Works by Khomutov, Alex R.

Results: 22

Hepatitis C Virus Dysregulates Polyamine and Proline Metabolism and Perturbs the Urea Cycle.

Published in:

Cells (2073-4409), 2024, v. 13, n. 12, p. 1036, doi. 10.3390/cells13121036

By:

Zakirova, Natalia F.;
Khomich, Olga A.;
Smirnova, Olga A.;
Molle, Jennifer;
Duponchel, Sarah;
Yanvarev, Dmitry V.;
Valuev-Elliston, Vladimir T.;
Monnier, Lea;
Grigorov, Boyan;
Ivanova, Olga N.;
Karpenko, Inna L.;
Golikov, Mikhail V.;
Bovet, Cedric;
Rindlisbacher, Barbara;
Khomutov, Alex R.;
Kochetkov, Sergey N.;
Bartosch, Birke;
Ivanov, Alexander V.

Publication type:

Article

Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.

Published in:

Journal of Cellular & Molecular Medicine, 2010, v. 14, n. 6b, p. 1683, doi. 10.1111/j.1582-4934.2009.00808.x

By:

Vuohelainen, Susanna;
Pirinen, Eija;
Cerrada-Gimenez, Marc;
Keinänen, Tuomo A.;
Uimari, Anne;
Pietil, Marko;
Khomutov, Alex R.;
Jänne, Juhani;
Alhonen, Leena

Publication type:

Article

Role of Polyamine-Induced Dimerization of Antizyme in Its Cellular Functions.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4614, doi. 10.3390/ijms23094614

By:

Hyvönen, Mervi T.;
Smirnova, Olga A.;
Mitkevich, Vladimir A.;
Tunitskaya, Vera L.;
Khomutov, Maxim;
Karpov, Dmitry S.;
Korolev, Sergey P.;
Häkkinen, Merja R.;
Pietilä, Marko;
Gottikh, Marina B.;
Vepsäläinen, Jouko;
Alhonen, Leena;
Makarov, Alexander A.;
Kochetkov, Sergey N.;
Wallace, Heather M.;
Keinänen, Tuomo A.;
Khomutov, Alex R.

Publication type:

Article

Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2015, v. 2015, p. 42, doi. 10.3998/ark.5550190.p009.169

By:

Ucal, Sebahat;
Khomutov, Alex R.;
Häkkinen, Merja R.;
Turhanen, Petri A.;
Vepsäläinen, Jouko J.;
Weisell, Janne

Publication type:

Article

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome.

Published in:

EMBO Molecular Medicine, 2023, v. 15, n. 11, p. 1, doi. 10.15252/emmm.202317833

By:

Stewart, Tracy Murray;
Foley, Jackson R;
Holbert, Cassandra E;
Khomutov, Maxim;
Rastkari, Noushin;
Tao, Xianzun;
Khomutov, Alex R;
Zhai, R Grace;
Casero, Robert A

Publication type:

Article

Metabolism of N-alkylated spermine analogues by polyamine and spermine oxidases.

Published in:

Amino Acids, 2010, v. 38, n. 2, p. 369, doi. 10.1007/s00726-009-0429-2

By:

Häkkinen, Merja R.;
Hyvönen, Mervi T.;
Auriola, Seppo;
Casero Jr., Robert A.;
Vepsäläinen, Jouko;
Khomutov, Alex R.;
Alhonen, Leena;
Keinänen, Tuomo A.

Publication type:

Article

α-Methylspermidine protects against carbon tetrachloride-induced hepatic and pancreatic damage.

Published in:

Amino Acids, 2010, v. 38, n. 2, p. 575, doi. 10.1007/s00726-009-0418-5

By:

Hyvönen, Mervi T.;
Sinervirta, Riitta;
Grigorenko, Nikolay;
Khomutov, Alex R.;
Vepsäläinen, Jouko;
Keinänen, Tuomo A.;
Alhonen, Leena

Publication type:

Article

Novel isosteric charge-deficient spermine analogue—1,12-diamino-3,6,9-triazadodecane: synthesis, p K<sub>a</sub> measurement and biological activity.

Published in:

Amino Acids, 2010, v. 38, n. 2, p. 501, doi. 10.1007/s00726-009-0409-6

By:

Weisell, Janne;
Hyvönen, Mervi T.;
Vepsäläinen, Jouko;
Alhonen, Leena;
Keinänen, Tuomo A.;
Khomutov, Alex R.;
Soininen, Pasi

Publication type:

Article

Cutaneous application of α-methylspermidine activates the growth of resting hair follicles in mice.

Published in:

Amino Acids, 2010, v. 38, n. 2, p. 583, doi. 10.1007/s00726-009-0421-x

By:

Fashe, Tekele M.;
Keinänen, Tuomo A.;
Grigorenko, Nikolay A.;
Khomutov, Alex R.;
Jänne, Juhani;
Alhonen, Leena;
Pietila, Marko

Publication type:

Article

Enzymatic Synthesis of Biologically Active H -Phosphinic Analogue of α-Ketoglutarate.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1574, doi. 10.3390/biom14121574

By:

Filonov, Vsevolod L.;
Khomutov, Maxim A.;
Tkachev, Yaroslav V.;
Udod, Artem V.;
Yanvarev, Dmitry V.;
Giovannercole, Fabio;
Khurs, Elena N.;
Kochetkov, Sergei N.;
De Biase, Daniela;
Khomutov, Alex R.

Publication type:

Article

A Desmethylphosphinothricin Dipeptide Derivative Effectively Inhibits Escherichia coli and Bacillus subtilis Growth.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 10, p. 1451, doi. 10.3390/biom13101451

By:

Khomutov, Maxim A.;
Giovannercole, Fabio;
Onillon, Laura;
Demiankova, Marija V.;
Vasilieva, Byazilya F.;
Salikhov, Arthur I.;
Kochetkov, Sergey N.;
Efremenkova, Olga V.;
Khomutov, Alex R.;
De Biase, Daniela

Publication type:

Article

C -Methylated Spermidine Derivatives: Convenient Syntheses and Antizyme-Related Effects.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 6, p. 916, doi. 10.3390/biom13060916

By:

Khomutov, Maxim A.;
Salikhov, Arthur I.;
Mitkevich, Vladimir A.;
Tunitskaya, Vera L.;
Smirnova, Olga A.;
Korolev, Sergey P.;
Chizhov, Alexander O.;
Gottikh, Marina B.;
Kochetkov, Sergey N.;
Khomutov, Alex R.

Publication type:

Article

Biogenic Polyamines and Related Metabolites.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 1, p. 14, doi. 10.3390/biom12010014

By:

Ivanov, Alexander V.;
Khomutov, Alex R.

Publication type:

Article

α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 5, p. 707, doi. 10.3390/biom11050707

By:

Hyvönen, Mervi T.;
Khomutov, Maxim;
Vepsäläinen, Jouko;
Khomutov, Alex R.;
Keinänen, Tuomo A.;
Uversky, Vladimir N.

Publication type:

Article

Hydroxylamine Analogue of Agmatine: Magic Bullet for Arginine Decarboxylase.

Published in:

Biomolecules (2218-273X), 2020, v. 10, n. 3, p. 406, doi. 10.3390/biom10030406

By:

Hyvönen, Mervi T.;
Keinänen, Tuomo A.;
Nuraeva, Gulgina K.;
Yanvarev, Dmitry V.;
Khomutov, Maxim;
Khurs, Elena N.;
Kochetkov, Sergey N.;
Vepsäläinen, Jouko;
Zhgun, Alexander A.;
Khomutov, Alex R.

Publication type:

Article

In search for structural targets for engineering D-amino acid transaminase: modulation of pH optimum and substrate specificity.

Published in:

Biochemical Journal, 2023, v. 480, n. 16, p. 1267, doi. 10.1042/BCJ20230233

By:

Shilova, Sofia A.;
Matyuta, Ilya O.;
Khrenova, Maria G.;
Nikolaeva, Alena Y.;
Klyachko, Natalia L.;
Minyaev, Mikhail E.;
Khomutov, Alex R.;
Boyko, Konstantin M.;
Popov, Vladimir O.;
Bezsudnova, Ekaterina Yu.

Publication type:

Article

Triethylenetetramine modulates polyamine and energy metabolism and inhibits cancer cell proliferation.

Published in:

Biochemical Journal, 2016, v. 473, n. 10, p. 1433, doi. 10.1042/BCJ20160134

By:

Hyvönen, Mervi T.;
Ucal, Sebahat;
Pasanen, Markku;
Peräniemi, Sirpa;
Weisell, Janne;
Khomutov, Maxim;
Khomutov, Alex R.;
Vepsäläinen, Jouko;
Alhonen, Leena;
Keinänen, Tuomo A.

Publication type:

Article

Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A.

Published in:

Biochemical Journal, 2013, v. 453, n. 3, p. 467, doi. 10.1042/BJ20130263

By:

HYVÖNEN, Mervi T.;
KOPONEN, Taina;
WEISELL, Janne;
PIETILÄ, Marko;
KHOMUTOV, Alex R.;
VEPSÄLÄINEN, Jouko;
ALHONEN, Leena;
KEINÄNEN, Tuomo A.

Publication type:

Article

Inhibition of nicotinic acetylcholine receptors by oligoarginine peptides and polyamine-related compounds.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1327603

By:

Ojomoko, Lucy O.;
Kryukova, Elena V.;
Egorova, Natalya S.;
Salikhov, Arthur I.;
Epifanova, Lyubov A.;
Denisova, Daria A.;
Khomutov, Alex R.;
Sukhov, Dmitry A.;
Vassilevski, Alexander A.;
Khomutov, Maxim A.;
Tsetlin, Victor I.;
Shelukhina, Irina V.

Publication type:

Article

Organophosphorus S-adenosyl-L-methionine mimetics: synthesis, stability, and substrate properties.

Published in:

Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1448747

By:

Rudenko, Alexander Yu;
Mariasina, Sofia S.;
Bolikhova, Anastasiia K.;
Nikulin, Maxim V.;
Ozhiganov, Ratislav M.;
Vasil'ev, Vasiliy G.;
Ikhalaynen, Yuri A.;
Khandazhinskaya, Anastasia L.;
Khomutov, Maxim A.;
Sergiev, Peter V.;
Khomutov, Alex R.;
Polshakov, Vladimir I.;
Comstock, Lindsay;
Sohtome, Yoshihiro

Publication type:

Article

Antibacterial Activity of Peptide Derivatives of Phosphinothricin against Multidrug-Resistant Klebsiella pneumoniae.

Published in:

Molecules, 2023, v. 28, n. 3, p. 1234, doi. 10.3390/molecules28031234

By:

Demiankova, Marija V.;
Giovannercole, Fabio;
Khomutov, Maxim A.;
Salikhov, Arthur I.;
Onillon, Laura;
Valuev-Elliston, Vladimir T.;
Vasilieva, Byazilya F.;
Khurs, Elena N.;
Gabrielyan, Nina I.;
Kochetkov, Sergey N.;
Efremenkova, Olga V.;
De Biase, Daniela;
Khomutov, Alex R.

Publication type:

Article

On the Reaction of Carbonyl Diphosphonic Acid with Hydroxylamine and O-alkylhydroxylamines: Unexpected Degradation of P-C-P Bridge.

Published in:

Molecules, 2017, v. 22, n. 7, p. 1040, doi. 10.3390/molecules22071040

By:

Khomich, Olga A.;
Yanvarev, Dmitry V.;
Novikov, Roman A.;
Kornev, Alexey B.;
Puljulla, Elina;
Vepsäläinen, Jouko;
Khomutov, Alex R.;
Kochetkov, Sergey N.

Publication type:

Article