Works matching AU Kearney, Jennifer A.

Results: 53

CACNA1H variants are not a cause of monogenic epilepsy.

Published in:

Human Mutation, 2020, v. 41, n. 6, p. 1138, doi. 10.1002/humu.24017

By:

Calhoun, Jeffrey D.;
Huffman, Alexandra M.;
Bellinski, Irena;
Kinsley, Lisa;
Bachman, Elizabeth;
Gerard, Elizabeth;
Kearney, Jennifer A.;
Carvill, Gemma L.

Publication type:

Article

Preclinical Evidence for a Drug–Drug Interaction Between Cannabinol and Melatonin.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2025, v. 136, n. 1, p. 1, doi. 10.1111/bcpt.14120

By:

Anderson, Lyndsey L.;
Hawkins, Nicole A.;
Yip, Ka Lai;
Udoh, Michael;
Kearney, Jennifer A.;
Arnold, Jonathon C.

Publication type:

Article

Screening of conventional anticonvulsants in a genetic mouse model of epilepsy.

Published in:

Annals of Clinical & Translational Neurology, 2017, v. 4, n. 5, p. 326, doi. 10.1002/acn3.413

By:

Hawkins, Nicole A.;
Anderson, Lyndsey L.;
Gertler, Tracy S.;
Laux, Linda;
George, Alfred L.;
Kearney, Jennifer A.

Publication type:

Article

Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 17, p. 2964, doi. 10.1093/hmg/ddac087

By:

Echevarria-Cooper, Dennis M;
Hawkins, Nicole A;
Misra, Sunita N;
Huffman, Alexandra M;
Thaxton, Tyler;
Thompson, Christopher H;
Ben-Shalom, Roy;
Nelson, Andrew D;
Lipkin, Anna M;
Jr, Alfred L George;
Bender, Kevin J;
Kearney, Jennifer A

Publication type:

Article

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36087-x

By:

Forrest, Marc P.;
Dos Santos, Marc;
Piguel, Nicolas H.;
Wang, Yi-Zhi;
Hawkins, Nicole A.;
Bagchi, Vikram A.;
Dionisio, Leonardo E.;
Yoon, Sehyoun;
Simkin, Dina;
Martin-de-Saavedra, Maria Dolores;
Gao, Ruoqi;
Horan, Katherine E.;
George Jr., Alfred L.;
LeDoux, Mark S.;
Kearney, Jennifer A.;
Savas, Jeffrey N.;
Penzes, Peter

Publication type:

Article

Elevating Black fathers' experiences in the National Fatherhood Initiative: Strengths and areas for improvement of 24/7 Dad® curriculum and case management services.

Published in:

Family Process, 2024, v. 63, n. 4, p. 1926, doi. 10.1111/famp.13036

By:

Voith, Laura A.;
Russell, Katie N.;
Withrow, Ashley;
Kearney, Jennifer;
Xia, Tian;
Coleman, Darrell

Publication type:

Article

De novo KCNB1 mutations in epileptic encephalopathy.

Published in:

Annals of Neurology, 2014, v. 76, n. 4, p. 529, doi. 10.1002/ana.24263

By:

Torkamani, Ali;
Bersell, Kevin;
Jorge, Benjamin S.;
Bjork, Robert L.;
Friedman, Jennifer R.;
Bloss, Cinnamon S.;
Cohen, Julie;
Gupta, Siddharth;
Naidu, Sakkubai;
Vanoye, Carlos G.;
George, Alfred L.;
Kearney, Jennifer A.

Publication type:

Article

Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq.

Published in:

PLoS Genetics, 2016, v. 12, n. 10, p. 1, doi. 10.1371/journal.pgen.1006398

By:

Hawkins, Nicole A.;
Zachwieja, Nicole J.;
Miller, Alison R.;
Anderson, Lyndsey L.;
Kearney, Jennifer A.

Publication type:

Article

Sodium channel mutations in epilepsy and other neurological disorders.

Published in:

2005

By:

Meisler, Miriam H.;
Kearney, Jennifer A.

Publication type:

journal article

Naked Concrete: Mixed-use building features a 16-story exposed concrete exoskeleton.

Published in:

2018

By:

Kearney, Jennifer;
Kates, Zachary;
Tamaro, Mark J.

Publication type:

Architecture Review

4225 Evaluation of Neurotransmitters in Channelopathy-Related Epilepsy.

Published in:

2020

By:

Misra, Sunita N;
Czech, Theresa M.;
Kearney, Jennifer A.

Publication type:

Abstract

Severe epilepsy resulting from genetic interaction between Scn2a and Kcnq2.

Published in:

Human Molecular Genetics, 2006, v. 15, n. 6, p. 1043, doi. 10.1093/hmg/ddl019

By:

Kearney, Jennifer A.;
Yang, Yan;
Beyer, Barbara;
Bergren, Sarah K.;
Claes, Lieve;
DeJonghe, Peter;
Frankel, Wayne N.

Publication type:

Article

Sacred disease secrets revealed: the genetics of human epilepsy.

Published in:

Human Molecular Genetics, 2005, v. 14, n. 17, p. 2491, doi. 10.1093/hmg/ddi250

By:

Turnbull, Julie;
Lohi, Hannes;
Kearney, Jennifer A.;
Rouleau, Guy A.;
Delgado-Escueta, Antonio V.;
Meisler, Miriam H.;
Cossette, Patrick;
Minassian, Berge A.

Publication type:

Article

Molecular and pathological effects of a modifier gene on deficiency of the sodium channel Scn8a (Nav1.6).

Published in:

Human Molecular Genetics, 2002, v. 11, n. 22, p. 2765, doi. 10.1093/hmg/11.22.2765

By:

Kearney, Jennifer A.;
Buchner, David A.;
de Haan, Georgius;
Adamska, Maja;
Levin, Stephen I.;
Furay, Amy R.;
Albin, Roger L.;
Jones, Julie M.;
Montal, Mauricio;
Stevens, Martin J.;
Sprunger, Leslie K.;
Meisler, Miriam H.

Publication type:

Article

C57BL/6J and C57BL/6N substrains differentially influence phenotype severity in the Scn1a+/− mouse model of Dravet syndrome.

Published in:

Epilepsia Open, 2019, v. 4, n. 1, p. 164, doi. 10.1002/epi4.12287

By:

Kang, Seok K.;
Hawkins, Nicole A.;
Kearney, Jennifer A.

Publication type:

Article

Enhanced Synaptic Transmission in the Extended Amygdala and Altered Excitability in an Extended Amygdala to Brainstem Circuit in a Dravet Syndrome Mouse Model.

Published in:

eNeuro, 2021, v. 8, n. 3, p. 1, doi. 10.1523/ENEURO.0306-20.2021

By:

Wen Wei Yan;
Maya Xia;
Jeremy Chiang;
Levitt, Alyssa;
Hawkins, Nicole;
Kearney, Jennifer;
Swanson, Geoffrey T.;
Chetkovich, Dane;
Nobis, William P.

Publication type:

Article

Potentiating α2 subunit containing perisomatic GABAA receptors protects against seizures in a mouse model of Dravet syndrome.

Published in:

Journal of Physiology, 2019, v. 597, n. 16, p. 4293, doi. 10.1113/JP277651

By:

Nomura, Toshihiro;
Hawkins, Nicole A.;
Kearney, Jennifer A.;
George, Alfred L.;
Contractor, Anis

Publication type:

Article

The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the Scn1a +/− Mouse Model of Dravet Syndrome.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.675128

By:

Satpute Janve, Vaishali;
Anderson, Lyndsey L.;
Bahceci, Dilara;
Hawkins, Nicole A.;
Kearney, Jennifer A.;
Arnold, Jonathon C.

Publication type:

Article

Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a+/- mouse model of Dravet syndrome.

Published in:

PLoS ONE, 2023, v. 18, n. 1, p. 1, doi. 10.1371/journal.pone.0280842

By:

Anderson, Lyndsey L.;
Bahceci, Dilara A.;
Hawkins, Nicole A.;
Everett-Morgan, Declan;
Banister, Samuel D.;
Kearney, Jennifer A.;
Arnold, Jonathon C.

Publication type:

Article

Fine mapping and candidate gene analysis of Dravet syndrome modifier loci on mouse chromosomes 7 and 8.

Published in:

Mammalian Genome, 2024, v. 35, n. 3, p. 334, doi. 10.1007/s00335-024-10046-3

By:

Hawkins, Nicole A.;
Speakes, Nathan;
Kearney, Jennifer A.

Publication type:

Article

Fine mapping and candidate gene analysis of a dravet syndrome modifier locus on mouse chromosome 11.

Published in:

Mammalian Genome, 2022, v. 33, n. 4, p. 565, doi. 10.1007/s00335-022-09955-y

By:

Kearney, Jennifer A.;
Copeland-Hardin, Letonia D.;
Duarte, Samantha;
Zachwieja, Nicole A.;
Eckart-Frank, Isaiah K.;
Hawkins, Nicole A.

Publication type:

Article

Gabra2 is a genetic modifier of Dravet syndrome in mice.

Published in:

Mammalian Genome, 2021, v. 32, n. 5, p. 350, doi. 10.1007/s00335-021-09877-1

By:

Hawkins, Nicole A.;
Nomura, Toshihiro;
Duarte, Samantha;
Barse, Levi;
Williams, Robert W.;
Homanics, Gregg E.;
Mulligan, Megan K.;
Contractor, Anis;
Kearney, Jennifer A.

Publication type:

Article

Fine mapping of an epilepsy modifier gene on mouse Chromosome 19.

Published in:

Mammalian Genome, 2009, v. 20, n. 6, p. 359, doi. 10.1007/s00335-009-9193-6

By:

Bergren, Sarah K.;
Rutter, Elizabeth D.;
Kearney, Jennifer A.

Publication type:

Article

Genetic modifiers affecting severity of epilepsy caused by mutation of sodium channel Scn2a.

Published in:

Mammalian Genome, 2005, v. 16, n. 9, p. 683, doi. 10.1007/s00335-005-0049-4

By:

Bergren, Sarah K.;
Chen, Shu;
Galecki, Andrzej;
Kearney, Jennifer

Publication type:

Article

Cannabigerolic acid, a major biosynthetic precursor molecule in cannabis, exhibits divergent effects on seizures in mouse models of epilepsy.

Published in:

British Journal of Pharmacology, 2021, v. 178, n. 24, p. 4826, doi. 10.1111/bph.15661

By:

Anderson, Lyndsey L.;
Heblinski, Marika;
Absalom, Nathan L.;
Hawkins, Nicole A.;
Bowen, Michael T.;
Benson, Melissa J.;
Zhang, Fan;
Bahceci, Dilara;
Doohan, Peter T.;
Chebib, Mary;
McGregor, Iain S.;
Kearney, Jennifer A.;
Arnold, Jonathon C.

Publication type:

Article

Neurobiology of Disease A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 36, p. 7912, doi. 10.1523/JNEUROSCI.0193-18.2018

By:

Favero, Morgana;
Sotuyo, Nathaniel P.;
Lopez, Emily;
Kearney, Jennifer A.;
Goldberg, Ethan M.

Publication type:

Article

Creation of Experience-based Celiac Benchmarks: The First Step in Pretransition Self-management Assessment.

Published in:

2018

By:

Fishman, Laurie N.;
Kearney, Jennifer;
DeGroote, Maya;
Enju Liu;
Arnold, Janis;
Weir, Dascha C.;
Liu, Enju

Publication type:

journal article

Soticlestat, a novel cholesterol 24‐hydroxylase inhibitor, reduces seizures and premature death in Dravet syndrome mice.

Published in:

Epilepsia (Series 4), 2021, v. 62, n. 11, p. 2845, doi. 10.1111/epi.17062

By:

Hawkins, Nicole A.;
Jurado, Manuel;
Thaxton, Tyler T.;
Duarte, Samantha E.;
Barse, Levi;
Tatsukawa, Tetsuya;
Yamakawa, Kazuhiro;
Nishi, Toshiya;
Kondo, Shinichi;
Miyamoto, Maki;
Abrahams, Brett S.;
During, Matthew J.;
Kearney, Jennifer A.

Publication type:

Article

The novel sodium channel modulator GS‐458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy.

Published in:

Epilepsia (Series 4), 2018, v. 59, n. 6, p. 1166, doi. 10.1111/epi.14196

By:

Baker, Erin M.;
Thompson, Christopher H.;
Hawkins, Nicole A.;
George, Jr., Alfred L.;
Kearney, Jennifer A.;
Wagnon, Jacy L.;
Meisler, Miriam H.;
Wengert, Eric R.;
Patel, Manoj K.

Publication type:

Article

Cacna1g is a genetic modifier of epilepsy in a mouse model of Dravet syndrome.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 8, p. e111, doi. 10.1111/epi.13811

By:

Calhoun, Jeffrey D.;
Hawkins, Nicole A.;
Zachwieja, Nicole J.;
Kearney, Jennifer A.

Publication type:

Article

Cacna1g is a genetic modifier of epilepsy caused by mutation of voltage-gated sodium channel Scn2a.

Published in:

Epilepsia (Series 4), 2016, v. 57, n. 6, p. e103, doi. 10.1111/epi.13390

By:

Calhoun, Jeffrey D.;
Hawkins, Nicole A.;
Zachwieja, Nicole J.;
Kearney, Jennifer A.

Publication type:

Article

Antiepileptic activity of preferential inhibitors of persistent sodium current.

Published in:

Epilepsia (Series 4), 2014, v. 55, n. 8, p. 1274, doi. 10.1111/epi.12657

By:

Anderson, Lyndsey L.;
Thompson, Christopher H.;
Hawkins, Nicole A.;
Nath, Ravi D.;
Petersohn, Adam A.;
Rajamani, Sridharan;
Bush, William S.;
Frankel, Wayne N.;
Vanoye, Carlos G.;
Kearney, Jennifer A.;
George, Alfred L.

Publication type:

Article

Epilepsy Benchmarks Area IV: Limit or Prevent Adverse Consequence of Seizures and Their Treatment Across the Life Span.

Published in:

Epilepsy Currents, 2020, v. 20, p. 31S, doi. 10.1177/1535759719895277

By:

Jones, Jana E.;
Asato, Miya R.;
Brown, Mesha-Gay;
Doss, Julia L.;
Felton, Elizabeth A.;
Kearney, Jennifer A.;
Talos, Delia;
Dacks, Penny A.;
Whittemore, Vicky;
Poduri, Annapurna

Publication type:

Article

Alphabet Soup: Recurrent De Novo Mutations in Novel Genes Causing Developmental and Epileptic Encephalopathies.

Published in:

Epilepsy Currents, 2018, v. 18, n. 2, p. 125, doi. 10.5698/1535-7597.18.2.125

By:

Misra, Sunita N.;
Kearney, Jennifer A.

Publication type:

Article

Expanding the Zebrafish Toolkit for Epilepsy Research.

Published in:

Epilepsy Currents, 2018, v. 18, n. 1, p. 56, doi. 10.5698/1535-7597.18.1.56

By:

Kearney, Jennifer A.

Publication type:

Article

A Look Behind the Curtain: Epilepsy Microarray Consortium.

Published in:

Epilepsy Currents, 2017, v. 17, n. 6, p. 374, doi. 10.5698/1535-7597.17.6.374

By:

Kearney, Jennifer A.

Publication type:

Article

The Big Picture: Systems Biology Approach to Antiepileptic Drug Discovery.

Published in:

Epilepsy Currents, 2017, v. 17, n. 4, p. 232, doi. 10.5698/1535-7597.17.4.232

By:

Kearney, Jennifer A.

Publication type:

Article

Precision Medicine: NMDA Receptor-Targeted Therapy for GRIN2D Encephalopathy.

Published in:

Epilepsy Currents, 2017, v. 17, n. 2, p. 112, doi. 10.5698/1535-7511.17.2.112

By:

Kearney, Jennifer A.

Publication type:

Article

Sodium Channel β Subunits in Epilepsy: Location, Location, Location.

Published in:

Epilepsy Currents, 2017, v. 17, n. 1, p. 52, doi. 10.5698/1535-7511-17.1.52

By:

Kearney, Jennifer A.

Publication type:

Article

When Inhibiting Repetitive Firing is Pro-Epileptic.

Published in:

Epilepsy Currents, 2016, v. 16, n. 2, p. 114, doi. 10.5698/1535-7511-16.2.114

By:

Kearney, Jennifer A.

Publication type:

Article

Locus Heterogeneity in Epilepsy of Infancy with Migrating Focal Seizures.

Published in:

Epilepsy Currents, 2016, v. 16, n. 1, p. 43, doi. 10.5698/1535-7597-16.1.43

By:

Kearney, Jennifer A.

Publication type:

Article

Watch Out, No Brakes! Impaired Inhibition Results in Hyperexcitable Networks.

Published in:

Epilepsy Currents, 2015, v. 15, n. 6, p. 342, doi. 10.5698/1535-7511-15.6.342

By:

Thompson, Christopher H.;
Kearney, Jennifer A.

Publication type:

Article

Synaptopathies Heat Up: Mutations in STX1B in Fever-Associated Epilepsies.

Published in:

Epilepsy Currents, 2015, v. 15, n. 3, p. 138, doi. 10.5698/1535-7597-15.3.138

By:

Kearney, Jennifer A.

Publication type:

Article

TALE of an SCN8A-Associated Epileptic Encephalopathy Mouse Model.

Published in:

Epilepsy Currents, 2015, v. 15, n. 2, p. 83, doi. 10.5698/1535-7597-15.2.83

By:

Kearney, Jennifer A.

Publication type:

Article

Double Trouble: Impairment of Two Interneuron Types in a Dravet Mouse Model.

Published in:

Epilepsy Currents, 2015, v. 15, n. 1, p. 47, doi. 10.5698/1535-7597-15.1.47

By:

Kearney, Jennifer A.

Publication type:

Article

Epi4K Phase I: Gene Discovery in Epileptic Encephalopathies by Exome Sequencing.

Published in:

Epilepsy Currents, 2014, v. 14, n. 4, p. 208, doi. 10.5698/1535-7597-14.4.208

By:

Kearney, Jennifer A.

Publication type:

Article

The More, the Better: Modeling Dravet Syndrome With Induced Pluripotent Stem Cell-Derived Neurons.

Published in:

Epilepsy Currents, 2014, v. 14, n. 1, p. 33, doi. 10.5698/1535-7597-14.1.33

By:

Kearney, Jennifer

Publication type:

Article

Sudden Unexpected Death in Dravet Syndrome.

Published in:

Epilepsy Currents, 2013, v. 13, n. 6, p. 264, doi. 10.5698/1535-7597-13.6.264

By:

Kearney, Jennifer

Publication type:

Article

Less is More: Reducing Tau Ameliorates Seizures in Epilepsy Models.

Published in:

Epilepsy Currents, 2013, v. 13, n. 4, p. 184, doi. 10.5698/1535-7597-13.4.184

By:

Kearney, Jennifer A.

Publication type:

Article

Cognitive and Social Impairment in Mouse Models Mirrors Dravet Syndrome.

Published in:

Epilepsy Currents, 2013, v. 13, n. 2, p. 97, doi. 10.5698/1535-7597-13.2.97

By:

Kearney, Jennifer A.

Publication type:

Article