Works by Keely, Patricia J

Results: 31

A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys.

Published in:

Aging Cell, 2013, v. 12, n. 4, p. 672, doi. 10.1111/acel.12091

By:

Pugh, Thomas D.;
Conklin, Matthew W.;
Evans, Trent D.;
Polewski, Michael A.;
Barbian, Hannah J.;
Pass, Rachelle;
Anderson, Bradley D.;
Colman, Ricki J.;
Eliceiri, Kevin W.;
Keely, Patricia J.;
Weindruch, Richard;
Beasley, T. Mark;
Anderson, Rozalyn M.

Publication type:

Article

Why the stroma matters in breast cancer.

Published in:

Cell Adhesion & Migration, 2012, v. 6, n. 3, p. 249, doi. 10.4161/cam.20567

By:

Conklin, Matthew W.;
Keely, Patricia J.

Publication type:

Article

The role of focal adhesion kinase in tumor initiation and progression.

Published in:

Cell Adhesion & Migration, 2009, v. 3, n. 4, p. 347, doi. 10.4161/cam.3.4.9458

By:

Provenzano, Paolo P.;
Keely, Patricia J.

Publication type:

Article

ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix.

Published in:

Journal of Cell Biology, 2003, v. 163, n. 3, p. 583, doi. 10.1083/jcb.200305010

By:

Wozniak, Michele A.;
Desai, Radhika;
Solski, Patricia A.;
Der, Channing J.;
Keely, Patricia J.

Publication type:

Article

The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis.

Published in:

Nature Cell Biology, 2013, v. 15, n. 6, p. 677, doi. 10.1038/ncb2743

By:

Zhang, Kun;
Corsa, Callie A.;
Ponik, Suzanne M.;
Prior, Julie L.;
Piwnica-Worms, David;
Eliceiri, Kevin W.;
Keely, Patricia J.;
Longmore, Gregory D.

Publication type:

Article

Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130<sup>cas</sup>.

Published in:

Nature Cell Biology, 1999, v. 1, n. 8, p. 507, doi. 10.1038/70302

By:

Eisenmann, Kathryn M.;
McCarthy, James B.;
Simpson, Melanie A.;
Keely, Patricia J.;
Guan, Jun-Lin;
Tachibana, Kouichi;
Lim, Louis;
Manser, Ed;
Furcht, Leo T.;
Iida, Joji

Publication type:

Article

Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer.

Published in:

EMBO Molecular Medicine, 2016, v. 8, n. 4, p. 388, doi. 10.15252/emmm.201606273

By:

Takabatake, Yukie;
Oxvig, Claus;
Nagi, Chandandeep;
Adelson, Kerin;
Jaffer, Shabnam;
Schmidt, Hank;
Keely, Patricia J;
Eliceiri, Kevin W;
Mandeli, John;
Germain, Doris

Publication type:

Article

Autofluorescence Spectroscopy of Normal and Malignant Human Breast Cell Lines.

Published in:

Photochemistry & Photobiology, 2003, v. 78, n. 5, p. 462, doi. 10.1562/0031-8655(2003)0780462ASONAM2.0.CO2

By:

Palmer, Gregory M.;
Keely, Patricia J.;
Breslin, Tara M.;
Ramanujam, Nirmala

Publication type:

Article

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2.

Published in:

Nature Medicine, 2011, v. 17, n. 9, p. 1109, doi. 10.1038/nm.2416

By:

Lyons, Traci R;
O'Brien, Jenean;
Borges, Virginia F;
Conklin, Matthew W;
Keely, Patricia J;
Eliceiri, Kevin W;
Marusyk, Andriy;
Tan, Aik-Choon;
Schedin, Pepper

Publication type:

Article

R-Ras regulates β<sub>1</sub>-integrin trafficking via effects on membrane ruffling and endocytosis.

Published in:

BMC Cell Biology, 2010, v. 11, p. 1, doi. 10.1186/1471-2121-11-14

By:

Conklin, Matthew W.;
Ada-Nguema, Aude;
Parsons, Maddy;
Riching, Kristin M.;
Keely, Patricia J.

Publication type:

Article

Review of quantitative multiscale imaging of breast cancer.

Published in:

Journal of Medical Imaging, 2018, v. 5, n. 1, p. 010901-1, doi. 10.1117/1.JMI.5.1.010901

By:

Pinkert, Michael A.;
Salkowski, Lonie R.;
Keely, Patricia J.;
Hall, Timothy J.;
Block, Walter F.;
Eliceiri, Kevin W.

Publication type:

Article

Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells.

Published in:

2017

By:

Barcus, Craig E.;
O'Leary, Kathleen A.;
Brockman, Jennifer L.;
Rugowski, Debra E.;
Yuming Liu;
Garcia, Nancy;
Menggang Yu;
Keely, Patricia J.;
Eliceiri, Kevin W.;
Schuler, Linda A.;
Liu, Yuming;
Yu, Menggang

Publication type:

journal article

An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis.

Published in:

Journal of Cell Biology, 2006, v. 174, n. 7, p. 1047, doi. 10.1083/jcb.200603152

By:

Pal, Saumen;
Jing Wu;
Murray, Justin K.;
Gellman, Samuel H.;
Wozniak, Michele A.;
Keely, Patricia J.;
Boyer, Meghan E.;
Gomez, Timothy M.;
Hasso, Sean M.;
Fallon, John F.;
Bresnick, Emery H.

Publication type:

Article

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through Pl(3)K.

Published in:

Nature, 1997, v. 390, n. 6660, p. 632, doi. 10.1038/37656

By:

Keely, Patricia J.;
Westwick, John K.

Publication type:

Article

Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness.

Published in:

Journal of Cell Biology, 2016, v. 212, n. 6, p. 707, doi. 10.1083/jcb.201507054

By:

Lily Thao-Nhi Le;
Cazares, Oscar;
Mouw, Janna K.;
Chatterjee, Sharmila;
Macias, Hector;
Moran, Angel;
Ramos, Jillian;
Keely, Patricia J.;
Weaver, Valerie M.;
Hinck, Lindsay

Publication type:

Article

Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31126-w

By:

Tomko, Lucas A.;
Hill, Ryan C.;
Barrett, Alexander;
Szulczewski, Joseph M.;
Conklin, Matthew W.;
Eliceiri, Kevin W.;
Keely, Patricia J.;
Hansen, Kirk C.;
Ponik, Suzanne M.

Publication type:

Article

Multi-Modal Investigation of Metabolism in Murine Breast Cancer Cell Lines Using Fluorescence Lifetime Microscopy and Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopy.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 10, p. 550, doi. 10.3390/metabo14100550

By:

Erickson-Bhatt, Sarah;
Cox, Benjamin L.;
Macdonald, Erin;
Chacko, Jenu V.;
Begovatz, Paul;
Keely, Patricia J.;
Ponik, Suzanne M.;
Eliceiri, Kevin W.;
Fain, Sean B.

Publication type:

Article

In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging.

Published in:

Scientific Reports, 2016, p. 25086, doi. 10.1038/srep25086

By:

Szulczewski, Joseph M.;
Inman, David R.;
Entenberg, David;
Ponik, Suzanne M.;
Aguirre-Ghiso, Julio;
Castracane, James;
Condeelis, John;
Eliceiri, Kevin W.;
Keely, Patricia J.

Publication type:

Article

Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects.

Published in:

Integrative Biology, 2011, v. 3, n. 4, p. 439, doi. 10.1039/c0ib00063a

By:

Sung, Kyung Eun;
Yang, Ning;
Pehlke, Carolyn;
Keely, Patricia J.;
Eliceiri, Kevin W.;
Friedl, Andreas;
Beebe, David J.

Publication type:

Article

Mammary collagen architecture and its association with mammographic density and lesion severity among women undergoing image-guided breast biopsy.

Published in:

2021

By:

Bodelon, Clara;
Mullooly, Maeve;
Pfeiffer, Ruth M.;
Fan, Shaoqi;
Abubakar, Mustapha;
Lenz, Petra;
Vacek, Pamela M.;
Weaver, Donald L.;
Herschorn, Sally D.;
Johnson, Jason M.;
Sprague, Brian L.;
Hewitt, Stephen;
Shepherd, John;
Malkov, Serghei;
Keely, Patricia J.;
Eliceiri, Kevin W.;
Sherman, Mark E.;
Conklin, Matthew W.;
Gierach, Gretchen L.

Publication type:

journal article

Dense Collagen-I Matrices Enhance Pro-Tumorigenic Estrogen-Prolactin Crosstalk in MCF-7 and T47D Breast Cancer Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 1, p. 1, doi. 10.1371/journal.pone.0116891

By:

Barcus, Craig E.;
Holt, Elizabeth C.;
Keely, Patricia J.;
Eliceiri, Kevin W.;
Schuler, Linda A.

Publication type:

Article

A Three-Dimensional Computational Model of Collagen Network Mechanics.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0111896

By:

Lee, Byoungkoo;
Zhou, Xin;
Riching, Kristin;
Eliceiri, Kevin W.;
Keely, Patricia J.;
Guelcher, Scott A.;
Weaver, Alissa M.;
Jiang, Yi

Publication type:

Article

Computational segmentation of collagen fibers from second-harmonic generation images of breast cancer.

Published in:

Journal of Biomedical Optics, 2014, v. 19, n. 1, p. 1, doi. 10.1117/1.JBO.19.1.016007

By:

Bredfeldt, Jeremy S.;
Yuming Liu;
Pehlke, Carolyn A.;
Conklin, Matthew W.;
Szulczewski, Joseph M.;
Inman, David R.;
Keely, Patricia J.;
Nowak, Robert D.;
Mackie, Thomas R.;
Eliceiri, Kevin W.

Publication type:

Article

Nonlinear optical imaging and spectral-lifetime computational analysis of endogenous and exogenous fluorophores in breast cancer.

Published in:

Journal of Biomedical Optics, 2008, v. 13, n. 3, p. 31220, doi. 10.1117/1.2940365

By:

Paolo P. Provenzano;
Curtis T. Rueden;
Steve M. Trier;
Long Yan;
Suzanne M. Ponik;
David R. Inman;
Patricia J. Keely;
Kevin W. Eliceiri

Publication type:

Article

In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia.

Published in:

Journal of Biomedical Optics, 2007, v. 12, n. 2, p. 24014, doi. 10.1117/1.2717503

By:

Melissa C. Skala;
Kristin M. Riching;
Damian K. Bird;
Annette Gendron-Fitzpatrick;
Jens Eickhoff;
Kevin W. Eliceiri;
Patricia J. Keely;
Nirmala Ramanujam

Publication type:

Article

LPS Modulates Rhinovirus-Induced Chemokine Secretion in Monocytes and Macrophages.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2014, v. 51, n. 1, p. 125, doi. 10.1165/rcmb.2013-0404OC

By:

Karta, Maya R.;
Gavala, Monica L.;
Curran, Colleen S.;
Wickert, Lisa E.;
Keely, Patricia J.;
Gern, James E.;
Bertics, Paul J.

Publication type:

Article

R-Ras Promotes Focal Adhesion Formation through Focal Adhesion Kinase and p130[sup Cas] by a Novel Mechanism That Differs From Integrins.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 3, p. 933, doi. 10.1128/MCB.23.3.933-949.2003

By:

Kwong, Lina;
Wozniak, Michele A.;
Collins, Asha S.;
Wilson, Siobhan D.;
Keely, Patricia J.

Publication type:

Article

Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment.

Published in:

2016

By:

García-Mendoza, María G.;
Inman, David R.;
Ponik, Suzanne M.;
Jeffery, Justin J.;
Sheerar, Dagna S.;
Van Doorn, Rachel R.;
Keely, Patricia J.

Publication type:

journal article

The importance of being a lumen.

Published in:

FASEB Journal, 2014, v. 28, n. 11, p. 4583, doi. 10.1096/fj.13-243733

By:

Bischel, Lauren L.;
Kyung E. Sung;
Jiménez-Torres, José A.;
Mader, Brianah;
Keely, Patricia J.;
Beebe, David J.

Publication type:

Article

Collagen density promotes mammary tumor initiation and progression.

Published in:

BMC Medicine, 2008, v. 6, p. 1, doi. 10.1186/1741-7015-6-11

By:

Provenzano, Paolo P.;
Inman, David R.;
Eliceiri, Kevin W.;
Knittel, Justin G.;
Yan, Long;
Rueden, Curtis T.;
White, John G.;
Keely, Patricia J.

Publication type:

Article

Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.

Published in:

2020

By:

Northey, Jason J.;
Barrett, Alexander S.;
Acerbi, Irene;
Hayward, Mary-Kate;
Talamantes, Stephanie;
Dean, Ivory S.;
Mouw, Janna K.;
Ponik, Suzanne M.;
Lakins, Jonathon N.;
Po-Jui Huang;
Junmin Wu;
Quanming Shi;
Samson, Susan;
Keely, Patricia J.;
Mukhtar, Rita A.;
Liphardt, Jan T.;
Shepherd, John A.;
Hwang, E. Shelley;
Yunn-Yi Chen;
Hansen, Kirk C.

Publication type:

journal article