Works by Keene, C. Dirk

Results: 171

Multidimensional MRI reveals cortical astrogliosis linked to dementia in Alzheimer's disease Open Access.

Published in:

Brain Communications, 2025, v. 7, n. 3, p. 1, doi. 10.1093/braincomms/fcaf245

By:

Barsoum, Stephanie;
Latimer, Caitlin S;
Nolan, Amber L;
Barrett, Alexander;
Chang, Koping;
Troncoso, Juan C;
Keene, C Dirk;
Benjamini, Dan

Publication type:

Article

Quantitative analysis of chondroitin sulfate disaccharides from human and rodent fixed brain tissue by electrospray ionization-tandem mass spectrometry.

Published in:

Glycobiology, 2019, v. 29, n. 12, p. 847, doi. 10.1093/glycob/cwz060

By:

Alonge, Kimberly M;
Logsdon, Aric F;
Murphree, Taylor A;
Banks, William A;
Keene, C Dirk;
Edgar, J Scott;
Whittington, Dale;
Schwartz, Michael W;
Guttman, Miklos

Publication type:

Article

Psychosis in Spinocerebellar Ataxias: a Case Series and Study of Tyrosine Hydroxylase in Substantia Nigra.

Published in:

Cerebellum, 2018, v. 17, n. 2, p. 143, doi. 10.1007/s12311-017-0882-5

By:

Turk, Katherine W.;
Flanagan, Margaret E.;
Josephson, Samuel;
Keene, C. Dirk;
Jayadev, Suman;
Bird, Thomas D.

Publication type:

Article

Data-independent acquisition proteomic analysis of the brain microvasculature in Alzheimer's disease identifies major pathways of dysfunction and upregulation of cytoprotective responses.

Published in:

Fluids & Barriers of the CNS, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12987-024-00581-1

By:

Erickson, Michelle A.;
Johnson, Richard S.;
Damodarasamy, Mamatha;
MacCoss, Michael J.;
Keene, C. Dirk;
Banks, William A.;
Reed, May J.

Publication type:

Article

Blood-Based Bioenergetic Profiling Reflects Differences in Brain Bioenergetics and Metabolism.

Published in:

Oxidative Medicine & Cellular Longevity, 2017, p. 1, doi. 10.1155/2017/7317251

By:

Tyrrell, Daniel J.;
Bharadwaj, Manish S.;
Jorgensen, Matthew J.;
Register, Thomas C.;
Shively, Carol;
Andrews, Rachel N.;
Neth, Bryan;
Dirk Keene, C.;
Mintz, Akiva;
Craft, Suzanne;
Molina, Anthony J. A.

Publication type:

Article

Leveraging Neuroimaging Tools to Assess Precision and Accuracy in an Alzheimer's Disease Neuropathologic Sampling Protocol.

Published in:

Frontiers in Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fnins.2021.693242

By:

Webster, Jason M.;
Grabowski, Thomas J.;
Madhyastha, Tara M.;
Gibbons, Laura E.;
Keene, C. Dirk;
Latimer, Caitlin S.

Publication type:

Article

Neuropathological correlates of vulnerability and resilience in the cerebellum in Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 2, p. 1, doi. 10.1002/alz.14428

By:

Samstag, Colby L.;
Chapman, Nicola H.;
Gibbons, Laura E.;
Geller, Julianne;
Loeb, Nicholas;
Dharap, Siddhant;
Yagi, Mayumi;
Cook, David G.;
Pagulayan, Kathleen F.;
Crane, Paul K.;
Larson, Eric B.;
Wijsman, Ellen M.;
Latimer, Caitlin S.;
Bird, Thomas D.;
Keene, C. Dirk;
Carlson, Erik S.

Publication type:

Article

The Consortium for Clarity in ADRD Research Through Imaging (CLARiTI).

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 1, p. 1, doi. 10.1002/alz.14383

By:

Mormino, Elizabeth C.;
Biber, Sarah A.;
Rahman‐Filipiak, Annalise;
Arfanakis, Konstantinos;
Clark, Lindsay;
Dage, Jeffrey L.;
Detre, John A.;
Dickerson, Bradford C.;
Donohue, Michael C.;
Kecskemeti, Steven;
Hohman, Timothy J.;
Jagust, William J.;
Keene, Dirk C.;
Kukull, Walter;
Levendovszky, Swati R.;
Rosen, Howie;
Thompson, Paul M.;
Villemagne, Victor L.;
Wolk, David A.;
Okonkwo, Ozioma C.

Publication type:

Article

Novel rare variant associations with late‐life cognitive performance.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.095364

By:

Regelson, Alexandra N.;
Archer, Derek B.;
Durant, Alaina;
Mukherjee, Shubhabrata;
Lee, Michael L.;
Choi, Seo‐Eun;
Scollard, Phoebe;
Trittschuh, Emily H.;
Mez, Jesse;
Bush, William S.;
Kuzma, Amanda B;
Cuccaro, Michael L.;
Cruchaga, Carlos;
Farrer, Lindsay A.;
Wang, Li‐San;
Schellenberg, Gerard D.;
Mayeux, Richard;
Kukull, Walter A.;
Keene, C. Dirk;
Saykin, Andrew J.

Publication type:

Article

A digital brain sampling protocol atlas to simplify and accelerate biorepository tissue requests.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.093542

By:

Webster, Jason;
Shojaie, Ali;
Shen, Yiqin Alicia;
Le, Tung;
MacDonald, Christine;
Latimer, Caitlin S;
Keene, C Dirk;
Grabowski, Thomas J

Publication type:

Article

Electrophysiological insights into resilient individuals: Examining calcium permeable AMPA receptor responses and neuropathological correlations in Alzheimer's Disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.093208

By:

Gutierrez, Berenice A;
Moreno, Naomi;
Keene, C Dirk;
Limon, Agenor

Publication type:

Article

A systems‐biology approach to identify candidate genes associated with composite brain pathology scores in the Adult Changes of Thought (ACT) and the Religious Orders Study and Memory and Aging Project (ROSMAP) autopsy cohorts.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.093129

By:

Dutta, Aheli;
Broome, Jai;
Sinha, Sagnik;
Gibbons, Laura E.;
Shade, Lincoln MP;
Katsumata, Yuriko;
Travaglini, Kyle J;
Gabitto, Mariano I;
Zhao, Zijie;
Lu, Qiongshi;
Schneider, Julie A.;
Latimer, Caitlin S;
Keene, C Dirk;
Crane, Paul K.;
Fardo, David W.;
Mukherjee, Shubhabrata

Publication type:

Article

Genetically predicted levels of sex hormones are associated with cerebrovascular disease pathology in the Alzheimer's disease brain.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.092453

By:

Libby, Julia B.;
Beecham, Gary;
Montine, Thomas J.;
Toga, Arthur W.;
Cuccaro, Michael L.;
Keene, C Dirk;
Larson, Eric B;
Crane, Paul K.;
Mukherjee, Shubhabrata;
Panizzon, Matthew S.;
Biber, Sarah A;
Kukull, Walter A.;
Bennett, David A.;
Schneider, Julie A.;
Barnes, Lisa L.;
De Jager, Philip L.;
Menon, Vilas;
Hohman, Timothy J.;
Dumitrescu, Logan C.

Publication type:

Article

Sex Specific Association of Apolipoprotein E Alleles with Autopsy Measures of Arteriolosclerosis and Atherosclerosis among Older Adults.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.091485

By:

Gomez, Melisa Lara;
Beecham, Gary;
Montine, Thomas J.;
Cuccaro, Michael L.;
Toga, Arthur W.;
Keene, C Dirk;
Crane, Paul K.;
Mukherjee, Shubhabrata;
Panizzon, Matthew S.;
Biber, Sarah A;
Kukull, Walter A.;
Bennett, David A.;
Barnes, Lisa L.;
Schneider, Julie A.;
De Jager, Philip L.;
Menon, Vilas;
Hohman, Timothy J.;
Dumitrescu, Logan C.

Publication type:

Article

Multimodal Genetic Analysis of Brain Amyloidosis.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.090566

By:

Wang, Ting‐Chen;
Archer, Derek B.;
Ali, Muhammad;
Wu, Yiyang;
Mormino, Elizabeth;
Buckley, Rachel F.;
Lee, Annie J.;
Saykin, Andrew J.;
De Jager, Philip L.;
Schneider, Julie A.;
Bennett, David A.;
Barnes, Lisa L.;
Vardarajan, Badri N.;
Mayeux, Richard;
Kunkle, Brian W.;
Bush, William S.;
Keene, C. Dirk;
Seshadri, Sudha;
Sperling, Reisa A;
Vemuri, Prashanthi

Publication type:

Article

Spatial proteome profiling for distinguishing tangle‐bearing neurons and their microenvironments from healthy neurons in Alzheimer's disease brains.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.089552

By:

Dehkordi, Shiva Kazempour;
Orr, Timothy C.;
Bodamer, Ryan H;
Hudson, Hannah R.;
Sun, Victoria;
Keene, C Dirk;
Zare, Habil;
Orr, Miranda E.

Publication type:

Article

An endolysosome pathway specific polygenic risk score for Alzheimer Disease predicts cell‐type specific transcriptomic and morphological phenotypes.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.087986

By:

Prater, Katherine E;
Rose, Shannon;
Johnson, Corbin S.C.;
Strohbehn, Sam;
Cochoit, Alexandra J;
Mamde, Sainath;
Sun, Wei;
Keene, C. Dirk;
Shojaie, Ali;
Garden, Gwenn A;
Blue, Elizabeth E;
Young, Jessica E.;
Jayadev, Suman

Publication type:

Article

A Novel platform for precision quantitative analyses of neuropathology in Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.087480

By:

Keene, C Dirk

Publication type:

Article

pTau‐associated gene expression signatures in the middle temporal gyrus.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.085234

By:

Rachleff, Victoria M;
Mahoney, Joseph T;
Travaglini, Kyle J;
Gabitto, Mariano I;
Hodge, Rebecca D;
Keene, C Dirk;
Lein, Ed S

Publication type:

Article

Suppression of eEF2 phosphorylation alleviates synaptic failure and cognitive deficits in mouse models of Down syndrome.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5357, doi. 10.1002/alz.13916

By:

Wang, Xin;
Yang, Qian;
Zhou, Xueyan;
Keene, C. Dirk;
Ryazanov, Alexey G.;
Ma, Tao

Publication type:

Article

Lewy body pathology modifies risk factors for cerebral amyloid angiopathy when comorbid with Alzheimer's disease pathology.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2564, doi. 10.1002/alz.13704

By:

Pillai, Jagan A.;
Bena, James;
Tousi, Babak;
Rothenberg, Kasia;
Keene, C. Dirk;
Leverenz, James B.

Publication type:

Article

APOE loss‐of‐function variants: Compatible with longevity and associated with resistance to Alzheimer's Disease pathology.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082628

By:

Guen, Yann Le;
Chemparathy, Augustine;
Chen, Sunny;
Leong, Lesley;
Gorzynski, John John;
Xue, Guangxue;
Belloy, Michael E;
Kasireddy, Nandita;
Tauber, Andres Peña;
Williams, Kennedy;
Wingo, Thomas S.;
Lah, James J.;
Jayadev, Suman;
Hales, Chadwick M;
Peskind, Elaine R;
Child, Daniel D;
Keene, C Dirk;
Le, Cong;
Ashley, Euan;
Yu, Chang‐En

Publication type:

Article

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy.

Published in:

PLoS Genetics, 2019, v. 15, n. 12, p. 1, doi. 10.1371/journal.pgen.1008526

By:

Liachko, Nicole F.;
Saxton, Aleen D.;
McMillan, Pamela J.;
Strovas, Timothy J.;
Keene, C. Dirk;
Bird, Thomas D.;
Kraemer, Brian C.

Publication type:

Article

Pluripotency of mesenchymal stem cells derived from adult marrow.

Published in:

2007

By:

Yuehua Jiang;
Jahagirdar, Balkrishna N.;
Reinhardt, R. Lee;
Schwartz, Robert E.;
Keene, C. Dirk;
Ortiz-Gonzalez, Xilma R.;
Reyes, Morayma;
Lenvik, Todd;
Lund, Troy;
Blackstad, Mark;
Du, Jingbo;
Aldrich, Sara;
Lisberg, Aaron;
Low, Walter C.;
Largaespada, David A.;
Verfaillie, Catherine M.

Publication type:

Correction Notice

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.

Published in:

JAMA Neurology, 2018, v. 75, n. 8, p. 989, doi. 10.1001/jamaneurol.2018.0821

By:

Hohman, Timothy J.;
Dumitrescu, Logan;
Barnes, Lisa L.;
Thambisetty, Madhav;
Beecham, Gary;
Kunkle, Brian;
Gifford, Katherine A.;
Bush, William S.;
Chibnik, Lori B.;
Mukherjee, Shubhabrata;
De Jager, Philip L.;
Kukull, Walter;
Crane, Paul K.;
Resnick, Susan M.;
Keene, C. Dirk;
Montine, Thomas J.;
Schellenberg, Gerard D.;
Haines, Jonathan L.;
Zetterberg, Henrik;
Blennow, Kaj

Publication type:

Article

Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings.

Published in:

JAMA Neurology, 2016, v. 73, n. 9, p. 1062, doi. 10.1001/jamaneurol.2016.1948

By:

Crane, Paul K.;
Gibbons, Laura E.;
Dams-O'Connor, Kristen;
Trittschuh, Emily;
Leverenz, James B.;
Keene, C. Dirk;
Sonnen, Joshua;
Montine, Thomas J.;
Bennett, David A.;
Leurgans, Sue;
Schneider, Julie A.;
Larson, Eric B.

Publication type:

Article

Hereditary spastic paraplegia with thin corpus callosum and SPG11 mutation: A neuropathological evaluation.

Published in:

Neuropathology, 2025, v. 45, n. 2, p. 123, doi. 10.1111/neup.13007

By:

Scherpelz, Kathryn P.;
Yoda, Rebecca A.;
Jayadev, Suman;
Davis, Marie Y.;
Hincks, Joshua C.;
Liachko, Nicole F.;
Bragg, Robert M.;
Cochoit, Alexa;
MacDonald, Christine L.;
Keene, C. Dirk;
Bird, Thomas D.;
Latimer, Caitlin S.

Publication type:

Article

Spinal cord‐predominant neuropathology in an adult‐onset case of POLR3A‐related spastic ataxia.

Published in:

Neuropathology, 2022, v. 42, n. 1, p. 58, doi. 10.1111/neup.12775

By:

Sytsma, Trevor M.;
Chen, Dong‐Hui;
Rolf, Bradley;
Dorschner, Michael;
Jayadev, Suman;
Keene, C. Dirk;
Zhang, Jing;
Bird, Thomas D.;
Latimer, Caitlin S.

Publication type:

Article

Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30785-8

By:

Jhanji, Megha;
Rao, Chintada Nageswara;
Massey, Jacob C.;
Hope III, Marion C.;
Zhou, Xueyan;
Keene, C. Dirk;
Ma, Tao;
Wyatt, Michael D.;
Stewart, Jason A.;
Sajish, Mathew

Publication type:

Article

Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer's disease.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22742-8

By:

Lauterborn, Julie C.;
Scaduto, Pietro;
Cox, Conor D.;
Schulmann, Anton;
Lynch, Gary;
Gall, Christine M.;
Keene, C. Dirk;
Limon, Agenor

Publication type:

Article

Redefining transcriptional regulation of the APOE gene and its association with Alzheimer's disease.

Published in:

PLoS ONE, 2020, v. 15, n. 1, p. 1, doi. 10.1371/journal.pone.0227667

By:

Lee, Eun-Gyung;
Tulloch, Jessica;
Chen, Sunny;
Leong, Lesley;
Saxton, Aleen D.;
Kraemer, Brian;
Darvas, Martin;
Keene, C. Dirk;
Shutes-David, Andrew;
Todd, Kaitlin;
Millard, Steve;
Yu, Chang-En

Publication type:

Article

Application of deep learning to understand resilience to Alzheimer's disease pathology.

Published in:

Brain Pathology, 2021, v. 31, n. 6, p. 1, doi. 10.1111/bpa.12974

By:

Lee, Cecilia S.;
Latimer, Caitlin S.;
Henriksen, Jonathan C.;
Blazes, Marian;
Larson, Eric B.;
Crane, Paul K.;
Keene, C. Dirk;
Lee, Aaron Y.

Publication type:

Article

Neuronal susceptibility to beta‐amyloid toxicity and ischemic injury involves histone deacetylase‐2 regulation of endophilin‐B1.

Published in:

Brain Pathology, 2019, v. 29, n. 2, p. 164, doi. 10.1111/bpa.12647

By:

Wang, David B.;
Kinoshita, Chizuru;
Kinoshita, Yoshito;
Sopher, Bryce L.;
Uo, Takuma;
Lee, Rona J.;
Kim, Joon Kyu;
Murphy, Sean P.;
Dirk Keene, C.;
Garden, Gwenn A.;
Morrison, Richard S.

Publication type:

Article

Novel Antibody Capture Assay for Paraffin-Embedded Tissue Detects Wide-Ranging Amyloid Beta and Paired Helical Filament-Tau Accumulation in Cognitively Normal Older Adults.

Published in:

Brain Pathology, 2012, v. 22, n. 4, p. 472, doi. 10.1111/j.1750-3639.2011.00542.x

By:

Postupna, Nadia;
Rose, Shannon E.;
Bird, Thomas D.;
Gonzalez-Cuyar, Luis F.;
Sonnen, Joshua A.;
Larson, Eric B.;
Keene, C. Dirk;
Montine, Thomas J.

Publication type:

Article

Ellsworth “Buster” Alvord (1923–2010).

Published in:

2010

By:

Keene, C. Dirk;
Swanson, Kristin R.;
Jing Zhang;
Cheng-Mei Shaw;
Montine, Thomas J.

Publication type:

Obituary

Impaired Eukaryotic Elongation Factor 1A Expression in Alzheimer's Disease.

Published in:

Neurodegenerative Diseases, 2016, v. 16, n. 1/2, p. 39, doi. 10.1159/000438925

By:

Beckelman, Brenna C.;
Zhou, Xueyan;
Keene, C. Dirk;
Ma, Tao

Publication type:

Article

Biomarkers for Alzheimer's disease.

Published in:

Expert Review of Neurotherapeutics, 2007, v. 7, n. 8, p. 1021, doi. 10.1586/14737175.7.8.1021

By:

Sonnen, Joshua A.;
Keene, C. Dirk;
Montine, Kathleen S.;
Ge Li;
Peskind, Elaine R.;
Jing Zhang;
Montine, Thomas J.

Publication type:

Article

Transcriptomic Profiles of Sepsis in the Human Brain.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2020, v. 201, n. 7, p. 861, doi. 10.1164/rccm.201909-1713LE

By:

Bustamante, Angela C.;
Opron, Kristopher;
Ehlenbach, William J.;
Larson, Eric B.;
Crane, Paul K.;
Dirk Keene, C.;
Standiford, Theodore J.;
Singer, Benjamin H.

Publication type:

Article

Transcriptomic Profiles of Sepsis in the Human Brain.

Published in:

2020

By:

Bustamante, Angela C;
Opron, Kristopher;
Ehlenbach, William J;
Larson, Eric B;
Crane, Paul K;
Keene, C Dirk;
Standiford, Theodore J;
Singer, Benjamin H

Publication type:

Letter

Satellite microglia: marker of traumatic brain injury and regulator of neuronal excitability.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-024-03328-9

By:

Feichtenbiner, Alicia B.;
Sytsma, Karinn;
O'Boyle, Ryan P.;
Mittenzwei, Rhonda;
Maioli, Heather;
Scherpelz, Kathryn P.;
Child, Daniel D.;
Li, Ning;
Ariza Torres, Jeanelle;
Keene, Lisa;
Kirkland, Amanda;
Howard, Kimberly;
Latimer, Caitlin;
Keene, C. Dirk;
Ransom, Christopher;
Nolan, Amber L.

Publication type:

Article

Brain-specific repression of AMPKα1 alleviates pathophysiology in Alzheimer's model mice.

Published in:

2020

By:

Zimmermann, Helena R.;
Yang, Wenzhong;
Kasica, Nicole P.;
Zhou, Xueyan;
Wang, Xin;
Beckelman, Brenna C.;
Lee, Jingyun;
Furdui, Cristina M.;
Keene, C. Dirk;
Ma, Tao

Publication type:

journal article

Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice.

Published in:

2019

By:

Beckelman, Brenna C.;
Wenzhong Yang;
Kasica, Nicole P.;
Zimmermann, Helena R.;
Xueyan Zhou;
Keene, C. Dirk;
Ryazanov, Alexey G.;
Tao Ma;
Yang, Wenzhong;
Zhou, Xueyan;
Ma, Tao

Publication type:

journal article

Aging‐related Alzheimer's disease‐like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus).

Published in:

American Journal of Primatology, 2021, v. 83, n. 11, p. 1, doi. 10.1002/ajp.23260

By:

Frye, Brett M.;
Craft, Suzanne;
Latimer, Caitlin S.;
Keene, C. Dirk;
Montine, Thomas J.;
Register, Thomas C.;
Orr, Miranda E.;
Kavanagh, Kylie;
Macauley, Shannon L.;
Shively, Carol A.

Publication type:

Article

Patterns of CAG repeat instability in the central nervous system and periphery in Huntington's disease and in spinocerebellar ataxia type 1.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 15, p. 2551, doi. 10.1093/hmg/ddaa139

By:

Pinto, Ricardo Mouro;
Arning, Larissa;
Giordano, James V;
Razghandi, Pedram;
Andrew, Marissa A;
Gillis, Tammy;
Correia, Kevin;
Mysore, Jayalakshmi S;
Urtubey, Debora-M Grote;
Parwez, Constanze R;
Hein, Sarah M von;
Clark, H Brent;
Nguyen, Huu Phuc;
Förster, Eckart;
Beller, Allison;
Jayadaev, Suman;
Keene, C Dirk;
Bird, Thomas D;
Lucente, Diane;
Vonsattel, Jean-Paul

Publication type:

Article

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration.

Published in:

Molecular Neurodegeneration, 2018, v. 13, p. 1, doi. 10.1186/s13024-018-0237-9

By:

Taylor, Laura M.;
McMillan, Pamela J.;
Liachko, Nicole F.;
Strovas, Timothy J.;
Ghetti, Bernardino;
Bird, Thomas D.;
Dirk Keene, C.;
Kraemer, Brian C.

Publication type:

Article

Adipocyte-Derived Small Extracellular Vesicles from Patients with Alzheimer Disease Carry miRNAs Predicted to Target the CREB Signaling Pathway in Neurons.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 14024, doi. 10.3390/ijms241814024

By:

Batabyal, Rachael A.;
Bansal, Ankush;
Cechinel, Laura Reck;
Authelet, Kayla;
Goldberg, Madeleine;
Nadler, Evan;
Keene, C. Dirk;
Jayadev, Suman;
Domoto-Reilly, Kimiko;
Li, Gail;
Peskind, Elaine;
Hashimoto-Torii, Kazue;
Buchwald, Dedra;
Freishtat, Robert J.

Publication type:

Article

APOE genotype-dependent modulation of astrocyte chemokine CCL3 production.

Published in:

Glia (0894-1491), 2015, v. 63, n. 1, p. 51, doi. 10.1002/glia.22732

By:

Cudaback, Eiron;
Yang, Yue;
Montine, Thomas J.;
Keene, C. Dirk

Publication type:

Article

Suppressed microglial E prostanoid receptor 1 signaling selectively reduces tumor necrosis factor alpha and interleukin 6 secretion from toll-like receptor 3 activation.

Published in:

Glia (0894-1491), 2011, v. 59, n. 4, p. 569, doi. 10.1002/glia.21125

By:

Li, Xianwu;
Cudaback, Eiron;
Keene, C. Dirk;
Breyer, Richard M.;
Montine, Thomas J.

Publication type:

Article

A single-cell based precision medicine approach using glioblastoma patient-specific models.

Published in:

NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-022-00294-4

By:

Park, James H.;
Feroze, Abdullah H.;
Emerson, Samuel N.;
Mihalas, Anca B.;
Keene, C. Dirk;
Cimino, Patrick J.;
de Lomana, Adrian Lopez Garcia;
Kannan, Kavya;
Wu, Wei-Ju;
Turkarslan, Serdar;
Baliga, Nitin S.;
Patel, Anoop P.

Publication type:

Article

Multispectral LEDs Eliminate Lipofuscin-Associated Autofluorescence for Immunohistochemistry and CD44 Variant Detection by in Situ Hybridization in Aging Human, non-Human Primate, and Murine Brain.

Published in:

ASN Neuro, 2022, p. 1, doi. 10.1177/17590914221123138

By:

Adeniyi, Philip A.;
Fopiano, Katie-Anne;
Banine, Fatima;
Garcia, Mariel;
Gong, Xi;
Keene, C. Dirk;
Sherman, Larry S.;
Bagi, Zsolt;
Back, Stephen A.

Publication type:

Article