Works matching AU Kimber, Ian

Results: 159

Can animal models predict food allergenicity?

Published in:

Nutrition Bulletin, 2001, v. 26, n. 2, p. 127, doi. 10.1046/j.1467-3010.2001.00125.x

By:

Kimber,, Ian;
Kimber, Ian;
Dearman, Rebecca J.

Publication type:

Article

New approach methodologies (NAMs): identifying and overcoming hurdles to accelerated adoption.

Published in:

Toxicology Research, 2024, v. 13, n. 2, p. 1, doi. 10.1093/toxres/tfae044

By:

Sewell, Fiona;
Alexander-White, Camilla;
Brescia, Susy;
Currie, Richard A;
Roberts, Ruth;
Roper, Clive;
Vickers, Catherine;
Westmoreland, Carl;
Kimber, Ian

Publication type:

Article

Skin and respiratory chemical allergy: confluence and divergence in a hybrid adverse outcome pathway.

Published in:

Toxicology Research, 2018, v. 7, n. 4, p. 586, doi. 10.1039/c7tx00272f

By:

Kimber, Ian;
Poole, Alan;
Basketter, David A.

Publication type:

Article

Using problem formulation to clarify the meaning of weight of evidence and biological relevance in environmental risk assessments for genetically modified crops.

Published in:

GM Crops & Food, 2019, v. 10, n. 2, p. 63, doi. 10.1080/21645698.2019.1621615

By:

Raybould, Alan;
Holt, Karen;
Kimber, Ian

Publication type:

Article

Workshop on Status of Test Methods for Assessing Potential of Chemicals to Induce Respiratory Allergic Reactions.

Published in:

Inhalation Toxicology, 1994, v. 6, n. 3, p. 303, doi. 10.3109/08958379408995238

By:

Selgrade, Maryjane K.;
Zeiss, C. Raymond;
Karol, Meryl H.;
Sarlo, Katherine;
Kimber, Ian;
Tepper, Jeffrey S.;
Henry, Mary C.

Publication type:

Article

Adverse Outcome Pathways can drive non-animal approaches for safety assessment.

Published in:

Journal of Applied Toxicology, 2015, v. 35, n. 9, p. 971, doi. 10.1002/jat.3165

By:

Burden, Natalie;
Sewell, Fiona;
Andersen, Melvin E.;
Boobis, Alan;
Chipman, J. Kevin;
Cronin, Mark T. D.;
Hutchinson, Thomas H.;
Kimber, Ian;
Whelan, Maurice

Publication type:

Article

Diisocyanates, occupational asthma and IgE antibody: implications for hazard characterization.

Published in:

Journal of Applied Toxicology, 2014, v. 34, n. 10, p. 1073, doi. 10.1002/jat.3041

By:

Kimber, Ian;
Dearman, Rebecca J.;
Basketter, David A.

Publication type:

Article

Characterization of the allergenic potential of proteins: an assessment of the kiwifruit allergen actinidin.

Published in:

Journal of Applied Toxicology, 2014, v. 34, n. 5, p. 489, doi. 10.1002/jat.2897

By:

Dearman, Rebecca J.;
Beresford, Lorna;
Foster, Emily S.;
McClain, Scott;
Kimber, Ian

Publication type:

Article

Computational chemistry, systems biology and toxicology. Harnessing the chemistry of life: revolutionizing toxicology. A commentary.

Published in:

Journal of Applied Toxicology, 2011, v. 31, n. 3, p. 206, doi. 10.1002/jat.1666

By:

Kimber, Ian;
Humphris, Colin;
Westmoreland, Carl;
Alepee, Nathalie;
Negro, Gianni Dal;
Manou, Irene

Publication type:

Article

Skin sensitization, false positives and false negatives: experience with guinea pig assays.

Published in:

Journal of Applied Toxicology, 2010, v. 30, n. 5, p. 381, doi. 10.1002/jat.1545

By:

Baskettera, David A.;
Kimber, Ian

Publication type:

Article

Letter to the Editor.

Published in:

2010

By:

Basketter, David;
Kimber, Ian

Publication type:

Letter

Updating the skin sensitization in vitro data assessment paradigm in 2009.

Published in:

Journal of Applied Toxicology, 2009, v. 29, n. 6, p. 545, doi. 10.1002/jat.1443

By:

Basketter, David A.;
Kimber, Ian

Publication type:

Article

Cytokine profiling of chemical allergens in mice: impact of mitogen on selectivity of response.

Published in:

Journal of Applied Toxicology, 2009, v. 29, n. 3, p. 233, doi. 10.1002/jat.1401

By:

Dearman, Rebecca Jane;
Betts, Catherine Jean;
Caddick, Helen Theresa;
Kimber, Ian

Publication type:

Article

Butyl benzyl phthalate: effects on immune responses to ovalbumin in mice.

Published in:

Journal of Applied Toxicology, 2009, v. 29, n. 2, p. 118, doi. 10.1002/jat.1388

By:

Dearman, Rebecca Jane;
Betts, Catherine Jean;
Beresford, Lorna;
Bailey, Laura;
Caddick, Helen Theresa;
Kimber, Ian

Publication type:

Article

The reduced local lymph node assay: the impact of group size.

Published in:

Journal of Applied Toxicology, 2008, v. 28, n. 4, p. 518, doi. 10.1002/jat.1303

By:

Ryan, Cindy A.;
Chaney, Joel G.;
Kern, Petra S.;
Pattewicz, Grace Y.;
Basketter, David A.;
Betts, Catherine J.;
Dearman, Rebecca J.;
Kimber, Ian;
Gerberick, G. Frank

Publication type:

Article

Chemical Respiratory Allergy and Occupational Asthma: What Are the Key Areas of Uncertainty?

Published in:

2008

By:

Lsola, Daniel;
Kimber, Ian;
Sarlo, Katherine;
Lalko, Jon;
Sipes, Glenn I.

Publication type:

Proceeding

Chemical pollution, respiratory allergy and asthma: a perspective.

Published in:

Journal of Applied Toxicology, 2008, v. 28, n. 1, p. 1, doi. 10.1002/jat.1294

By:

Evans, Gareth S.;
Cadogan, David;
Flueckiger, Andreas;
Hennes, Christa;
Kimber, Ian

Publication type:

Article

B220 analysis with the local lymph node assay: proposal for a more flexible prediction model.

Published in:

Journal of Applied Toxicology, 2007, v. 27, n. 5, p. 506, doi. 10.1002/jat.1269

By:

Betts, Catherine J.;
Dearman, Rebecca J.;
Kimber, Ian;
Ryan, Cindy A.;
Gerberick, G. Frank;
Laiko, Jon;
Api, Anne Marie

Publication type:

Article

A future approach to measuring relative skin sensitising potency: a proposal.

Published in:

Journal of Applied Toxicology, 2006, v. 26, n. 4, p. 341, doi. 10.1002/jat.1146

By:

Jowsey, Ian R.;
Basketter, David A.;
Westmoreland, Carl;
Kimber, Ian

Publication type:

Article

Advantage of using CBA/N strain mice in a non-radioisotopic modification of the local lymph node assay.

Published in:

Journal of Applied Toxicology, 2006, v. 26, n. 1, p. 5, doi. 10.1002/jat.1096

By:

Takeyoshi, Masahiro;
Noda, Shuji;
Yamasaki, Kanji;
Kimber, Ian

Publication type:

Article

Interleukins 5 and 13 Characterize Immune Responses to Respiratory Sensitizing Acid Anhydrides.

Published in:

Journal of Applied Toxicology, 2002, v. 22, n. 5, p. 317, doi. 10.1002/jat.865

By:

Dearman, Rebecca J.;
Filby, Andrew;
Humphreys, Ian R.;
Kimber, Ian

Publication type:

Article

Allergen-induced Changes in Interleukin 1Β (IL-1Β) mRNA Expression by Human Blood-derived Denderitic Cells: Inter-individual Differences and Relevance for Sensitization Testing.

Published in:

Journal of Applied Toxicology, 2001, v. 21, n. 2, p. 115, doi. 10.1002/jat.742

By:

Pichowski, Johanna S.;
Cumberbatch, Marie;
Dearman, Rebecca J.;
Basketter, David A.;
Kimber, Ian

Publication type:

Article

Characterization in Mice of the Immunological Properties of Five Allergenic Acid Anhydrides.

Published in:

Journal of Applied Toxicology, 2000, v. 20, n. 3, p. 221, doi. 10.1002/(SICI)1099-1263(200005/06)20:3<221::AID-JAT651>3.0.CO;2-#

By:

Dearman, Rebecca J.;
Warbrick, E. Vicky;
Humphreys, Ian R.;
Kimber, Ian

Publication type:

Article

A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses.

Published in:

Journal of Applied Toxicology, 1999, v. 19, n. 4, p. 261, doi. 10.1002/(SICI)1099-1263(199907/08)19:4<261::AID-JAT572>3.0.CO;2-5

By:

David A. Basketter;
Linda J Lea;
Andrea Dickens;
David Briggs;
Ian Pate;
Rebecca J. Dearman;
Ian Kimber

Publication type:

Article

Comparative analysis of skin sensitization potency of acrylates (methyl acrylate, ethyl acrylate, butyl acrylate, and ethylhexyl acrylate) using the local lymph node assay.

Published in:

Contact Dermatitis (01051873), 2007, v. 57, n. 4, p. 242, doi. 10.1111/j.1600-0536.2007.01215.x

By:

Dearman, Rebecca J.;
Betts, Catherine J.;
Farr, Craig;
McLaughlin, James;
Berdasco, Nancy;
Wiench, Karin;
Kimber, Ian

Publication type:

Article

The local lymph node assay and the assessment of relative potency: status of validation.

Published in:

Contact Dermatitis (01051873), 2007, v. 57, n. 2, p. 70, doi. 10.1111/j.1600-0536.2007.01141.x

By:

Basketter, David A.;
Gerberick, Frank;
Kimber, Ian

Publication type:

Article

Oral tolerance to contact allergens: a common occurrence? A review.

Published in:

Contact Dermatitis (01051873), 2007, v. 56, n. 5, p. 247, doi. 10.1111/j.1600-0536.2006.01066.x

By:

White, Jonathan M. L.;
Goon, Anthony T. J.;
Jowsey, Ian R.;
Basketter, David A.;
Mak, Rose K. H.;
Kimber, Ian;
McFadden, John P.

Publication type:

Article

Information derived from sensitization test methods: test sensitivity, false positives and false negatives.

Published in:

Contact Dermatitis (01051873), 2007, v. 56, n. 1, p. 1, doi. 10.1111/j.1600-0536.2007.01009.x

By:

Basketter, David A.;
Kimber, Ian

Publication type:

Article

Skin sensitization potency of methyl methacrylate in the local lymph node assay: comparisons with guinea-pig data and human experience.

Published in:

Contact Dermatitis (01051873), 2006, v. 55, n. 3, p. 140, doi. 10.1111/j.1600-0536.2006.00898.x

By:

Betts, Catherine J.;
Dearman, Rebecca J.;
Heylings, Jon R.;
Kimber, Ian;
Basketter, David A.

Publication type:

Article

The local lymph node assay and skin sensitization: a cut-down screen to reduce animal requirements?

Published in:

Contact Dermatitis (01051873), 2006, v. 54, n. 4, p. 181, doi. 10.1111/j.0105-1873.2006.00827.x

By:

Kimber, Ian;
Dearman, Rebecca J.;
Betts, Catherine J.;
Gerberick, G. Frank;
Ryan, Cindy A.;
Kern, Petra S.;
Patlewicz, Grace Y.;
Basketter, David A.

Publication type:

Article

Predictive identification of human skin sensitization thresholds.

Published in:

Contact Dermatitis (01051873), 2005, v. 53, n. 5, p. 260, doi. 10.1111/j.0105-1873.2005.00707.x

By:

Basketter, David A.;
Clapp, Catherine;
Jefferies, Donna;
Safford, Bob;
Ryan, Cindy A.;
Gerberick, Frank;
Dearman, Rebecca J.;
Kimber, Ian

Publication type:

Article

Potency and risk assessment of a skin-sensitizing disperse dye using the local lymph node assay.

Published in:

Contact Dermatitis (01051873), 2005, v. 52, n. 5, p. 268, doi. 10.1111/j.0105-1873.2005.00578.x

By:

Betts, Catherine J.;
Dearman, Rebecca J.;
Kimber, Ian;
Maibach, Howard I.

Publication type:

Article

Thresholds of contact sensitization from disperse dyes in textiles.

Published in:

2005

By:

Kimber, Ian;
Maibach, Howard I.;
Msotschi, Herbert

Publication type:

Letter

Evaluation of the skin sensitizing potency of chemicals by using the existing methods and considerations of relevance for elicitation.

Published in:

Contact Dermatitis (01051873), 2005, v. 52, n. 1, p. 39, doi. 10.1111/j.0105-1873.2005.00490.x

By:

Basketter, David A.;
Andersen, Klaus E.;
Liden, Carola;
Loveren, Henk Van;
Boman, Anders;
Kimber, Ian;
Alanko, Kristiina;
Berggren, Elisabet

Publication type:

Article

A chemical dataset for evaluation of alternative approaches to skin-sensitization testing.

Published in:

Contact Dermatitis (01051873), 2004, v. 50, n. 5, p. 274, doi. 10.1111/j.0105-1873.2004.00290.x

By:

Gerberick, G. Frank;
Ryan, Cindy A.;
Kern, Petra S.;
Dearman, Rebecca J.;
Kimber, Ian;
Patlewicz, Grace Y.;
Basketter, David A.

Publication type:

Article

The local lymph node assay: past, present and future.

Published in:

Contact Dermatitis (01051873), 2002, v. 47, n. 6, p. 315, doi. 10.1034/j.1600-0536.2002.470601.x

By:

Kimber, Ian;
Dearman, R. J.;
Basketter, D. A.;
Ryan, C. A.;
Gerberick, G. F.

Publication type:

Article

Allergic contact dermatitis: the cellular effectors.

Published in:

Contact Dermatitis (01051873), 2002, v. 46, n. 1, p. 1, doi. 10.1034/j.1600-0536.2002.460101.x

By:

Kimber, Ian;
Dearman, Rebecca J

Publication type:

Article

Human potency predictions for aldehydes using the local lymph node assay.

Published in:

Contact Dermatitis (01051873), 2001, v. 45, n. 2, p. 89, doi. 10.1034/j.1600-0536.2001.045002089.x

By:

Basketter, David A.;
Wright, Zoe M.;
Warbrick, E. Vicky;
Dearman, Rebecca J.;
Kimber, Ian;
Ryan, Cindy A.;
Gerberick, G. Frank;
White, Ian R.

Publication type:

Article

The suitability of hexyl cinnamic aldehyde as a calibrant for the murine local lymph node assay.

Published in:

Contact Dermatitis (01051873), 2001, v. 44, n. 6, p. 357, doi. 10.1034/j.1600-0536.2001.044006357.x

By:

Dearman, Rebecca J.;
Wright, Zoe M.;
Basketter, David A.;
Ryan, Cindy A.;
Gerberick, G. Frank;
Kimber, Ian

Publication type:

Article

Influence of application vehicle on skin sensitization to methylchloroisothiazolinone/methylisothiazolinone: analysis using the local lymph node assay.

Published in:

Contact Dermatitis (01051873), 1999, v. 41, n. 6, p. 325, doi. 10.1111/j.1600-0536.1999.tb06181.x

By:

Warbrick, E. Vicky;
Dearman, Rebecca J.;
Basketter, David A.;
Kimber, Ian

Publication type:

Article

Skin sensitization risk assessment: a comparative evaluation of 3 isothiazolinone biocides.

Published in:

Contact Dermatitis (01051873), 1999, v. 40, n. 3, p. 150, doi. 10.1111/j.1600-0536.1999.tb06013.x

By:

Basketter, David A.;
Rodford, Rosemary;
Kimber, Ian;
Smith, Ian;
Wahlberg, Jane E.

Publication type:

Article

Dinitrohalobenzenes: evaluation of relative skin sensitization potential using the local lymph node assay.

Published in:

Contact Dermatitis (01051873), 1997, v. 36, n. 2, p. 97, doi. 10.1111/j.1600-0536.1997.tb00421.x

By:

Basketter, David A.;
Dearman, Rebecca J.;
Hilton, Jennifer;
Kimber, Ian

Publication type:

Article

Olive oil: suitability for use as a vehicle in the local lymph node assay.

Published in:

Contact Dermatitis (01051873), 1996, v. 35, n. 3, p. 190, doi. 10.1111/j.1600-0536.1996.tb02353.x

By:

Basketter, David A.;
Kimber, Ian

Publication type:

Article

Dichloronitrobenzene: a reappraisal of its skin sensitization potential.

Published in:

Contact Dermatitis (01051873), 1996, v. 34, n. 1, p. 55, doi. 10.1111/j.1600-0536.1996.tb02113.x

By:

Basketter, David A.;
Scholes, Edward W.;
Fielding, Ian;
Dearman, Rebecca J.;
Hilton, Jennifer;
Kimber, Ian

Publication type:

Article

Streptozotocin: inherent but not expressed skin sensitizing activity.

Published in:

Contact Dermatitis (01051873), 1995, v. 33, n. 3, p. 165, doi. 10.1111/j.1600-0536.1995.tb00538.x

By:

Ashby, John;
Hilton, Jenniefer;
Dearman, Rebecca J.;
Kimber, Ian

Publication type:

Article

Serological markers of the elicitation reaction in allergic contact dermatitis.

Published in:

Contact Dermatitis (01051873), 1990, v. 23, n. 4, p. 235, doi. 10.1111/j.1600-0536.1990.tb05008.x

By:

Kimber, Ian;
Cumberbatch, Marie;
Coleman, John W.;
Hopkins, Stephen J.

Publication type:

Article

Direct interaction between antigen-bearing dendritic cells and T-lymphocytes during the induction phase of allergic contact dermatitis.

Published in:

Contact Dermatitis (01051873), 1990, v. 23, n. 4, p. 234, doi. 10.1111/j.1600-0536.1990.tb05006.x

By:

Kimber, Ian;
Illingworth, Ian;
Cmberbatch, Marie

Publication type:

Article

The murine local lymph node assay for identification of contact allergens: a preliminary evaluation of in situ measurement of lymphocyte proliferation.

Published in:

Contact Dermatitis (01051873), 1989, v. 21, n. 4, p. 215, doi. 10.1111/j.1600-0536.1989.tb03198.x

By:

Kimber, Ian;
Hilton, Jennifer;
Weisenberger, Claudia

Publication type:

Article

ASSESSMENT OF THE SKIN SENSITIZATION POTENTIAL OF TOPICAL MEDICAMENTS USING THE LOCAL LYMPH NODE ASSAY: AN INTERLABORATORY EVALUATION.

Published in:

Journal of Toxicology & Environmental Health: Part A, 1998, v. 53, n. 7, p. 563, doi. 10.1080/009841098159141

By:

Kimber, Ian;
Hilton, Jennifer;
Dearman, Rebecca J.;
Gerberick, G. Frank;
Ryan, Cindy A.;
Basketter, David A.;
Lea, Linda;
House, Robert V.;
Ladics, Gregory S.;
Loveless, Scott E.;
Hastings, Kenneth L.

Publication type:

Article

Extended fragrance ingredients surveillance study (EFISS)—protocol for a clinical surveillance study on contact allergy to 7 fragrance materials in widespread use but hitherto not systematically patch tested.

Published in:

Archives of Dermatological Research, 2025, v. 317, n. 1, p. 1, doi. 10.1007/s00403-025-04286-9

By:

Uter, Wolfgang;
Figueiredo, Ana Carolina;
Belloni Fortina, Anna;
Bourke, John;
Bridges, Jim;
Gonçalo, Margarida;
Gregoriou, Stamatis;
Lang, Claudia;
Ljubojević Hadžavdić, Suzana;
Huggard, Joseph;
Isaksson, Marléne;
Jöckel, Karl-Heinz;
Kimber, Ian;
Koumaki, Dimitra;
Pezzolo, Elena;
Rustemeyer, Thomas;
Schuttelaar, Marie L. A.;
Svedman, Cecilia;
Vey, Matthias;
White, Ian

Publication type:

Article