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Thirty‐day risk of digoxin toxicity among older adults co‐prescribed trimethoprim‐sulfamethoxazole versus amoxicillin: A population‐based cohort study.
- Published in:
- Pharmacotherapy, 2024, v. 44, n. 7, p. 558, doi. 10.1002/phar.2948
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- Publication type:
- Article
Impact of CYP2C19 metabolizer status on esophageal mucosal inflammation, acid exposure, and motility among patients on chronic proton-pump inhibitor therapy with refractory symptoms of gastroesophageal reflux disease.
- Published in:
- Journal of the Canadian Association of Gastroenterology, 2024, v. 7, n. 3, p. 238, doi. 10.1093/jcag/gwae005
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- Publication type:
- Article
Does prescribing apixaban or rivaroxaban versus warfarin for patients diagnosed with atrial fibrillation save health system costs? A multivalued treatment effects analysis.
- Published in:
- European Journal of Health Economics, 2024, v. 25, n. 3, p. 397, doi. 10.1007/s10198-023-01594-7
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- Publication type:
- Article
Patients' Experiences of a Precision Medicine Clinic.
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- Journal of Patient Experience, 2024, p. 1, doi. 10.1177/23743735241229384
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- Publication type:
- Article
High-Throughput Computing to Automate Population-Based Studies to Detect the 30-Day Risk of Adverse Outcomes After New Outpatient Medication Use in Older Adults with Chronic Kidney Disease: A Clinical Research Protocol.
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- Canadian Journal of Kidney Health & Disease, 2024, p. 1, doi. 10.1177/20543581231221891
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- Publication type:
- Article
Cost-Effectiveness Analysis of Pharmacogenomics (PGx)-Based Warfarin, Apixaban, and Rivaroxaban Versus Standard Warfarin for the Management of Atrial Fibrillation in Ontario, Canada.
- Published in:
- PharmacoEconomics, 2024, v. 42, n. 1, p. 69, doi. 10.1007/s40273-023-01309-z
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- Publication type:
- Article
Low-Dose Methotrexate and Serious Adverse Events Among Older Adults With Chronic Kidney Disease.
- Published in:
- JAMA Network Open, 2023, v. 6, n. 11, p. e2345132, doi. 10.1001/jamanetworkopen.2023.45132
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- Publication type:
- Article
Genetic Variation in miR-27a Is Associated with Fluoropyrimidine-Associated Toxicity in Patients with Dihydropyrimidine Dehydrogenase Variants after Genotype-Guided Dose Reduction.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13284, doi. 10.3390/ijms241713284
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- Article
Thiopurine Methyltransferase Intermediate Metabolizer Status and Thiopurine‐Associated Toxicity During Maintenance Therapy in Childhood Acute Lymphoblastic Leukemia.
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- Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 6, p. 1326, doi. 10.1002/cpt.2894
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- Publication type:
- Article
Adverse events with quetiapine and clarithromycin coprescription: A population‐based retrospective cohort study.
- Published in:
- Health Science Reports, 2023, v. 6, n. 6, p. 1, doi. 10.1002/hsr2.1375
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- Publication type:
- Article
Fluoropyrimidine-associated toxicity and DPYD variants c.85T>C, c.496A>G, and c.1236G>A: impact of haplotype.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 1, p. 97, doi. 10.1007/s00280-022-04491-7
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- Publication type:
- Article
DPYD Exon 4 Deletion Associated with Fluoropyrimidine Toxicity and Importance of Copy Number Variation.
- Published in:
- Current Oncology, 2023, v. 30, n. 1, p. 663, doi. 10.3390/curroncol30010051
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- Publication type:
- Article
A Comparative Analysis of Drug Therapy, Disease Phenotype, and Health Care Outcomes for Men and Women with Inflammatory Bowel Disease.
- Published in:
- Digestive Diseases & Sciences, 2022, v. 67, n. 9, p. 4287, doi. 10.1007/s10620-021-07177-x
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- Publication type:
- Article
Association of Higher-Dose Fluoroquinolone Therapy With Serious Adverse Events in Older Adults With Advanced Chronic Kidney Disease.
- Published in:
- JAMA Network Open, 2022, v. 5, n. 8, p. e2224892, doi. 10.1001/jamanetworkopen.2022.24892
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- Publication type:
- Article
Association of Higher-Dose Fluoroquinolone Therapy With Serious Adverse Events in Older Adults With Advanced Chronic Kidney Disease.
- Published in:
- JAMA Network Open, 2022, v. 5, n. 8, p. 1, doi. 10.1001/jamanetworkopen.2022.24892
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- Publication type:
- Article
Patient‐specific genetic factors predict treatment failure in sofosbuvir‐treated patients with chronic hepatitis C.
- Published in:
- Liver International, 2022, v. 42, n. 4, p. 796, doi. 10.1111/liv.15175
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- Publication type:
- Article
High oncostatin M predicts lack of clinical remission for patients with inflammatory bowel disease on tumor necrosis factor α antagonists.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05208-9
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- Publication type:
- Article
Pharmacogenomic‐based personalized medicine: Multistakeholder perspectives on implementational drivers and barriers in the Canadian healthcare system.
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- CTS: Clinical & Translational Science, 2021, v. 14, n. 6, p. 2231, doi. 10.1111/cts.13083
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- Article
Understanding value in a healthcare setting: An application of the business model canvas.
- Published in:
- Methodological Innovations, 2021, p. 1, doi. 10.1177/20597991211050477
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- Publication type:
- Article
Organic Anion Transporting Polypeptide 2B1 (OATP2B1) Genetic Variants: In Vitro Functional Characterization and Association With Circulating Concentrations of Endogenous Substrates.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.713567
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- Article
Understanding value in a healthcare setting: An application of the business model canvas.
- Published in:
- Methodological Innovations, 2021, v. 14, n. 3, p. 1, doi. 10.1177/20597991211050477
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- Publication type:
- Article
Impact of pretreatment dihydropyrimidine dehydrogenase genotype‐guided fluoropyrimidine dosing on chemotherapy associated adverse events.
- Published in:
- CTS: Clinical & Translational Science, 2021, v. 14, n. 4, p. 1338, doi. 10.1111/cts.12981
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- Publication type:
- Article
Letter: genetic variation in the HLA‐DQA1*05 allele predicts tumour necrosis factor‐α antagonist immunogenicity – does location matter?
- Published in:
- Alimentary Pharmacology & Therapeutics, 2021, v. 53, n. 9, p. 1055, doi. 10.1111/apt.16338
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- Publication type:
- Article
Rosuvastatin Myotoxicity After Starting Canagliflozin Treatment.
- Published in:
- 2021
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- Publication type:
- journal article
High infliximab trough concentrations are associated with sustained histologic remission in inflammatory bowel disease: a prospective cohort study.
- Published in:
- 2021
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- Publication type:
- journal article
Near Miss or Standard of Care? DPYD Screening for Cancer Patients Receiving Fluorouracil.
- Published in:
- Current Oncology, 2021, v. 28, n. 1, p. 94, doi. 10.3390/curroncol28010012
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- Publication type:
- Article
Mouse NTCP–Mediated Rosuvastatin Uptake In Vitro and in Slc10a1-Deficient Mice.
- Published in:
- AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00540-2
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- Article
Rosuvastatin Myotoxicity After Starting Canagliflozin Treatment: A Case Report.
- Published in:
- 2020
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- Publication type:
- case study
Genetic and clinical predictors of arthralgia during letrozole or anastrozole therapy in breast cancer patients.
- Published in:
- Breast Cancer Research & Treatment, 2020, v. 183, n. 2, p. 365, doi. 10.1007/s10549-020-05777-1
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- Publication type:
- Article
Genetic variation in the farnesoid X-receptor predicts Crohn's disease severity in female patients.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68686-9
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- Publication type:
- Article
Letter: immunogenicity of infliximab—ready for routine prediction? Authors' reply.
- Published in:
- Alimentary Pharmacology & Therapeutics, 2020, v. 51, n. 8, p. 813, doi. 10.1111/apt.15684
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- Publication type:
- Article
Attenuation of bile acid-mediated FXR and PXR activation in patients with Crohn's disease.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-58644-w
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- Publication type:
- Article
HLADQA1*05 genotype predicts anti‐drug antibody formation and loss of response during infliximab therapy for inflammatory bowel disease.
- Published in:
- Alimentary Pharmacology & Therapeutics, 2020, v. 51, n. 3, p. 356, doi. 10.1111/apt.15563
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- Publication type:
- Article
Drug interactions and pharmacogenetic factors contribute to variation in apixaban concentration in atrial fibrillation patients in routine care.
- Published in:
- Journal of Thrombosis & Thrombolysis, 2020, v. 49, n. 2, p. 294, doi. 10.1007/s11239-019-01962-2
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- Publication type:
- Article
Precision Medicine: Lessons Learned From Implementation of a Pharmacogenetics‐Based Patient Care Program in a Real‐World Setting.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 5, p. 933, doi. 10.1002/cpt.1611
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- Publication type:
- Article
Apixaban Concentrations with Lower than Recommended Dosing in Older Adults with Atrial Fibrillation.
- Published in:
- Journal of the American Geriatrics Society, 2019, v. 67, n. 9, p. 1902, doi. 10.1111/jgs.15982
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- Publication type:
- Article
Differences in Warfarin Pharmacodynamics and Predictors of Response Among Three Racial Populations.
- Published in:
- 2019
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- Publication type:
- journal article
Targeted next generation sequencing as a tool for precision medicine.
- Published in:
- BMC Medical Genomics, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s12920-019-0527-2
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- Publication type:
- Article
Effect of CYP4F2,VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single‐Patient Data Meta‐Analysis in More Than 15,000 Individuals.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 105, n. 6, p. 1477, doi. 10.1002/cpt.1323
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- Publication type:
- Article
DPYD and Fluorouracil-Based Chemotherapy: Mini Review and Case Report.
- Published in:
- Pharmaceutics, 2019, v. 11, n. 5, p. 199, doi. 10.3390/pharmaceutics11050199
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- Publication type:
- Article
Letrozole concentration is associated with CYP2A6 variation but not with arthralgia in patients with breast cancer.
- Published in:
- Breast Cancer Research & Treatment, 2018, v. 172, n. 2, p. 371, doi. 10.1007/s10549-018-4910-z
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- Publication type:
- Article
Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance.
- Published in:
- Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 5, p. 890, doi. 10.1002/cpt.1112
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- Publication type:
- Article
CYP2D6 genotype and endoxifen plasma concentration do not predict hot flash severity during tamoxifen therapy.
- Published in:
- Breast Cancer Research & Treatment, 2018, v. 171, n. 3, p. 701, doi. 10.1007/s10549-018-4876-x
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- Publication type:
- Article
Food Effect on Rosuvastatin Disposition and Low‐Density Lipoprotein Cholesterol.
- Published in:
- Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 3, p. 525, doi. 10.1002/cpt.973
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- Publication type:
- Article
SLC6A3 Polymorphism Predisposes to Dopamine Overdose in Parkinson's Disease.
- Published in:
- Frontiers in Neurology, 2018, p. N.PAG, doi. 10.3389/fneur.2018.00693
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- Publication type:
- Article
Pharmacogenomics Guided-Personalization of Warfarin and Tamoxifen.
- Published in:
- Journal of Personalized Medicine, 2017, v. 7, n. 4, p. 20, doi. 10.3390/jpm7040020
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- Publication type:
- Article
Genetic Determinants of Clozapine-Induced Metabolic Side Effects.
- Published in:
- 2017
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- Publication type:
- journal article
Impact of Transporter Polymorphisms on Drug Development: Is It Clinically Significant?
- Published in:
- Journal of Clinical Pharmacology, 2016, v. 56, p. S40, doi. 10.1002/jcph.691
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- Publication type:
- Article
Profound reduction in tamoxifen active metabolite endoxifen in a breast cancer patient treated with rifampin prior to initiation of an anti-TNFα biologic for ulcerative colitis: a case report.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Relationships between Endogenous Plasma Biomarkers of Constitutive Cytochrome P450 3 A Activity and Single-Time-Point Oral Midazolam Microdose Phenotype in Healthy Subjects.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2016, v. 118, n. 4, p. 284, doi. 10.1111/bcpt.12492
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- Publication type:
- Article