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Acute cytomegalovirus infection modulates the intestinal microbiota and targets intestinal epithelial cells.
Published in:
European Journal of Immunology, 2023, v. 53, n. 2, p. 1, doi. 10.1002/eji.202249940
By:
- Le‐Trilling, Vu Thuy Khanh;
- Ebel, Jana‐Fabienne;
- Baier, Franziska;
- Wohlgemuth, Kerstin;
- Pfeifer, Kai Robin;
- Mookhoek, Aart;
- Krebs, Philippe;
- Determann, Madita;
- Katschinski, Benjamin;
- Adamczyk, Alexandra;
- Lange, Erik;
- Klopfleisch, Robert;
- Lange, Christian M.;
- Sokolova, Viktoriya;
- Trilling, Mirko;
- Westendorf, Astrid M.
Publication type:
Article
Prophylactic and therapeutic HBV vaccination by an HBs‐expressing cytomegalovirus vector lacking an interferon antagonist in mice.
Published in:
European Journal of Immunology, 2021, v. 51, n. 2, p. 393, doi. 10.1002/eji.202048780
By:
- Huang, Hongming;
- Rückborn, Meike;
- Le‐Trilling, Vu Thuy Khanh;
- Zhu, Dan;
- Yang, Shangqing;
- Zhou, Wenqing;
- Yang, Xuecheng;
- Feng, Xuemei;
- Lu, Yinping;
- Lu, Mengji;
- Dittmer, Ulf;
- Yang, Dongliang;
- Trilling, Mirko;
- Liu, Jia
Publication type:
Article
Cellular Cullin RING Ubiquitin Ligases: Druggable Host Dependency Factors of Cytomegaloviruses.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 7, p. 1636, doi. 10.3390/ijms20071636
By:
- Becker, Tanja;
- Le-Trilling, Vu Thuy Khanh;
- Trilling, Mirko
Publication type:
Article
IL-12-producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansion.
Published in:
2014
By:
- Rölle, Alexander;
- Pollmann, Julia;
- Ewen, Eva-Maria;
- Le, Vu Thuy Khanh;
- Halenius, Anne;
- Hengel, Hartmut;
- Cerwenka, Adelheid
Publication type:
Journal Article
IL-12-producing monocytes and HLA-E control HCMV-driven NKC2C<sup>+</sup> NK cell expansion.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 12, p. 5305, doi. 10.1172/JCI77440
By:
- Rölle, Alexander;
- Pollmann, Julia;
- Ewen, Eva-Marla;
- Vu Thuy Khanh Le;
- Halenius, Anne;
- Hengel, Hartmut;
- Cerwenka, Adelheid
Publication type:
Article
Discrepancy between frequent occurrence of COVID‐19‐like symptoms and low seroconversion rates among healthcare workers.
Published in:
Journal of Medical Virology, 2022, v. 94, n. 3, p. 951, doi. 10.1002/jmv.27385
By:
- Dehnen, Dorothea;
- Dehnen, Katja;
- Trilling, Mirko;
- Fiedler, Melanie;
- Drexler, Julia;
- Goralski, Marcel;
- Le‐Trilling, Vu Thuy Khanh;
- Schöler, Lara;
- Jöckel, Karl‐Heinz;
- Heßbrügge, Martina
Publication type:
Article
Over 90% of clinical swabs used for SARS‐CoV‐2 diagnostics contain sufficient nucleic acid concentrations.
Published in:
Journal of Medical Virology, 2021, v. 93, n. 5, p. 2848, doi. 10.1002/jmv.26706
By:
- Klingen, Robin L.;
- Katschinski, Benjamin;
- Anastasiou, Olympia E.;
- Ross, R. Stefan;
- Dittmer, Ulf;
- Le‐Trilling, Vu Thuy Khanh;
- Trilling, Mirko
Publication type:
Article
Human cytomegalovirus antagonizes activation of Fcg receptors by distinct and synergizing modes of IgG manipulation.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.63877
By:
- Kolb, Philipp;
- Hoffmann, Katja;
- Sievert, Annika;
- Reinhard, Henrike;
- Merce-Maldonado, Eva;
- Khanh Le-Trilling, Vu Thuy;
- Halenius, Anne;
- ̈tle, Dominique Gu;
- Hengel, Hartmut
Publication type:
Article
Structural mechanism of CRL4‐instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor.
Published in:
EMBO Journal, 2023, v. 42, n. 5, p. 1, doi. 10.15252/embj.2022112351
By:
- Le‐Trilling, Vu Thuy Khanh;
- Banchenko, Sofia;
- Paydar, Darius;
- Leipe, Pia Madeleine;
- Binting, Lukas;
- Lauer, Simon;
- Graziadei, Andrea;
- Klingen, Robin;
- Gotthold, Christine;
- Bürger, Jörg;
- Bracht, Thilo;
- Sitek, Barbara;
- Jan Lebbink, Robert;
- Malyshkina, Anna;
- Mielke, Thorsten;
- Rappsilber, Juri;
- Spahn, Christian MT;
- Voigt, Sebastian;
- Trilling, Mirko;
- Schwefel, David
Publication type:
Article
Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitro.
Published in:
BMC Biology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12915-022-01468-z
By:
- Le-Trilling, Vu Thuy Khanh;
- Mennerich, Denise;
- Schuler, Corinna;
- Sakson, Roman;
- Lill, Julia K.;
- Kasarla, Siva Swapna;
- Kopczynski, Dominik;
- Loroch, Stefan;
- Flores-Martinez, Yulia;
- Katschinski, Benjamin;
- Wohlgemuth, Kerstin;
- Gunzer, Matthias;
- Meyer, Folker;
- Phapale, Prasad;
- Dittmer, Ulf;
- Sickmann, Albert;
- Trilling, Mirko
Publication type:
Article
Broad and potent antiviral activity of the NAE inhibitor MLN4924.
Published in:
Scientific Reports, 2016, p. 19977, doi. 10.1038/srep19977
By:
- Le-Trilling, Vu Thuy Khanh;
- Megger, Dominik A.;
- Katschinski, Benjamin;
- Landsberg, Christine D.;
- Rückborn, Meike U.;
- Tao, Sha;
- Krawczyk, Adalbert;
- Bayer, Wibke;
- Drexler, Ingo;
- Tenbusch, Matthias;
- Sitek, Barbara;
- Trilling, Mirko
Publication type:
Article
The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant Recipients.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00917
By:
- Rohn, Hana;
- Tomoya Michita, Rafael;
- Schwich, Esther;
- Dolff, Sebastian;
- Gäckler, Anja;
- Trilling, Mirko;
- Le-Trilling, Vu Thuy Khanh;
- Wilde, Benjamin;
- Korth, Johannes;
- Heinemann, Falko M.;
- Horn, Peter A.;
- Kribben, Andreas;
- Witzke, Oliver;
- Rebmann, Vera
Publication type:
Article
Exploitation of Herpesviral Transactivation Allows Quantitative Reporter Gene-Based Assessment of Virus Entry and Neutralization.
Published in:
PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0014532
By:
- Reinhard, Henrike;
- Le, Vu Thuy Khanh;
- Ohlin, Mats;
- Hengel, Hartmut;
- Trilling, Mirko
Publication type:
Article
The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing.
Published in:
PLoS Pathogens, 2021, v. 17, n. 5, p. 1, doi. 10.1371/journal.ppat.1008807
By:
- Seidel, Einat;
- Dassa, Liat;
- Schuler, Corinna;
- Oiknine-Djian, Esther;
- Wolf, Dana G.;
- Le-Trilling, Vu Thuy Khanh;
- Mandelboim, Ofer
Publication type:
Article
UnCoVar: a reproducible and scalable workflow for transparent and robust virus variant calling and lineage assignment using SARS-CoV-2 as an example.
Published in:
BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10539-0
By:
- Thomas, Alexander;
- Battenfeld, Thomas;
- Kraiselburd, Ivana;
- Anastasiou, Olympia;
- Dittmer, Ulf;
- Dörr, Ann-Kathrin;
- Dörr, Adrian;
- Elsner, Carina;
- Gosch, Jule;
- Le-Trilling, Vu Thuy Khanh;
- Magin, Simon;
- Scholtysik, René;
- Yilmaz, Pelin;
- Trilling, Mirko;
- Schöler, Lara;
- Köster, Johannes;
- Meyer, Folker
Publication type:
Article
Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus.
Published in:
NPJ Vaccines, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41541-023-00602-4
By:
- Le-Trilling, Vu Thuy Khanh;
- Jagnjić, Andreja;
- Brizić, Ilija;
- Eilbrecht, Mareike;
- Wohlgemuth, Kerstin;
- Rožmanić, Carmen;
- Herdman, Alan;
- Hoffmann, Katja;
- Westendorf, Astrid M.;
- Hengel, Hartmut;
- Jonjić, Stipan;
- Trilling, Mirko
Publication type:
Article
Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.85560
By:
- Gerke, Carolin;
- Bauersfeld, Liane;
- Schirmeister, Ivo;
- Mireisz, Chiara Noemi-Marie;
- Oberhardt, Valerie;
- Mery, Lea;
- Di Wu;
- Jürges, Christopher Sebastian;
- Spaapen, Robbert M.;
- Mussolino, Claudio;
- Vu Thuy Khanh Le-Trilling;
- Trilling, Mirko;
- Dölken, Lars;
- Paster, Wolfgang;
- Erhard, Florian;
- Hofmann, Maike;
- Schlosser, Andreas;
- Hengel, Hartmut;
- Momburg, Frank;
- Halenius, Anne
Publication type:
Article
Persistence of KIR<sup>neg</sup> NK cells after haploidentical hematopoietic stem cell transplantation protects from human cytomegalovirus infection/reactivation.
Published in:
Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2023.1266051
By:
- Di Vito, Clara;
- Coianiz, Nicolò;
- Calvi, Michela;
- Terzoli, Sara;
- Zaghi, Elisa;
- Puccio, Simone;
- Frigo, Alessandro;
- Mariotti, Jacopo;
- De Philippis, Chiara;
- Mannina, Daniele;
- Sarina, Barbara;
- Mineri, Rossana;
- Vu Thuy Khanh Le-Trilling;
- Trilling, Mirko;
- Castagna, Luca;
- Bramanti, Stefania;
- Santoro, Armando;
- Mavilio, Domenico
Publication type:
Article
Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation.
Published in:
Frontiers in Immunology, 2023, v. 14, p. 01, doi. 10.3389/fimmu.2023.1170300
By:
- Vu Thuy Khanh Le-Trilling;
- Maaßen, Fabienne;
- Katschinski, Benjamin;
- Hengel, Hartmut;
- Trilling, Mirko
Publication type:
Article
Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy.
Published in:
2020
By:
- Such, Lina;
- Zhao, Fang;
- Liu, Derek;
- Thier, Beatrice;
- Khanh Le-Trilling, Vu Thuy;
- Sucker, Antje;
- Coch, Christoph;
- Pieper, Natalia;
- Howe, Sebastian;
- Bhat, Hilal;
- Kalkavan, Halime;
- Ritter, Cathrin;
- Brinkhaus, Robin;
- Ugurel, Selma;
- Köster, Johannes;
- Seifert, Ulrike;
- Dittmer, Ulf;
- Schuler, Martin;
- Lang, Karl S.;
- Kufer, Thomas A.
Publication type:
journal article
Occurrence of COVID-19 Symptoms During SARS-CoV-2 Infection Defines Waning of Humoral Immunity.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.722027
By:
- Wu, Jun;
- Liang, Bo-Yun;
- Fang, Yao-Hui;
- Wang, Hua;
- Yang, Xiao-Li;
- Shen, Shu;
- Chen, Liang-Kai;
- Li, Su-Meng;
- Lu, Si-Hong;
- Xiang, Tian-Dan;
- Liu, Jia;
- Le-Trilling, Vu Thuy Khanh;
- Lu, Meng-Ji;
- Yang, Dong-Liang;
- Deng, Fei;
- Dittmer, Ulf;
- Trilling, Mirko;
- Zheng, Xin
Publication type:
Article
A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral Compounds.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.573526
By:
- Schöler, Lara;
- Le-Trilling, Vu Thuy Khanh;
- Eilbrecht, Mareike;
- Mennerich, Denise;
- Anastasiou, Olympia E.;
- Krawczyk, Adalbert;
- Herrmann, Anke;
- Dittmer, Ulf;
- Trilling, Mirko
Publication type:
Article
Turmeric Root and Its Bioactive Ingredient Curcumin Effectively Neutralize SARS-CoV-2 In Vitro.
Published in:
Viruses (1999-4915), 2021, v. 13, n. 10, p. 1914, doi. 10.3390/v13101914
By:
- Bormann, Maren;
- Alt, Mira;
- Schipper, Leonie;
- van de Sand, Lukas;
- Le-Trilling, Vu Thuy Khanh;
- Rink, Lydia;
- Heinen, Natalie;
- Madel, Rabea Julia;
- Otte, Mona;
- Wuensch, Korbinian;
- Heilingloh, Christiane Silke;
- Mueller, Thorsten;
- Dittmer, Ulf;
- Elsner, Carina;
- Pfaender, Stephanie;
- Trilling, Mirko;
- Witzke, Oliver;
- Krawczyk, Adalbert
Publication type:
Article
Nedd8-Activating Enzyme Is a Druggable Host Dependency Factor of Human and Mouse Cytomegalovirus.
Published in:
Viruses (1999-4915), 2021, v. 13, n. 8, p. 1610, doi. 10.3390/v13081610
By:
- Flores-Martínez, Yulia Alejandra;
- Le-Trilling, Vu Thuy Khanh;
- Trilling, Mirko
Publication type:
Article
The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions.
Published in:
PLoS Pathogens, 2015, v. 11, n. 11, p. 1, doi. 10.1371/journal.ppat.1005288
By:
- Tirosh, Osnat;
- Cohen, Yifat;
- Shitrit, Alina;
- Shani, Odem;
- Le-Trilling, Vu Thuy Khanh;
- Trilling, Mirko;
- Friedlander, Gilgi;
- Tanenbaum, Marvin;
- Stern-Ginossar, Noam
Publication type:
Article
Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and III.
Published in:
PLoS Pathogens, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.ppat.1004131
By:
- Corrales-Aguilar, Eugenia;
- Trilling, Mirko;
- Hunold, Katja;
- Fiedler, Manuela;
- Le, Vu Thuy Khanh;
- Reinhard, Henrike;
- Ehrhardt, Katrin;
- Mercé-Maldonado, Eva;
- Aliyev, Enver;
- Zimmermann, Albert;
- Johnson, David C.;
- Hengel, Hartmut
Publication type:
Article
MicroRNA Editing Facilitates Immune Elimination of HCMV Infected Cells.
Published in:
PLoS Pathogens, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.ppat.1003963
By:
- Nachmani, Daphna;
- Zimmermann, Albert;
- Oiknine Djian, Esther;
- Weisblum, Yiska;
- Livneh, Yoav;
- Khanh Le, Vu Thuy;
- Galun, Eithan;
- Horejsi, Vaclav;
- Isakov, Ofer;
- Shomron, Noam;
- Wolf, Dana G.;
- Hengel, Hartmut;
- Mandelboim, Ofer
Publication type:
Article
Identification of DNA-Damage DNA-Binding Protein 1 as a Conditional Essential Factor for Cytomegalovirus Replication in Interferon-γ-Stimulated Cells.
Published in:
PLoS Pathogens, 2011, v. 7, n. 6, p. 1, doi. 10.1371/journal.ppat.1002069
By:
- Trilling, Mirko;
- Le, Vu Thuy Khanh;
- Fiedler, Manuela;
- Zimmermann, Albert;
- Bleifuβ, Elke;
- Hengel, Hartmut
Publication type:
Article
Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01139
By:
- Megger, Dominik A.;
- Philipp, Jos;
- Le-Trilling, Vu Thuy Khanh;
- Sitek, Barbara;
- Trilling, Mirko
Publication type:
Article
Human Cytomegalovirus-lnduced Degradation of CYTIP Modulates Dendritic Cell Adhesion and Migration.
Published in:
Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00461
By:
- Grosche, Linda;
- Draßner, Christina;
- Mühl-Zürbes, Petra;
- Kamm, Lisa;
- Le-Trilling, Vu Thuy Khanh;
- Trilling, Mirko;
- Steinkasserer, Alexander;
- Heilingloh, Christiane S.
Publication type:
Article
Human Cytomegalovirus-Induced Degradation of CYTIP Modulates Dendritic Cell Adhesion and Migration.
Published in:
Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00461
By:
- Grosche, Linda;
- Draßner, Christina;
- Mühl-Zürbes, Petra;
- Kamm, Lisa;
- Vu Thuy Khanh Le-Trilling;
- Trilling, Mirko;
- Steinkasserer, Alexander;
- Heilingloh, Christiane S.
Publication type:
Article
Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early - Late Expressed Protein Required for Efficient Viral Replication.
Published in:
Frontiers in Cellular & Infection Microbiology, 2020, v. 10, p. 1, doi. 10.3389/fcimb.2020.00171
By:
- Eilbrecht, Mareike;
- Le-Trilling, Vu Thuy Khanh;
- Trilling, Mirko
Publication type:
Article
Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infection.
Published in:
PLoS Pathogens, 2019, v. 15, n. 9, p. 1, doi. 10.1371/journal.ppat.1008043
By:
- Bongard, Nadine;
- Le-Trilling, Vu Thuy Khanh;
- Malyshkina, Anna;
- Rückborn, Meike;
- Wohlgemuth, Kerstin;
- Wensing, Ina;
- Windmann, Sonja;
- Dittmer, Ulf;
- Trilling, Mirko;
- Bayer, Wibke
Publication type:
Article
HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11.
Published in:
PLoS Pathogens, 2019, v. 15, n. 9, p. 1, doi. 10.1371/journal.ppat.1008040
By:
- Zimmermann, Cosima;
- Kowalewski, Daniel;
- Bauersfeld, Liane;
- Hildenbrand, Andreas;
- Gerke, Carolin;
- Schwarzmüller, Magdalena;
- Le-Trilling, Vu Thuy Khanh;
- Stevanovic, Stefan;
- Hengel, Hartmut;
- Momburg, Frank;
- Halenius, Anne
Publication type:
Article
Establishment and clinical validation of an in-cell-ELISA-based assay for the rapid quantification of Rabies virus neutralizing antibodies.
Published in:
PLoS Neglected Tropical Diseases, 2022, v. 16, n. 5, p. 1, doi. 10.1371/journal.pntd.0010425
By:
- Schöler, Lara;
- Le-Trilling, Vu Thuy Khanh;
- Dittmer, Ulf;
- Fiedler, Melanie;
- Trilling, Mirko
Publication type:
Article
Mouse newborn cells allow highly productive mouse cytomegalovirus replication, constituting a novel convenient primary cell culture system.
Published in:
PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0174695
By:
- Le-Trilling, Vu Thuy Khanh;
- Trilling, Mirko
Publication type:
Article

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