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Clonality: more than just a tumor-progression model.
Published in:
1993
By:
- Kern, Scott E.;
- Kern, S E
Publication type:
commentary
Use and Benefits of a Web Site for Pancreatic Cancer.
Published in:
JAMA: Journal of the American Medical Association, 1998, v. 280, n. 15, p. 1309, doi. 10.1001/jama.280.15.1309-a
By:
- Goggins, Michael;
- Lietman, Amanda;
- Miller, Robert E.;
- Yeo, Charles J.;
- Jaffee, Elizabeth;
- Coleman, JoAnn;
- O’Reilly, Seamus;
- Cullen, Bernadette;
- Cameron, John L.;
- Kern, Scott E.;
- Hruban, Ralph H.
Publication type:
Article
Pancreatic cancer pathology viewed in the light of evolution.
Published in:
Cancer & Metastasis Reviews, 2021, v. 40, n. 3, p. 661, doi. 10.1007/s10555-020-09953-z
By:
- Noë, Michaël;
- Hong, Seung-Mo;
- Wood, Laura D.;
- Thompson, Elizabeth D.;
- Roberts, Nicholas J.;
- Goggins, Michael G.;
- Klein, Alison P.;
- Eshleman, James R.;
- Kern, Scott E.;
- Hruban, Ralph H.
Publication type:
Article
Allelic Loss in Colorectal Carcinoma.
Published in:
JAMA: Journal of the American Medical Association, 1989, v. 261, n. 21, p. 3099, doi. 10.1001/jama.1989.03420210047014
By:
- Kern, Scott E.;
- Fearon, Eric R.;
- Tersmette, Kasper W.F.;
- Enterline, John P.;
- Leppert, Mark;
- Nakamura, Yusuke;
- White, Ray;
- Vogelstein, Bert;
- Hamilton, Stanley R.
Publication type:
Article
The complexity of pancreatic ductal cancers and multidimensional strategies for therapeutic targeting.
Published in:
Journal of Pathology, 2011, v. 223, n. 2, p. 296, doi. 10.1002/path.2813
By:
- Kern, Scott E;
- Shi, Chanjuan;
- Hruban, Ralph H
Publication type:
Article
Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion.
Published in:
Modern Pathology, 2005, v. 18, n. 7, p. 959, doi. 10.1038/modpathol.3800377
By:
- Hustinx, Steven R.;
- Leoni, Lorenzo M.;
- Yeo, Charles J.;
- Brown, Priscilla N.;
- Goggins, Michael;
- Kern, Scott E.;
- Hruban, Ralph H.;
- Maitra, Anirban
Publication type:
Article
Role of the DPC4 Tumor Suppressor Gene in Adenocarcinoma of the Ampulla of Vater: Analysis of 140 Cases.
Published in:
Modern Pathology, 2003, v. 16, n. 3, p. 272, doi. 10.1097/01.MP.0000057246.03448.26
By:
- McCarthy, Denis M.;
- Hruban, Ralph H.;
- Argani, Pedram;
- Howe, James R.;
- Conlon, Kevin C.;
- Brennan, Murray F.;
- Zahurak, Marianna;
- Wilentz, Robb E.;
- Cameron, John L.;
- Yeo, Charles J.;
- Kern, Scott E.;
- Klimstra, David S.
Publication type:
Article
Analysis of Polymorphisms and Haplotype Structure of the Human Thymidylate Synthase Genetic Region: A Tool for Pharmacogenetic Studies.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034426
By:
- Ghosh, Soma;
- Zulfiquer Hossain, M.;
- Borges, Michael;
- Goggins, Michael G.;
- Ingersoll, Roxann G.;
- Eshleman, James R.;
- Klein, Alison P.;
- Kern, Scott E.
Publication type:
Article
Improved DNA Electrophoresis in Conditions Favoring Polyborates and Lewis Acid Complexation.
Published in:
PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0011318
By:
- Singhal, Hari;
- Ren, Yunzhao R.;
- Kern, Scott E.
Publication type:
Article
Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer.
Published in:
Oncogene, 2005, v. 24, n. 22, p. 3652, doi. 10.1038/sj.onc.1208411
By:
- Martin, Sean T.;
- Matsubayashi, Hiroyuki;
- Rogers, Carmelle D.;
- Philips, Juliet;
- Couch, Fergus J.;
- Brune, Kieran;
- Yeo, Charles J.;
- Kern, Scott E.;
- Hruban, Ralph H.;
- Goggins, Michael
Publication type:
Article
Molecular genetic alterations as potential prognostic indicators in colorectal carcinoma and molecular genetics of colorectal carcinoma.
Published in:
1993
By:
- Hamilton, Stanley R.;
- Kern, Scott E.;
- Hamilton, S R;
- Kern, S E
Publication type:
Letter
LOCAL IgA-MEMORY RESPONSE TO BACTERIAL ANTIGENS*.
Published in:
Annals of the New York Academy of Sciences, 1983, v. 409, n. 1, p. 734, doi. 10.1111/j.1749-6632.1983.tb26912.x
By:
- Keren, David F.;
- Scott, Patricia J.;
- McDonald, Roderick A.;
- Kern, Scott E.
Publication type:
Article
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
Published in:
Nature, 2011, v. 475, n. 7354, p. 106, doi. 10.1038/nature10189
By:
- DeNicola, Gina M.;
- Karreth, Florian A.;
- Humpton, Timothy J.;
- Gopinathan, Aarthi;
- Cong Wei;
- Frese, Kristopher;
- Mangal, Dipti;
- Yu, Kenneth H.;
- Yeo, Charles J.;
- Calhoun, Eric S.;
- Scrimieri, Francesca;
- Winter, Jordan M.;
- Hruban, Ralph H.;
- Iacobuzio-Donahue, Christine;
- Kern, Scott E.;
- Blair, Ian A.;
- Tuveson, David A.
Publication type:
Article
High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter.
Published in:
Carcinogenesis, 2002, v. 23, n. 6, p. 949, doi. 10.1093/carcin/23.6.949
By:
- Sohn, Taylor A.;
- Bansal, Ravi;
- Su, Gloria H.;
- Murphy, Kathleen M.;
- Kern, Scott E.
Publication type:
Article
Functional mapping of the MH1 DNA-binding domain of DPC4/SMAD4.
Published in:
Nucleic Acids Research, 2000, v. 28, n. 12, p. 2363, doi. 10.1093/nar/28.12.2363
By:
- Jones, Jessa B.;
- Kern, Scott E.
Publication type:
Article
Differing rates of loss of DPC4 expression and of p53 overexpression among carcinomas of the proximal and distal bile ducts.
Published in:
Cancer (0008543X), 2001, v. 91, n. 7, p. 1332, doi. 10.1002/1097-0142(20010401)91:7<1332::AID-CNCR1136>3.0.CO;2-4
By:
- Argani, Pedram;
- Shaukat, Aasma;
- Kaushal, Manju;
- Wilentz, Robb E.;
- Su, Gloria H.;
- Sohn, Taylor A.;
- Yeo, Charles J.;
- Cameron, John L.;
- Kern, Scott E.;
- Hruban, Ralph H.
Publication type:
Article
Does tumorigenesis select for or against mutations of the DNA repair-associated genes BRCA2 and MRE11?: Considerations from somatic mutations in microsatellite unstable (MSI) gastrointestinal cancers.
Published in:
BMC Genetics, 2006, v. 7, p. 1
By:
- S^van^der^Heijden, Michiel;
- Brody, Jonathan R;
- Elghalbzouri- Maghrani, Elhaam;
- Zdzienicka, Malgorzata Z;
- Kern, Scott E
Publication type:
Article
Novel genotoxicity assays identify norethindrone to activate p53 and phosphorylate H2AX.
Published in:
Carcinogenesis, 2005, v. 26, n. 10, p. 1811
By:
- Saeed R. Kahn;
- Scott E. Kern
Publication type:
Article
Transforming growth factor-β responsiveness in DPC4/SMAD4-null cancer cells.
Published in:
Molecular Carcinogenesis, 1999, v. 26, n. 1, p. 37, doi. 10.1002/(SICI)1098-2744(199909)26:1<37::AID-MC5>3.0.CO;2-6
By:
- Dai, Jia Le;
- Schutte, Mieke;
- Bansal, Ravi K.;
- Wilentz, Robb E.;
- Sugar, Avrahom Y.;
- Kern, Scott E.
Publication type:
Article
SOS1 mutations are rare in human malignancies: Implications for Noonan syndrome patients.
Published in:
Genes, Chromosomes & Cancer, 2008, v. 47, n. 3, p. 253, doi. 10.1002/gcc.20527
By:
- Swanson, Kenneth D.;
- Winter, Jordan M.;
- Reis, Marcelo;
- Bentires-Alj, Mohamed;
- Greulich, Heidi;
- Grewal, Rupinder;
- Hruban, Ralph H.;
- Yeo, Charles J.;
- Yassin, Yosuf;
- Iartchouk, Oleg;
- Montgomery, Kate;
- Whitman, Susan P.;
- Caligiuri, Michael A.;
- Loh, Mignon L.;
- Gilliland, D. Gary;
- Look, A. Thomas;
- Kucherlapati, Raju;
- Kern, Scott E.;
- Meyerson, Matthew;
- Neel, Benjamin G.
Publication type:
Article
Copy‐number methods dramatically underestimate loss of heterozygosity in cancer.
Published in:
Genes, Chromosomes & Cancer, 2006, v. 45, n. 11, p. 1070, doi. 10.1002/gcc.20365
By:
- Eric S. Calhoun;
- Eike Gallmeier;
- Steven C. Cunningham;
- James R. Eshleman;
- Ralph H. Hruban;
- Scott E. Kern
Publication type:
Article
Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers.
Published in:
Genes, Chromosomes & Cancer, 2000, v. 27, n. 4, p. 353, doi. 10.1002/(SICI)1098-2264(200004)27:4<353::AID-GCC3>3.0.CO;2-5
By:
- Hilgers, Werner;
- Song, Jason J.;
- Haye, Marianne;
- Hruban, Ralph R.;
- Kern, Scott E.;
- Fearon, Eric R.
Publication type:
Article
Genomic FHIT analysis in RER+ and RER− adenocarcinomas of the pancreas.
Published in:
Genes, Chromosomes & Cancer, 2000, v. 27, n. 3, p. 239, doi. 10.1002/(SICI)1098-2264(200003)27:3<239::AID-GCC3>3.0.CO;2-X
By:
- Hilgers, Werner;
- Koerkamp, Bas Groot;
- Geradts, Joseph;
- Tang, David J.;
- Yeo, Charles J.;
- Hruban, Ralph H.;
- Kern, Scott E.
Publication type:
Article
Genomic alterations in distal bile duct carcinoma by comparative genomic hybridization and karyotype analysis.
Published in:
Genes, Chromosomes & Cancer, 1999, v. 26, n. 3, p. 185, doi. 10.1002/(SICI)1098-2264(199911)26:3<185::AID-GCC1>3.0.CO;2-9
By:
- Rijken, Arjen M.;
- Hu, Jie;
- Perlman, Elizabeth J.;
- Morsberger, Laura A.;
- Long, Patricia;
- Kern, Scott E.;
- Hruban, Ralph H.;
- Yeo, Charles J.;
- Griffin, Constance A.
Publication type:
Article
Molecular genetic basis of pancreatic adenocarcinoma.
Published in:
Genes, Chromosomes & Cancer, 1999, v. 26, n. 1, p. 1, doi. 10.1002/(SICI)1098-2264(199909)26:1<1::AID-GCC1>3.0.CO;2-X
By:
- Hilgers, Werner;
- Kern, Scott E.
Publication type:
Article
Novel homozygous deletions of chromosomal band 18q22 in pancreatic adenocarcinoma identified by STS marker scanning.
Published in:
Genes, Chromosomes & Cancer, 1999, v. 25, n. 4, p. 370, doi. 10.1002/(SICI)1098-2264(199908)25:4<370::AID-GCC9>3.0.CO;2-S
By:
- Hilgers, Werner;
- Su, Gloria H.;
- Koerkamp, Bas Groot;
- Tang, David J.;
- Shekher, Manu C.;
- Sugar, Avrahom Y.;
- Yeo, Charles J.;
- Hruban, Ralph H.;
- Kern, Scott E.
Publication type:
Article
High-resolution deletion mapping of chromosome arm 1p in pancreatic cancer identifies a major consensus region at 1p35.
Published in:
Genes, Chromosomes & Cancer, 1999, v. 24, n. 4, p. 351, doi. 10.1002/(SICI)1098-2264(199904)24:4<351::AID-GCC9>3.0.CO;2-Y
By:
- Hilgers, Werner;
- Tang, David J.;
- Sugar, Avrahom Y.;
- Shekher, Manu C.;
- Hruban, Ralph H.;
- Kern, Scott E.
Publication type:
Article
Genome Annotation by Shotgun Inactivation of a Native Gene in Hemizygous Cells: Application to BRCA2 with Implication of Hypomorphic Variants.
Published in:
Human Mutation, 2015, v. 36, n. 2, p. 260, doi. 10.1002/humu.22736
By:
- Ghosh, Soma;
- Bhunia, Anil K.;
- Paun, Bogdan C.;
- Gilbert, Samuel F.;
- Dhru, Urmil;
- Patel, Kalpesh;
- Kern, Scott E.
Publication type:
Article
Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers.
Published in:
Human Mutation, 2006, v. 27, n. 10, p. 1060, doi. 10.1002/humu.9452
By:
- Wood, Laura D.;
- Calhoun, Eric S.;
- Silliman, Natalie;
- Ptak, Janine;
- Szabo, Steve;
- Powell, Steve M.;
- Riggins, Gregory J.;
- Wang, Tian-Li;
- Yan, Hai;
- Gazdar, Adi;
- Kern, Scott E.;
- Pennacchio, Len;
- Kinzler, Kenneth W.;
- Vogelstein, Bert;
- Velculescu, Victor E.
Publication type:
Article
Erratum: A double missense variation of the BUB1 gene and a defective mitotic spindle checkpoint in the pancreatic cancer cell line Hs766T.
Published in:
Human Mutation, 2005, v. 26, n. 6, p. 592, doi. 10.1002/humu.9387
By:
- Hempen, Paula M.;
- Kurpad, Harsha;
- Calhoun, Eric S.;
- Abraham, Susan;
- Kern, Scott E.
Publication type:
Article
A double missense variation of the BUB1 gene and a defective mitotic spindle checkpoint in the pancreatic cancer cell line Hs766TCommunicated by Mark H. PaalmanOnline Citation: Human Mutation, Mutation in Brief #591 (2002) Onlinehttp://www.interscience.wiley.com/humanmutation/pdf/mutation/591.pdf
Published in:
Human Mutation, 2003, v. 21, n. 4, p. 445, doi. 10.1002/humu.9120
By:
- Paula M. Hempen;
- Harsha Kurpad;
- Eric S. Calhoun;
- Susan Abraham;
- Scott E. Kern
Publication type:
Article
Mutation rate of MAP2K4/MKK4 in breast carcinoma.
Published in:
Human Mutation, 2002, v. 19, n. 1, p. 81, doi. 10.1002/humu.9002
By:
- Su, Gloria H.;
- Song, Jason J.;
- Repasky, Elizabeth A.;
- Schutte, Mieke;
- Kern, Scott E.
Publication type:
Article
Oncogenic levels of mitogen-activated protein kinase (MAPK) signaling of the dinucleotide KRAS2 mutations G12F and GG12-13VC.
Published in:
Human Mutation, 2001, v. 18, n. 4, p. 357, doi. 10.1002/humu.1202
By:
- Feldser, David M.;
- Kern, Scott E.
Publication type:
Article
Novel germline p16INK4 allele (Asp145Cys) in a family with multiple pancreatic carcinomas.
Published in:
Human Mutation, 1998, v. 12, n. 1, p. 70, doi. 10.1002/(SICI)1098-1004(1998)12:1<70::AID-HUMU12>3.0.CO;2-J
By:
- Moskaluk, Christopher A.;
- Hruban, Ralph H.;
- Lietman, Amanda;
- Smyrk, Tom;
- Fusaro, Lavonne;
- Fusaro, Ramon;
- Lynch, Jane;
- Yeo, Charles J.;
- Jackson, Charles E.;
- Lynch, Henry T.;
- Kern, Scott E.
Publication type:
Article
Radiolabeled Anti--Claudin 4 and Anti--Prostate Stem Cell Antigen: Initial Imaging in Experimental Models of Pancreatic Cancer.
Published in:
Molecular Imaging, 2007, v. 6, n. 2, p. 131, doi. 10.2310/7290.2007.00010
By:
- Foss, Catherine A.;
- Fox, James J.;
- Feldmann, Georg;
- Maitra, Anirban;
- Iacobuzio-Donohue, Christine;
- Kern, Scott E.;
- Hruban, Ralph;
- Pomper, Martin G.
Publication type:
Article
Microvascular Architecture in a Case of Gastric Antral Vascular Ectasia (Watermelon Stomach).
Published in:
American Journal of Gastroenterology (Springer Nature), 2014, v. 109, n. 3, p. 449, doi. 10.1038/ajg.2013.449
By:
- Kern, Scott E;
- Sitzmann, James V
Publication type:
Article

Found: 36

Clonality: more than just a tumor-progression model.

Use and Benefits of a Web Site for Pancreatic Cancer.

Pancreatic cancer pathology viewed in the light of evolution.

Allelic Loss in Colorectal Carcinoma.

The complexity of pancreatic ductal cancers and multidimensional strategies for therapeutic targeting.

Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion.

Role of the DPC4 Tumor Suppressor Gene in Adenocarcinoma of the Ampulla of Vater: Analysis of 140 Cases.

Analysis of Polymorphisms and Haplotype Structure of the Human Thymidylate Synthase Genetic Region: A Tool for Pharmacogenetic Studies.

Improved DNA Electrophoresis in Conditions Favoring Polyborates and Lewis Acid Complexation.

Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer.

Molecular genetic alterations as potential prognostic indicators in colorectal carcinoma and molecular genetics of colorectal carcinoma.

LOCAL IgA-MEMORY RESPONSE TO BACTERIAL ANTIGENS*.

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.

High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter.

Functional mapping of the MH1 DNA-binding domain of DPC4/SMAD4.

Differing rates of loss of DPC4 expression and of p53 overexpression among carcinomas of the proximal and distal bile ducts.

Does tumorigenesis select for or against mutations of the DNA repair-associated genes BRCA2 and MRE11?: Considerations from somatic mutations in microsatellite unstable (MSI) gastrointestinal cancers.

Novel genotoxicity assays identify norethindrone to activate p53 and phosphorylate H2AX.

Transforming growth factor-β responsiveness in DPC4/SMAD4-null cancer cells.

SOS1 mutations are rare in human malignancies: Implications for Noonan syndrome patients.

Copy‐number methods dramatically underestimate loss of heterozygosity in cancer.

Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers.

Genomic FHIT analysis in RER<sup>+</sup> and RER<sup>−</sup> adenocarcinomas of the pancreas.

Genomic alterations in distal bile duct carcinoma by comparative genomic hybridization and karyotype analysis.

Molecular genetic basis of pancreatic adenocarcinoma.

Novel homozygous deletions of chromosomal band 18q22 in pancreatic adenocarcinoma identified by STS marker scanning.

High-resolution deletion mapping of chromosome arm 1p in pancreatic cancer identifies a major consensus region at 1p35.

Genome Annotation by Shotgun Inactivation of a Native Gene in Hemizygous Cells: Application to BRCA2 with Implication of Hypomorphic Variants.

Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers.

Erratum: A double missense variation of the BUB1 gene and a defective mitotic spindle checkpoint in the pancreatic cancer cell line Hs766T.

A double missense variation of the BUB1 gene and a defective mitotic spindle checkpoint in the pancreatic cancer cell line Hs766TCommunicated by Mark H. PaalmanOnline Citation: Human Mutation, Mutation in Brief #591 (2002) Onlinehttp://www.interscience.wiley.com/humanmutation/pdf/mutation/591.pdf

Mutation rate of MAP2K4/MKK4 in breast carcinoma.

Oncogenic levels of mitogen-activated protein kinase (MAPK) signaling of the dinucleotide KRAS2 mutations G12F and GG12-13VC.

Novel germline p16<sup>INK4</sup> allele (Asp145Cys) in a family with multiple pancreatic carcinomas.

Radiolabeled Anti--Claudin 4 and Anti--Prostate Stem Cell Antigen: Initial Imaging in Experimental Models of Pancreatic Cancer.

Microvascular Architecture in a Case of Gastric Antral Vascular Ectasia (Watermelon Stomach).