Works by Kern, Philip A.

Results: 86

The Immune System in Obesity: Developing Paradigms Amidst Inconvenient Truths.

Published in:

2017

By:

Agrawal, Madhur;
Kern, Philip;
Nikolajczyk, Barbara;
Kern, Philip A;
Nikolajczyk, Barbara S

Publication type:

journal article

Two Cases of Surreptitious Steroid Use Uncovered Utilizing Urine Synthetic Glucocorticoid Testing.

Published in:

JCEM Case Reports, 2023, v. 1, n. 6, p. 1, doi. 10.1210/jcemcr/luad132

By:

Pape, Bryn J;
Kern, Philip A

Publication type:

Article

Bilirubin Levels Are Negatively Correlated with Adiposity in Obese Men and Women, and Its Catabolized Product, Urobilin, Is Positively Associated with Insulin Resistance.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 170, doi. 10.3390/antiox12010170

By:

Kipp, Zachary A.;
Xu, Mei;
Bates, Evelyn A.;
Lee, Wang-Hsin;
Kern, Philip A.;
Hinds Jr., Terry D.

Publication type:

Article

Stratification by obesity class, rather than age, can identify a higher percent of children at risk for non‐alcoholic fatty liver disease and metabolic dysfunction.

Published in:

Pediatric Obesity, 2022, v. 17, n. 3, p. 1, doi. 10.1111/ijpo.12862

By:

Radulescu, Aurelia;
Dugan, Adam J.;
Killian, Mary;
Attia, Suzanna L.;
Mouzaki, Marialena;
Fuchs, George J.;
Kohli, Rohit;
Bada, Henrietta;
Kern, Philip A.;
Softic, Samir

Publication type:

Article

Social Network Analysis to Assess the Impact of the CTSA on Biomedical Research Grant Collaboration.

Published in:

CTS: Clinical & Translational Science, 2015, v. 8, n. 2, p. 150, doi. 10.1111/cts.12247

By:

Nagarajan, Radhakrishnan;
Peterson, Charlotte A.;
Lowe, Jane S.;
Wyatt, Stephen W.;
Tracy, Timothy S.;
Kern, Philip A.

Publication type:

Article

Feasibility of implementing time‐restricted eating in women with mild cognitive impairment.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.089509

By:

Thomas, Matthew;
Jicha, Gregory A;
Harp, Jordan P.;
Kern, Philip A;
Sears, Dorothy D;
James, Dara L;
Katsumata, Yuriko;
Pendergast, Julie S

Publication type:

Article

A muscle cell‐macrophage axis involving matrix metalloproteinase 14 facilitates extracellular matrix remodeling with mechanical loading.

Published in:

FASEB Journal, 2022, v. 36, n. 2, p. 1, doi. 10.1096/fj.202100182RR

By:

Peck, Bailey D.;
Murach, Kevin A.;
Walton, R. Grace;
Simmons, Alexander J.;
Long, Douglas E.;
Kosmac, Kate;
Dungan, Cory M.;
Kern, Philip A.;
Bamman, Marcas M.;
Peterson, Charlotte A.

Publication type:

Article

Potential Benefits of Combined Statin and Metformin Therapy on Resistance Training Response in Older Individuals.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.872745

By:

Long, Douglas E.;
Kosmac, Kate;
Dungan, Cory M.;
Bamman, Marcas M.;
Peterson, Charlotte A.;
Kern, Philip A.

Publication type:

Article

Targeting IκB kinase β in Adipocyte Lineage Cells for Treatment of Obesity and Metabolic Dysfunctions.

Published in:

Stem Cells, 2016, v. 34, n. 7, p. 1883, doi. 10.1002/stem.2358

By:

Helsley, Robert N.;
Sui, Yipeng;
Park, Se-Hyung;
Liu, Zun;
Lee, Richard G.;
Zhu, Beibei;
Kern, Philip A.;
Zhou, Changcheng

Publication type:

Article

Inclusion of adrenal crisis in the differential diagnosis of distributive shock.

Published in:

American Journal of Health-System Pharmacy, 2020, v. 77, n. 6, p. 415, doi. 10.1093/ajhp/zxz324

By:

Tompkins, Madeline G;
Bissell, Brittany D;
Sowders, Virginia;
Kern, Philip A

Publication type:

Article

The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans.

Published in:

2020

By:

Finlin, Brian S.;
Memetimin, Hasiyet;
Beibei Zhu;
Confides, Amy L.;
Vekaria, Hemendra J.;
El Khouli, Riham H.;
Johnson, Zachary R.;
Westgate, Philip M.;
Jianzhong Chen;
Morris, Andrew J.;
Sullivan, Patrick G.;
Dupont-Versteegden, Esther E.;
Kern, Philip A.;
Zhu, Beibei;
Chen, Jianzhong

Publication type:

journal article

Severe Hypercalcemia From Inhalation Pneumonitis via Activation of 1,25 Dihydroxyvitamin D.

Published in:

Journal of the Endocrine Society, 2022, v. 6, n. 6, p. 1, doi. 10.1210/jendso/bvac066

By:

Rosenstein, Kyle;
Kern, Philip A

Publication type:

Article

Adrenal Vein Cortisol to Metanephrine Ratio for Localizing ACTH-Independent Cortisol-Producing Adenoma: A Case Report.

Published in:

2021

By:

Raj, Rishi;
Kern, Philip A;
Ghanta, Neelima;
Uy, Edilfavia M;
Asadipooya, Kamyar

Publication type:

Case Study

Effect of Rifaximin Treatment on Endotoxemia and Insulin Sensitivity in Humans.

Published in:

Journal of the Endocrine Society, 2019, v. 3, n. 9, p. 1641, doi. 10.1210/js.2019-00148

By:

Finlin, Brian S;
Zhu, Beibei;
Boyechko, Tania;
Westgate, Philip M;
Chia, Chee W;
Egan, Josephine M;
Kern, Philip A

Publication type:

Article

T cells dominate peripheral inflammation in a cross-sectional analysis of obesity-associated diabetes.

Published in:

2022

By:

Pugh, Gabriella H.;
Fouladvand, Sajjad;
SantaCruz‐Calvo, Sara;
Agrawal, Madhur;
Zhang, Xiaohua Douglas;
Chen, Jin;
Kern, Philip A.;
Nikolajczyk, Barbara S.;
SantaCruz-Calvo, Sara

Publication type:

journal article

Aldose reductase promotes diet-induced obesity via induction of senescence in subcutaneous adipose tissue.

Published in:

2022

By:

Thiagarajan, Devi;
Quadri, Nosirudeen;
Jawahar, Shabnam;
Zirpoli, Hylde;
del Pozo, Carmen Hurtado;
López‐Díez, Raquel;
Hasan, Syed Nurul;
Yepuri, Gautham;
Gugger, Paul F.;
Finlin, Brian S.;
Kern, Philip A.;
Gabbay, Kenneth;
Schmidt, Ann Marie;
Ramasamy, Ravichandran;
López-Díez, Raquel

Publication type:

journal article

Improved β-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-26995-1

By:

Memetimin, Hasiyet;
Zhu, Beibei;
Lee, Sangderk;
Katz, Wendy S.;
Kern, Philip A.;
Finlin, Brian S.

Publication type:

Article

Human Body Composition and Immunity: Visceral Adipose Tissue Produces IL-15 and Muscle Strength Inversely Correlates with NK Cell Function in Elderly Humans.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00440

By:

Al-Attar, Ahmad;
Presnell, Steven R.;
Clasey, Jody L.;
Long, Douglas E.;
Walton, R. Grace;
Sexton, Morgan;
Starr, Marlene E.;
Kern, Philip A.;
Peterson, Charlotte A.;
Lutz, Charles T.

Publication type:

Article

Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms.

Published in:

Frontiers in Aging, 2022, p. 1, doi. 10.3389/fragi.2022.924003

By:

Conway, Rachel;
Rockhold, Jack Donato;
SantaCruz-Calvo, Sara;
Zukowski, Emelia;
Pugh, Gabriella H.;
Hasturk, Hatice;
Kern, Philip A.;
Nikolajczyk, Barbara S.;
Bharath, Leena P.

Publication type:

Article

Ectopic fat accumulation and metabolic syndrome.

Published in:

Diabetes, Obesity & Metabolism, 2007, v. 9, n. 1, p. 1, doi. 10.1111/j.1463-1326.2006.00590.x

By:

Rasouli, Neda;
Molavi, Behzad;
Elbein, Steven C.;
Kern, Philip A.

Publication type:

Article

Metformin to Augment Strength Training Effective Response in Seniors (MASTERS): study protocol for a randomized controlled trial.

Published in:

2017

By:

Long, Doug E.;
Peck, Bailey D.;
Martz, Jenny L.;
Tuggle, S. Craig;
Bush, Heather M.;
McGwin, Gerald;
Kern, Philip A.;
Bamman, Marcas M.;
Peterson, Charlotte A.

Publication type:

journal article

Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone.

Published in:

2007

By:

Yao-Borengasser, Aiwei;
Varma, Vijayalakshmi;
Bodles, Angela M;
Rasouli, Neda;
Phanavanh, Bounleut;
Lee, Mi-Jeong;
Starks, Tasha;
Kern, Leslie M;
Spencer, Horace J 3rd;
Rashidi, Amir Adel;
McGehee, Robert E Jr;
Fried, Susan K;
Kern, Philip A

Publication type:

journal article

Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation.

Published in:

2007

By:

Varma, Vijayalakshmi;
Yao-Borengasser, Aiwei;
Rasouli, Neda;
Bodles, Angela M.;
Phanavanh, Bounleut;
Mi-Jeong Lee;
Starks, Tasha;
Kern, Leslie M.;
Spencer, Horace J. III;
McGehee, Robert E.;
Fried, Susan K.;
Kern, Philip A.

Publication type:

journal article

Effect of Weight Loss on Muscle Fiber Type, Fiber Size, Capillarity, and Succinate Dehydrogenase Activity in Humans.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 11, p. 4185, doi. 10.1210/jcem.84.11.6090

By:

KERN, PHILIP A.;
SIMSOLO, ROSA B.;
FOURNIER, MARIO

Publication type:

Article

142 A Community Mini-Grant Program: Community Leaders and Academic Partners Work Together to Improve Health in Appalachian Kentucky.

Published in:

2022

By:

Hall, Ashley G.;
Kern, Philip A.;
Mudd-Martin

Publication type:

Abstract

A tribute to James E. "Jim" Heubi, MD.

Published in:

Journal of Clinical & Translational Science, 2022, v. 6, n. 1, p. 1, doi. 10.1017/cts.2022.21

By:

Kern, Philip A.

Publication type:

Article

KL2 scholars' perceptions of factors contributing to sustained translational science career success.

Published in:

Journal of Clinical & Translational Science, 2022, v. 6, n. 1, p. 1, doi. 10.1017/cts.2021.886

By:

Smyth, Susan S.;
Coller, Barry S.;
Jackson, Rebecca D.;
Kern, Philip A.;
McIntosh, Scott;
Meagher, Emma A.;
Rubio, Doris M.;
Sandberg, Kathryn;
Tsevat, Joel;
Umans, Jason G.;
Attia, Jacqueline;
Baker, Heather L.;
Nagel, Joan D.;
McMullen, Colleen A.;
Rosemond, Erica

Publication type:

Article

Adipose Tissue Mast Cells Promote Human Adipose Beiging in Response to Cold.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45136-9

By:

Finlin, Brian S.;
Confides, Amy L.;
Zhu, Beibei;
Boulanger, Mary C.;
Memetimin, Hasiyet;
Taylor, Kyle W.;
Johnson, Zachary R.;
Westgate, Philip M.;
Dupont-Versteegden, Esther E.;
Kern, Philip A.

Publication type:

Article

Adipose Tissue Hypoxia, Inflammation, and Fibrosis in Obese Insulin-Sensitive and Obese Insulin-Resistant Subjects.

Published in:

2016

By:

Lawler, Helen M;
Underkofler, Chantal M;
Kern, Philip A;
Erickson, Christopher;
Bredbeck, Brooke;
Rasouli, Neda

Publication type:

journal article

Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance.

Published in:

2011

By:

Spencer, Michael;
Unal, Resat;
Zhu, Beibei;
Rasouli, Neda;
McGehee, Robert E Jr;
Peterson, Charlotte A;
Kern, Philip A

Publication type:

journal article

Insulin resistance in African-American and Caucasian women: differences in lipotoxicity, adipokines, and gene expression in adipose tissue and muscle.

Published in:

2010

By:

Smith, Latasha M;
Yao-Borengasser, Aiwei;
Starks, Tasha;
Tripputi, Mark;
Kern, Philip A;
Rasouli, Neda

Publication type:

journal article

Matrix metalloproteinase-9 is increased in obese subjects and decreases in response to pioglitazone.

Published in:

2010

By:

Unal, Resat;
Yao-Borengasser, Aiwei;
Varma, Vijayalakshmi;
Rasouli, Neda;
Labbate, Craig;
Kern, Philip A;
Ranganathan, Gouri

Publication type:

journal article

The impact of exercise training compared to caloric restriction on hepatic and peripheral insulin resistance in obesity.

Published in:

2009

By:

Coker, Robert H;
Williams, Rick H;
Yeo, Sophie E;
Kortebein, Patrick M;
Bodenner, Don L;
Kern, Philip A;
Evans, William J

Publication type:

journal article

Adipocytokines and the metabolic complications of obesity.

Published in:

2008

By:

Rasouli, Neda;
Kern, Philip A

Publication type:

journal article

Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects.

Published in:

2008

By:

Sharma, Neeraj K;
Das, Swapan K;
Mondal, Ashis K;
Hackney, Oksana G;
Chu, Winston S;
Kern, Philip A;
Rasouli, Neda;
Spencer, Horace J;
Yao-Borengasser, Aiwei;
Elbein, Steven C

Publication type:

journal article

Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferator-activated receptor-gamma responsiveness.

Published in:

2008

By:

Yao-Borengasser, Aiwei;
Rassouli, Negah;
Varma, Vijayalakshmi;
Bodles, Angela M;
Rasouli, Neda;
Unal, Resat;
Phanavanh, Bounleut;
Ranganathan, Gouri;
McGehee, Robert E Jr;
Kern, Philip A

Publication type:

journal article

Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Is Associated with Hyperinsulinemia and Insulin Resistance.

Published in:

Toxicological Sciences, 2000, v. 56, n. 2, p. 431, doi. 10.1093/toxsci/56.2.431

By:

Cranmer, Morris;
Louie, Shirley;
Kennedy, Richard H.;
Kern, Philip A.;
Fonseca, Vivian A.

Publication type:

Article

Senolytic treatment rescues blunted muscle hypertrophy in old mice.

Published in:

GeroScience, 2022, v. 44, n. 4, p. 1925, doi. 10.1007/s11357-022-00542-2

By:

Dungan, Cory M.;
Figueiredo, Vandre C.;
Wen, Yuan;
VonLehmden, Georgia L.;
Zdunek, Christopher J.;
Thomas, Nicholas T.;
Mobley, C. Brooks;
Murach, Kevin A.;
Brightwell, Camille R.;
Long, Douglas E.;
Fry, Christopher S.;
Kern, Philip A.;
McCarthy, John J.;
Peterson, Charlotte A.

Publication type:

Article

Associations of muscle lipid content with physical function and resistance training outcomes in older adults: altered responses with metformin.

Published in:

GeroScience, 2021, v. 43, n. 2, p. 629, doi. 10.1007/s11357-020-00315-9

By:

Long, Douglas E.;
Peck, Bailey D.;
Tuggle, Steven C.;
Villasante Tezanos, Alejandro G.;
Windham, Samuel T.;
Bamman, Marcas M.;
Kern, Philip A.;
Peterson, Charlotte A.;
Walton, Rosicka G.

Publication type:

Article

Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double‐blind, placebo‐controlled, multicenter trial: The MASTERS trial.

Published in:

Aging Cell, 2019, v. 18, n. 6, p. N.PAG, doi. 10.1111/acel.13039

By:

Walton, R. Grace;
Dungan, Cory M.;
Long, Douglas E.;
Tuggle, S. Craig;
Kosmac, Kate;
Peck, Bailey D.;
Bush, Heather M.;
Villasante Tezanos, Alejandro G.;
McGwin, Gerald;
Windham, Samuel T.;
Ovalle, Fernando;
Bamman, Marcas M.;
Kern, Philip A.;
Peterson, Charlotte A.

Publication type:

Article

Fibre type-specific satellite cell response to aerobic training in sedentary adults.

Published in:

Journal of Physiology, 2014, v. 592, n. 12, p. 2625, doi. 10.1113/jphysiol.2014.271288

By:

Fry, Christopher S.;
Noehren, Brian;
Mula, Jyothi;
Ubele, Margo F.;
Westgate, Philip M.;
Kern, Philip A.;
Peterson, Charlotte A.

Publication type:

Article

Human skeletal muscle macrophages increase following cycle training and are associated with adaptations that may facilitate growth.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37187-1

By:

Walton, R. Grace;
Kosmac, Kate;
Mula, Jyothi;
Fry, Christopher S.;
Peck, Bailey D.;
Groshong, Jason S.;
Finlin, Brian S.;
Zhu, Beibei;
Kern, Philip A.;
Peterson, Charlotte A.

Publication type:

Article

Saturated Fatty Acid Activates T Cell Inflammation Through a Nicotinamide Nucleotide Transhydrogenase (NNT)-Dependent Mechanism.

Published in:

Biomolecules (2218-273X), 2019, v. 9, n. 2, p. 79, doi. 10.3390/biom9020079

By:

McCambridge, Grace;
Agrawal, Madhur;
Keady, Alanna;
Kern, Philip A.;
Hasturk, Hatice;
Nikolajczyk, Barbara S.;
Bharath, Leena P.

Publication type:

Article

Fasting and Glucose Metabolism Differentially Impact Peripheral Inflammation in Human Type 2 Diabetes.

Published in:

Nutrients, 2024, v. 16, n. 10, p. 1404, doi. 10.3390/nu16101404

By:

Kalantar, Gabriella H.;
Saraswat, Shubh;
SantaCruz-Calvo, Sara;
Gholamrezaeinejad, Fatemeh;
Javidan, Aida;
Agrawal, Madhur;
Liu, Rui;
Kern, Philip A.;
Zhang, Xiaohua Douglas;
Nikolajczyk, Barbara S.

Publication type:

Article

A guide for using NIH Image J for single slice cross-sectional area and composition analysis of the thigh from computed tomography.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0211629

By:

Long, Douglas E.;
Villasante Tezanos, Alejandro G.;
Wise, James N.;
Kern, Philip A.;
Bamman, Marcas M.;
Peterson, Charlotte A.;
Dennis, Richard A.

Publication type:

Article

Regulation of Small Ubiquitin-Like Modifier-1, Nuclear Receptor Coreceptor, Histone Deacetylase 3, and Peroxisome Proliferator-Activated Receptor-γ in Human Adipose Tissue.

Published in:

Metabolic Syndrome & Related Disorders, 2012, v. 10, n. 4, p. 312, doi. 10.1089/met.2011.0121

By:

Finlin, Brian S.;
Bodles-Brakhop, Angela M.;
Yao-Borengasser, Aiwei;
Zhu, Beibei;
Starnes, Catherine P.;
McGehee, Robert E.;
Peterson, Charlotte A.;
Kern, Philip A.;
Rasouli, Neda

Publication type:

Article

Visceral Fat and Adiponectin: Associations with Insulin Resistance Are Tissue-Specific in Women.

Published in:

Metabolic Syndrome & Related Disorders, 2009, v. 7, n. 1, p. 61, doi. 10.1089/met.2008.0035

By:

Robert H. Coker;
Rick H. Williams;
Sophie E. Yeo;
Patrick M. Kortebein;
Don L. Bodenner;
Philip A. Kern;
William J. Evans

Publication type:

Article

Calcium Is Involved in Formation of High Molecular Weight Adiponectin.

Published in:

Metabolic Syndrome & Related Disorders, 2008, v. 6, n. 2, p. 103, doi. 10.1089/met.2007.0033

By:

Anannya Banga;
Angela M. Bodles;
Neda Rasouli;
Gouri Ranganathan;
Philip A. Kern;
Randall J. Owens

Publication type:

Article

The Value of Innovation to Implementation Program (VI<sup>2</sup>P): A strategic approach to aligning and leveraging academic research and clinical care missions.

Published in:

Learning Health Systems, 2019, v. 3, n. 4, p. N.PAG, doi. 10.1002/lrh2.10199

By:

Li, Jing;
Williams, Mark V.;
Page, Cecilia;
Cassis, Lisa;
Kern, Philip A.;
DiPaola, Robert S.

Publication type:

Article

In vivo analysis of γH2AX+ cells in skeletal muscle from aged and obese humans.

Published in:

FASEB Journal, 2020, v. 34, n. 5, p. 7018, doi. 10.1096/fj.202000111RR

By:

Dungan, Cory M.;
Peck, Bailey D.;
Walton, R. Grace;
Huang, Zhengyan;
Bamman, Marcas M.;
Kern, Philip A.;
Peterson, Charlotte A.

Publication type:

Article