Works by Kharkar, Prashant

Results: 34

Study of degradation behavior of besifloxacin, characterization of its degradation products by LC–ESI–QTOF–MS and their in silico toxicity prediction.

Published in:

Biomedical Chromatography, 2019, v. 33, n. 6, p. N.PAG, doi. 10.1002/bmc.4489

By:

Salunke, Nishant;
Kharkar, Prashant S.;
Pandita, Nancy

Publication type:

Article

Mycophenolic acid isobutanolammonium salt: synthesis, structural characterization, and solubility investigations.

Published in:

Journal of Thermal Analysis & Calorimetry, 2023, v. 148, n. 10, p. 4247, doi. 10.1007/s10973-023-12046-y

By:

Bagwe, Pritam V.;
Thakur, Vaibhavi P.;
Kharkar, Prashant S.;
Joshi, Shreerang V.

Publication type:

Article

Targeted therapies for Glioblastoma multiforme (GBM): State‐of‐the‐art and future prospects.

Published in:

Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.22261

By:

Satish, Smera;
Athavale, Maithili;
Kharkar, Prashant S.

Publication type:

Article

Covalent inhibitors: An ambitious approach for the discovery of newer oncotherapeutics.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22132

By:

Cheke, Rameshwar S.;
Kharkar, Prashant S.

Publication type:

Article

Hit discovery of novel 2‐phenyl‐substituted 4‐amino–6,7‐dihydro‐5H‐cyclopenta[d]pyrimidines as potential anti‐glioblastoma therapeutics: Design, synthesis, biological evaluation, and computational screening.

Published in:

Drug Development Research, 2023, v. 84, n. 3, p. 561, doi. 10.1002/ddr.22046

By:

Khairnar, Sanjay;
Sonawane, Anjali;
Cheke, Rameshwar S.;
Kharkar, Prashant S.;
Gaikwad, Vishwas;
Patil, Sambhaji;
Aware, Valmik

Publication type:

Article

Crocetin and related oxygen diffusion‐enhancing compounds: Review of chemical synthesis, pharmacology, clinical development, and novel therapeutic applications.

Published in:

Drug Development Research, 2021, v. 82, n. 7, p. 883, doi. 10.1002/ddr.21814

By:

Shah, Hriday M.;
Jain, Ashvi S.;
Joshi, Shreerang V.;
Kharkar, Prashant S.

Publication type:

Article

A novel series of substituted 1,2,3‐triazoles as cancer stem cell inhibitors: Synthesis and biological evaluation.

Published in:

Drug Development Research, 2021, v. 82, n. 1, p. 68, doi. 10.1002/ddr.21723

By:

Padhariya, Komal N.;
Athavale, Maithili;
Srivastava, Sangeeta;
Kharkar, Prashant S.

Publication type:

Article

An outlook on procedures of conjugating folate to (co)polymers and drugs for effective cancer targeting.

Published in:

Drug Development Research, 2020, v. 81, n. 7, p. 823, doi. 10.1002/ddr.21698

By:

Kharkar, Prashant S.;
Soni, Govind;
Rathod, Vaibhavi;
Shetty, Saritha;
Gupta, M. K.;
Yadav, Khushwant S.

Publication type:

Article

Substituted chloroacetamides as potential cancer stem cell inhibitors: Synthesis and biological evaluation.

Published in:

Drug Development Research, 2020, v. 81, n. 3, p. 356, doi. 10.1002/ddr.21628

By:

Padhariya, Komal N.;
Athavale, Maithili;
Srivastava, Sangeeta;
Kharkar, Prashant S.

Publication type:

Article

Novel analogs of sulfasalazine as system x<sub>c</sub><sup>−</sup> antiporter inhibitors: Insights from the molecular modeling studies.

Published in:

Drug Development Research, 2019, v. 80, n. 6, p. 758, doi. 10.1002/ddr.21557

By:

Patel, Dhavalkumar;
Kharkar, Prashant S.;
Gandhi, Neha S.;
Kaur, Ekjot;
Dutt, Shilpee;
Nandave, Mukesh

Publication type:

Article

Design, synthesis, and biological evaluation of Helicobacter pylori inosine 5′‐monophosphate dehydrogenase (HpIMPDH) inhibitors.

Published in:

Drug Development Research, 2019, v. 80, n. 1, p. 125, doi. 10.1002/ddr.21467

By:

Sahu, Niteshkumar U.;
Purushothaman, Gayathri;
Thiruvenkatam, Vijay;
Kharkar, Prashant S.

Publication type:

Article

Synthesis, molecular docking, and biological evaluation of novel 2-(3-chlorophenyl) quinoline-4-carboxamide derivatives as potent anti-breast cancer and antibacterial agents.

Published in:

Thai Journal of Pharmaceutical Sciences, 2021, v. 45, n. 1, p. 41

By:

Shinde, Kailas W.;
Kharkar, Prashant S.;
Shah, Chetan P.;
Rathod, Shrimant V.

Publication type:

Article

Virtual and experimental high-throughput screening (HTS) in search of novel inosine 5′-monophosphate dehydrogenase II (IMPDH II) inhibitors.

Published in:

Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 11, p. 1277, doi. 10.1007/s10822-012-9615-5

By:

Dunkern, Torsten;
Prabhu, Arati;
Kharkar, Prashant;
Goebel, Heike;
Rolser, Edith;
Burckhard-Boer, Waltraud;
Arumugam, Premkumar;
Makhija, Mahindra

Publication type:

Article

Attenuation of quorum sensing-regulated behaviour by Tinospora cordifolia extract & identification of its active constituents.

Published in:

Indian Journal of Medical Research, 2016, v. 144, n. 1, p. 92, doi. 10.4103/0971-5916.193295

By:

Gala, Viraj C.;
John, Nithya R.;
Bhagwat, Ashok M.;
Datar, Ajit G.;
Kharkar, Prashant S.;
Desai, Krutika B.

Publication type:

Article

Human Milk Oligosaccharides as Potential Antibiofilm Agents: A Review.

Published in:

Nutrients, 2022, v. 14, n. 23, p. 5112, doi. 10.3390/nu14235112

By:

Bhowmik, Ankurita;
Chunhavacharatorn, Phatchada;
Bhargav, Sharanya;
Malhotra, Akshit;
Sendrayakannan, Akalya;
Kharkar, Prashant S.;
Nirmal, Nilesh Prakash;
Chauhan, Ashwini

Publication type:

Article

Synthesis and Biological Characterization of (3 R,4 R)-4-(2-(Benzhydryloxy)ethyl)-1-(( R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and Its Stereoisomers for Activity toward Monoamine Transporters.

Published in:

ChemMedChem, 2009, v. 4, n. 7, p. 1075, doi. 10.1002/cmdc.200900085

By:

Kharkar, Prashant S.;
Batman, Angela M.;
Zhen, Juan;
Beardsley, Patrick M.;
Reith, Maarten E. A.;
Dutta, Aloke K.

Publication type:

Article

In‐silico identification of small molecules targeting H‐Ras and in‐vitro cytotoxicity with caspase‐mediated apoptosis in carcinoma cells.

Published in:

Journal of Cellular Biochemistry, 2019, v. 120, n. 4, p. 5519, doi. 10.1002/jcb.27836

By:

Damani Shah, Hetal;
Saranath, Dhananjaya;
Das, Soma;
Kharkar, Prashant;
Karande, Anjali

Publication type:

Article

In‐silico identification of small molecules targeting H‐Ras and in‐vitro cytotoxicity with caspase‐mediated apoptosis in carcinoma cells.

Published in:

Journal of Cellular Biochemistry, 2019, v. 120, n. 4, p. 5519, doi. 10.1002/jcb.27836

By:

Damani Shah, Hetal;
Saranath, Dhananjaya;
Das, Soma;
Kharkar, Prashant;
Karande, Anjali

Publication type:

Article

Three-dimensional quantitative structure-activity relationship (3D QSAR) and pharmacophore elucidation of tetrahydropyran derivatives as serotonin and norepinephrine transporter inhibitors.

Published in:

Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 1, p. 1, doi. 10.1007/s10822-007-9146-7

By:

Kharkar, Prashant S.;
Reith, Maarten E. A.;
Dutta, Aloke K.

Publication type:

Article

Anxiolytic activity of Psidium guajava in mice subjected to chronic restraint stress and effect on neurotransmitters in brain.

Published in:

Phytotherapy Research, 2021, v. 35, n. 3, p. 1399, doi. 10.1002/ptr.6900

By:

Sahoo, Swati;
Kharkar, Prashant S.;
Sahu, Niteshkumar U.;
S., Brijesh

Publication type:

Article

Newer human inosine 5′-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 972, doi. 10.1080/14756366.2018.1474211

By:

Shah, Chetan P.;
Kharkar, Prashant S.

Publication type:

Article

Inhibition of carbonic anhydrase isoforms I, II, IX and XII with Schiff’s bases incorporating iminoureido moieties.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2015, v. 30, n. 6, p. 901, doi. 10.3109/14756366.2014.986118

By:

Singasane, Namrata;
Kharkar, Prashant S.;
Ceruso, Mariangela;
Supuran, Claudiu T.;
Toraskar, Mrunmayee P.

Publication type:

Article

Design, synthesis and biological evaluation of novel inosine 5′-monophosphate dehydrogenase (IMPDH) inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2014, v. 29, n. 3, p. 408, doi. 10.3109/14756366.2013.793184

By:

Dunkern, Torsten;
Chavan, Sunil;
Bankar, Digambar;
Patil, Anuja;
Kulkarni, Pritee;
Kharkar, Prashant S.;
Prabhu, Arati;
Goebel, Heike;
Rolser, Edith;
Burckhard-Boer, Waltraud;
Arumugam, Premkumar;
Makhija, Mahindra T.

Publication type:

Article

Molecular Insights into Coumarin Analogues as Antimicrobial Agents: Recent Developments in Drug Discovery.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 5, p. 566, doi. 10.3390/antibiotics11050566

By:

Cheke, Rameshwar S.;
Patel, Harun M.;
Patil, Vaishali M.;
Ansari, Iqrar Ahmad;
Ambhore, Jaya P.;
Shinde, Sachin D.;
Kadri, Adel;
Snoussi, Mejdi;
Adnan, Mohd;
Kharkar, Prashant S.;
Pasupuleti, Visweswara Rao;
Deshmukh, Prashant K.

Publication type:

Article

Retraction Note: Extremely active Nano-formulation of Resveratrol (XAR™) attenuates and reverses chemotherapy-induced damage in mice ovaries and testes.

Published in:

2023

By:

Chhabria, Sagar;
Takle, Vaishnavi;
Sharma, Nripen;
Kharkar, Prashant;
Pansare, Kshama;
Tripathi, Anish;
Tripathi, Ashish;
Bhartiya, Deepa

Publication type:

Correction Notice

Extremely Active Nano-formulation of Resveratrol (XAR™) attenuates and reverses chemotherapy-induced damage in mice ovaries and testes.

Published in:

Journal of Ovarian Research, 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13048-022-01043-8

By:

Chhabria, Sagar;
Takle, Vaishnavi;
Sharma, Nripen;
Kharkar, Prashant;
Pansare, Kshama;
Tripathi, Anish;
Tripathi, Ashish;
Bhartiya, Deepa

Publication type:

Article

Extremely Active Nano-formulation of Resveratrol (XAR™) attenuates and reverses chemotherapy-induced damage in mice ovaries and testes.

Published in:

Journal of Ovarian Research, 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13048-022-01043-8

By:

Chhabria, Sagar;
Takle, Vaishnavi;
Sharma, Nripen;
Kharkar, Prashant;
Pansare, Kshama;
Tripathi, Anish;
Tripathi, Ashish;
Bhartiya, Deepa

Publication type:

Article

Cancer stem cell (CSC) inhibitors: a review of recent patents (2012-2015).

Published in:

Expert Opinion on Therapeutic Patents, 2017, v. 27, n. 7, p. 753, doi. 10.1080/13543776.2017.1325465

By:

Kharkar, Prashant S.

Publication type:

Article

In situ allicin generation using targeted alliinase delivery for inhibition of MIA PaCa-2 cells via epigenetic changes, oxidative stress and cyclin-dependent kinase inhibitor (CDKI) expression.

Published in:

Apoptosis, 2015, v. 20, n. 10, p. 1388, doi. 10.1007/s10495-015-1159-4

By:

Chhabria, Sagar;
Akbarsha, Mohammad;
Li, Albert;
Kharkar, Prashant;
Desai, Krutika

Publication type:

Article

Egg White Protein Carrier-Assisted Development of Solid Dispersion for Improved Aqueous Solubility and Permeability of Poorly Water Soluble Hydrochlorothiazide.

Published in:

AAPS PharmSciTech, 2021, v. 22, n. 3, p. 1, doi. 10.1208/s12249-021-01967-2

By:

Telange, Darshan R.;
Jain, Shirish P.;
Pethe, Anil M.;
Kharkar, Prashant S.

Publication type:

Article

Advancing quinoxaline chemistry: Sustainable and green synthesis using L-arabinose as a catalyst.

Published in:

Synthetic Communications, 2024, v. 54, n. 23, p. 2024, doi. 10.1080/00397911.2024.2419861

By:

Detke, Sandip J.;
Karwande, Anuja D.;
Ponugoti, Sai Srinivas;
Joshi, Shreerang V.;
Kharkar, Prashant S.

Publication type:

Article

Organocatalyzed ipso hydroxylation of aryl boronic acids in aqueous medium: A metal free approach.

Published in:

Synthetic Communications, 2023, v. 53, n. 12, p. 893, doi. 10.1080/00397911.2023.2203826

By:

Ponugoti, Sai Srinivas;
Vibuthe, Rutuja S.;
Detke, Sandip J.;
Kharkar, Prashant S.;
Joshi, Shreerang V.

Publication type:

Article

Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.

Published in:

Journal of Neurochemistry, 2008, v. 107, n. 4, p. 928, doi. 10.1111/j.1471-4159.2008.05667.x

By:

Schmitt, Kyle C.;
Zhen, Juan;
Kharkar, Prashant;
Mishra, Manoj;
Nianhang Chen;
Dutta, Aloke K.;
Reith, Maarten E. A.

Publication type:

Article

A Concise Analytical Profile of Efavirenz: Analytical Methodologies.

Published in:

2022

By:

Ambhore, Jaya P.;
Chaudhari, Suraj R.;
Cheke, Rameshwar S.;
Kharkar, Prashant S.

Publication type:

Literature Review