Works by Khor, Chiea Chuen

Results: 111

Evaluation of plasma brain-derived neurotrophic factor levels and self-perceived cognitive impairment post-chemotherapy: a longitudinal study.

Published in:

2017

By:

Terence Ng;
Ying Yun Lee;
Jung-woo Chae;
Angie Hui Ling Yeo;
Maung Shwe;
Yan Xiang Gan;
Ng, Raymond C. H.;
Pat Pak Yan Chu;
Chiea Chuen Khor;
Han Kiat Ho;
Alexandre Chan;
Ng, Terence;
Lee, Ying Yun;
Chae, Jung-Woo;
Yeo, Angie Hui Ling;
Shwe, Maung;
Gan, Yan Xiang;
Chu, Pat Pak Yan;
Khor, Chiea Chuen;
Ho, Han Kiat

Publication type:

journal article

Genetic variants of MICB and PLCE1 and associations with the laboratory features of dengue.

Published in:

2017

By:

Whitehorn, James;
Duong Thi Hue Kien;
Nguyen Than Ha Quyen;
Wills, Bridget;
Nguyen Van Vinh Chau;
Dong Thi Hoai Tam;
Nguyen Minh Tuan;
Jaenisch, Thomas;
Hibberd, Martin;
Chiea Chuen Khor;
Simmons, Cameron P.;
Kien, Duong Thi Hue;
Quyen, Nguyen Than Ha;
Van Vinh Chau, Nguyen;
Tam, Dong Thi Hoai;
Tuan, Nguyen Minh;
Khor, Chiea Chuen

Publication type:

journal article

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology.

Published in:

Genetic Epidemiology, 2015, v. 39, n. 3, p. 207, doi. 10.1002/gepi.21886

By:

Springelkamp, Henriët;
Mishra, Aniket;
Hysi, Pirro G.;
Gharahkhani, Puya;
Höhn, René;
Khor, Chiea ‐ Chuen;
Cooke Bailey, Jessica N.;
Luo, Xiaoyan;
Ramdas, Wishal D.;
Vithana, Eranga;
Koh, Victor;
Yazar, Seyhan;
Xu, Liang;
Forward, Hannah;
Kearns, Lisa S.;
Amin, Najaf;
Iglesias, Adriana I.;
Sim, Kar ‐ Seng;
Leeuwen, Elisabeth M.;
Demirkan, Ayse

Publication type:

Article

Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.82608

By:

Peh Joo Ho;
Tan, Iain BeeHuat;
Chong, Dawn Qingqing;
Chiea Chuen Khor;
Jian-Min Yuan;
Woon-Puay Koh;
Dorajoo, Rajkumar;
Jingmei Li

Publication type:

Article

Utility of genetic and non-genetic risk factors in predicting coronary heart disease in Singaporean Chinese.

Published in:

European Journal of Preventive Cardiology, 2017, v. 24, n. 1, p. 153, doi. 10.1177/2047487316676609

By:

Chang, Xuling;
Salim, Agus;
Dorajoo, Rajkumar;
Han, Yi;
Khor, Chiea-Chuen;
van Dam, Rob M;
Yuan, Jian-Min;
Koh, Woon-Puay;
Liu, Jianjun;
Goh, Daniel YT;
Wang, Xu;
Teo, Yik-Ying;
Friedlander, Yechiel;
Heng, Chew-Kiat

Publication type:

Article

Shortened Telomere Length in Sputum Cells of Bronchiectasis Patients is Associated with Dysfunctional Inflammatory Pathways.

Published in:

Lung (0341-2040), 2022, v. 200, n. 3, p. 401, doi. 10.1007/s00408-022-00535-0

By:

Lim, Hui Fang;
Tan, Nadia Suray;
Dehghan, Roghayeh;
Shen, Meixin;
Liew, Mei Fong;
Bee, Stella Wei Lee;
Sia, Yee Yen;
Liu, Jianjun;
Khor, Chiea Chuen;
Kwok, Immanuel;
Ng, Lai Guan;
Angeli, Veronique;
Dorajoo, Rajkumar

Publication type:

Article

Machine learning using genetic and clinical data identifies a signature that robustly predicts methotrexate response in rheumatoid arthritis.

Published in:

Rheumatology, 2022, v. 61, n. 10, p. 4175, doi. 10.1093/rheumatology/keac032

By:

Lim, Lee Jin;
Lim, Ashley J W;
Ooi, Brandon N S;
Tan, Justina Wei Lynn;
Koh, Ee Tzun;
Group, TTSH Rheumatoid Arthritis Study;
Chong, Samuel S.;
Khor, Chiea Chuen;
Tucker-Kellogg, Lisa;
Lee, Caroline G.;
Leong, Khai Pang

Publication type:

Article

Identification of a shared genetic risk locus for Kawasaki disease and immunoglobulin A vasculitis by a cross-phenotype meta-analysis.

Published in:

Rheumatology, 2022, v. 61, n. 3, p. 1204, doi. 10.1093/rheumatology/keab443

By:

Carmona, Elio G;
García-Giménez, Jose A;
López-Mejías, Raquel;
Khor, Chiea Chuen;
Lee, Jong-Keuk;
Taskiran, Ekim;
Ozen, Seza;
Hocevar, Alojzija;
Liu, Lili;
Gorenjak, Mario;
Potočnik, Uroš;
Kiryluk, Krzysztof;
Ortego-Centeno, Norberto;
Cid, María C;
Hernández-Rodríguez, José;
Castañeda, Santos;
González-Gay, Miguel A;
Burgner, David;
Martín, Javier;
Márquez, Ana

Publication type:

Article

Cross‐Ancestry Genome‐Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 3, p. 712, doi. 10.1002/cpt.2846

By:

Khor, Chiea Chuen;
Winter, Stefan;
Sutiman, Natalia;
Mürdter, Thomas E.;
Chen, Sylvia;
Lim, Joanne Siok Liu;
Li, Zheng;
Li, Jingmei;
Sim, Kar Seng;
Ganchev, Boian;
Eccles, Diana;
Eccles, Bryony;
Tapper, William;
Zgheib, Nathalie K.;
Tfayli, Arafat;
Ng, Raymond Chee Hui;
Yap, Yoon Sim;
Lim, Elaine;
Wong, Mabel;
Wong, Nan Soon

Publication type:

Article

Plasma endothelin-1 and single nucleotide polymorphisms of endothelin-1 and endothelin type A receptor genes as risk factors for normal tension glaucoma.

Published in:

Molecular Vision, 2016, v. 22, p. 1

By:

Kosior-Jarecka, Ewa;
Wróbel-Dudzińska, Dominika;
Łukasik, Urszula;
Aung, Tin;
Khor, Chiea Chuen;
Kocki, Janusz;
Żarnowski, Tomasz

Publication type:

Article

Polygenic Risk Scores in a Prospective Parkinson's Disease Cohort.

Published in:

Movement Disorders, 2021, v. 36, n. 12, p. 2936, doi. 10.1002/mds.28761

By:

Sia, Ming‐Wei;
Foo, Jia‐Nee;
Saffari, Seyed‐Ehsan;
Wong, Aidan Sheng‐Yong;
Khor, Chiea‐Chuen;
Yuan, Jian‐Min;
Tan, Eng‐King;
Koh, Woon‐Puay;
Tan, Louis Chew‐Seng

Publication type:

Article

Linking a genome-wide association study signal to a LRRK2 coding variant in Parkinson's disease.

Published in:

2016

By:

Foo, Jia Nee;
Chung, Sun Ju;
Tan, Louis C.;
Liany, Herty;
Ryu, Ho‐Sung;
Hong, Myunghee;
Koh, Tat Hung;
Irwan, Ishak D.;
Au, Wing‐Lok;
Prakash, Kumar‐M.;
Aung, Tin;
Cheng, Ching‐Yu;
Chong, Siow‐Ann;
Khor, Chiea Chuen;
Lee, Jimmy;
Tai, E‐Shyong;
Vithana, Eranga N.;
Wong, Tien‐Yin;
Song, Kyuyoung;
Liu, Jianjun

Publication type:

journal article

Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-01421-2

By:

Yonova-Doing, Ekaterina;
Zhao, Wanting;
Igo, Robert P.;
Wang, Chaolong;
Sundaresan, Periasamy;
Lee, Kristine E.;
Jun, Gyungah R.;
Alves, Alexessander Couto;
Chai, Xiaoran;
Chan, Anita S. Y.;
Lee, Mei Chin;
Fong, Allan;
Tan, Ava G.;
Khor, Chiea Chuen;
Chew, Emily Y.;
Hysi, Pirro G.;
Fan, Qiao;
Chua, Jacqueline;
Chung, Jaeyoon;
Liao, Jiemin

Publication type:

Article

Keratoconus-susceptibility gene identification by corneal thickness genome-wide association study and artificial intelligence IBM Watson.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-01137-3

By:

Hosoda, Yoshikatsu;
Miyake, Masahiro;
Meguro, Akira;
Tabara, Yasuharu;
Iwai, Sachiko;
Ueda-Arakawa, Naoko;
Nakano, Eri;
Mori, Yuki;
Yoshikawa, Munemitsu;
Nakanishi, Hideo;
Khor, Chiea-Chuen;
Saw, Seang-Mei;
Yamada, Ryo;
Matsuda, Fumihiko;
Cheng, Ching-Yu;
Mizuki, Nobuhisa;
Tsujikawa, Akitaka;
Yamashiro, Kenji;
Kawaguchi, Takahisa;
Setoh, Kazuya

Publication type:

Article

Exploring RNF213 in Ischemic Stroke and Moyamoya Disease: From Cellular Models to Clinical Insights.

Published in:

Biomedicines, 2025, v. 13, n. 1, p. 17, doi. 10.3390/biomedicines13010017

By:

Tan, Benjamin Y. Q.;
Kok, Charlene H. P.;
Ng, Megan B. J.;
Loong, Shaun;
Jou, Eric;
Yeo, Leonard L. L.;
Han, Weiping;
Anderson, Christopher D.;
Khor, Chiea Chuen;
Lai, Poh San

Publication type:

Article

Performance of Polygenic Risk Scores for Primary Open-Angle Glaucoma in Populations of African Descent.

Published in:

JAMA Ophthalmology, 2025, v. 143, n. 1, p. 7, doi. 10.1001/jamaophthalmol.2024.4784

By:

Chang-Wolf, Jennifer M.;
Kinzy, Tyler G.;
Driessen, Sjoerd J.;
Cruz, Lauren A.;
Iyengar, Sudha K.;
Peachey, Neal S.;
Aung, Tin;
Khor, Chiea Chuen;
Williams, Susan E.;
Ramsay, Michele;
Olawoye, Olusola;
Ashaye, Adeyinka;
Klaver, Caroline C. W.;
Hauser, Michael A.;
Thiadens, Alberta A. H. J.;
Cooke Bailey, Jessica N.;
Bonnemaijer, Pieter W. M.

Publication type:

Article

LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 22, p. 11189, doi. 10.1093/nar/gks918

By:

Wilm, Andreas;
Aw, Pauline Poh Kim;
Bertrand, Denis;
Yeo, Grace Hui Ting;
Ong, Swee Hoe;
Wong, Chang Hua;
Khor, Chiea Chuen;
Petric, Rosemary;
Hibberd, Martin Lloyd;
Nagarajan, Niranjan

Publication type:

Article

A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations.

Published in:

European Journal of Human Genetics, 2012, v. 20, n. 4, p. 469, doi. 10.1038/ejhg.2011.219

By:

Wang, Xu;
Liu, Xuanyao;
Sim, Xueling;
Xu, Haiyan;
Khor, Chiea-Chuen;
Ong, Rick Twee-Hee;
Tay, Wan-Ting;
Suo, Chen;
Poh, Wan-Ting;
Ng, Daniel Peng-Keat;
Liu, Jianjun;
Aung, Tin;
Chia, Kee-Seng;
Wong, Tien-Yin;
Tai, E-Shyong;
Teo, Yik-Ying

Publication type:

Article

Natural positive selection and north-south genetic diversity in East Asia.

Published in:

European Journal of Human Genetics, 2012, v. 20, n. 1, p. 102, doi. 10.1038/ejhg.2011.139

By:

Suo, Chen;
Xu, Haiyan;
Khor, Chiea-Chuen;
Ong, Rick TH;
Sim, Xueling;
Chen, Jieming;
Tay, Wan-Ting;
Sim, Kar-Seng;
Zeng, Yi-Xin;
Zhang, Xuejun;
Liu, Jianjun;
Tai, E-Shyong;
Wong, Tien-Yin;
Chia, Kee-Seng;
Teo, Yik-Ying

Publication type:

Article

Correction to: Novel mutation G324C in WNT1 mapped in a large Pakistani family with severe recessively inherited Osteogenesis Imperfecta.

Published in:

2019

By:

Kausar, Mehran;
Siddiqi, Saima;
Yaqoob, Muhammad;
Mansoor, Sajid;
Makitie, Outi;
Mir, Asif;
Khor, Chiea Chuen;
Foo, Jia Nee;
Anees, Mariam

Publication type:

Correction Notice

Interaction Between Peroxisome Proliferator Activated Receptor δ and Epithelial Membrane Protein 2 Polymorphisms Influences HDL-C Levels in the Chinese Population.

Published in:

Annals of Human Genetics, 2016, v. 80, n. 5, p. 282, doi. 10.1111/ahg.12164

By:

Ke, Tingjing;
Dorajoo, Rajkumar;
Han, Yi;
Khor, Chiea‐Chuen;
Dam, Rob M.;
Yuan, Jian‐Min;
Koh, Woon‐Puay;
Liu, Jianjun;
Teo, Yik Ying;
Goh, Daniel Y.T.;
Tai, E Shyong;
Wong, Tien Yin;
Cheng, Ching‐Yu;
Friedlander, Yechiel;
Heng, Chew‐Kiat

Publication type:

Article

MUC5AC Genetic Variation Is Associated With Tuberculous Meningitis Cerebral Spinal Fluid Cytokine Responses and Mortality.

Published in:

Journal of Infectious Diseases, 2023, v. 228, n. 3, p. 343, doi. 10.1093/infdis/jiad050

By:

Sabo, Michelle C;
Thuong, Nguyen T T;
Chang, Xuling;
Ardiansyah, Edwin;
Tram, Trinh T B;
Hai, Hoang T;
Nghia, Ho D T;
Bang, Nguyen D;
Dian, Sofiati;
Ganiem, A Rizal;
Shaporifar, Shima;
Kumar, Vinod;
Li, Zheng;
Hibberd, Martin;
Khor, Chiea Chuen;
Thwaites, Guy E;
Heemskerk, Dorothee;
Laarhoven, Arjan van;
Crevel, Reinout van;
Dunstan, Sarah J

Publication type:

Article

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma.

Published in:

Nature Genetics, 2012, v. 44, n. 10, p. 1142, doi. 10.1038/ng.2390

By:

Vithana, Eranga N;
Khor, Chiea-Chuen;
Qiao, Chunyan;
Nongpiur, Monisha E;
George, Ronnie;
Chen, Li-Jia;
Do, Tan;
Abu-Amero, Khaled;
Huang, Chor Kai;
Low, Sancy;
Tajudin, Liza-Sharmini A;
Perera, Shamira A;
Cheng, Ching-Yu;
Xu, Liang;
Jia, Hongyan;
Ho, Ching-Lin;
Sim, Kar Seng;
Wu, Ren-Yi;
Tham, Clement C Y;
Chew, Paul T K

Publication type:

Article

Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease.

Published in:

Nature Genetics, 2011, v. 43, n. 12, p. 1241, doi. 10.1038/ng.981

By:

Khor, Chiea Chuen;
Davila, Sonia;
Breunis, Willemijn B;
Lee, Yi-Ching;
Shimizu, Chisato;
Wright, Victoria J;
Yeung, Rae S M;
Tan, Dennis E K;
Sim, Kar Seng;
Wang, Jie Jin;
Wong, Tien Yin;
Pang, Junxiong;
Mitchell, Paul;
Cimaz, Rolando;
Dahdah, Nagib;
Cheung, Yiu-Fai;
Huang, Guo-Ying;
Yang, Wanling;
Park, In-Sook;
Lee, Jong-Keuk

Publication type:

Article

Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1.

Published in:

Nature Genetics, 2011, v. 43, n. 11, p. 1139, doi. 10.1038/ng.960

By:

Khor, Chiea Chuen;
Chau, Tran Nguyen Bich;
Pang, Junxiong;
Davila, Sonia;
Long, Hoang Truong;
Ong, Rick T H;
Dunstan, Sarah J;
Wills, Bridget;
Farrar, Jeremy;
Van Tram, Ta;
Gan, Tran Thi;
Binh, Nguyen Thi Nguyet;
Tri, Le Trung;
Lien, Le Bich;
Tuan, Nguyen Minh;
Tham, Nguyen Thi Hong;
Lanh, Mai Ngoc;
Nguyet, Nguyen Minh;
Hieu, Nguyen Trong;
Van N Vinh Chau, Nguyen

Publication type:

Article

Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease.

Published in:

Nature Genetics, 2010, v. 42, n. 9, p. 772, doi. 10.1038/ng.640

By:

Davila, Sonia;
Wright, Victoria J.;
Chiea Chuen Khor;
Kar Seng Sim;
Binder, Alexander;
Breunis, Willemijn B.;
Inwald, David;
Nadel, Simon;
Betts, Helen;
Carrol, Enitan D.;
de Groot, Ronald;
Hermans, Peter W. M.;
Hazelzet, Jan;
Emonts, Marieke;
Chui Chin Lim;
Kuijpers, Taco W.;
Martinon-Torres, Federico;
Salas, Antonio;
Zenz, Werner;
Levin, Michael

Publication type:

Article

Effect of plasma polyunsaturated fatty acid levels on leukocyte telomere lengths in the Singaporean Chinese population.

Published in:

2020

By:

Chang, Xuling;
Dorajoo, Rajkumar;
Sun, Ye;
Wang, Ling;
Ong, Choon Nam;
Liu, Jianjun;
Khor, Chiea Chuen;
Yuan, Jian-Min;
Koh, Woon Puay;
Friedlander, Yechiel;
Heng, Chew-Kiat

Publication type:

journal article

Insights into the Genetic Structure and Diversity of 38 South Asian Indians from Deep Whole-Genome Sequencing.

Published in:

PLoS Genetics, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.pgen.1004377

By:

Wong, Lai-Ping;
Lai, Jason Kuan-Han;
Saw, Woei-Yuh;
Ong, Rick Twee-Hee;
Cheng, Anthony Youzhi;
Pillai, Nisha Esakimuthu;
Liu, Xuanyao;
Xu, Wenting;
Chen, Peng;
Foo, Jia-Nee;
Tan, Linda Wei-Lin;
Koo, Seok-Hwee;
Soong, Richie;
Wenk, Markus Rene;
Lim, Wei-Yen;
Khor, Chiea-Chuen;
Little, Peter;
Chia, Kee-Seng;
Teo, Yik-Ying

Publication type:

Article

<i>ABCC5</i>, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma.

Published in:

PLoS Genetics, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pgen.1004089

By:

Nongpiur, Monisha E.;
Khor, Chiea Chuen;
Jia, Hongyan;
Cornes, Belinda K.;
Chen, Li-Jia;
Qiao, Chunyan;
Nair, K. Saidas;
Cheng, Ching-Yu;
Xu, Liang;
George, Ronnie;
Tan, Do;
Abu-Amero, Khaled;
Perera, Shamira A.;
Ozaki, Mineo;
Mizoguchi, Takanori;
Kurimoto, Yasuo;
Low, Sancy;
Tajudin, Liza-Sharmini A.;
Ho, Ching-Lin;
Tham, Clement C. Y.

Publication type:

Article

Genetic Variants on Chromosome 1q41 Influence Ocular Axial Length and High Myopia.

Published in:

PLoS Genetics, 2012, v. 8, n. 6, p. 1, doi. 10.1371/journal.pgen.1002753

By:

Qiao Fan;
Barathi, Veluchamy A.;
Ching-Yu Cheng;
Xin Zhou;
Meguro, Akira;
Nakata, Isao;
Chiea-Chuen Khor;
Liang-Kee Goh;
Yi-Ju Li;
Wan'e Lim;
Ho, Candice E. H.;
Hawthorne, Felicia;
Yingfeng Zheng;
Chua, Daniel;
Inoko, Hidetoshi;
Yamashiro, Kenji;
Kyoko Ohno-Matsui;
Matsuo, Keitaro;
Matsuda, Fumihiko;
Vithana, Eranga

Publication type:

Article

Genome-Wide Meta-Analysis of Five Asian Cohorts Identifies PDGFRA as a Susceptibility Locus for Corneal Astigmatism.

Published in:

PLoS Genetics, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.pgen.1002402

By:

Qiao Fan;
Xin Zhou;
Chiea-Chuen Khor;
Ching-Yu Cheng;
Liang-Kee Goh;
Xueling Sim;
Wan-Ting Tay;
Yi-Ju Li;
Ong, Rick Twee-Hee;
Chen Suo;
Cornes, Belinda;
Ikram, Mohammad Kamran;
Kee-Seng Chia;
Seielstad, Mark;
Jianjun Liu;
Vithana, Eranga;
Young, Terri L.;
E.-Shyong Tai;
Tien-Yin Wong;
Aung, Tin

Publication type:

Article

Variation in predicted COVID‐19 risk among lemurs and lorises.

Published in:

American Journal of Primatology, 2021, v. 83, n. 6, p. 1, doi. 10.1002/ajp.23255

By:

Melin, Amanda D.;
Orkin, Joseph D.;
Janiak, Mareike C.;
Valenzuela, Alejandro;
Kuderna, Lukas;
Marrone, Frank;
Ramangason, Hasinala;
Horvath, Julie E.;
Roos, Christian;
Kitchener, Andrew C.;
Khor, Chiea Chuen;
Lim, Weng Khong;
Lee, Jessica G. H.;
Tan, Patrick;
Umapathy, Govindhaswamy;
Raveendran, Muthuswamy;
Alan Harris, R.;
Gut, Ivo;
Gut, Marta;
Lizano, Esther

Publication type:

Article

Whole-Genome Sequencing Analysis of Serially Isolated Multi-Drug and Extensively Drug Resistant Mycobacterium tuberculosis from Thai Patients.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0160992

By:

Faksri, Kiatichai;
Tan, Jun Hao;
Disratthakit, Areeya;
Xia, Eryu;
Prammananan, Therdsak;
Suriyaphol, Prapat;
Khor, Chiea Chuen;
Teo, Yik-Ying;
Ong, Rick Twee-Hee;
Chaiprasert, Angkana

Publication type:

Article

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

Published in:

Nature Genetics, 2015, v. 47, n. 11, p. 1282, doi. 10.1038/ng.3405

By:

Loh, Marie;
Zhang, Weihua;
Saleheen, Danish;
Wahl, Simone;
Tan, Sian-Tsung;
Scott, William R;
Afzal, Uzma;
Ahluwalia, Tarunveer S;
Esko, Tõnu;
Harris, Sarah E;
Hartiala, Jaana;
Khor, Chiea-Chuen;
Stewart, Alexandre F R;
Wu, Jer-Yuarn;
Zhang, Yi;
Lyytikäinen, Leo-Pekka;
Postmus, Iris;
Raitakari, Olli T;
Traglia, Michela;
Barroso, Inês

Publication type:

Article

Variation at HLA-DRB1 is associated with resistance to enteric fever.

Published in:

Nature Genetics, 2014, v. 46, n. 12, p. 1333, doi. 10.1038/ng.3143

By:

Dunstan, Sarah J;
Phuong, Le Thi;
Lanh, Mai Ngoc;
Do, Tan;
Hon, Do Nu;
Aung, Tin;
Teo, Yik Ying;
Hibberd, Martin L;
Okada, Yukinori;
Raychaudhuri, Soumya;
Simmons, Cameron P;
Baker, Stephen;
de Bakker, Paul I W;
Hue, Nguyen Thi;
Khor, Chiea Chuen;
Han, Buhm;
Li, Zheng;
Sim, Kar Seng;
Foo, Jia Nee;
Tram, Trinh Thi Bich

Publication type:

Article

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.

Published in:

Nature Genetics, 2014, v. 46, n. 10, p. 1126, doi. 10.1038/ng.3087

By:

Hysi, Pirro G;
Hammond, Christopher J;
Höhn, René;
Mirshahi, Alireza;
Pfeiffer, Norbert;
Venturini, Cristina;
Ramdas, Wishal D;
Vingerling, Johannes R;
Klaver, Caroline C W;
Thorleifsson, Gudmar;
Thorsteinsdottir, Unnur;
Stefansson, Kari;
Vithana, Eranga;
Khor, Chiea-Chuen;
Stefansson, Arni B;
Liao, Jiemin;
Haines, Jonathan L;
Amin, Najaf;
Karssen, Lennart C;
Iglesias, Adriana I

Publication type:

Article

Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma.

Published in:

Nature Genetics, 2014, v. 46, n. 10, p. 1115, doi. 10.1038/ng.3078

By:

Chen, Yuhong;
Luo, Qian;
Cheng, Yilian;
Yang, Quanyao;
Wang, Ningli;
Khor, Chiea Chuen;
Pang, Chi Pui;
Sun, Xinghuai;
Yang, Zhenglin;
Lin, Ying;
Vithana, Eranga N;
Jia, Liyun;
Zuo, Xianbo;
Zhang, Xuejun;
Wong, Tien Yin;
Li, Zheng;
Mani, Baskaran;
Guzman, Celeste;
Aung, Tin;
Chen, Li Jia

Publication type:

Article

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.

Published in:

Nature Genetics, 2013, v. 45, n. 2, p. 155, doi. 10.1038/ng.2506

By:

Lu, Yi;
Vitart, Veronique;
Burdon, Kathryn P;
Khor, Chiea Chuen;
Bykhovskaya, Yelena;
Mirshahi, Alireza;
Hewitt, Alex W;
Koehn, Demelza;
Hysi, Pirro G;
Ramdas, Wishal D;
Zeller, Tanja;
Vithana, Eranga N;
Cornes, Belinda K;
Tay, Wan-Ting;
Tai, E Shyong;
Cheng, Ching-Yu;
Liu, Jianjun;
Foo, Jia-Nee;
Saw, Seang Mei;
Thorleifsson, Gudmar

Publication type:

Article

Associations between OPA1, MFN1, and MFN2 polymorphisms and primary open angle glaucoma in Polish participants of European ancestry.

Published in:

2022

By:

Milanowski, Piotr;
Kosior-Jarecka, Ewa;
Łukasik, Urszula;
Wróbel-Dudzińska, Dominika;
Milanowska, Joanna;
Khor, Chiea Chuen;
Aung, Tin;
Kocki, Janusz;
Żarnowski, Tomasz

Publication type:

Report

Estrogen receptor gene polymorphisms and their influence on clinical status of Caucasian patients with primary open angle glaucoma.

Published in:

2019

By:

Kosior-Jarecka, Ewa;
Sagan, Małgorzata;
Wróbel-Dudzińska, Dominika;
Łukasik, Urszula;
Aung, Tin;
Khor, Chiea Chuen;
Kocki, Janusz;
Żarnowski, Tomasz

Publication type:

Report

HDL-cholesterol levels and risk of age-related macular degeneration: a multiethnic genetic study using Mendelian randomization.

Published in:

2017

By:

Qiao Fan;
Maranville, Joseph C.;
Fritsche, Lars;
Xueling Sim;
Chui Ming Gemmy Cheung;
Li Jia Chen;
Gorski, Mathias;
Yamashiro, Kenji;
Jeeyun Ahn;
Laude, Augustinus;
Dorajoo, Rajkumar;
Tock Han Lim;
Yik-Ying Teo;
Blaustein, Robert O.;
Yoshimura, Nagahisa;
Kyu-Hyung Park;
Chi Pui Pang;
Tai, E. Shyong;
Chiea Chuen Khor;
Tien Yin Wong

Publication type:

journal article

Systematic immune cell dysregulation and molecular subtypes revealed by single-cell RNA-seq of subjects with type 1 diabetes.

Published in:

Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01300-z

By:

Honardoost, Mohammad Amin;
Adinatha, Andreas;
Schmidt, Florian;
Ranjan, Bobby;
Ghaeidamini, Maryam;
Arul Rayan, Nirmala;
Gek Liang Lim, Michelle;
Joanito, Ignasius;
Xiao Xuan Lin, Quy;
Rajagopalan, Deepa;
Qi Mok, Shi;
Hwang, You Yi;
Larbi, Anis;
Khor, Chiea Chuen;
Foo, Roger;
Boehm, Bernhard Otto;
Prabhakar, Shyam

Publication type:

Article

Characterizing the genetic differences between two distinct migrant groups from Indo-European and Dravidian speaking populations in India.

Published in:

BMC Genetics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2156-15-86

By:

Ali, Mohammad;
Xuanyao Liu;
Pillai, Esakimuthu Nisha;
Peng Chen;
Chiea-Chuen Khor;
Rick Twee-Hee Ong;
Yik-Ying Teo

Publication type:

Article

A gene–brain–behavior basis for familiarity bias in source preference.

Published in:

Theory & Decision, 2022, v. 92, n. 3/4, p. 531, doi. 10.1007/s11238-022-09871-2

By:

Chark, Robin;
Zhong, Songfa;
Tsang, Shui Ying;
Khor, Chiea Chuen;
Ebstein, Richard P.;
Xue, Hong;
Chew, Soo Hong

Publication type:

Article

iCall: a genotype-calling algorithm for rare, low-frequency and common variants on the Illumina exome array.

Published in:

Bioinformatics, 2014, v. 30, n. 12, p. 1714, doi. 10.1093/bioinformatics/btu107

By:

Zhou, Jin;
Tantoso, Erwin;
Wong, Lai-Ping;
Ong, Rick Twee-Hee;
Bei, Jin-Xin;
Li, Yi;
Liu, Jianjun;
Khor, Chiea-Chuen;
Teo, Yik-Ying

Publication type:

Article

An Evaluation of DNA Methyltransferase 1 (DNMT1) Single Nucleotide Polymorphisms and Chemotherapy-Associated Cognitive Impairment: A Prospective, Longitudinal Study.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-51203-y

By:

Chan, Alexandre;
Yeo, Angie;
Shwe, Maung;
Tan, Chia Jie;
Foo, Koon Mian;
Chu, Pat;
Khor, Chiea Chuen;
Ho, Han Kiat

Publication type:

Article

Novel mutation G324C in WNT1 mapped in a large Pakistani family with severe recessively inherited Osteogenesis Imperfecta.

Published in:

Journal of Biomedical Science, 2018, v. 25, n. 1, p. N.PAG, doi. 10.1186/s12929-018-0481-x

By:

Kausar, Mehran;
Siddiqi, Saima;
Yaqoob, Muhammad;
Mansoor, Sajid;
Makitie, Outi;
Mir, Asif;
Khor, Chiea Chuen;
Foo, Jia Nee;
Anees, Mariam

Publication type:

Article

Combined genotype and haplotype tests for region-based association studies.

Published in:

BMC Genomics, 2013, v. 14, n. 1, p. 569, doi. 10.1186/1471-2164-14-569

By:

Zakharov, Sergii;
Wong, Tien Yin;
Aung, Tin;
Vithana, Eranga Nishanthie;
Khor, Chiea Chuen;
Salim, Agus;
Thalamuthu, Anbupalam

Publication type:

Article

Identification of a recurrent nonsense mutation in HR gene responsible for atrichia with papular lesions in two Kashmiri families.

Published in:

Journal of Gene Medicine, 2020, v. 22, n. 5, p. 1, doi. 10.1002/jgm.3167

By:

Ali, Ghazanfar;
Awan, Naheed Bashir;
Sadia;
Khawaja, Abdul Waheed;
Foo, Jia Nee;
Khor, Chiea Chuen;
Chang, Chu‐Hua;
Chew, Elaine GuoYan;
Kiani, Farhat Rafique;
Jelani, Musharraf

Publication type:

Article

A recurrent missense mutation in the EDAR gene causes severe autosomal recessive hypohidrotic ectodermal dysplasia in two consanguineous Kashmiri families.

Published in:

Journal of Gene Medicine, 2019, v. 21, n. 9, p. N.PAG, doi. 10.1002/jgm.3113

By:

Sadia;
Foo, Jia Nee;
Khor, Chiea Chuen;
Jelani, Musharraf;
Ali, Ghazanfar

Publication type:

Article