Found: 8

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  • TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions.

    Published in:
    eLife, 2016, p. 1, doi. 10.7554/eLife.17929
    By:
    • Shirole, Nitin H.;
    • Pal, Debjani;
    • Kastenhuber, Edward R.;
    • Senturk, Serif;
    • Boroda, Joseph;
    • Pisterzi, Paola;
    • Miller, Madison;
    • Munoz, Gustavo;
    • Anderluh, Marko;
    • Ladanyi, Marc;
    • Lowe, Scott W.;
    • Sordella, Raffaella
    Publication type:
    Article

  • Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

    Published in:
    Nature Biotechnology, 2022, v. 40, n. 6, p. 862, doi. 10.1038/s41587-021-01172-3
    By:
    • Sánchez-Rivera, Francisco J.;
    • Diaz, Bianca J.;
    • Kastenhuber, Edward R.;
    • Schmidt, Henri;
    • Katti, Alyna;
    • Kennedy, Margaret;
    • Tem, Vincent;
    • Ho, Yu-Jui;
    • Leibold, Josef;
    • Paffenholz, Stella V.;
    • Barriga, Francisco M.;
    • Chu, Kevan;
    • Goswami, Sukanya;
    • Wuest, Alexandra N.;
    • Simon, Janelle M.;
    • Tsanov, Kaloyan M.;
    • Chakravarty, Debyani;
    • Zhang, Hongxin;
    • Leslie, Christina S.;
    • Lowe, Scott W.
    Publication type:
    Article

  • Optimized base editors enable efficient editing in cells, organoids and mice.

    Published in:
    Nature Biotechnology, 2018, v. 36, n. 10, p. 888, doi. 10.1038/nbt.4194
    By:
    • Zafra, Maria Paz;
    • Schatoff, Emma M;
    • Katti, Alyna;
    • Foronda, Miguel;
    • Breinig, Marco;
    • Schweitzer, Anabel Y;
    • Simon, Amber;
    • Han, Teng;
    • Goswami, Sukanya;
    • Montgomery, Emma;
    • Thibado, Jordana;
    • Kastenhuber, Edward R;
    • Sánchez-Rivera, Francisco J;
    • Shi, Junwei;
    • Vakoc, Christopher R;
    • Lowe, Scott W;
    • Tschaharganeh, Darjus F;
    • Dow, Lukas E
    Publication type:
    Article

  • Optimized base editors enable efficient editing in cells, organoids and mice.

    Published in:
    Nature Biotechnology, 2018, v. 36, n. 9, p. 888, doi. 10.1038/nbt.4194
    By:
    • Zafra, Maria Paz;
    • Schatoff, Emma M;
    • Katti, Alyna;
    • Foronda, Miguel;
    • Breinig, Marco;
    • Schweitzer, Anabel Y;
    • Simon, Amber;
    • Han, Teng;
    • Goswami, Sukanya;
    • Montgomery, Emma;
    • Thibado, Jordana;
    • Kastenhuber, Edward R;
    • Sánchez-Rivera, Francisco J;
    • Shi, Junwei;
    • Vakoc, Christopher R;
    • Lowe, Scott W;
    • Tschaharganeh, Darjus F;
    • Dow, Lukas E
    Publication type:
    Article

  • Inducible in vivo genome editing with CRISPR-Cas9.

    Published in:
    Nature Biotechnology, 2015, v. 33, n. 4, p. 390, doi. 10.1038/nbt.3155
    By:
    • Dow, Lukas E;
    • Fisher, Jonathan;
    • O'Rourke, Kevin P;
    • Muley, Ashlesha;
    • Kastenhuber, Edward R;
    • Livshits, Geulah;
    • Tschaharganeh, Darjus F;
    • Socci, Nicholas D;
    • Lowe, Scott W
    Publication type:
    Article

  • Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-α and IFN-γ dependent manners.

    Published in:
    Cancer Immunology, Immunotherapy, 2010, v. 59, n. 9, p. 1401, doi. 10.1007/s00262-010-0876-3
    By:
    • Xinmei Zhu;
    • Fallert-Junecko, Beth A.;
    • Mitsugu Fujita;
    • Ryo Ueda;
    • Kohanbash, Gary;
    • Kastenhuber, Edward R.;
    • McDonald, Heather A.;
    • Yan Liu;
    • Kalinski, Pawel;
    • Reinhart, Todd A.;
    • Salazar, Andres M.;
    • Hideho Okada
    Publication type:
    Article

  • Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry.

    Published in:
    eLife, 2022, p. 1, doi. 10.7554/eLife.77444
    By:
    • Kastenhuber, Edward R.;
    • Mercadante, Marisa;
    • Nilsson-Payant, Benjamin;
    • Johnson, Jared L.;
    • Jaimes, Javier A.;
    • Muecksch, Frauke;
    • Weisblum, Yiska;
    • Bram, Yaron;
    • Chandar, Vasuretha;
    • Whittaker, Gary R.;
    • tenOever, Benjamin R.;
    • Schwartz, Robert E.;
    • Cantley, Lewis
    Publication type:
    Article

  • Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.

    Published in:
    Science Signaling, 2022, v. 15, n. 757, p. 1, doi. 10.1126/scisignal.abm0808
    By:
    • Yaron, Tomer M.;
    • Heaton, Brook E.;
    • Levy, Tyler M.;
    • Johnson, Jared L.;
    • Jordan, Tristan X.;
    • Cohen, Benjamin M.;
    • Kerelsky, Alexander;
    • Lin, Ting-Yu;
    • Liberatore, Katarina M.;
    • Bulaon, Danielle K.;
    • Van Nest, Samantha J.;
    • Koundouros, Nikos;
    • Kastenhuber, Edward R.;
    • Mercadante, Marisa N.;
    • Shobana-Ganesh, Kripa;
    • He, Long;
    • Schwartz, Robert E.;
    • Chen, Shuibing;
    • Weinstein, Harel;
    • Elemento, Olivier
    Publication type:
    Article