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Amyloid precursor protein selective gammasecretase inhibitors for treatment of Alzheimer's disease.
- Published in:
- Alzheimer's Research & Therapy, 2010, v. 2, n. 6, p. 1, doi. 10.1186/alzrt60
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- Article
Antibody Capture of Soluble Aβ Does Not Reduce Cortical Aβ Amyloidosis in the PDAPP Mouse.
- Published in:
- Neurodegenerative Diseases, 2008, v. 5, n. 2, p. 65, doi. 10.1159/000112834
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- Publication type:
- Article
Pharmacokinetic and pharmacodynamic investigation of ELND006, a novel APP-selective gamma-secretase inhibitor, on amyloid-β concentrations in the brain, CSF and plasma of multiple nonclinical species following oral administration
- Published in:
- 2010
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- Publication type:
- Abstract
Effects of single and multiple dose oral administration of ELND006, a novel APP-selective gamma-secretase inhibitor, on amyloid-β concentrations in the brain and CSF of cynomolgus monkeys
- Published in:
- 2010
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- Publication type:
- Abstract
APP-selective gamma secretase inhibitor ELND006 effects on brain parenchymal and vascular amyloid beta in the PDAPP mouse model of Alzheimer's disease
- Published in:
- 2010
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- Publication type:
- Abstract
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse.
- Published in:
- Nature, 1999, v. 400, n. 6740, p. 173, doi. 10.1038/22124
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- Publication type:
- Article
Peripherally administered antibodies against amyloid B-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease.
- Published in:
- Nature Medicine, 2000, v. 6, n. 8, p. 916, doi. 10.1038/78682
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- Publication type:
- Article