Works by Kiaei, Mahmoud

Results: 31

RNA-Seq Analysis of Spinal Cord Tissues from hPFN1G118V Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31132-y

By:

Barham, Caroline;
Fil, Daniel;
Byrum, Stephanie D.;
Rahmatallah, Yasir;
Glazko, Galina;
Kiaei, Mahmoud

Publication type:

Article

ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31199-7

By:

Kiaei, Mahmoud;
Balasubramaniam, Meenakshisundaram;
Govind Kumar, Vivek;
Shmookler Reis, Robert J.;
Moradi, Mahmoud;
Varughese, Kottayil I.

Publication type:

Article

Anticancer effect of calycopterin via PI3K/Akt and MAPK signaling pathways, ROS-mediated pathway and mitochondrial dysfunction in hepatoblastoma cancer (HepG2) cells.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 397, n. 1/2, p. 17, doi. 10.1007/s11010-014-2166-4

By:

Esmaeili, Mohammad;
Farimani, Mahdi;
Kiaei, Mahmoud

Publication type:

Article

Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription.

Published in:

PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005757

By:

Lichuan Yang;
Calingasan, Noel Y.;
Thomas, Bobby;
Chaturvedi, Rajnish K.;
Kiaei, Mahmoud;
Wille, Elizabeth J.;
Liby, Karen T.;
Williams, Charlotte;
Royce, Darlene;
Risingsong, Renee;
Musiek, Eric S.;
Morrow, Jason D.;
Sporn, Michael;
Beal, M. Flint

Publication type:

Article

Thalidomide and Lenalidomide Extend Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 9, p. 2467, doi. 10.1523/JNEUROSCI.5253-05.2006

By:

Kiaei, Mahmoud;
Petri, Susanne;
Kipiani, Khatuna;
Gardian, Gabrielle;
Dong-Kug Choi;
Junyu Chen;
Calingasan, Noel Y.;
Schafer, Peter;
Muller, George W.;
Stewart, Charles;
Hensley, Kenneth;
Beal, M. Flint

Publication type:

Article

Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 36, p. 7945, doi. 10.1523/JNEUROSCI.2000-04.2004

By:

Kiaei, Mahmoud;
Bush, Ashley I.;
Morrison, Brett M.;
Morrison, John H.;
Cherny, Robert A.;
Volitakis, Irene;
Beal, M. Flint;
Gordon, Jon W.

Publication type:

Article

Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 2, p. 317, doi. 10.1093/hmg/ddv477

By:

Esmaeili, Mohammad A.;
Yadav, Shilpi;
Gupta, Ravi Kr.;
Waggoner, Garrett R.;
Deloach, Abigail;
Calingasan, Noel Y.;
Beal, M. Flint;
Kiaei, Mahmoud

Publication type:

Article

Nrf2/ARE Signaling Pathway: Key Mediator in Oxidative Stress and Potential Therapeutic Target in ALS.

Published in:

Neurology Research International, 2012, p. 1, doi. 10.1155/2012/878030

By:

Petri, Susanne;
Körner, Sonja;
Kiaei, Mahmoud

Publication type:

Article

Amyotrophic Lateral Sclerosis and Novel Therapeutic Strategies.

Published in:

Neurology Research International, 2012, p. 1, doi. 10.1155/2012/798028

By:

Morrison, Brett;
Hensley, Kenneth;
Pioro, Erik P.;
Petri, Susanne;
Kiaei, Mahmoud

Publication type:

Article

Alginate oligosaccharide protects against H2O2 -induced endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death

Published in:

2011

By:

Khodagholi, Fariba;
Ashabi, Ghorbangol;
Tusi, Solaleh Khoramian;
Khalaj, Leila;
Kiaei, Mahmoud

Publication type:

Abstract

Molecular Dynamics Guided Design of Tocoflexol: A New Radioprotectant Tocotrienol with Enhanced Bioavailability.

Published in:

Drug Development Research, 2014, v. 75, n. 1, p. 10, doi. 10.1002/ddr.21162

By:

Compadre, Cesar M.;
Singh, Awantika;
Thakkar, Shraddha;
Zheng, Guangrong;
Breen, Philip J.;
Ghosh, Sanchita;
Kiaei, Mahmoud;
Boerma, Marjan;
Varughese, Kottayil I.;
Hauer ‐ Jensen, Martin

Publication type:

Article

A systematic review of emerging technologies to enhance the treatment of ovarian cancer.

Published in:

Pharmaceutical Development & Technology, 2023, v. 28, n. 7, p. 660, doi. 10.1080/10837450.2023.2233588

By:

Sepahi, Samaneh;
Kiaei, Lily;
Kiaei, Mahmoud;
Ghorani-Azam, Adel

Publication type:

Article

In silico studies reveal structural deviations of mutant profilin-1 and interaction with riluzole and edaravone in amyotrophic lateral sclerosis.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-86211-4

By:

Sadr, Ahmad Shahir;
Eslahchi, Changiz;
Ghassempour, Alireza;
Kiaei, Mahmoud

Publication type:

Article

Impaired PGC-1α function in muscle in Huntington's disease.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 16, p. 3048, doi. 10.1093/hmg/ddp243

By:

Chaturvedi, Rajnish K.;
Adhihetty, Peter;
Shukla, Shubha;
Hennessy, Thomas;
Calingasan, Noel;
Yang, Lichuan;
Starkov, Anatoly;
Kiaei, Mahmoud;
Cannella, Milena;
Sassone, Jenny;
Ciammola, Andrea;
Squitieri, Fernando;
Beal, M. Flint

Publication type:

Article

Mutant Profilin1 Aggregation in Amyotrophic Lateral Sclerosis: An in Vivo Biochemical Analysis.

Published in:

Basic & Clinical Neuroscience, 2021, v. 12, n. 2, p. 213, doi. 10.32598/bcn.12.2.1631.1

By:

Nekouei, Mina;
Aliahmadi, Atousa;
Kiaei, Mahmoud;
Ghassempour, Ali Reza

Publication type:

Article

New Hopes and Challenges for Treatment of Neurodegenerative Disorders: Great Opportunities for Young Neuroscientists.

Published in:

2013

By:

Kiaei, Mahmoud

Publication type:

Editorial

Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis.

Published in:

Journal of Neurochemistry, 2006, v. 98, n. 4, p. 1141, doi. 10.1111/j.1471-4159.2006.04018.x

By:

Petri, Susanne;
Kiaei, Mahmoud;
Damiano, Maria;
Hiller, Andrew;
Wille, Elizabeth;
Manfredi, Giovanni;
Calingasan, Noel Y.;
Szeto, Hazel H.;
Beal, M. Flint

Publication type:

Article

Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice.

Published in:

Journal of Neurochemistry, 2006, v. 96, n. 5, p. 1349, doi. 10.1111/j.1471-4159.2006.03619.x

By:

Damiano, Maria;
Starkov, Anatoly A.;
Petri, Susanne;
Kipiani, Kathuna;
Kiaei, Mahmoud;
Mattiazzi, Marina;
Flint Beal, M.;
Manfredi, Giovanni

Publication type:

Article

Integrative role of cPLA2 with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis.

Published in:

Journal of Neurochemistry, 2005, v. 93, n. 2, p. 403, doi. 10.1111/j.1471-4159.2005.03024.x

By:

Kiaei, Mahmoud;
Kipiani, Khatuna;
Petri, Susanne;
Dong-Kug Choi;
Junyu Chen;
Calingasan, Noel Y.;
Beal, M. Flint

Publication type:

Article

Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis.

Published in:

Journal of Neurochemistry, 2003, v. 85, n. 1, p. 142, doi. 10.1046/j.1471-4159.2003.01639.x

By:

Wu, Annie S.;
Kiaei, Mahmoud;
Aguirre, Norberto;
Crow, John P.;
Calingasan, Noel Y.;
Browne, Susan E.;
Beal, M. Flint

Publication type:

Article

The lipophilic metal chelators DP-109 and DP-460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis.

Published in:

Journal of Neurochemistry, 2007, v. 102, n. 3, p. 991, doi. 10.1111/j.1471-4159.2007.04604.x

By:

Petri, Susanne;
Calingasan, Noel Y.;
Alsaied, Osama A.;
Wille, Elizabeth;
Kiaei, Mahmoud;
Friedman, Jonathan E.;
Baranova, Oxana;
Chavez, Juan C.;
Beal, M. Flint

Publication type:

Article

In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28381-x

By:

Ganne, Akshatha;
Balasubramaniam, Meenakshisundaram;
Ayyadevara, Haarika;
Kiaei, Lily;
Shmookler Reis, Robert J.;
Varughese, Kottayil I.;
Kiaei, Mahmoud

Publication type:

Article

Peroxisome Proliferator-Activated Receptor-γ in Amyotrophic Lateral Sclerosis and Huntington's Disease.

Published in:

PPAR Research, 2008, p. 1, doi. 10.1155/2008/418765

By:

Kiaei, Mahmoud

Publication type:

Article

RNA as a source of biomarkers for amyotrophic lateral sclerosis.

Published in:

2022

By:

Kiaei, Lily;
Kiaei, Mahmoud

Publication type:

Literature Review

Correction to: RNA as a Source of Biomarkers for Amyotrophic Lateral Sclerosis.

Published in:

2022

By:

Kiaei, Lily;
Kiaei, Mahmoud

Publication type:

Correction Notice

Detection of structural and conformational changes in ALS-causing mutant profilin-1 with hydrogen/deuterium exchange mass spectrometry and bioinformatics techniques.

Published in:

Metabolic Brain Disease, 2022, v. 37, n. 1, p. 229, doi. 10.1007/s11011-021-00763-y

By:

Sadr, Ahmad Shahir;
Abdollahpour, Zahra;
Aliahmadi, Atousa;
Eslahchi, Changiz;
Nekouei, Mina;
Kiaei, Lily;
Kiaei, Mahmoud;
Ghassempour, Alireza

Publication type:

Article

Changes in biophysical characteristics of PFN1 due to mutation causing amyotrophic lateral sclerosis.

Published in:

Metabolic Brain Disease, 2018, v. 33, n. 6, p. 1975, doi. 10.1007/s11011-018-0305-4

By:

Nekouei, Mina;
Ghezellou, Parviz;
Aliahmadi, Atousa;
Arjmand, Sareh;
Kiaei, Mahmoud;
Ghassempour, Alireza

Publication type:

Article

Profilin1 biology and its mutation, actin(g) in disease.

Published in:

Cellular & Molecular Life Sciences, 2017, v. 74, n. 6, p. 967, doi. 10.1007/s00018-016-2372-1

By:

Alkam, Duah;
Feldman, Ezra;
Singh, Awantika;
Kiaei, Mahmoud

Publication type:

Article

Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy.

Published in:

Cellular & Molecular Life Sciences, 2013, v. 70, n. 24, p. 4681, doi. 10.1007/s00018-013-1409-y

By:

Digaleh, Hadi;
Kiaei, Mahmoud;
Khodagholi, Fariba

Publication type:

Article

Premature death of TDP-43 ( A315 T) transgenic mice due to gastrointestinal complications prior to development of full neurological symptoms of amyotrophic lateral sclerosis.

Published in:

International Journal of Experimental Pathology, 2013, v. 94, n. 1, p. 56, doi. 10.1111/iep.12006

By:

Esmaeili, Mohammad A.;
Panahi, Marzieh;
Yadav, Shilpi;
Hennings, Leah;
Kiaei, Mahmoud

Publication type:

Article

Celastrol Blocks Neuronal Cell Death and Extends Life in Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Neurodegenerative Diseases, 2005, v. 2, n. 5, p. 246, doi. 10.1159/000090364

By:

Kiaei, Mahmoud;
Kipiani, Khatuna;
Petri, Susanne;
Junyu Chen;
Calingasan, Noel Y.;
Beal, M. Flint

Publication type:

Article

Works by Kiaei, Mahmoud

RNA-Seq Analysis of Spinal Cord Tissues from hPFN1<sup>G118V</sup> Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease.

ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation.

Anticancer effect of calycopterin via PI3K/Akt and MAPK signaling pathways, ROS-mediated pathway and mitochondrial dysfunction in hepatoblastoma cancer (HepG2) cells.

Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription.

Thalidomide and Lenalidomide Extend Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.

Nrf2/ARE Signaling Pathway: Key Mediator in Oxidative Stress and Potential Therapeutic Target in ALS.

Amyotrophic Lateral Sclerosis and Novel Therapeutic Strategies.

Alginate oligosaccharide protects against H2O2 -induced endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death

Molecular Dynamics Guided Design of Tocoflexol: A New Radioprotectant Tocotrienol with Enhanced Bioavailability.

A systematic review of emerging technologies to enhance the treatment of ovarian cancer.

In silico studies reveal structural deviations of mutant profilin-1 and interaction with riluzole and edaravone in amyotrophic lateral sclerosis.

Impaired PGC-1α function in muscle in Huntington's disease.

Mutant Profilin1 Aggregation in Amyotrophic Lateral Sclerosis: An in Vivo Biochemical Analysis.

New Hopes and Challenges for Treatment of Neurodegenerative Disorders: Great Opportunities for Young Neuroscientists.

Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis.

Neural mitochondrial Ca<sup>2+</sup> capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice.

Integrative role of cPLA<sub>2</sub> with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis.

Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis.

The lipophilic metal chelators DP-109 and DP-460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis.

In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration.

Peroxisome Proliferator-Activated Receptor-γ in Amyotrophic Lateral Sclerosis and Huntington's Disease.

RNA as a source of biomarkers for amyotrophic lateral sclerosis.

Correction to: RNA as a Source of Biomarkers for Amyotrophic Lateral Sclerosis.

Detection of structural and conformational changes in ALS-causing mutant profilin-1 with hydrogen/deuterium exchange mass spectrometry and bioinformatics techniques.

Changes in biophysical characteristics of PFN1 due to mutation causing amyotrophic lateral sclerosis.

Profilin1 biology and its mutation, actin(g) in disease.

Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy.

Premature death of TDP-43 ( A315 T) transgenic mice due to gastrointestinal complications prior to development of full neurological symptoms of amyotrophic lateral sclerosis.

Celastrol Blocks Neuronal Cell Death and Extends Life in Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.