Works by Kharas, Michael G.

Results: 27

Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65905

By:

Sumiko Takao;
Forbes, Lauren;
Masahiro Uni;
Shuyuan Cheng;
Bello Pineda, Jose Mario;
Yusuke Tarumoto;
Cifani, Paolo;
Minuesa, Gerard;
Chen, Celine;
Kharas, Michael G.;
Bradley, Robert K.;
Vakoc, Christopher R.;
Koche, Richard P.;
Kentsis, Alex

Publication type:

Article

Peptidomimetic blockade of MYB in acute myeloid leukemia.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02618-6

By:

Minuesa, Gerard;
Brown, Fiona;
Kharas, Michael G.;
Still, Eric;
Ramaswamy, Kavitha;
Kentsis, Alex;
Forbes, Lauren;
Armstrong, Scott A.;
Gindin, Tatyana;
Koche, Richard;
Krivtsov, Andrei V.;
Knoechel, Birgit;
de Stanchina, Elisa

Publication type:

Article

Author Correction: ChromaFold predicts the 3D contact map from single-cell chromatin accessibility.

Published in:

2025

By:

Gao, Vianne R.;
Yang, Rui;
Das, Arnav;
Luo, Renhe;
Luo, Hanzhi;
McNally, Dylan R.;
Karagiannidis, Ioannis;
Rivas, Martin A.;
Wang, Zhong-Min;
Barisic, Darko;
Karbalayghareh, Alireza;
Wong, Wilfred;
Zhan, Yingqian A.;
Chin, Christopher R.;
Noble, William S.;
Bilmes, Jeff A.;
Apostolou, Effie;
Kharas, Michael G.;
Béguelin, Wendy;
Viny, Aaron D.

Publication type:

Correction Notice

ChromaFold predicts the 3D contact map from single-cell chromatin accessibility.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53628-0

By:

Gao, Vianne R.;
Yang, Rui;
Das, Arnav;
Luo, Renhe;
Luo, Hanzhi;
McNally, Dylan R.;
Karagiannidis, Ioannis;
Rivas, Martin A.;
Wang, Zhong-Min;
Barisic, Darko;
Karbalayghareh, Alireza;
Wong, Wilfred;
Zhan, Yingqian A.;
Chin, Christopher R.;
Noble, William S.;
Bilmes, Jeff A.;
Apostolou, Effie;
Kharas, Michael G.;
Béguelin, Wendy;
Viny, Aaron D.

Publication type:

Article

CT-080: A Tumor-Agnostic TCR-Mimic CAR-T cell Specific for NDC80 Targets Multiple Hematological Malignancies.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S447, doi. 10.1016/S2152-2650(21)01994-7

By:

Klatt, Martin G.;
Tao Dao;
Zhiyuan Yang;
Jianying Liu;
Sung Soo Mun;
Dacek, Megan M.;
Hanzhi Luo;
Gardner, Thomas J.;
Bourne, Christopher;
Leila Peraro;
Aretz, Zita E. H.;
Korontsvit, Tanya;
Kharas, Michael G.;
Cheng Liu;
Scheinberg, David A.

Publication type:

Article

Poster: CT-080: A Tumor-Agnostic TCR-Mimic CAR-T cell Specific for NDC80 Targets Multiple Hematological Malignancies.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S257, doi. 10.1016/S2152-2650(21)01621-9

By:

Klatt, Martin G.;
Tao Dao;
Zhiyuan Yang;
Jianying Liu;
Sung Soo Mun;
Dacek, Megan M.;
Hanzhi Luo;
Gardner, Thomas J.;
Bourne, Christopher;
Peraro, Leila;
Aretz, Zita E.H.;
Korontsvit, Tanya;
Kharas, Michael G.;
Liu, Cheng;
Scheinberg, David A.

Publication type:

Article

Oral Abstract: CT-080: A Tumor-Agnostic TCR-Mimic CAR-T cell Specific for NDC80 Targets Multiple Hematological Malignancies.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S204, doi. 10.1016/S2152-2650(21)01280-5

By:

Klatt, Martin G.;
Dao, Tao;
Yang, Zhiyuan;
Liu, Jianying;
Mun, Sung Soo;
Dacek, Megan M.;
Luo, Hanzhi;
Gardner, Thomas J.;
Bourne, Christopher;
Peraro, Leila;
Aretz, Zita E.H.;
Korontsvit, Tanya;
Kharas, Michael G.;
Liu, Cheng;
Scheinberg, David A.

Publication type:

Article

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia.

Published in:

Nature Medicine, 2010, v. 16, n. 8, p. 903, doi. 10.1038/nm.2187

By:

Kharas, Michael G.;
Lengner, Christopher J.;
Al-Shahrour, Fatima;
Bullinger, Lars;
Ball, Brian;
Zaidi, Samir;
Morgan, Kelly;
Tam, Winnie;
Paktinat, Mahnaz;
Okabe, Rachel;
Gozo, Maricel;
Einhorn, William;
Lane, Steven W.;
Scholl, Claudia;
Fröhling, Stefan;
Fleming, Mark;
Ebert, Benjamin L.;
Gilliland, D. Gary;
Jaenisch, Rudolf;
Daley, George Q.

Publication type:

Article

Emerging links between m<sup>6</sup>A and misregulated mRNA methylation in cancer.

Published in:

Genome Medicine, 2017, v. 9, p. 1, doi. 10.1186/s13073-016-0395-8

By:

Jaffrey, Samie R.;
Kharas, Michael G.

Publication type:

Article

The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease.

Published in:

Journal of Hematology & Oncology, 2014, v. 7, n. 1, p. 2, doi. 10.1186/1756-8722-7-45

By:

Gustafsson, Karin;
Jamalpour, Maria;
Trinh, Camilla;
Kharas, Michael G.;
Welsh, Michael

Publication type:

Article

Msi RNA-bin ding proteins control reserve intestinal stem cell quiescence.

Published in:

Journal of Cell Biology, 2016, v. 215, n. 3, p. 401, doi. 10.1083/jcb.201604119

By:

Ning Li;
Nakauka-Ddamba, Angela;
Davidow, Kimberly;
Schoenberger, Jenna;
Yousefi, Maryam;
Shan Wang;
Lengner, Christopher J.;
Zhengquan Yu;
Jensen, Shane T.;
Kharas, Michael G.

Publication type:

Article

KLF4 is a FOXO target gene that suppresses B cell proliferation.

Published in:

International Immunology, 2008, v. 20, n. 5, p. 671, doi. 10.1093/intimm/dxn024

By:

Isharat Yusuf;
Michael G. Kharas;
Jing Chen;
Raechel Q. Peralta;
Autumn Maruniak;
Pratibha Sareen;
Vincent W. Yang;
Klaus H. Kaestner;
David A. Fruman

Publication type:

Article

Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.

Published in:

Nature Communications, 2015, v. 6, n. 3, p. 6517, doi. 10.1038/ncomms7517

By:

Wang, Shan;
Li, Ning;
Yousefi, Maryam;
Nakauka-Ddamba, Angela;
Li, Fan;
Parada, Kimberly;
Rao, Shilpa;
Minuesa, Gerard;
Katz, Yarden;
Gregory, Brian D.;
Kharas, Michael G.;
Yu, Zhengquan;
Lengner, Christopher J.

Publication type:

Article

Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi.

Published in:

Endocrinology, 2021, v. 162, n. 3, p. 1, doi. 10.1210/endocr/bqaa245

By:

Allensworth-James, Melody;
Banik, Jewel;
Odle, Angela;
Hardy, Linda;
Lagasse, Alex;
Moreira, Ana Rita Silva;
Bird, Jordan;
Thomas, Christian L;
Avaritt, Nathan;
Kharas, Michael G;
Lengner, Christopher J;
Byrum, Stephanie D;
MacNicol, Melanie C;
Childs, Gwen V;
MacNicol, Angus M

Publication type:

Article

RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18022-6

By:

Montalbano, Mauro;
McAllen, Salome;
Puangmalai, Nicha;
Sengupta, Urmi;
Bhatt, Nemil;
Johnson, Omar D.;
Kharas, Michael G.;
Kayed, Rakez

Publication type:

Article

HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15814-8

By:

Nguyen, Diu T. T.;
Lu, Yuheng;
Chu, Karen L.;
Yang, Xuejing;
Park, Sun-Mi;
Choo, Zi-Ning;
Chin, Christopher R.;
Prieto, Camila;
Schurer, Alexandra;
Barin, Ersilia;
Savino, Angela M.;
Gourkanti, Saroj;
Patel, Payal;
Vu, Ly P.;
Leslie, Christina S.;
Kharas, Michael G.

Publication type:

Article

Gamma-Tocotrienol loaded liposomes as radioprotection from hematopoietic side effects caused by radiotherapeutic drugs.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 12, p. 1, doi. 10.2967/jnumed.120.244681

By:

Sang-gyu Lee;
Kalidindi, Teja Muralidhar;
Hanzhi Lou;
Gangangari, Kishore;
Punzalan, Blesida;
Bitton, Ariana;
Lee, Casey J.;
Vargas, Hebert A.;
Park, Soobin;
Bodei, Lisa;
Kharas, Michael G.;
Singh, Vijay K.;
Pillarsetty, Naga Vara Kishore;
Larson, Steven M.

Publication type:

Article

Gamma-Tocotrienol loaded liposomes as radioprotection from hematopoietic side effects caused by radiotherapeutic drugs.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 11, p. 1, doi. 10.2967/jnumed.120.244681

By:

Sang-gyu Lee;
Kalidindi, Teja Muralidhar;
Hanzhi Lou;
Gangangari, Kishore;
Punzalan, Blesida;
Bitton, Ariana;
Lee, Casey J.;
Vargas, Hebert A.;
Park, Soobin;
Bodei, Lisa;
Kharas, Michael G.;
Singh, Vijay K.;
Pillarsetty, Naga Vara Kishore;
Larson, Steven M.

Publication type:

Article

Gamma-Tocotrienol loaded liposomes as radioprotection from hematopoietic side effects caused by radiotherapeutic drugs.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 10, p. 1, doi. 10.2967/jnumed.120.244681

By:

Sanggyu Lee;
Kalidindi, Teja Muralidhar;
Hanzhi Lou;
Gangangari, Kishore;
Punzalan, Blesida;
Bitton, Ariana;
Lee, Casey J.;
Vargas, Hebert A.;
Park, Soobin;
Bodei, Lisa;
Kharas, Michael G.;
Singh, Vijay K.;
Kishore Pillarsetty, Naga Vara;
Larson, Steven M.

Publication type:

Article

Gamma-Tocotrienol loaded liposomes as radioprotection from hematopoietic side effects caused by radiotherapeutic drugs.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 9, p. 1, doi. 10.2967/jnumed.120.244681

By:

Sang-gyu Lee;
Kalidindi, Teja Muralidhar;
Hanzhi Lou;
Gangangari, Kishore;
Punzalan, Blesida;
Bitton, Ariana;
Lee, Casey J.;
Vargas, Hebert A.;
Park, Soobin;
Bodei, Lisa;
Kharas, Michael G.;
Singh, Vijay K.;
Kishore Pillarsetty, Naga Vara;
Larson, Steven M.

Publication type:

Article

High-speed automatic characterization of rare events in flow cytometric data.

Published in:

PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0228651

By:

Qi, Yuan;
Fang, Youhan;
Sinclair, David R.;
Guo, Shangqin;
Alberich-Jorda, Meritxell;
Lu, Jun;
Tenen, Daniel G.;
Kharas, Michael G.;
Pyne, Saumyadipta

Publication type:

Article

Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1<sup>G93A</sup> astrocytes.

Published in:

Autophagy, 2021, v. 17, n. 12, p. 4029, doi. 10.1080/15548627.2021.1899682

By:

Granatiero, Veronica;
Sayles, Nicole M.;
Savino, Angela M.;
Konrad, Csaba;
Kharas, Michael G.;
Kawamata, Hibiki;
Manfredi, Giovanni

Publication type:

Article

MUSASHI-2 duels in myelodysplastic syndromes.

Published in:

Cell Cycle, 2016, v. 15, n. 14, p. 1799, doi. 10.1080/15384101.2016.1176401

By:

Ho, Tzu-Chieh;
Taggart, James;
Kharas, Michael G.

Publication type:

Article

Akt.

Published in:

Cell Cycle, 2010, v. 9, n. 7, p. 1223, doi. 10.4161/cc.9.7.11362

By:

Kharas, Michael G.;
Gritsman, Kira

Publication type:

Article

Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.

Published in:

2017

By:

Kharas, Michael G;
Janes, Matthew R;
Scarfone, Vanessa M;
Lilly, Michael B;
Knight, Zachary A;
Shokat, Kevan M;
Fruman, David A

Publication type:

journal article

Musashi2 sustains the mixed-lineage leukemia--driven stem cell regulatory program.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 3, p. 1286, doi. 10.1172/JCI78440

By:

Sun-Mi Park;
Gönen, Mithat;
Ly Vu;
Minuesa, Gerard;
Tivnan, Patrick;
Barlowe, Trevor S.;
Taggart, James;
Yuheng Lu;
Deering, Raquel P.;
Nir Hacohen;
Figueroa, Maria E.;
Paietta, Elisabeth;
Fernandez, Hugo F.;
Tallman, Martin S.;
Melnick, Ari;
Levine, Ross;
Leslie, Christina;
Lengner, Christopher J.;
Kharas, Michael G.

Publication type:

Article

Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.

Published in:

2008

By:

Kharas, Michael G.;
Janes, Matthew R.;
Scarfone, Vanessa M.;
Lilly, Michael B.;
Knight, Zachary A.;
Shokat, Kevan M.;
Fruman, David A.

Publication type:

journal article