Works matching AU Kiel, Christina

Results: 47

QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46063-8

By:

Advani, Jayshree;
Mehta, Puja A.;
Hamel, Andrew R.;
Mehrotra, Sudeep;
Kiel, Christina;
Strunz, Tobias;
Corso-Díaz, Ximena;
Kwicklis, Madeline;
van Asten, Freekje;
Ratnapriya, Rinki;
Chew, Emily Y.;
Hernandez, Dena G.;
Montezuma, Sandra R.;
Ferrington, Deborah A.;
Weber, Bernhard H. F.;
Segrè, Ayellet V.;
Swaroop, Anand

Publication type:

Article

Analysis of Ras-effector interaction competition in large intestine and colorectal cancer context.

Published in:

Small GTPases, 2021, v. 12, n. 3, p. 209, doi. 10.1080/21541248.2020.1724596

By:

Ibáňez Gaspar, Verónica;
Catozzi, Simona;
Ternet, Camille;
Luthert, Philip J.;
Kiel, Christina

Publication type:

Article

Integration of Protein Abundance and Structure Data Reveals Competition in the ErbB Signaling Network.

Published in:

Science Signaling, 2013, v. 6, n. 306, p. 1, doi. 10.1126/scisignal.2004560

By:

Kiel, Christina;
Verschueren, Erik;
Jae-Seong Yang;
Serrano, Luis

Publication type:

Article

Cell Type-Specific Importance of Ras-c-Raf Complex Association Rate Constants for MAPK Signaling.

Published in:

Science Signaling, 2009, v. 2, n. 81, p. 1, doi. 10.1126/scisignal.2000397

By:

Kiel, Christina;
Serrano, Luis

Publication type:

Article

Tweeting in echo chambers? Analyzing Twitter discourse between American Jewish interest groups.

Published in:

Journal of Information Technology & Politics, 2021, v. 18, n. 2, p. 194, doi. 10.1080/19331681.2020.1838396

By:

Osterbur, Megan;
Kiel, Christina

Publication type:

Article

Protein design in biological networks: from manipulating the input to modifying the output.

Published in:

PEDS: Protein Engineering, Design & Selection, 2009, v. 22, n. 9, p. 537, doi. 10.1093/protein/gzp032

By:

Van der Sloot, Almer M.;
Kiel, Christina;
Serrano, Luis;
Stricher, Francois

Publication type:

Article

Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations.

Published in:

Molecular Systems Biology, 2014, v. 10, n. 5, p. n/a, doi. 10.1002/msb.20145092

By:

Kiel, Christina;
Serrano, Luis

Publication type:

Article

Structural and functional protein network analyses predict novel signaling functions for rhodopsin.

Published in:

Molecular Systems Biology, 2011, v. 7, n. 1, p. 1, doi. 10.1038/msb.2011.83

By:

Kiel, Christina;
Vogt, Andreas;
Campagna, Anne;
Chatr‐aryamontri, Andrew;
Swiatek‐de Lange, Magdalena;
Beer, Monika;
Bolz, Sylvia;
Mack, Andreas F;
Kinkl, Norbert;
Cesareni, Gianni;
Serrano, Luis;
Ueffing, Marius

Publication type:

Article

Epistatic interactions of genetic loci associated with age-related macular degeneration.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-92351-4

By:

Kiel, Christina;
Nebauer, Christoph A.;
Strunz, Tobias;
Stelzl, Simon;
Weber, Bernhard H. F.

Publication type:

Article

Dissecting the Calcium-Induced Differentiation of Human Primary Keratinocytes Stem Cells by Integrative and Structural Network Analyses.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pcbi.1004256

By:

Toufighi, Kiana;
Yang, Jae-Seong;
Luis, Nuno Miguel;
Aznar Benitah, Salvador;
Lehner, Ben;
Serrano, Luis;
Kiel, Christina

Publication type:

Article

Protein Conservation and Variation Suggest Mechanisms of Cell Type-Specific Modulation of Signaling Pathways.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 6, p. 1, doi. 10.1371/journal.pcbi.1003659

By:

Schaefer, Martin H.;
Yang, Jae-Seong;
Serrano, Luis;
Kiel, Christina

Publication type:

Article

Association Rate Constants of Ras-Effector Interactions Are Evolutionarily Conserved.

Published in:

PLoS Computational Biology, 2008, v. 4, n. 12, p. 1, doi. 10.1371/journal.pcbi.1000245

By:

Kiel, Christina;
Aydin, Dorothee;
Serrano, Luis

Publication type:

Article

Chicken dance (off): competing cultural diplomacy in the 2019 Eurovision Song Contest.

Published in:

International Journal of Cultural Policy, 2020, v. 26, n. 7, p. 973, doi. 10.1080/10286632.2020.1776269

By:

Kiel, Christina

Publication type:

Article

Seed sequence polymorphism rs2168518 and allele-specific target gene regulation of hsa-miR-4513.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 6, p. 875, doi. 10.1093/hmg/ddab292

By:

Kiel, Christina;
Strunz, Tobias;
Hasler, Daniele;
Meister, Gunter;
Grassmann, Felix;
Weber, Bernhard H F

Publication type:

Article

Reconstruction and analysis of a large-scale binary Ras-effector signaling network.

Published in:

Cell Communication & Signaling, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12964-022-00823-5

By:

Catozzi, Simona;
Ternet, Camille;
Gourrege, Alize;
Wynne, Kieran;
Oliviero, Giorgio;
Kiel, Christina

Publication type:

Article

A mega-analysis of expression quantitative trait loci in retinal tissue.

Published in:

PLoS Genetics, 2020, v. 16, n. 9, p. 1, doi. 10.1371/journal.pgen.1008934

By:

Strunz, Tobias;
Kiel, Christina;
Grassmann, Felix;
Ratnapriya, Rinki;
Kwicklis, Madeline;
Karlstetter, Marcus;
Fauser, Sascha;
Arend, Nicole;
Swaroop, Anand;
Langmann, Thomas;
Wolf, Armin;
Weber, Bernhard H. F.

Publication type:

Article

Predicted 'wiring landscape' of Ras-effector interactions in 29 human tissues.

Published in:

NPJ Systems Biology & Applications, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41540-021-00170-0

By:

Catozzi, Simona;
Halasz, Melinda;
Kiel, Christina

Publication type:

Article

Signaling pathways in intestinal homeostasis and colorectal cancer: KRAS at centre stage.

Published in:

2021

By:

Ternet, Camille;
Kiel, Christina

Publication type:

Literature Review

Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 12, p. 2147, doi. 10.1128/MCB.00914-13

By:

Piccoli, Giovanni;
Onofri, Franco;
Cirnaru, Maria Daniela;
Kaiser, Christoph J. O.;
Jagtap, Pravinkumar;
Kastenmüller, Andreas;
Pischedda, Francesca;
Marte, Antonella;
von Zweydorf, Felix;
Vogt, Andreas;
Giesert, Florian;
Lifeng Pan;
Antonucci, Flavia;
Kiel, Christina;
Mingjie Zhang;
Weinkauf, Sevil;
Sattler, Michael;
Sala, Carlo;
Matteoli, Michela;
Ueffing, Marius

Publication type:

Article

Disease–Gene Networks of Skin Pigmentation Disorders and Reconstruction of Protein–Protein Interaction Networks.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 1, p. 13, doi. 10.3390/bioengineering10010013

By:

D'Arcy, Cian;
Bass, Olivia;
Junk, Philipp;
Sevrin, Thomas;
Oliviero, Giorgio;
Wynne, Kieran;
Halasz, Melinda;
Kiel, Christina

Publication type:

Article

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-58510-9

By:

Strunz, Tobias;
Lauwen, Susette;
Kiel, Christina;
International AMD Genomics Consortium (IAMDGC);
Fritsche, Lars G.;
Igl, Wilmar;
Bailey, Jessica N. Cooke;
Grassmann, Felix;
Sengupta, Sebanti;
Bragg-Gresham, Jennifer L.;
Burdon, Kathryn P.;
Hebbring, Scott J.;
Wen, Cindy;
Gorski, Mathias;
Kim, Ivana K.;
Cho, David;
Zack, Donald;
Souied, Eric;
Scholl, Hendrik P. N.;
Bala, Elisa

Publication type:

Article

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits.

Published in:

Genome Medicine, 2017, v. 9, p. 1, doi. 10.1186/s13073-017-0418-0

By:

Grassmann, Felix;
Kiel, Christina;
Zimmermann, Martina E.;
Gorski, Mathias;
Grassmann, Veronika;
Stark, Klaus;
Heid, Iris M.;
Weber, Bernhard H. F.

Publication type:

Article

SAPIN: A framework for the structural analysis of protein interaction networks.

Published in:

Bioinformatics, 2012, v. 28, n. 22, p. 2998, doi. 10.1093/bioinformatics/bts539

By:

Yang, Jae-Seong;
Campagna, Anne;
Delgado, Javier;
Vanhee, Peter;
Serrano, Luis;
Kiel, Christina

Publication type:

Article

Prediction of Ras-effector interactions using position energy matrices.

Published in:

Bioinformatics, 2007, v. 23, n. 17, p. 2226, doi. 10.1093/bioinformatics/btm336

By:

Christina Kiel;
Luis Serrano

Publication type:

Article

A Circulating MicroRNA Profile in a Laser-Induced Mouse Model of Choroidal Neovascularization.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 8, p. 2689, doi. 10.3390/ijms21082689

By:

Kiel, Christina;
Berber, Patricia;
Karlstetter, Marcus;
Aslanidis, Alexander;
Strunz, Tobias;
Langmann, Thomas;
Grassmann, Felix;
Weber, Bernhard H.F.

Publication type:

Article

Phylogeographic and evolutionary history analyses of the warty crab Eriphia verrucosa (Decapoda, Brachyura, Eriphiidae) unveil genetic imprints of a late Pleistocene vicariant event across the Gibraltar Strait, erased by postglacial expansion and admixture among refugial lineages

Published in:

BMC Evolutionary Biology, 2019, v. 19, n. 1, p. 1, doi. 10.1186/s12862-019-1423-2

By:

Deli, Temim;
Kiel, Christina;
Schubart, Christoph D.

Publication type:

Article

HOMELETTE: a unified interface to homology modelling software.

Published in:

Bioinformatics, 2022, v. 38, n. 6, p. 1749, doi. 10.1093/bioinformatics/btab866

By:

Junk, Philipp;
Kiel, Christina

Publication type:

Article

TAPAS: tools to assist the targeted protein quantification of human alternative splice variants.

Published in:

Bioinformatics, 2014, v. 30, n. 20, p. 2989, doi. 10.1093/bioinformatics/btu428

By:

Yang, Jae-Seong;
Sabidó, Eduard;
Serrano, Luis;
Kiel, Christina

Publication type:

Article

A Comprehensive View of the β-Arrestinome.

Published in:

Frontiers in Endocrinology, 2017, v. 8, p. 1, doi. 10.3389/fendo.2017.00032

By:

Crépieux, Pascale;
Poupon, Anne;
Langonné-Gallay, Nathalie;
Reiter, Eric;
Delgado, Javier;
Schaefer, Martin H.;
Bourquard, Thomas;
Serrano, Luis;
Kiel, Christina

Publication type:

Article

Assessment of Novel Genome-Wide Significant Gene Loci and Lesion Growth in Geographic Atrophy Secondary to Age-Related Macular Degeneration.

Published in:

2019

By:

Grassmann, Felix;
Harsch, Sebastian;
Brandl, Caroline;
Kiel, Christina;
Nürnberg, Peter;
Toliat, Mohammad R.;
Fleckenstein, Monika;
Pfau, Maximilian;
Schmitz-Valckenberg, Steffen;
Holz, Frank G.;
Chew, Emily Y.;
Swaroop, Anand;
Ratnapriya, Rinki;
Klein, Michael L.;
Mulyukov, Zufar;
Zamiri, Parisa;
Weber, Bernhard H. F.

Publication type:

journal article

Simple and complex retinal dystrophies are associated with profoundly different disease networks.

Published in:

Scientific Reports, 2017, p. 41835, doi. 10.1038/srep41835

By:

Kiel, Christina;
Lastrucci, Claire;
Luthert, Philip J.;
Serrano, Luis

Publication type:

Article

Tuneable endogenous mammalian target complementation via multiplexed plasmid-based recombineering.

Published in:

Scientific Reports, 2015, p. 17432, doi. 10.1038/srep17432

By:

Beltran-Sastre, Violeta;
Benisty, Hannah;
Burnier, Julia;
Berger, Imre;
Serrano, Luis;
Kiel, Christina

Publication type:

Article

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease.

Published in:

BMC Medical Genomics, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s12920-020-00760-7

By:

Winkler, Thomas W.;
Grassmann, Felix;
Brandl, Caroline;
Kiel, Christina;
Günther, Felix;
Strunz, Tobias;
Weidner, Lorraine;
Zimmermann, Martina E.;
Korb, Christina A.;
Poplawski, Alicia;
Schuster, Alexander K.;
Müller-Nurasyid, Martina;
Peters, Annette;
Rauscher, Franziska G.;
Elze, Tobias;
Horn, Katrin;
Scholz, Markus;
Cañadas-Garre, Marisa;
McKnight, Amy Jayne;
Quinn, Nicola

Publication type:

Article

Diagnostic testing in the genetically complex age-related macular degeneration.

Published in:

Medizinische Genetik, 2025, v. 37, n. 1, p. 27, doi. 10.1515/medgen-2024-2064

By:

Kiel, Christina;
Weber, Bernhard H. F.

Publication type:

Article

An Eye on Age-Related Macular Degeneration: The Role of MicroRNAs in Disease Pathology.

Published in:

Molecular Diagnosis & Therapy, 2017, v. 21, n. 1, p. 31, doi. 10.1007/s40291-016-0234-z

By:

Berber, Patricia;
Grassmann, Felix;
Kiel, Christina;
Weber, Bernhard

Publication type:

Article

The yin–yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.12814

By:

Kiel, Christina;
Benisty, Hannah;
Lloréns-Rico, Veronica;
Serrano, Luis

Publication type:

Article

Vitronectin and Its Interaction with PAI-1 Suggests a Functional Link to Vascular Changes in AMD Pathobiology.

Published in:

Cells (2073-4409), 2022, v. 11, n. 11, p. 1766, doi. 10.3390/cells11111766

By:

Biasella, Fabiola;
Strunz, Tobias;
Kiel, Christina;
Weber, Bernhard H. F.;
Friedrich, Ulrike

Publication type:

Article

Assigning Co-Regulated Human Genes and Regulatory Gene Clusters.

Published in:

Cells (2073-4409), 2021, v. 10, n. 9, p. 2395, doi. 10.3390/cells10092395

By:

Strunz, Tobias;
Kellner, Martin;
Kiel, Christina;
Weber, Bernhard H. F.

Publication type:

Article

Learning from Fifteen Years of Genome-Wide Association Studies in Age-Related Macular Degeneration.

Published in:

Cells (2073-4409), 2020, v. 9, n. 10, p. 2267, doi. 10.3390/cells9102267

By:

Strunz, Tobias;
Kiel, Christina;
Sauerbeck, Bastian L.;
Weber, Bernhard H. F.

Publication type:

Article

Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD).

Published in:

Cells (2073-4409), 2020, v. 9, n. 10, p. 2257, doi. 10.3390/cells9102257

By:

Kiel, Christina;
Strunz, Tobias;
Grassmann, Felix;
Weber, Bernhard H. F.

Publication type:

Article

Shaping dots and lines: Adding modularity into protein interaction networks using structural information

Published in:

FEBS Letters, 2008, v. 582, n. 8, p. 1231, doi. 10.1016/j.febslet.2008.02.019

By:

Campagna, Anne;
Serrano, Luis;
Kiel, Christina

Publication type:

Article

Cell Adhesion Molecules in Normal Skin and Melanoma.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 8, p. 1213, doi. 10.3390/biom11081213

By:

D'Arcy, Cian;
Kiel, Christina

Publication type:

Article

The Ins and Outs of RAS Effector Complexes.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 2, p. 236, doi. 10.3390/biom11020236

By:

Kiel, Christina;
Matallanas, David;
Kolch, Walter

Publication type:

Article

A hegemon fighting for equal rights: the dominant role of COC Nederland in the LGBT transnational advocacy network.

Published in:

Global Networks, 2017, v. 17, n. 2, p. 234, doi. 10.1111/glob.12126

By:

OSTERBUR, MEGAN;
KIEL, CHRISTINA

Publication type:

Article

"Energetics of the outer retina II: Calculation of a spatio-temporal energy budget in retinal pigment epithelium and photoreceptor cells based on quantification of cellular processes".

Published in:

PLoS ONE, 2025, v. 20, n. 1, p. 1, doi. 10.1371/journal.pone.0311169

By:

Kiel, Christina;
Prins, Stella;
Foss, Alexander J. E.;
Luthert, Philip J.

Publication type:

Article

"Energetics of the outer retina I: Estimates of nutrient exchange and ATP generation".

Published in:

PLoS ONE, 2024, v. 19, n. 12, p. 1, doi. 10.1371/journal.pone.0312260

By:

Prins, Stella;
Kiel, Christina;
Foss, Alexander J. E.;
Zouache, Moussa A.;
Luthert, Philip J.

Publication type:

Article

Systems level expression correlation of Ras GTPase regulators.

Published in:

Cell Communication & Signaling, 2018, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12964-018-0256-8

By:

Besray Unal, E.;
Kiel, Christina;
Benisty, Hannah;
Campbell, Andrew;
Pickering, Karen;
Blüthgen, Nils;
Sansom, Owen J.;
Serrano, Luis

Publication type:

Article