Works by Khomutov, Alex R.

Results: 22

Enzymatic Synthesis of Biologically Active H -Phosphinic Analogue of α-Ketoglutarate.
Published in:
Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1574, doi. 10.3390/biom14121574
By:
- Filonov, Vsevolod L.;
- Khomutov, Maxim A.;
- Tkachev, Yaroslav V.;
- Udod, Artem V.;
- Yanvarev, Dmitry V.;
- Giovannercole, Fabio;
- Khurs, Elena N.;
- Kochetkov, Sergei N.;
- De Biase, Daniela;
- Khomutov, Alex R.
Publication type:
Article
A Desmethylphosphinothricin Dipeptide Derivative Effectively Inhibits Escherichia coli and Bacillus subtilis Growth.
Published in:
Biomolecules (2218-273X), 2023, v. 13, n. 10, p. 1451, doi. 10.3390/biom13101451
By:
- Khomutov, Maxim A.;
- Giovannercole, Fabio;
- Onillon, Laura;
- Demiankova, Marija V.;
- Vasilieva, Byazilya F.;
- Salikhov, Arthur I.;
- Kochetkov, Sergey N.;
- Efremenkova, Olga V.;
- Khomutov, Alex R.;
- De Biase, Daniela
Publication type:
Article
C -Methylated Spermidine Derivatives: Convenient Syntheses and Antizyme-Related Effects.
Published in:
Biomolecules (2218-273X), 2023, v. 13, n. 6, p. 916, doi. 10.3390/biom13060916
By:
- Khomutov, Maxim A.;
- Salikhov, Arthur I.;
- Mitkevich, Vladimir A.;
- Tunitskaya, Vera L.;
- Smirnova, Olga A.;
- Korolev, Sergey P.;
- Chizhov, Alexander O.;
- Gottikh, Marina B.;
- Kochetkov, Sergey N.;
- Khomutov, Alex R.
Publication type:
Article
Biogenic Polyamines and Related Metabolites.
Published in:
Biomolecules (2218-273X), 2022, v. 12, n. 1, p. 14, doi. 10.3390/biom12010014
By:
- Ivanov, Alexander V.;
- Khomutov, Alex R.
Publication type:
Article
α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation.
Published in:
Biomolecules (2218-273X), 2021, v. 11, n. 5, p. 707, doi. 10.3390/biom11050707
By:
- Hyvönen, Mervi T.;
- Khomutov, Maxim;
- Vepsäläinen, Jouko;
- Khomutov, Alex R.;
- Keinänen, Tuomo A.;
- Uversky, Vladimir N.
Publication type:
Article
Hydroxylamine Analogue of Agmatine: Magic Bullet for Arginine Decarboxylase.
Published in:
Biomolecules (2218-273X), 2020, v. 10, n. 3, p. 406, doi. 10.3390/biom10030406
By:
- Hyvönen, Mervi T.;
- Keinänen, Tuomo A.;
- Nuraeva, Gulgina K.;
- Yanvarev, Dmitry V.;
- Khomutov, Maxim;
- Khurs, Elena N.;
- Kochetkov, Sergey N.;
- Vepsäläinen, Jouko;
- Zhgun, Alexander A.;
- Khomutov, Alex R.
Publication type:
Article
In search for structural targets for engineering D-amino acid transaminase: modulation of pH optimum and substrate specificity.
Published in:
Biochemical Journal, 2023, v. 480, n. 16, p. 1267, doi. 10.1042/BCJ20230233
By:
- Shilova, Sofia A.;
- Matyuta, Ilya O.;
- Khrenova, Maria G.;
- Nikolaeva, Alena Y.;
- Klyachko, Natalia L.;
- Minyaev, Mikhail E.;
- Khomutov, Alex R.;
- Boyko, Konstantin M.;
- Popov, Vladimir O.;
- Bezsudnova, Ekaterina Yu.
Publication type:
Article
Hepatitis C Virus Dysregulates Polyamine and Proline Metabolism and Perturbs the Urea Cycle.
Published in:
Cells (2073-4409), 2024, v. 13, n. 12, p. 1036, doi. 10.3390/cells13121036
By:
- Zakirova, Natalia F.;
- Khomich, Olga A.;
- Smirnova, Olga A.;
- Molle, Jennifer;
- Duponchel, Sarah;
- Yanvarev, Dmitry V.;
- Valuev-Elliston, Vladimir T.;
- Monnier, Lea;
- Grigorov, Boyan;
- Ivanova, Olga N.;
- Karpenko, Inna L.;
- Golikov, Mikhail V.;
- Bovet, Cedric;
- Rindlisbacher, Barbara;
- Khomutov, Alex R.;
- Kochetkov, Sergey N.;
- Bartosch, Birke;
- Ivanov, Alexander V.
Publication type:
Article
Inhibition of nicotinic acetylcholine receptors by oligoarginine peptides and polyamine-related compounds.
Published in:
Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1327603
By:
- Ojomoko, Lucy O.;
- Kryukova, Elena V.;
- Egorova, Natalya S.;
- Salikhov, Arthur I.;
- Epifanova, Lyubov A.;
- Denisova, Daria A.;
- Khomutov, Alex R.;
- Sukhov, Dmitry A.;
- Vassilevski, Alexander A.;
- Khomutov, Maxim A.;
- Tsetlin, Victor I.;
- Shelukhina, Irina V.
Publication type:
Article
Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.
Published in:
Journal of Cellular & Molecular Medicine, 2010, v. 14, n. 6b, p. 1683, doi. 10.1111/j.1582-4934.2009.00808.x
By:
- Vuohelainen, Susanna;
- Pirinen, Eija;
- Cerrada-Gimenez, Marc;
- Keinänen, Tuomo A.;
- Uimari, Anne;
- Pietil, Marko;
- Khomutov, Alex R.;
- Jänne, Juhani;
- Alhonen, Leena
Publication type:
Article
Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives.
Published in:
ARKIVOC: Online Journal of Organic Chemistry, 2015, v. 2015, p. 42, doi. 10.3998/ark.5550190.p009.169
By:
- Ucal, Sebahat;
- Khomutov, Alex R.;
- Häkkinen, Merja R.;
- Turhanen, Petri A.;
- Vepsäläinen, Jouko J.;
- Weisell, Janne
Publication type:
Article
Triethylenetetramine modulates polyamine and energy metabolism and inhibits cancer cell proliferation.
Published in:
Biochemical Journal, 2016, v. 473, n. 10, p. 1433, doi. 10.1042/BCJ20160134
By:
- Hyvönen, Mervi T.;
- Ucal, Sebahat;
- Pasanen, Markku;
- Peräniemi, Sirpa;
- Weisell, Janne;
- Khomutov, Maxim;
- Khomutov, Alex R.;
- Vepsäläinen, Jouko;
- Alhonen, Leena;
- Keinänen, Tuomo A.
Publication type:
Article
Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A.
Published in:
Biochemical Journal, 2013, v. 453, n. 3, p. 467, doi. 10.1042/BJ20130263
By:
- HYVÖNEN, Mervi T.;
- KOPONEN, Taina;
- WEISELL, Janne;
- PIETILÄ, Marko;
- KHOMUTOV, Alex R.;
- VEPSÄLÄINEN, Jouko;
- ALHONEN, Leena;
- KEINÄNEN, Tuomo A.
Publication type:
Article
Organophosphorus S-adenosyl-L-methionine mimetics: synthesis, stability, and substrate properties.
Published in:
Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1448747
By:
- Rudenko, Alexander Yu;
- Mariasina, Sofia S.;
- Bolikhova, Anastasiia K.;
- Nikulin, Maxim V.;
- Ozhiganov, Ratislav M.;
- Vasil'ev, Vasiliy G.;
- Ikhalaynen, Yuri A.;
- Khandazhinskaya, Anastasia L.;
- Khomutov, Maxim A.;
- Sergiev, Peter V.;
- Khomutov, Alex R.;
- Polshakov, Vladimir I.;
- Comstock, Lindsay;
- Sohtome, Yoshihiro
Publication type:
Article
Role of Polyamine-Induced Dimerization of Antizyme in Its Cellular Functions.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4614, doi. 10.3390/ijms23094614
By:
- Hyvönen, Mervi T.;
- Smirnova, Olga A.;
- Mitkevich, Vladimir A.;
- Tunitskaya, Vera L.;
- Khomutov, Maxim;
- Karpov, Dmitry S.;
- Korolev, Sergey P.;
- Häkkinen, Merja R.;
- Pietilä, Marko;
- Gottikh, Marina B.;
- Vepsäläinen, Jouko;
- Alhonen, Leena;
- Makarov, Alexander A.;
- Kochetkov, Sergey N.;
- Wallace, Heather M.;
- Keinänen, Tuomo A.;
- Khomutov, Alex R.
Publication type:
Article
Antibacterial Activity of Peptide Derivatives of Phosphinothricin against Multidrug-Resistant Klebsiella pneumoniae.
Published in:
Molecules, 2023, v. 28, n. 3, p. 1234, doi. 10.3390/molecules28031234
By:
- Demiankova, Marija V.;
- Giovannercole, Fabio;
- Khomutov, Maxim A.;
- Salikhov, Arthur I.;
- Onillon, Laura;
- Valuev-Elliston, Vladimir T.;
- Vasilieva, Byazilya F.;
- Khurs, Elena N.;
- Gabrielyan, Nina I.;
- Kochetkov, Sergey N.;
- Efremenkova, Olga V.;
- De Biase, Daniela;
- Khomutov, Alex R.
Publication type:
Article
On the Reaction of Carbonyl Diphosphonic Acid with Hydroxylamine and O-alkylhydroxylamines: Unexpected Degradation of P-C-P Bridge.
Published in:
Molecules, 2017, v. 22, n. 7, p. 1040, doi. 10.3390/molecules22071040
By:
- Khomich, Olga A.;
- Yanvarev, Dmitry V.;
- Novikov, Roman A.;
- Kornev, Alexey B.;
- Puljulla, Elina;
- Vepsäläinen, Jouko;
- Khomutov, Alex R.;
- Kochetkov, Sergey N.
Publication type:
Article
Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome.
Published in:
EMBO Molecular Medicine, 2023, v. 15, n. 11, p. 1, doi. 10.15252/emmm.202317833
By:
- Stewart, Tracy Murray;
- Foley, Jackson R;
- Holbert, Cassandra E;
- Khomutov, Maxim;
- Rastkari, Noushin;
- Tao, Xianzun;
- Khomutov, Alex R;
- Zhai, R Grace;
- Casero, Robert A
Publication type:
Article
Metabolism of N-alkylated spermine analogues by polyamine and spermine oxidases.
Published in:
Amino Acids, 2010, v. 38, n. 2, p. 369, doi. 10.1007/s00726-009-0429-2
By:
- Häkkinen, Merja R.;
- Hyvönen, Mervi T.;
- Auriola, Seppo;
- Casero Jr., Robert A.;
- Vepsäläinen, Jouko;
- Khomutov, Alex R.;
- Alhonen, Leena;
- Keinänen, Tuomo A.
Publication type:
Article
α-Methylspermidine protects against carbon tetrachloride-induced hepatic and pancreatic damage.
Published in:
Amino Acids, 2010, v. 38, n. 2, p. 575, doi. 10.1007/s00726-009-0418-5
By:
- Hyvönen, Mervi T.;
- Sinervirta, Riitta;
- Grigorenko, Nikolay;
- Khomutov, Alex R.;
- Vepsäläinen, Jouko;
- Keinänen, Tuomo A.;
- Alhonen, Leena
Publication type:
Article
Novel isosteric charge-deficient spermine analogue—1,12-diamino-3,6,9-triazadodecane: synthesis, p K<sub>a</sub> measurement and biological activity.
Published in:
Amino Acids, 2010, v. 38, n. 2, p. 501, doi. 10.1007/s00726-009-0409-6
By:
- Weisell, Janne;
- Hyvönen, Mervi T.;
- Vepsäläinen, Jouko;
- Alhonen, Leena;
- Keinänen, Tuomo A.;
- Khomutov, Alex R.;
- Soininen, Pasi
Publication type:
Article
Cutaneous application of α-methylspermidine activates the growth of resting hair follicles in mice.
Published in:
Amino Acids, 2010, v. 38, n. 2, p. 583, doi. 10.1007/s00726-009-0421-x
By:
- Fashe, Tekele M.;
- Keinänen, Tuomo A.;
- Grigorenko, Nikolay A.;
- Khomutov, Alex R.;
- Jänne, Juhani;
- Alhonen, Leena;
- Pietila, Marko
Publication type:
Article