Works by Kettunen, Johannes

Results: 61

Genome-wide association study indicates novel associations of annexin A13 to secretory and GAS2L2 with mucous otitis media.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-68781-1

By:

Bizaki-Vallaskangas, Argyro;
Rämö, Joel;
Sliz, Eeva;
Kivekäs, Ilkka;
Willberg, Tytti;
Saarentaus, Elmo;
Toppila-Salmi, Sanna;
Dietz, Aarno;
Haapaniemi, Teppo;
Hytönen, Vesa P.;
Toivola, Sari;
Palotie, Aarno;
Mäkitie, Antti;
Kettunen, Johannes

Publication type:

Article

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation.

Published in:

Genome Biology, 2017, v. 18, p. 1, doi. 10.1186/s13059-017-1279-y

By:

Nath, Artika P.;
Ritchie, Scott C.;
Byars, Sean G.;
Fearnley, Liam G.;
Havulinna, Aki S.;
Joensuu, Anni;
Kangas, Antti J.;
Soininen, Pasi;
Wennerström, Annika;
Milani, Lili;
Metspalu, Andres;
Männistö, Satu;
Würtz, Peter;
Kettunen, Johannes;
Raitoharju, Emma;
Kähönen, Mika;
Juonala, Markus;
Palotie, Aarno;
Ala-Korpela, Mika;
Ripatti, Samuli

Publication type:

Article

Genome‐wide association study of anterior uveitis.

Published in:

2025

By:

Koskimäki, Fredrika;
Ahokas, Oona;
Elnahas, Abdelrahman;
Reigo, Anu;
Reis, Kadri;
Esko, Tõnu;
Palta, Priit;
Leinonen, Sanna;
Kettunen, Johannes;
Liinamaa, Johanna;
Karjalainen, Minna;
Saarela, Ville

Publication type:

Abstract

Genome‐wide association study of anterior uveitis.

Published in:

2025

By:

Koskimäki, Fredrika;
Ahokas, Oona;
Consortium, FinnGen;
Team, Estonian Biobank Research;
Elnahas, Abdelrahman;
Reigo, Anu;
Reis, Kadri;
Esko, Tõnu;
Palta, Priit;
Leinonen, Sanna;
Kettunen, Johannes;
Liinamaa, Johanna;
Karjalainen, Minna;
Saarela, Ville

Publication type:

Abstract

Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality.

Published in:

PLoS ONE, 2019, v. 14, n. 10, p. 1, doi. 10.1371/journal.pone.0223692

By:

Ritchie, Scott C.;
Kettunen, Johannes;
Brozynska, Marta;
Nath, Artika P.;
Havulinna, Aki S.;
Männistö, Satu;
Perola, Markus;
Salomaa, Veikko;
Ala-Korpela, Mika;
Abraham, Gad;
Würtz, Peter;
Inouye, Michael

Publication type:

Article

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

Published in:

Nature Genetics, 2012, v. 44, n. 3, p. 269, doi. 10.1038/ng.1073

By:

Kettunen, Johannes;
Tukiainen, Taru;
Sarin, Antti-Pekka;
Ortega-Alonso, Alfredo;
Tikkanen, Emmi;
Lyytikäinen, Leo-Pekka;
Kangas, Antti J;
Soininen, Pasi;
Würtz, Peter;
Silander, Kaisa;
Dick, Danielle M;
Rose, Richard J;
Savolainen, Markku J;
Viikari, Jorma;
Kähönen, Mika;
Lehtimäki, Terho;
Pietiläinen, Kirsi H;
Inouye, Michael;
McCarthy, Mark I;
Jula, Antti

Publication type:

Article

Cell Specific eQTL Analysis without Sorting Cells.

Published in:

PLoS Genetics, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pgen.1005223

By:

Westra, Harm-Jan;
Arends, Danny;
Esko, Tõnu;
Peters, Marjolein J.;
Schurmann, Claudia;
Schramm, Katharina;
Kettunen, Johannes;
Yaghootkar, Hanieh;
Fairfax, Benjamin P.;
Andiappan, Anand Kumar;
Li, Yang;
Fu, Jingyuan;
Karjalainen, Juha;
Platteel, Mathieu;
Visschedijk, Marijn;
Weersma, Rinse K.;
Kasela, Silva;
Milani, Lili;
Tserel, Liina;
Peterson, Pärt

Publication type:

Article

Chromosome X-Wide Association Study Identifies Loci for Fasting Insulin and Height and Evidence for Incomplete Dosage Compensation.

Published in:

PLoS Genetics, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.pgen.1004127

By:

Tukiainen, Taru;
Pirinen, Matti;
Sarin, Antti-Pekka;
Ladenvall, Claes;
Kettunen, Johannes;
Lehtimäki, Terho;
Lokki, Marja-Liisa;
Perola, Markus;
Sinisalo, Juha;
Vlachopoulou, Efthymia;
Eriksson, Johan G.;
Groop, Leif;
Jula, Antti;
Järvelin, Marjo-Riitta;
Raitakari, Olli T.;
Salomaa, Veikko;
Ripatti, Samuli

Publication type:

Article

High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms.

Published in:

PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1004134

By:

Kurki, Mitja I.;
Gaál, Emília Ilona;
Kettunen, Johannes;
Lappalainen, Tuuli;
Menelaou, Androniki;
Anttila, Verneri;
van 't Hof, Femke N. G.;
von und zu Fraunberg, Mikael;
Helisalmi, Seppo;
Hiltunen, Mikko;
Lehto, Hanna;
Laakso, Aki;
Kivisaari, Riku;
Koivisto, Timo;
Ronkainen, Antti;
Rinne, Jaakko;
Kiemeney, Lambertus A. L.;
Vermeulen, Sita H.;
Kaunisto, Mari A.;
Eriksson, Johan G.

Publication type:

Article

Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis.

Published in:

PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002907

By:

Inouye, Michael;
Ripatti, Samuli;
Kettunen, Johannes;
Lyytikäinen, Leo-Pekka;
Oksala, Niku;
Laurila, Pirkka-Pekka;
Kangas, Antti J.;
Soininen, Pasi;
Savolainen, Markku J.;
Viikari, Jorma;
Kähönen, Mika;
Perola, Markus;
Salomaa, Veikko;
Raitakari, Olli;
Lehtimäki, Terho;
Taskinen, Marja-Riitta;
Järvelin, Marjo-Riitta;
Ala-Korpela, Mika;
Palotie, Aarno;
De Bakker, Paul I. W.

Publication type:

Article

Intracranial Aneurysm Risk Locus 5q23.2 Is Associated with Elevated Systolic Blood Pressure.

Published in:

PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002563

By:

Gaál, Emília Ilona;
Salo, Perttu;
Kristiansson, Kati;
Rehnström, Karola;
Kettunen, Johannes;
Sarin, Antti-Pekka;
¨, Mika Niemela;
Jula, Antti;
Raitakari, Olli T.;
Lehtimäki, Terho;
Eriksson, Johan G.;
Widen, Elisabeth;
nel, Murat Gu ¨;
Kurki, Mitja;
von und zu Fraunberg, Mikael;
Jääskeläinen, Juha E.;
Hernesniemi, Juha;
Järvelin, Marjo-Riitta;
Pouta, Anneli;
Newton-Cheh, Christopher

Publication type:

Article

Biomarker Profiling by Nuclear Magnetic Resonance Spectroscopy for the Prediction of All-Cause Mortality: An Observational Study of 17,345 Persons.

Published in:

PLoS Medicine, 2014, v. 11, n. 2, p. 1, doi. 10.1371/journal.pmed.1001606

By:

Fischer, Krista;
Kettunen, Johannes;
Würtz, Peter;
Haller, Toomas;
Havulinna, Aki S.;
Kangas, Antti J.;
Soininen, Pasi;
Esko, Tõnu;
Tammesoo, Mari-Liis;
Mägi, Reedik;
Smit, Steven;
Palotie, Aarno;
Ripatti, Samuli;
Salomaa, Veikko;
Ala-Korpela, Mika;
Perola, Markus;
Metspalu, Andres

Publication type:

Article

Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease.

Published in:

2019

By:

Qiong Jia;
Yi Han;
Pin Huang;
Woodward, Nicholas C.;
Gukasyan, Janet;
Kettunen, Johannes;
Ala-Korpela, Mika;
Anufrieva, Olga;
Qin Wang;
Perola, Markus;
Raitakari, Olli;
Lehtimäki, Terho;
Viikari, Jorma;
Järvelin, Marjo-Riitta;
Boehnke, Michael;
Laakso, Markku;
Mohlke, Karen L.;
Fiehn, Oliver;
Zeneng Wang;
Tang, W. H. Wilson

Publication type:

journal article

Genome-Wide Meta-Analysis of Sciatica in Finnish Population.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0163877

By:

Lemmelä, Susanna;
Solovieva, Svetlana;
Shiri, Rahman;
Benner, Christian;
Heliövaara, Markku;
Kettunen, Johannes;
Anttila, Verneri;
Ripatti, Samuli;
Perola, Markus;
Seppälä, Ilkka;
Juonala, Markus;
Kähönen, Mika;
Salomaa, Veikko;
Viikari, Jorma;
Raitakari, Olli T.;
Lehtimäki, Terho;
Palotie, Aarno;
Viikari-Juntura, Eira;
Husgafvel-Pursiainen, Kirsti

Publication type:

Article

The impact of low-frequency and rare variants on lipid levels.

Published in:

Nature Genetics, 2015, v. 47, n. 6, p. 589, doi. 10.1038/ng.3300

By:

Surakka, Ida;
Sarin, Antti-Pekka;
Kettunen, Johannes;
Hottenga, Jouke-Jan;
de Geus, Eco J;
Willemsen, Gonneke;
Boomsma, Dorret I;
Isaacs, Aaron;
van Duijn, Cornelia M;
Ladenvall, Claes;
Beekman, Marian;
Deelen, Joris;
Slagboom, P Eline;
Esko, Tõnu;
Ried, Janina S;
Nelson, Christopher P;
Samani, Nilesh J;
Willenborg, Christina;
Erdmann, Jeanette;
Blades, Matthew

Publication type:

Article

Systematic identification of trans eQTLs as putative drivers of known disease associations.

Published in:

Nature Genetics, 2013, v. 45, n. 10, p. 1238, doi. 10.1038/ng.2756

By:

Westra, Harm-Jan;
Peters, Marjolein J;
Esko, Tõnu;
Yaghootkar, Hanieh;
Schurmann, Claudia;
Kettunen, Johannes;
Christiansen, Mark W;
Fairfax, Benjamin P;
Schramm, Katharina;
Powell, Joseph E;
Zhernakova, Alexandra;
Zhernakova, Daria V;
Veldink, Jan H;
Van den Berg, Leonard H;
Karjalainen, Juha;
Withoff, Sebo;
Uitterlinden, André G;
Hofman, Albert;
Rivadeneira, Fernando;
't Hoen, Peter A C

Publication type:

Article

Genome-wide association study of periodontal pocketing in Finnish adults.

Published in:

BMC Oral Health, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12903-021-01964-8

By:

Tegelberg, Paula;
Leppilahti, Jussi Miikkael;
Ylöstalo, Atte;
Tervonen, Tellervo;
Kettunen, Johannes;
Suominen, Anna Liisa;
Ylöstalo, Pekka

Publication type:

Article

Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.

Published in:

2020

By:

Kettunen, Johannes;
Holmes, Michael V.;
Allara, Elias;
Anufrieva, Olga;
Ohukainen, Pauli;
Oliver-Williams, Clare;
Wang, Qin;
Tillin, Therese;
Hughes, Alun D.;
Kähönen, Mika;
Lehtimäki, Terho;
Viikari, Jorma;
Raitakari, Olli T.;
Salomaa, Veikko;
Järvelin, Marjo-Riitta;
Perola, Markus;
Smith, George Davey;
Chaturvedi, Nish;
Danesh, John;
Di Angelantonio, Emanuele

Publication type:

Correction Notice

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.

Published in:

PLoS Biology, 2019, v. 17, n. 12, p. N.PAG, doi. 10.1371/journal.pbio.3000572

By:

Kettunen, Johannes;
Holmes, Michael V.;
Allara, Elias;
Anufrieva, Olga;
Ohukainen, Pauli;
Oliver-Williams, Clare;
Wang, Qin;
Tillin, Therese;
Hughes, Alun D.;
Kähönen, Mika;
Lehtimäki, Terho;
Viikari, Jorma;
Raitakari, Olli T.;
Salomaa, Veikko;
Järvelin, Marjo-Riitta;
Perola, Markus;
Davey Smith, George;
Chaturvedi, Nish;
Danesh, John;
Di Angelantonio, Emanuele

Publication type:

Article

Clinical and biochemical associations of urinary metabolites: quantitative epidemiological approach on renal-cardiometabolic biomarkers.

Published in:

International Journal of Epidemiology, 2024, v. 53, n. 1, p. 1, doi. 10.1093/ije/dyad162

By:

Li, Tianqi;
Ihanus, Andrei;
Ohukainen, Pauli;
Järvelin, Marjo-Riitta;
Kähönen, Mika;
Kettunen, Johannes;
Raitakari, Olli T;
Lehtimäki, Terho;
Mäkinen, Ville-Petteri;
Tynkkynen, Tuulia;
Ala-Korpela, Mika

Publication type:

Article

There is always glucose in normal urine: unspecific excretion associated with serum glucose and glomerular filtration rate.

Published in:

International Journal of Epidemiology, 2022, v. 51, n. 6, p. 2022, doi. 10.1093/ije/dyac060

By:

Li, Tianqi;
Ihanus, Andrei;
Ohukainen, Pauli;
Järvelin, Marjo-Riitta;
Kettunen, Johannes;
Mäkinen, Ville-Petteri;
Tynkkynen, Tuulia;
Ala-Korpela, Mika

Publication type:

Article

Longitudinal profiling of metabolic ageing trends in two population cohorts of young adults.

Published in:

International Journal of Epidemiology, 2022, v. 51, n. 6, p. 1970, doi. 10.1093/ije/dyac062

By:

Mäkinen, Ville-Petteri;
Karsikas, Mari;
Kettunen, Johannes;
Lehtimäki, Terho;
Kähönen, Mika;
Viikari, Jorma;
Perola, Markus;
Salomaa, Veikko;
Järvelin, Marjo-Riitta;
Raitakari, Olli T;
Ala-Korpela, Mika

Publication type:

Article

EpiMetal: an open-source graphical web browser tool for easy statistical analyses in epidemiology and metabolomics.

Published in:

2020

By:

Ekholm, Jussi;
Ohukainen, Pauli;
Kangas, Antti J;
Kettunen, Johannes;
Wang, Qin;
Karsikas, Mari;
Khan, Anmar A;
Kingwell, Bronwyn A;
Kähönen, Mika;
Lehtimäki, Terho;
Raitakari, Olli T;
Järvelin, Marjo-Riitta;
Meikle, Peter J;
Ala-Korpela, Mika

Publication type:

journal article

Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics.

Published in:

2019

By:

Tynkkynen, Tuulia;
Wang, Qin;
Ekholm, Jussi;
Anufrieva, Olga;
Ohukainen, Pauli;
Vepsäläinen, Jouko;
Männikkö, Minna;
Keinänen-Kiukaanniemi, Sirkka;
Holmes, Michael V;
Goodwin, Matthew;
Ring, Susan;
Chambers, John C;
Kooner, Jaspal;
Järvelin, Marjo-Riitta;
Kettunen, Johannes;
Hill, Michael;
Smith, George Davey;
Ala-Korpela, Mika;
Davey Smith, George

Publication type:

journal article

Characterization of the metabolic profile associated with serum 25-hydroxyvitamin D: a cross-sectional analysis in population-based data.

Published in:

2016

By:

Vogt, Susanne;
Wahl, Simone;
Kettunen, Johannes;
Breitner, Susanne;
Kastenmüller, Gabi;
Gieger, Christian;
Suhre, Karsten;
Waldenberger, Melanie;
Kratzsch, Jürgen;
Perola, Markus;
Salomaa, Veikko;
Blankenberg, Stefan;
Zeller, Tanja;
Soininen, Pasi;
Kangas, Antti J.;
Peters, Annette;
Grallert, Harald;
Ala-Korpela, Mika;
Thorand, Barbara

Publication type:

journal article

Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates.

Published in:

International Journal of Epidemiology, 2015, v. 44, n. 2, p. 623, doi. 10.1093/ije/dyv093

By:

Qin Wang;
Kangas, Antti J.;
Soininen, Pasi;
Tiainen, Mika;
Tynkkynen, Tuulia;
Puukka, Katri;
Ruokonen, Aimo;
Viikari, Jorma;
Kähönen, Mika;
Lehtimäki, Terho;
Salomaa, Veikko;
Perola, Markus;
Smith, George Davey;
Raitakari, Olli T.;
Järvelin, Marjo-Riitta;
Würtz, Peter;
Kettunen, Johannes;
Ala-Korpela, Mika

Publication type:

Article

Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study.

Published in:

2011

By:

Kivimäki, Mika;
Magnussen, Costan G;
Juonala, Markus;
Kähönen, Mika;
Kettunen, Johannes;
Loo, Britt-Marie;
Lehtimäki, Terho;
Viikari, Jorma;
Raitakari, Olli T

Publication type:

journal article

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Published in:

Science Translational Medicine, 2016, v. 8, n. 323, p. 1, doi. 10.1126/scitranslmed.aad0015

By:

Laurila, Pirkka-Pekka;
Soronen, Jarkko;
Kooijman, Sander;
Forsström, Saara;
Boon, Mariëtte R.;
Surakka, Ida;
Kaiharju, Essi;
Coomans, Claudia P.;
Van Den Berg, Sjoerd A. A.;
Autio, Anu;
Sarin, Antti-Pekka;
Kettunen, Johannes;
Tikkanen, Emmi;
Manninen, Tuula;
Metso, Jari;
Silvennoinen, Reija;
Merikanto, Krista;
Ruuth, Maija;
Perttilä, Julia;
Mäkelä, Anne

Publication type:

Article

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression.

Published in:

Bioinformatics, 2014, v. 30, n. 14, p. 2026, doi. 10.1093/bioinformatics/btu140

By:

Marttinen, Pekka;
Pirinen, Matti;
Sarin, Antti-Pekka;
Gillberg, Jussi;
Kettunen, Johannes;
Surakka, Ida;
Kangas, Antti J.;
Soininen, Pasi;
O’Reilly, Paul;
Kaakinen, Marika;
Kähönen, Mika;
Lehtimäki, Terho;
Ala-Korpela, Mika;
Raitakari, Olli T.;
Salomaa, Veikko;
Järvelin, Marjo-Riitta;
Ripatti, Samuli;
Kaski, Samuel

Publication type:

Article

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts.

Published in:

Diabetologia, 2019, v. 62, n. 12, p. 2298, doi. 10.1007/s00125-019-05001-w

By:

Ahola-Olli, Ari V.;
Mustelin, Linda;
Kalimeri, Maria;
Kettunen, Johannes;
Jokelainen, Jari;
Auvinen, Juha;
Puukka, Katri;
Havulinna, Aki S.;
Lehtimäki, Terho;
Kähönen, Mika;
Juonala, Markus;
Keinänen-Kiukaanniemi, Sirkka;
Salomaa, Veikko;
Perola, Markus;
Järvelin, Marjo-Riitta;
Ala-Korpela, Mika;
Raitakari, Olli;
Würtz, Peter

Publication type:

Article

Insomnia does not mediate or modify the association between MTNR1B risk variant rs10830963 and glucose levels.

Published in:

2016

By:

Ollila, Hanna;
Kronholm, Erkki;
Kettunen, Johannes;
Silander, Kaisa;
Perola, Markus;
Porkka-Heiskanen, Tarja;
Salomaa, Veikko;
Paunio, Tiina

Publication type:

Letter

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

Published in:

Nature Communications, 2016, v. 7, n. 3, p. 11122, doi. 10.1038/ncomms11122

By:

Kettunen, Johannes;
Demirkan, Ayşe;
Würtz, Peter;
Draisma, Harmen H.M.;
Haller, Toomas;
Rawal, Rajesh;
Vaarhorst, Anika;
Kangas, Antti J.;
Lyytikäinen, Leo-Pekka;
Pirinen, Matti;
Pool, René;
Sarin, Antti-Pekka;
Soininen, Pasi;
Tukiainen, Taru;
Wang, Qin;
Tiainen, Mika;
Tynkkynen, Tuulia;
Amin, Najaf;
Zeller, Tanja;
Beekman, Marian

Publication type:

Article

A metabolic view on menopause and ageing.

Published in:

Nature Communications, 2014, v. 5, n. 8, p. 4708, doi. 10.1038/ncomms5708

By:

Auro, Kirsi;
Joensuu, Anni;
Fischer, Krista;
Kettunen, Johannes;
Salo, Perttu;
Mattsson, Hannele;
Niironen, Marjo;
Kaprio, Jaakko;
Eriksson, Johan G.;
Lehtimäki, Terho;
Raitakari, Olli;
Jula, Antti;
Tiitinen, Aila;
Jauhiainen, Matti;
Soininen, Pasi;
Kangas, Antti J.;
Kähönen, Mika;
Havulinna, Aki S.;
Ala-Korpela, Mika;
Salomaa, Veikko

Publication type:

Article

Insulin resistance and systemic metabolic changes in oral glucose tolerance test in 5340 individuals: an interventional study.

Published in:

2019

By:

Wang, Qin;
Jokelainen, Jari;
Auvinen, Juha;
Puukka, Katri;
Keinänen-Kiukaanniemi, Sirkka;
Järvelin, Marjo-Riitta;
Kettunen, Johannes;
Mäkinen, Ville-Petteri;
Ala-Korpela, Mika

Publication type:

journal article

HDL-Mediated Cholesterol Efflux Associates with Incident Kidney Disease.

Published in:

Clinical Chemistry, 2021, v. 67, n. 4, p. 689, doi. 10.1093/clinchem/hvab024

By:

Kuusisto, Sanna;
Kostara, Christina;
Kangas, Antti J.;
Perola, Markus;
Salomaa, Veikko;
Kettunen, Johannes;
Ala-Korpela, Mika

Publication type:

Article

Direct Estimation of HDL-Mediated Cholesterol Efflux Capacity from Serum.

Published in:

Clinical Chemistry, 2019, v. 65, n. 8, p. 1042, doi. 10.1373/clinchem.2018.299222

By:

Kuusisto, Sanna;
Holmes, Michael V.;
Ohukainen, Pauli;
Kangas, Antti J.;
Karsikas, Mari;
Tiainen, Mika;
Perola, Markus;
Salomaa, Veikko;
Kettunen, Johannes;
Ala-Korpela, Mika

Publication type:

Article

Genome-wide association study of sleep duration in the Finnish population.

Published in:

Journal of Sleep Research, 2014, v. 23, n. 6, p. 609, doi. 10.1111/jsr.12175

By:

Ollila, Hanna M.;
Kettunen, Johannes;
Pietiläinen, Olli;
Aho, Vilma;
Silander, Kaisa;
Kronholm, Erkki;
Perola, Markus;
Lahti, Jari;
Räikkönen, Katri;
Widen, Elisabeth;
Palotie, Aarno;
Eriksson, Johan G.;
Partonen, Timo;
Kaprio, Jaakko;
Salomaa, Veikko;
Raitakari, Olli;
Lehtimäki, Terho;
Sallinen, Mikael;
Härmä, Mikko;
Porkka‐Heiskanen, Tarja

Publication type:

Article

Genetic Determinants of Circulating Interleukin-1 Receptor Antagonist Levels and Their Association With Glycemic Traits.

Published in:

Diabetes, 2014, v. 63, n. 12, p. 4343, doi. 10.2337/db14-0731

By:

Herder, Christian;
Nuotio, Marja-Liisa;
Shah, Sonia;
Blankenberg, Stefan;
Brunner, Eric J.;
Carstensen, Maren;
Gieger, Christian;
Grallert, Harald;
Jula, Antti;
Kähönen, Mika;
Kettunen, Johannes;
Kivimäki, Mika;
Koenig, Wolfgang;
Kristiansson, Kati;
Langenberg, Claudia;
Lehtimäki, Terho;
Luotola, Kari;
Marzi, Carola;
Müller, Christian;
Peters, Annette

Publication type:

Article

Metabolic Signatures of Insulin Resistance in 7,098 Young Adults.

Published in:

Diabetes, 2012, v. 61, n. 6, p. 1372, doi. 10.2337/db11-1355

By:

Würtz, Peter;
Mäkinen, Ville-Petteri;
Soininen, Pasi;
Kangas, Antti J.;
Tukiainen, Taru;
Kettunen, Johannes;
Savolainen, Markku J.;
Tammelin, Tuija;
Viikari, Jorma S.;
Rönnemaa, Tapani;
Kahönen, Mika;
Lehtimäki, Terho;
Ripatti, Samuli;
Raitakari, Olli T.;
Järvelin, Marjo-Riitta;
Ala-Korpela, Mika

Publication type:

Article

A cross-omics integrative study of metabolic signatures of chronic obstructive pulmonary disease.

Published in:

2020

By:

Prokić, Ivana;
Lahousse, Lies;
de Vries, Maaike;
Liu, Jun;
Kalaoja, Marita;
Vonk, Judith M.;
van der Plaat, Diana A.;
van Diemen, Cleo C.;
van der Spek, Ashley;
Zhernakova, Alexandra;
Fu, Jingyuan;
Ghanbari, Mohsen;
Ala-Korpela, Mika;
Kettunen, Johannes;
Havulinna, Aki S.;
Perola, Markus;
Salomaa, Veikko;
Lind, Lars;
Ärnlöv, Johan;
Stricker, Bruno H. C.

Publication type:

journal article

Metabonomic, transcriptomic, and genomic variation of a population cohort.

Published in:

Molecular Systems Biology, 2010, v. 6, n. 1, p. 441, doi. 10.1038/msb.2010.93

By:

Inouye, Michael;
Kettunen, Johannes;
Soininen, Pasi;
Silander, Kaisa;
Ripatti, Samuli;
Kumpula, Linda S;
Hämäläinen, Eija;
Jousilahti, Pekka;
Kangas, Antti J;
Männistö, Satu;
Savolainen, Markku J;
Jula, Antti;
Leiviskä, Jaana;
Palotie, Aarno;
Salomaa, Veikko;
Perola, Markus;
Ala‐Korpela, Mika;
Peltonen, Leena

Publication type:

Article

Leveraging Northern European population history: novel low-frequency variants for polycystic ovary syndrome.

Published in:

2022

By:

Tyrmi, Jaakko S;
Arffman, Riikka K;
Pujol-Gualdo, Natàlia;
Kurra, Venla;
Morin-Papunen, Laure;
Sliz, Eeva;
Consortium, FinnGen;
Piltonen, Terhi T;
Laisk, Triin;
Kettunen, Johannes;
Laivuori, Hannele;
FinnGen Consortium, Estonian Biobank Research Team

Publication type:

journal article

An epigenome-wide association study of metabolic syndrome and its components.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77506-z

By:

Nuotio, Marja-Liisa;
Pervjakova, Natalia;
Joensuu, Anni;
Karhunen, Ville;
Hiekkalinna, Tero;
Milani, Lili;
Kettunen, Johannes;
Järvelin, Marjo-Riitta;
Jousilahti, Pekka;
Metspalu, Andres;
Salomaa, Veikko;
Kristiansson, Kati;
Perola, Markus

Publication type:

Article

Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140576

By:

Salo, Perttu P.;
Vaara, Satu;
Kettunen, Johannes;
Pirinen, Matti;
Sarin, Antti-Pekka;
Huikuri, Heikki;
Karhunen, Pekka J.;
Eskola, Markku;
Nikus, Kjell;
Lokki, Marja-Liisa;
Ripatti, Samuli;
Havulinna, Aki S.;
Salomaa, Veikko;
Palotie, Aarno;
Nieminen, Markku S.;
Sinisalo, Juha;
Perola, Markus

Publication type:

Article

Association of LIN28B with Adult Adiposity-Related Traits in Females.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0048785

By:

Leinonen, Jaakko T.;
Surakka, Ida;
Havulinna, Aki S.;
Kettunen, Johannes;
Luoto, Riitta;
Salomaa, Veikko;
Widén, Elisabeth

Publication type:

Article

Common Genetic Variants Associated with Sudden Cardiac Death: The FinSCDgen Study.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041675

By:

Lahtinen, Annukka M.;
Noseworthy, Peter A.;
Havulinna, Aki S.;
Jula, Antti;
Karhunen, Pekka J.;
Kettunen, Johannes;
Perola, Markus;
Kontula, Kimmo;
Newton-Cheh, Christopher;
Salomaa, Veikko

Publication type:

Article

A Genome-Wide Association Study Identifies UGT1A1 as a Regulator of Serum Cell-Free DNA in Young Adults: The Cardiovascular Risk in Young Finns Study.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035426

By:

Jylhävä, Juulia;
Lyytikäinen, Leo-Pekka;
Kähönen, Mika;
Hutri-Kähönen, Nina;
Kettunen, Johannes;
Viikari, Jorma;
Raitakari, Olli T.;
Lehtimäki, Terho;
Hurme, Mikko

Publication type:

Article

Genetic Profiling Using Genome-Wide Significant Coronary Artery Disease Risk Variants Does Not Improve the Prediction of Subclinical Atherosclerosis: The Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey - A Meta-Analysis of Three Independent Studies

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0028931

By:

Hernesniemi, Jussi A.;
Seppälä, Ilkka;
Lyytikäinen, Leo-Pekka;
Mononen, Nina;
Oksala, Niku;
Hutri-Kähönen, Nina;
Juonala, Markus;
Taittonen, Leena;
Smith, Erin N.;
Schork, Nicholas J.;
Wei Chen;
Srinivasan, Sathanur R.;
Berenson, Gerald S.;
Murray, Sarah S.;
Laitinen, Tomi;
Jula, Antti;
Kettunen, Johannes;
Ripatti, Samuli;
Laaksonen, Reijo;
Viikari, Jorma

Publication type:

Article

Genetic and observational evidence: No independent role for cholesterol efflux over static high‐density lipoprotein concentration measures in coronary heart disease risk assessment.

Published in:

Journal of Internal Medicine, 2022, v. 292, n. 1, p. 146, doi. 10.1111/joim.13479

By:

Kuusisto, Sanna;
Karjalainen, Minna K.;
Tillin, Therese;
Kangas, Antti J.;
Holmes, Michael V.;
Kähönen, Mika;
Lehtimäki, Terho;
Viikari, Jorma;
Perola, Markus;
Chaturvedi, Nishi;
Salomaa, Veikko;
Raitakari, Olli T.;
Järvelin, Marjo‐Riitta;
Kettunen, Johannes;
Ala‐Korpela, Mika

Publication type:

Article

Association between mitochondrial DNA haplogroups J and K, serum branched-chain amino acids and lowered capability for endurance exercise.

Published in:

BMC Sports Science, Medicine & Rehabilitation, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13102-022-00485-3

By:

Kiiskilä, Jukka M.;
Hassinen, Ilmo E.;
Kettunen, Johannes;
Kytövuori, Laura;
Mikkola, Ilona;
Härkönen, Pirjo;
Jokelainen, Jari J.;
Keinänen-Kiukaanniemi, Sirkka;
Perola, Markus;
Majamaa, Kari

Publication type:

Article