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Sensitive multiplexed analysis of kinase activities and activity-based kinase identification.
Published in:
Nature Biotechnology, 2009, v. 27, n. 10, p. 933, doi. 10.1038/nbt.1566
By:
- Kubota, Kazuishi;
- Anjum, Rana;
- Yonghao Yu;
- Kunz, Ryan C.;
- Andersen, Jannik N.;
- Kraus, Manfred;
- Keilhack, Heike;
- Nagashima, Kumiko;
- Krauss, Stefan;
- Paweletz, Cloud;
- Hendrickson, Ronald C.;
- Feldman, Adam S.;
- Chin-Lee Wu;
- Rush, John;
- Villén, Judit;
- Gygi, Steven P.
Publication type:
Article
Synergistic Anti-Tumor Activity of EZH2 Inhibitors and Glucocorticoid Receptor Agonists in Models of Germinal Center Non-Hodgkin Lymphomas.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0111840
By:
- Knutson, Sarah K.;
- Warholic, Natalie M.;
- Johnston, L. Danielle;
- Klaus, Christine R.;
- Wigle, Tim J.;
- Iwanowicz, Dorothy;
- Littlefield, Bruce A.;
- Porter-Scott, Margaret;
- Smith, Jesse J.;
- Moyer, Mikel P.;
- Copeland, Robert A.;
- Pollock, Roy M.;
- Kuntz, Kevin W.;
- Raimondi, Alejandra;
- Keilhack, Heike
Publication type:
Article
Regulation of Brown Fat Adipogenesis by Protein Tyrosine Phosphatase 1B.
Published in:
PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016446
By:
- Matsuo, Kosuke;
- Bettaieb, Ahmed;
- Nagata, Naoto;
- Matsuo, Izumi;
- Keilhack, Heike;
- Haj, Fawaz G.
Publication type:
Article
Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule.
Published in:
ChemBioChem, 2021, v. 22, n. 12, p. 2107, doi. 10.1002/cbic.202100047
By:
- Wigle, Tim J.;
- Ren, Yue;
- Molina, Jennifer R.;
- Blackwell, Danielle J.;
- Schenkel, Laurie B.;
- Swinger, Kerren K.;
- Kuplast‐Barr, Kristy;
- Majer, Christina R.;
- Church, W. David;
- Lu, Alvin Z.;
- Mo, Jason;
- Abo, Ryan;
- Cheung, Anne;
- Dorsey, Bryan W.;
- Niepel, Mario;
- Perl, Nicholas R.;
- Vasbinder, Melissa M.;
- Keilhack, Heike;
- Kuntz, Kevin W.
Publication type:
Article
Correction: Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma.
Published in:
2017
By:
- Kawano, Satoshi;
- Grassian, Alexandra R.;
- Tsuda, Masumi;
- Knutson, Sarah K.;
- Warholic, Natalie M.;
- Kuznetsov, Galina;
- Xu, Shanqin;
- Xiao, Yonghong;
- Pollock, Roy M.;
- Smith, Jesse J.;
- Kuntz, Kevin W.;
- Ribich, Scott;
- Minoshima, Yukinori;
- Matsui, Junji;
- Copeland, Robert A.;
- Tanaka, Shinya;
- Keilhack, Heike
Publication type:
Correction Notice
Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma.
Published in:
PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0158888
By:
- Kawano, Satoshi;
- Grassian, Alexandra R.;
- Tsuda, Masumi;
- Knutson, Sarah K.;
- Warholic, Natalie M.;
- Kuznetsov, Galina;
- Xu, Shanqin;
- Xiao, Yonghong;
- Pollock, Roy M.;
- Smith, Jesse S.;
- Kuntz, Kevin K.;
- Ribich, Scott;
- Minoshima, Yukinori;
- Matsui, Junji;
- Copeland, Robert A.;
- Tanaka, Shinya;
- Keilhack, Heike
Publication type:
Article
Initial testing (stage 1) of tazemetostat (EPZ-6438), a novel EZH2 inhibitor, by the Pediatric Preclinical Testing Program.
Published in:
2017
By:
- Kurmasheva, Raushan T.;
- Sammons, Melissa;
- Favours, Edward;
- Wu, Jianwrong;
- Kurmashev, Dias;
- Cosmopoulos, Katherine;
- Keilhack, Heike;
- Klaus, Christine R.;
- Houghton, Peter J.;
- Smith, Malcolm A.
Publication type:
journal article
A687V EZH2 is a gain-of-function mutation found in lymphoma patients
Published in:
FEBS Letters, 2012, v. 586, n. 19, p. 3448, doi. 10.1016/j.febslet.2012.07.066
By:
- Majer, Christina R.;
- Jin, Lei;
- Scott, Margaret Porter;
- Knutson, Sarah K.;
- Kuntz, Kevin W.;
- Keilhack, Heike;
- Smith, Jesse J.;
- Moyer, Mikel P.;
- Richon, Victoria M.;
- Copeland, Robert A.;
- Wigle, Tim J.
Publication type:
Article
A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells.
Published in:
Nature Chemical Biology, 2012, v. 8, n. 11, p. 890, doi. 10.1038/nchembio.1084
By:
- Knutson, Sarah K;
- Wigle, Tim J;
- Warholic, Natalie M;
- Sneeringer, Christopher J;
- Allain, Christina J;
- Klaus, Christine R;
- Sacks, Joelle D;
- Raimondi, Alejandra;
- Majer, Christina R;
- Song, Jeffrey;
- Scott, Margaret Porter;
- Jin, Lei;
- Smith, Jesse J;
- Olhava, Edward J;
- Chesworth, Richard;
- Moyer, Mikel P;
- Richon, Victoria M;
- Copeland, Robert A;
- Keilhack, Heike;
- Pollock, Roy M
Publication type:
Article

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