization of APP c-terminal fragments regulated by the phosphorylation at cytoplasmic Thr668 residue

Published in:

2012

By:

Matsushima, Takahide;
Saito, Yuhki;
Nishimura, Masaki;
Kimura, Nobuyuki;
Hata, Saori;
Suzuki, Toshiharu

Publication type:

Abstract

Age-related modulation of gamma-secretase activity in monkey brains

Published in:

2012

By:

Nishimura, Masaki;
Nakamura, Shinichiro;
Kimura, Nobuyuki;
Suzuki, Toshiharu;
Tooyama, Ikuo

Publication type:

Abstract

Dynein dysfunction causes the disturbance of synaptic vesicle transport and axonal swelling

Published in:

2011

By:

Kimura, Nobuyuki;
Okabayashi, Sachi;
Ono, Fumiko

Publication type:

Abstract

Identification of a gene which controls Abeta accumulation using APP Tg mice with mixed genetic Background Splicing variant specific effect of Kinesin Light Chain 1 (Klc1)

Published in:

2011

By:

Yokokoji, Mikiko;
Takashi, Morihara;
Hayashi, Noriyuki;
Okochi, Masayasu;
Suzuki, Toshiharu;
Saito, Yuhki;
Kimura, Nobuyuki;
Takeda, Masatoshi;
Kazui, Hiroaki;
Akatsu, Hiroyasu;
Takamura, Akitaka;
Katayama, Taiichi;
Ito, Naohiro;
Tatsumi, Shinichi;
Kato, Kiyoko;
Yanagida, Kanta;
Kodama, Takashi;
Tagami, Shinji;
Tanaka, Norihisa;
Kudo, Takashi

Publication type:

Abstract

Dynein dysfunction induces multi-endocytic pathology and endosomal accumulation of APP leading to beta-site cleavage

Published in:

2010

By:

Kimura, Nobuyuki;
Inoue, Makoto;
Okabayashi, Sachi;
Ono, Fumiko;
Negishi, Takayuki

Publication type:

Abstract

Overexpression of wild type TDP-43 in motoneuron of non-human primate

Published in:

2010

By:

Yokota, Takanori;
Uchida, Azusa;
Sasaguri, Hiroki;
Kimura, Nobuyuki;
Uchihara, Toshiki;
Mizusawa, Hidehiro

Publication type:

Abstract

Immunohistochemical analyses of GM1-ganglioside-bound amyloid β-protein in various aged cynomolgus monkey brains

Published in:

2009

By:

Kimura, Nobuyuki;
Yanagisawa, Katsuhiko

Publication type:

Abstract

LGI3 associates with astroglial response against Abeta and accumulates in aged monkey brains

Published in:

2009

By:

Okabayashi, Sachi;
Kimura, Nobuyuki

Publication type:

Abstract

P3-411: Age-related changes of axonal transport motor proteins: siRNA-induced down-regulation causes accumulation of tau and APP

Published in:

2008

By:

Kimura, Nobuyuki;
Imamura, Osamu;
Ono, Fumiko;
Terao, Keiji

Publication type:

Abstract

P3-342: Abeta upregulates BDNF production from astrocytes: Rescue of neurons from abeta-related synaptic impairment

Published in:

2006

By:

Kimura, Nobuyuki;
Takahashi, Masaki;
Tashiro, Tomoko;
Terao, Keiji

Publication type:

Abstract

P3-342: Abeta upregulates BDNF production from astrocytes: Rescue of neurons from abeta-related synaptic impairment

Published in:

2006

By:

Kimura, Nobuyuki;
Takahashi, Masaki;
Tashiro, Tomoko;
Terao, Keiji

Publication type:

Abstract

Transient Behavior of Gas Entrainment Caused by Surface Vortex.

Published in:

Heat Transfer Engineering, 2008, v. 29, n. 8, p. 659, doi. 10.1080/01457630801980574

By:

Ezure, Toshiki;
Kimura, Nobuyuki;
Hayashi, Kenji;
Kamide, Hideki

Publication type:

Article