Works by Khetarpal, Vinod

Results: 12
    1

    In Vivo Cerebral Imaging of Mutant Huntingtin Aggregates Using <sup>11</sup>C-CHDI-180R PET in a Nonhuman Primate Model of Huntington Disease.

    Published in:
    Journal of Nuclear Medicine, 2023, v. 64, n. 10, p. 1581, doi. 10.2967/jnumed.123.265569
    By:
    • Bertoglio, Daniele;
    • Weiss, Alison R.;
    • Liguore, William;
    • Martin, Lauren Drew;
    • Hobbs, Theodore;
    • Templon, John;
    • Srinivasan, Sathya;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Khetarpal, Vinod;
    • Verhaeghe, Jeroen;
    • Staelens, Steven;
    • Link, Jeanne;
    • Liu, Longbin;
    • Bard, Jonathan A.;
    • McBride, Jodi L.
    Publication type:
    Article
    2

    Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System.

    Published in:
    Cells (2073-4409), 2020, v. 9, n. 4, p. 994, doi. 10.3390/cells9040994
    By:
    • Di Marco, Annalise;
    • Vignone, Domenico;
    • Gonzalez Paz, Odalys;
    • Fini, Ivan;
    • Battista, Maria Rosaria;
    • Cellucci, Antonella;
    • Bracacel, Elena;
    • Auciello, Giulio;
    • Veneziano, Maria;
    • Khetarpal, Vinod;
    • Rose, Mark;
    • Rosa, Alessandro;
    • Gloaguen, Isabelle;
    • Monteagudo, Edith;
    • Herbst, Todd;
    • Dominguez, Celia;
    • Muñoz-Sanjuán, Ignacio
    Publication type:
    Article
    3
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    5

    Modelling the Human Blood–Brain Barrier in Huntington Disease.

    Published in:
    International Journal of Molecular Sciences, 2022, v. 23, n. 14, p. 7813, doi. 10.3390/ijms23147813
    By:
    • Vignone, Domenico;
    • Gonzalez Paz, Odalys;
    • Fini, Ivan;
    • Cellucci, Antonella;
    • Auciello, Giulio;
    • Battista, Maria Rosaria;
    • Gloaguen, Isabelle;
    • Fortuni, Silvia;
    • Cariulo, Cristina;
    • Khetarpal, Vinod;
    • Dominguez, Celia;
    • Muñoz-Sanjuán, Ignacio;
    • Di Marco, Annalise
    Publication type:
    Article
    6

    Preclinical evaluation of the novel [<sup>18</sup>F]CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2024, v. 52, n. 1, p. 122, doi. 10.1007/s00259-024-06880-x
    By:
    • Zajicek, Franziska;
    • Verhaeghe, Jeroen;
    • De Lombaerde, Stef;
    • Van Eetveldt, Annemie;
    • Miranda, Alan;
    • Munoz-Sanjuan, Ignacio;
    • Dominguez, Celia;
    • Khetarpal, Vinod;
    • Bard, Jonathan;
    • Liu, Longbin;
    • Staelens, Steven;
    • Bertoglio, Daniele
    Publication type:
    Article
    7

    Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [<sup>11</sup>C]CHDI-00485180-R and [<sup>11</sup>C]CHDI-00485626, designed for quantification of cerebral aggregated mutant huntingtin.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 50, n. 1, p. 48, doi. 10.1007/s00259-022-05945-z
    By:
    • Delva, Aline;
    • Koole, Michel;
    • Serdons, Kim;
    • Bormans, Guy;
    • Liu, Longbin;
    • Bard, Jonathan;
    • Khetarpal, Vinod;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Wood, Andrew;
    • Skinbjerg, Mette;
    • Wang, Yuchuan;
    • Vandenberghe, Wim;
    • Van Laere, Koen
    Publication type:
    Article
    8

    Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington's disease.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 4, p. 1166, doi. 10.1007/s00259-021-05578-8
    By:
    • Bertoglio, Daniele;
    • Verhaeghe, Jeroen;
    • Miranda, Alan;
    • Wyffels, Leonie;
    • Stroobants, Sigrid;
    • Mrzljak, Ladislav;
    • Khetarpal, Vinod;
    • Skinbjerg, Mette;
    • Liu, Longbin;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Bard, Jonathan;
    • Staelens, Steven
    Publication type:
    Article
    9
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    11

    Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.

    Published in:
    Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97334-z
    By:
    • Herrmann, Frank;
    • Hessmann, Manuela;
    • Schaertl, Sabine;
    • Berg-Rosseburg, Karola;
    • Brown, Christopher J;
    • Bursow, Galina;
    • Chiki, Anass;
    • Ebneth, Andreas;
    • Gehrmann, Miriam;
    • Hoeschen, Nicole;
    • Hotze, Madlen;
    • Jahn, Stefanie;
    • Johnson, Peter D;
    • Khetarpal, Vinod;
    • Kiselyov, Alex;
    • Kottig, Karsten;
    • Ladewig, Stefanie;
    • Lashuel, Hilal;
    • Letschert, Sven;
    • Mills, Matthew R
    Publication type:
    Article
    12

    Development of a ligand for in vivo imaging of mutant huntingtin in Huntington's disease.

    Published in:
    Science Translational Medicine, 2022, v. 14, n. 630, p. 1, doi. 10.1126/scitranslmed.abm3682
    By:
    • Bertoglio, Daniele;
    • Bard, Jonathan;
    • Hessmann, Manuela;
    • Liu, Longbin;
    • Gärtner, Annette;
    • De Lombaerde, Stef;
    • Huscher, Britta;
    • Zajicek, Franziska;
    • Miranda, Alan;
    • Peters, Finn;
    • Herrmann, Frank;
    • Schaertl, Sabine;
    • Vasilkovska, Tamara;
    • Brown, Christopher J.;
    • Johnson, Peter D.;
    • Prime, Michael E.;
    • Mills, Matthew R.;
    • Van der Linden, Annemie;
    • Mrzljak, Ladislav;
    • Khetarpal, Vinod
    Publication type:
    Article