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Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch.
Published in:
Journal of Pathology, 2017, v. 243, n. 1, p. 37, doi. 10.1002/path.4923
By:
- Tod, Jo;
- Hanley, Christopher J;
- Morgan, Mark R;
- Rucka, Marta;
- Mellows, Toby;
- Lopez, Maria‐Antoinette;
- Kiely, Philip;
- Moutasim, Karwan A;
- Frampton, Steven J;
- Sabnis, Durgagauri;
- Fine, David R;
- Johnson, Colin;
- Marshall, John F;
- Scita, Giorgio;
- Jenei, Veronika;
- Thomas, Gareth J
Publication type:
Article
Suppression of Hedgehog signalling promotes pro-tumourigenic integrin expression and function.
Published in:
Journal of Pathology, 2014, v. 233, n. 2, p. 196, doi. 10.1002/path.4342
By:
- Moutasim, Karwan A;
- Mellows, Toby;
- Mellone, Massimiliano;
- Lopez, Marie‐Antoinette;
- Tod, Joanne;
- Kiely, Philip C;
- Sapienza, Karen;
- Greco, Azzura;
- Neill, Graham W;
- Violette, Shelia;
- Weinreb, Paul H;
- Marshall, John F;
- Ottensmeier, Christian H;
- Sayan, A Emre;
- Jenei, Veronika;
- Thomas, Gareth J
Publication type:
Article
Stromal features are predictive of disease mortality in oral cancer patients.
Published in:
Journal of Pathology, 2011, v. 223, n. 4, p. 470, doi. 10.1002/path.2830
By:
- Marsh, Daniel;
- Suchak, Krishna;
- Moutasim, Karwan A;
- Vallath, Sabarinath;
- Hopper, Colin;
- Jerjes, Waseem;
- Upile, Tahwinder;
- Kalavrezos, Nicholas;
- Violette, Shelia M;
- Weinreb, Paul H;
- Chester, Kerry A;
- Chana, Jagdeep S;
- Marshall, John F;
- Hart, Ian R;
- Hackshaw, Allan K;
- Piper, Kim;
- Thomas, Gareth J
Publication type:
Article
GLI1 Confers Profound Phenotypic Changes upon LNCaP Prostate Cancer Cells That Include the Acquisition of a Hormone Independent State.
Published in:
PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0020271
By:
- Nadendla, Sandeep K.;
- Hazan, Allon;
- Ward, Matt;
- Harper, Lisa J.;
- Moutasim, Karwan;
- Bianchi, Lucia S.;
- Naase, Mahmoud;
- Ghali, Lucy;
- Thomas, Gareth J.;
- Prowse, David M.;
- Philpott, Michael P.;
- Neill1, Graham W.
Publication type:
Article
CTEN Induces Tumour Cell Invasion and Survival and Is Prognostic in Radiotherapy-Treated Head and Neck Cancer.
Published in:
Cancers, 2020, v. 12, n. 10, p. 2963, doi. 10.3390/cancers12102963
By:
- Fleming, Jason C.;
- Woo, Jeongmin;
- Moutasim, Karwan;
- Hanley, Christopher J.;
- Frampton, Steven J.;
- Wood, Oliver;
- Ward, Matthew;
- Woelk, Christopher H.;
- Ottensmeier, Christian H.;
- Hafizi, Sassan;
- Kim, Dae;
- Thomas, Gareth J.
Publication type:
Article
The ZEB2‐dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer.
Published in:
Molecular Oncology, 2021, v. 15, n. 8, p. 2065, doi. 10.1002/1878-0261.12965
By:
- Sreekumar, Rahul;
- Al‐Saihati, Hajir;
- Emaduddin, Muhammad;
- Moutasim, Karwan;
- Mellone, Massimiliano;
- Patel, Ashish;
- Kilic, Seval;
- Cetin, Metin;
- Erdemir, Sule;
- Navio, Marta Salgado;
- Lopez, Maria Antonette;
- Curtis, Nathan;
- Yagci, Tamer;
- Primrose, John N.;
- Price, Brendan D.;
- Berx, Geert;
- Thomas, Gareth J.;
- Tulchinsky, Eugene;
- Mirnezami, Alex;
- Sayan, A. Emre
Publication type:
Article
Intratumoural immune signature to identify patients with primary colorectal cancer who do not require follow-up after resection: an observational study.
Published in:
Health Technology Assessment, 2021, v. 25, n. 2, p. v, doi. 10.3310/hta25020
By:
- Primrose, John N.;
- Pugh, Siân A.;
- Thomas, Gareth;
- Ellis, Matthew;
- Moutasim, Karwan;
- Mant, David
Publication type:
Article
HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma.
Published in:
2019
By:
- Fleming, Jason C.;
- Woo, Jeongmin;
- Moutasim, Karwan;
- Mellone, Massimiliano;
- Frampton, Steven J.;
- Mead, Abbie;
- Ahmed, Waseem;
- Wood, Oliver;
- Robinson, Hollie;
- Ward, Matthew;
- Woelk, Christopher H.;
- Ottensmeier, Christian H.;
- King, Emma;
- Kim, Dae;
- Blaydes, Jeremy P.;
- Thomas, Gareth J.
Publication type:
journal article
Evaluating the effect of immune cells on the outcome of patients with mesothelioma.
Published in:
2017
By:
- Chee, Serena J;
- Lopez, Maria;
- Mellows, Toby;
- Gankande, Sharmali;
- Moutasim, Karwan A;
- Harris, Scott;
- Clarke, James;
- Vijayanand, Pandurangan;
- Thomas, Gareth J;
- Ottensmeier, Christian H
Publication type:
journal article
Crowdsourcing for translational research: analysis of biomarker expression using cancer microarrays.
Published in:
2017
By:
- Lawson, Jonathan;
- Robinson-Vyas, Rupesh J;
- McQuillan, Janette P;
- Paterson, Andy;
- Christie, Sarah;
- Kidza-Griffiths, Matthew;
- McDuffus, Leigh-Anne;
- Moutasim, Karwan A;
- Shaw, Emily C;
- Kiltie, Anne E;
- Howat, William J;
- Hanby, Andrew M;
- Thomas, Gareth J;
- Smittenaar, Peter
Publication type:
journal article
Protein kinase C inhibitors override ZEB1-induced chemoresistance in HCC.
Published in:
Cell Death & Disease, 2019, v. 10, n. 10, p. N.PAG, doi. 10.1038/s41419-019-1885-6
By:
- Sreekumar, Rahul;
- Emaduddin, Muhammad;
- Al-Saihati, Hajir;
- Moutasim, Karwan;
- Chan, James;
- Spampinato, Marcello;
- Bhome, Rahul;
- Yuen, Ho Ming;
- Mescoli, Claudia;
- Vitale, Alessandro;
- Cillo, Umberto;
- Rugge, Massimo;
- Primrose, John;
- Hilal, Mohammad Abu;
- Thirdborough, Stephen;
- Tulchinsky, Eugene;
- Thomas, Gareth;
- Mirnezami, Alex;
- Sayan, A. Emre
Publication type:
Article
A comparison of primary oesophageal squamous epithelial cells with HET-1A in organotypic culture.
Published in:
Biology of the Cell (Wiley-Blackwell), 2010, v. 102, n. 12, p. 635, doi. 10.1042/BC20100071
By:
- Timothy J. Underwood;
- Mathieu F. Derouet;
- Michael J. White;
- Fergus Noble;
- Karwan A. Moutasim;
- Eric Smith;
- Paul A. Drew;
- Gareth J. Thomas;
- John N. Primrose;
- Jeremy P. Blaydes
Publication type:
Article
Breast cancer in patients with germline TP53 pathogenic variants have typical tumour characteristics: the Cohort study of TP53 carrier early onset breast cancer (COPE study).
Published in:
Journal of Pathology: Clinical Research, 2019, v. 5, n. 3, p. 189, doi. 10.1002/cjp2.133
By:
- Packwood, Kate;
- Martland, Guy;
- Sommerlad, Matthew;
- Shaw, Emily;
- Moutasim, Karwan;
- Thomas, Gareth;
- Bateman, Adrian C;
- Jones, Louise;
- Haywood, Linda;
- Evans, D Gareth;
- Birch, Jillian M;
- Alsalmi, Ohud A;
- Henderson, Alex;
- Poplawski, Nicola;
- Eccles, Diana M
Publication type:
Article
Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4.
Published in:
2018
By:
- Hanley, Christopher J.;
- Mellone, Massimiliano;
- Ford, Kirsty;
- Thirdborough, Steve M.;
- Mellows, Toby;
- Frampton, Steven J.;
- Smith, David M.;
- Harden, Elena;
- Szyndralewiez, Cedric;
- Bullock, Marc;
- Noble, Fergus;
- Moutasim, Karwan A.;
- King, Emma V.;
- Vijayanand, Pandurangan;
- Mirnezami, Alex H.;
- Underwood, Timothy J.;
- Ottensmeier, Christian H.;
- Thomas, Gareth J.
Publication type:
journal article

Found: 14