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The TGFβ type I receptor kinase inhibitor vactosertib in combination with pomalidomide in relapsed/refractory multiple myeloma: a phase 1b trial.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51442-2
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- Publication type:
- Article
Pharmacokinetic characteristics of vactosertib, a new activin receptor-like kinase 5 inhibitor, in patients with advanced solid tumors in a first-in-human phase 1 study.
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 3, p. 812, doi. 10.1007/s10637-019-00835-y
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- Publication type:
- Article
Homozygous deletions at 3p22, 5p14, 6q15, and 9p21 result in aberrant expression of tumor suppressor genes in gastric cancer.
- Published in:
- Genes, Chromosomes & Cancer, 2015, v. 54, n. 3, p. 142, doi. 10.1002/gcc.22226
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- Publication type:
- Article
Oral transforming growth factor‐beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti‐tumor immunity.
- Published in:
- Cancer Communications, 2024, v. 44, n. 8, p. 884, doi. 10.1002/cac2.12589
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- Publication type:
- Article
Effects of MHY908, a New Synthetic PPARα/γ Dual Agonist, on Inflammatory Responses and Insulin Resistance in Aged Rats.
- Published in:
- 2016
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- Publication type:
- journal article
Infrared luminosity functions based on 18 mid-infrared bands: revealing cosmic star formation history with AKARI and Hyper Suprime-Cam.
- Published in:
- Publications of the Astronomical Society of Japan, 2019, v. 71, n. 2, p. N.PAG, doi. 10.1093/pasj/psz009
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- Publication type:
- Article
Does AGN fraction depend on redshift or luminosity? An extinction-free test by 18-band near- to mid-infrared SED fitting in the AKARI NEP wide field.
- Published in:
- Publications of the Astronomical Society of Japan, 2019, v. 71, n. 2, p. N.PAG, doi. 10.1093/pasj/psz012
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- Publication type:
- Article
Herschel-PACS North Ecliptic Pole Survey.
- Published in:
- Publications of the Astronomical Society of Japan, 2019, v. 71, n. 1, p. N.PAG, doi. 10.1093/pasj/psy107
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- Publication type:
- Article
Characteristics of mid-infrared PAH emission from star-forming galaxies selected at 250 μm in the North Ecliptic Pole field.
- Published in:
- Publications of the Astronomical Society of Japan, 2019, v. 71, n. 1, p. N.PAG, doi. 10.1093/pasj/psy121
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- Publication type:
- Article
Cytoplasmic LMO2-LDB1 Complex Activates STAT3 Signaling through Interaction with gp130-JAK in Glioma Stem Cells.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 13, p. N.PAG, doi. 10.3390/cells11132031
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- Publication type:
- Article
Circulating Cell-Free mtDNA Contributes to AIM2 Inflammasome-Mediated Chronic Inflammation in Patients with Type 2 Diabetes.
- Published in:
- Cells (2073-4409), 2019, v. 8, n. 4, p. 328, doi. 10.3390/cells8040328
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- Publication type:
- Article
Caspase-mediated Cdk2 activation is a critical step to execute transforming growth factor-β1-induced apoptosis in human gastric cancer cells.
- Published in:
- Oncogene, 2001, v. 20, n. 10, p. 1254, doi. 10.1038/sj.onc.1204203
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- Publication type:
- Article
Sequence-specific enhancer binding protein is responsible for the differential expression of ERT/ESX/ELF-3/ESE-1/jen gene in human gastric cancer cell lines: Implication for the loss of TGF-β type II receptor expression.
- Published in:
- Oncogene, 2001, v. 20, n. 10, p. 1235, doi. 10.1038/sj.onc.1204227
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- Publication type:
- Article
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.
- Published in:
- Oncogene, 2000, v. 19, n. 15, p. 1868, doi. 10.1038/sj.onc.1203504
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- Publication type:
- Article
Over-expression of ERT(ESX/ESE-1/ELF3), an ets-related transcription factor, induces endogenous TGF-β type II receptor expression and restores the TGF-β signaling pathway in Hs578t human breast cancer cells.
- Published in:
- Oncogene, 2000, v. 19, n. 1, p. 151, doi. 10.1038/sj.onc.1203252
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- Publication type:
- Article
Transcriptional repression of the transforming growth factor-β type I receptor gene by DNA methylation results in the development of TGF-β resistance in human gastric cancer.
- Published in:
- Oncogene, 1999, v. 18, n. 51, p. 7280, doi. 10.1038/sj.onc.1203146
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- Publication type:
- Article
Truncation of the TGF-β type II receptor gene results in insensitivity to TGF-β in human gastric cancer cells.
- Published in:
- Oncogene, 1999, v. 18, n. 13, p. 2213, doi. 10.1038/sj.onc.1202535
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- Publication type:
- Article
The human hepatitis B virus transactivator X gene product regulates Sp1 mediated transcription of an insulin-like growth factor II promoter 4.
- Published in:
- Oncogene, 1998, v. 16, n. 18, p. 2367, doi. 10.1038/sj.onc.1201760
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- Publication type:
- Article
Antimicrobial efficacy of granulysin-derived synthetic peptides in acne vulgaris.
- Published in:
- International Journal of Dermatology, 2015, v. 54, n. 7, p. 853, doi. 10.1111/ijd.12756
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- Publication type:
- Article
Paraneoplastic erythromelalgia associated with breast carcinoma.
- Published in:
- International Journal of Dermatology, 2012, v. 51, n. 7, p. 878, doi. 10.1111/j.1365-4632.2010.04643.x
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- Publication type:
- Article
Transcriptional inactivation of the tissue inhibitor of metalloproteinase-3 gene by dna hypermethylation of the 5'-CpG island in human gastric cancer cell lines.
- Published in:
- International Journal of Cancer, 2000, v. 86, n. 5, p. 632, doi. 10.1002/(SICI)1097-0215(20000601)86:5<632::AID-IJC5>3.0.CO;2-5
- By:
- Publication type:
- Article
Genetic integrity of transforming growth factor β (TGF-β) receptors in cervical carcinoma cell lines: loss of growth sensitivity but conserved transcriptional response to TGF-β.
- Published in:
- International Journal of Cancer, 1998, v. 77, n. 4, p. 620, doi. 10.1002/(SICI)1097-0215(19980812)77:4<620::AID-IJC23>3.0.CO;2-8
- By:
- Publication type:
- Article
N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer.
- Published in:
- Cell Death & Disease, 2023, v. 14, n. 8, p. 1, doi. 10.1038/s41419-023-06083-6
- By:
- Publication type:
- Article
Combination treatment of T1-44, a PRMT5 inhibitor with Vactosertib, an inhibitor of TGF-β signaling, inhibits invasion and prolongs survival in a mouse model of pancreatic tumors.
- Published in:
- Cell Death & Disease, 2023, v. 14, n. 2, p. 1, doi. 10.1038/s41419-023-05630-5
- By:
- Publication type:
- Article
Degradation of DRAK1 by CUL3/SPOP E3 Ubiquitin ligase promotes tumor growth of paclitaxel-resistant cervical cancer cells.
- Published in:
- Cell Death & Disease, 2022, v. 13, n. 2, p. 1, doi. 10.1038/s41419-022-04619-w
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- Publication type:
- Article
Identification of Genetic Factors Underlying the Association between Sodium Intake Habits and Hypertension Risk.
- Published in:
- Nutrients, 2020, v. 12, n. 9, p. 2580, doi. 10.3390/nu12092580
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- Publication type:
- Article
Trends in Invasive Pneumococcal Disease in Cancer Patients After the Introduction of 7-valent Pneumococcal Conjugate Vaccine: A 20-year Longitudinal Study at a Major Urban Cancer Center.
- Published in:
- Clinical Infectious Diseases, 2018, v. 66, n. 2, p. 244, doi. 10.1093/cid/cix739
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- Publication type:
- Article
Subepidermal calcified nodules and syringoma.
- Published in:
- 1997
- By:
- Publication type:
- Letter
Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair.
- Published in:
- Cellular & Molecular Life Sciences, 2015, v. 72, n. 3, p. 583, doi. 10.1007/s00018-014-1687-z
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- Publication type:
- Article
Peptidyl‐prolyl cis‐trans isomerase NIMA‐interacting 1 directly binds and stabilizes Nrf2 in breast cancer.
- Published in:
- FASEB Journal, 2022, v. 36, n. 1, p. 1, doi. 10.1096/fj.202100776RR
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- Publication type:
- Article
Smad4 signalling in T cells is required for suppression of gastrointestinal cancer.
- Published in:
- 2006
- By:
- Publication type:
- Correction notice
Comparative analysis of skin characteristics evaluation by a dermatologist and the Janus‐III measurement system.
- Published in:
- Skin Research & Technology, 2021, v. 27, n. 1, p. 86, doi. 10.1111/srt.12915
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- Publication type:
- Article
Sea water or it's components alter experimental irritant dermatitis in man.
- Published in:
- Skin Research & Technology, 2001, v. 7, n. 1, p. 36, doi. 10.1034/j.1600-0846.2001.007001036.x
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- Publication type:
- Article
Tropomyosin-receptor kinase fused gene (TFG) regulates lipid production in human sebocytes.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43209-3
- By:
- Publication type:
- Article
MAST4 controls cell cycle in spermatogonial stem cells.
- Published in:
- Cell Proliferation, 2023, v. 56, n. 4, p. 1, doi. 10.1111/cpr.13390
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- Publication type:
- Article
Neural stem cells derived from the developing forebrain of YAC128 mice exhibit pathological features of Huntington's disease.
- Published in:
- Cell Proliferation, 2020, v. 53, n. 10, p. 1, doi. 10.1111/cpr.12893
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- Publication type:
- Article
Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells.
- Published in:
- Nature Communications, 2015, v. 6, n. 8, p. 8039, doi. 10.1038/ncomms9039
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- Publication type:
- Article
Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6.
- Published in:
- Nature Communications, 2013, v. 4, n. 10, p. 2562, doi. 10.1038/ncomms3562
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- Publication type:
- Article
Characteristics of vocalisation in Hanwoo cattle (Bos taurus coreanae) under different call-causing conditions.
- Published in:
- Animal Production Science, 2019, v. 59, n. 12, p. 2169, doi. 10.1071/AN17698
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- Publication type:
- Article
Mechanical and barrier properties of poly(lactic acid) films coated by nanoclay-ink composition.
- Published in:
- Journal of Applied Polymer Science, 2013, v. 127, n. 5, p. 3823, doi. 10.1002/app.37663
- By:
- Publication type:
- Article
FLEX-IoT: Secure and Resource-Efficient Network Boot System for Flexible-IoT Platform.
- Published in:
- Sensors (14248220), 2021, v. 21, n. 6, p. 2060, doi. 10.3390/s21062060
- By:
- Publication type:
- Article
Disruption of Membrane Integrity as a Molecular Initiating Event Determines the Toxicity of Polyhexamethylene Guanidine Phosphate Depending on the Routes of Exposure.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3289, doi. 10.3390/ijms23063289
- By:
- Publication type:
- Article
Generation of a Novel Transgenic Zebrafish for Studying Adipocyte Development and Metabolic Control.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 3994, doi. 10.3390/ijms22083994
- By:
- Publication type:
- Article
Mechanistic Aspects of Green Tea as a Cancer Preventive: Effect of Components on Human Stomach Cancer Cell Lines.
- Published in:
- Cancer Science, 1999, v. 90, n. 7, p. 733, doi. 10.1111/j.1349-7006.1999.tb00808.x
- By:
- Publication type:
- Article
Efficacy of brincidofovir as prophylaxis against HSV and VZV in hematopoietic cell transplant recipients.
- Published in:
- Transplant Infectious Disease, 2018, v. 20, n. 6, p. N.PAG, doi. 10.1111/tid.12977
- By:
- Publication type:
- Article
Cytomegalovirus resistance in CD34<sup>+</sup>‐selected hematopoietic cell transplant recipients.
- Published in:
- Transplant Infectious Disease, 2018, v. 20, n. 3, p. 1, doi. 10.1111/tid.12881
- By:
- Publication type:
- Article
Defective Localization With Impaired Tumor Cytotoxicity Contributes to the Immune Escape of NK Cells in Pancreatic Cancer Patients.
- Published in:
- Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00496
- By:
- Publication type:
- Article
Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells.
- Published in:
- Oncogene, 2004, v. 23, n. 46, p. 7651, doi. 10.1038/sj.onc.1207924
- By:
- Publication type:
- Article
Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide.
- Published in:
- EMBO Molecular Medicine, 2015, v. 7, n. 5, p. 577, doi. 10.15252/emmm.201404653
- By:
- Publication type:
- Article
(Z)-5-(2,4-Dihydroxybenzylidene)thiazolidine-2,4-dione Prevents UVB-Induced Melanogenesis and Wrinkle Formation through Suppressing Oxidative Stress in HRM-2 Hairless Mice.
- Published in:
- Oxidative Medicine & Cellular Longevity, 2016, p. 1, doi. 10.1155/2016/2761463
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- Publication type:
- Article