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Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next‐generation human artificial chromosomes for Duchenne muscular dystrophy.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 2, p. 254, doi. 10.15252/emmm.201607284
By:
- Benedetti, Sara;
- Uno, Narumi;
- Hoshiya, Hidetoshi;
- Ragazzi, Martina;
- Ferrari, Giulia;
- Kazuki, Yasuhiro;
- Moyle, Louise Anne;
- Tonlorenzi, Rossana;
- Lombardo, Angelo;
- Chaouch, Soraya;
- Mouly, Vincent;
- Moore, Marc;
- Popplewell, Linda;
- Kazuki, Kanako;
- Katoh, Motonobu;
- Naldini, Luigi;
- Dickson, George;
- Messina, Graziella;
- Oshimura, Mitsuo;
- Cossu, Giulio
Publication type:
Article
Exogenous gene expression and growth regulation of hematopoietic cells via a novel human artificial chromosome.
Published in:
Journal of Human Genetics, 2006, v. 51, n. 2, p. 147, doi. 10.1007/s10038-005-0334-9
By:
- Yamada, Hidetoshi;
- Kunisato, Atsushi;
- Kawahara, Masahiro;
- Tahimic, Candice G. T.;
- Xianying Ren;
- Ueda, Hiroshi;
- Nagamune, Teruyuki;
- Katoh, Motonobu;
- Inoue, Toshiaki;
- Nishikawa, Mitsuo;
- Oshimura, Mitsuo
Publication type:
Article
A novel expression system for genomic DNA loci using a human artificial chromosome vector with transformation-associated recombination cloning.
Published in:
Journal of Human Genetics, 2005, v. 50, n. 11, p. 592, doi. 10.1007/s10038-005-0300-6
By:
- Ayabe, Fumiaki;
- Katoh, Motonobu;
- Inoue, Toshiaki;
- Kouprina, Natalay;
- Larionov, Vladimir;
- Oshimura, Mitsuo
Publication type:
Article
A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges.
Published in:
Chromosome Research, 2015, v. 23, n. 1, p. 111, doi. 10.1007/s10577-014-9459-z
By:
- Oshimura, Mitsuo;
- Uno, Narumi;
- Kazuki, Yasuhiro;
- Katoh, Motonobu;
- Inoue, Toshiaki
Publication type:
Article
Integration-Free iPS Cells Engineered Using Human Artificial Chromosome Vectors.
Published in:
PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0025961
By:
- Hiratsuka, Masaharu;
- Uno, Narumi;
- Ueda, Kana;
- Kurosaki, Hajime;
- Imaoka, Natsuko;
- Kazuki, Kanako;
- Ueno, Etsuya;
- Akakura, Yutaro;
- Katoh, Motonobu;
- Osaki, Mitsuhiko;
- Kazuki, Yasuhiro;
- Nakagawa, Masato;
- Yamanaka, Shinya;
- Oshimura, Mitsuo
Publication type:
Article
SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis.
Published in:
Genes to Cells, 2011, v. 16, n. 1, p. 34, doi. 10.1111/j.1365-2443.2010.01460.x
By:
- Li, Yanze;
- Matsumori, Haruka;
- Nakayama, Yuji;
- Osaki, Mitsuhiko;
- Kojima, Hirotada;
- Kurimasa, Akihiro;
- Ito, Hisao;
- Mori, Seiichi;
- Katoh, Motonobu;
- Oshimura, Mitsuo;
- Inoue, Toshiaki
Publication type:
Article
Identification of a ≦600-kb region on human chromosome 1q42.3 inducing cellular senescence.
Published in:
Oncogene, 2003, v. 22, n. 2, p. 281, doi. 10.1038/sj.onc.1206143
By:
- Yawata, Toshio;
- Kamino, Hiroki;
- Kugoh, Hiroyuki;
- Katoh, Motonobu;
- Nomura, Nobuo;
- Oishi, Michio;
- Horikawa, Izumi;
- Barrett, J Carl;
- Oshimura, Mitsuo
Publication type:
Article
SIRT2 knockdown increases basal autophagy and prevents postslippage death by abnormally prolonging the mitotic arrest that is induced by microtubule inhibitors.
Published in:
FEBS Journal, 2014, v. 281, n. 11, p. 2623, doi. 10.1111/febs.12810
By:
- Inoue, Toshiaki;
- Nakayama, Yuji;
- Li, Yanze;
- Matsumori, Haruka;
- Takahashi, Haruka;
- Kojima, Hirotada;
- Wanibuchi, Hideki;
- Katoh, Motonobu;
- Oshimura, Mitsuo
Publication type:
Article
Telomerase activity correlates with histo-pathological factors in uterine endometrial carcinoma.
Published in:
International Journal of Cancer, 1999, v. 84, n. 5, p. 529, doi. 10.1002/(SICI)1097-0215(19991022)84:5<529::AID-IJC15>3.0.CO;2-J
By:
- Ebina, Yasuhiko;
- Yamada, Hideto;
- Fujino, Takafumi;
- Furuta, Itsuko;
- Sakuragi, Noriaki;
- Yamamoto, Ritsu;
- Katoh, Motonobu;
- Oshimura, Mitsuo;
- Fujimoto, Seiichiro
Publication type:
Article
Frequent loss of imprinting of IGF2 and MEST in lung adenocarcinoma.
Published in:
Molecular Carcinogenesis, 2001, v. 31, n. 4, p. 184, doi. 10.1002/mc.1053
By:
- Kohda, Masakazu;
- Hoshiya, Hidetoshi;
- Katoh, Motonobu;
- Tanaka, Isao;
- Masuda, Ryo;
- Takemura, Tamiko;
- Fujiwara, Mutsunori;
- Oshimura, Mitsuo
Publication type:
Article
A repressor function for telomerase activity in telomerase-negative immortal cells.
Published in:
Molecular Carcinogenesis, 1998, v. 21, n. 1, p. 17, doi. 10.1002/(SICI)1098-2744(199801)21:1<17::AID-MC4>3.0.CO;2-M
By:
- Katoh, Motonobu;
- Katoh, Misaki;
- Kameyama, Michihiro;
- Kugoh, Hiroyuki;
- Shimizu, Motoyuki;
- Oshimura, Mitsuo
Publication type:
Article
Transfer of human artificial chromosome vectors into stem cells.
Published in:
Reproductive BioMedicine Online (Reproductive Healthcare Limited), 2008, v. 16, n. 1, p. 57, doi. 10.1016/S1472-6483(10)60557-3
By:
- Oshimura, Mitsuo;
- Katoh, Motonobu
Publication type:
Article
742. Human Artificial Chromosome (HAC) Vector Provides Long-Term Therapeutic Transgene Expression in Normal Human Primary Fibroblasts
Published in:
2005
By:
- Kakeda, Minoru;
- Hiratsuka, Masaharu;
- Nagata, Keiko;
- Sano, Akiko;
- Osawa, Kanako;
- Katoh, Motonobu;
- Oshimura, Mitsuo;
- Tomizuka, Kazuma
Publication type:
Abstract
Retargeting of microcell fusion towards recipient cell-oriented transfer of human artificial chromosome.
Published in:
BMC Biotechnology, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12896-015-0142-z
By:
- Masaharu Hiratsuka;
- Kana Ueda;
- Narumi Uno;
- Katsuhiro Uno;
- Sayaka Fukuhara;
- Hajime Kurosaki;
- Shoko Takehara;
- Mitsuhiko Osaki;
- Yasuhiro Kazuki;
- Yoshikazu Kurosawa;
- Takafumi Nakamura;
- Motonobu Katoh;
- Mitsuo Oshimura
Publication type:
Article
Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells formicrocell-mediated chromosome transfer.
Published in:
BMC Biotechnology, 2010, v. 10, p. 37, doi. 10.1186/1472-6750-10-37
By:
- Katoh, Motonobu;
- Kazuki, Yasuhiro;
- Kazuki, Kanako;
- Kajitani, Naoyo;
- Takiguchi, Masato;
- Nakayama, Yuji;
- Nakamura, Takafumi;
- Oshimura, Mitsuo
Publication type:
Article
Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down’s syndrome.
Published in:
Human Molecular Genetics, 2001, v. 10, n. 11, p. 1163, doi. 10.1093/hmg/10.11.1163
By:
- Shinohara, Tokuyuki;
- Tomizuka, Kazuma;
- Miyabara, Shinichi;
- Takehara, Shoko;
- Kazuki, Yasuhiro;
- Inoue, Jun;
- Katoh, Motonobu;
- Nakane, Hironobu;
- Iino, Akihiro;
- Ohguma, Atsuko;
- Ikegami, Shiro;
- Inokuchi, Kaoru;
- Ishida, Isao;
- Reeves, Roger H.;
- Oshimura, Mitsuo
Publication type:
Article
Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome.
Published in:
Human Molecular Genetics, 2001, v. 10, n. 11, p. 1163, doi. 10.1093/hmg/10.11.1163
By:
- Shinohara, Tokuyuki;
- Tomizuka, Kazuma;
- Miyabara, Shinichi;
- Takehara, Shoko;
- Kazuki, Yasuhiro;
- Inoue, Jun;
- Katoh, Motonobu;
- Nakane, Hironobu;
- Iino, Akihiro;
- Ohguma, Atsuko;
- Ikegami, Shiro;
- Inokuchi, Kaoru;
- Ishida, Isao;
- Reeves, Roger H.;
- Oshimura, Mitsuo
Publication type:
Article
LIT1, an imprinted antisense RNA in the human KvLQT1 locus indentified by screening for differntially expressed transcripts using monochromosomal hybrids.
Published in:
Human Molecular Genetics, 1999, v. 8, n. 7, p. 1209, doi. 10.1093/hmg/8.7.1209
By:
- Mitsuya, Kohzoh;
- Meguro, Makiko;
- Lee, Maxwell P.;
- Katoh, Motonobu;
- Schulz, Thomas C.;
- Kugoh, Hiroyuki;
- Yoshida, Mitsuaki A.;
- Niikawa, Norio;
- Feinberg, Andrew P.;
- Oshimura, Mitsuo
Publication type:
Article

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