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Biological Variation in Peripheral Inflammation and Oxidative Stress Biomarkers in Individuals with Gaucher Disease.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9189, doi. 10.3390/ijms23169189
By:
- Sahasrabudhe, Siddhee A.;
- Terluk, Marcia R.;
- Rudser, Kyle D.;
- Cloyd, James C.;
- Kartha, Reena V.
Publication type:
Article
Building cross-border collaborations to increase diversity and accelerate rare disease drug development -- meeting report from the inaugural IndoUSrare Annual Conference 2021.
Published in:
Therapeutic Advances in Rare Disease, 2022, v. 3, p. 1, doi. 10.1177/26330040221133124
By:
- Khera, Harvinder Kour;
- Venugopal, Nisha;
- Karur, Ramya T.;
- Mishra, Rakesh;
- Kartha, Reena V.;
- Rajasimha, Harsha K.
Publication type:
Article
Combinatorial Treatment of DNA and Chromatin-Modifying Drugs Cause Cell Death in Human and Canine Osteosarcoma Cell Lines.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0043720
By:
- Thayanithy, Venugopal;
- Park, ChangWon;
- Sarver, Aaron L.;
- Kartha, Reena V.;
- Korpela, Derek M.;
- Graef, Ashley J.;
- Steer, Clifford J.;
- Modiano, Jaime F.;
- Subramanian, Subbaya;
- Cinti, Caterina
Publication type:
Article
The MiRNA Journey from Theory to Practice as a CNS Biomarker.
Published in:
Frontiers in Genetics, 2016, p. 1, doi. 10.3389/fgene.2016.00011
By:
- Stoicea, Nicoleta;
- Du, Amy;
- Lakis, D. Christie;
- Tipton, Courtney;
- Arias-Morales, Carlos E.;
- Bergese, Sergio D.;
- Thayanithy, Venugopal;
- Kartha, Reena V.
Publication type:
Article
Translational and clinical pharmacology considerations in drug repurposing for X‐linked adrenoleukodystrophy—A rare peroxisomal disorder.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 6, p. 2552, doi. 10.1111/bcp.15090
By:
- Tieu, Julianne H.;
- Sahasrabudhe, Siddhee A.;
- Orchard, Paul J.;
- Cloyd, James C.;
- Kartha, Reena V.
Publication type:
Article
A model-based approach to assess the exposure-response relationship of Lorenzo's oil in adrenoleukodystrophy.
Published in:
British Journal of Clinical Pharmacology, 2016, v. 81, n. 6, p. 1058, doi. 10.1111/bcp.12897
By:
- Ahmed, Mariam A.;
- Kartha, Reena V.;
- Brundage, Richard C.;
- Cloyd, James;
- Basu, Cynthia;
- Carlin, Bradley P.;
- Jones, Richard O.;
- Moser, Ann B.;
- Fatemi, Ali;
- Raymond, Gerald V.
Publication type:
Article
Mechanisms of Antioxidant Induction with High-Dose N-Acetylcysteine in Childhood Cerebral Adrenoleukodystrophy.
Published in:
2015
By:
- Kartha, Reena;
- Zhou, Jie;
- Basso, Lisa;
- Schröder, Henning;
- Orchard, Paul;
- Cloyd, James;
- Kartha, Reena V;
- Schröder, Henning;
- Orchard, Paul J
Publication type:
journal article
Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities.
Published in:
2021
By:
- Cheff, Dorian M.;
- Muotri, Alysson R.;
- Stockwell, Brent R.;
- Schmidt, Edward E.;
- Ran, Qitao;
- Kartha, Reena V.;
- Johnson, Simon C.;
- Mittal, Plavi;
- Arnér, Elias S. J.;
- Wigby, Kristen M.;
- Hall, Matthew D.;
- Ramesh, Sanath Kumar
Publication type:
journal article
Intravital microscopy: An innovative approach to track real‐time muscle integrity and pathology in Pompe disease.
Published in:
Clinical & Translational Discovery, 2024, v. 4, n. 4, p. 1, doi. 10.1002/ctd2.322
By:
- Pillai, Nishitha R.;
- Kartha, Reena V.
Publication type:
Article
N-Acetyl-L-cysteine Protects Human Retinal Pigment Epithelial Cells from Oxidative Damage: Implications for Age-Related Macular Degeneration.
Published in:
Oxidative Medicine & Cellular Longevity, 2019, p. 1, doi. 10.1155/2019/5174957
By:
- Terluk, Marcia R.;
- Ebeling, Mara C.;
- Fisher, Cody R.;
- Kapphahn, Rebecca J.;
- Yuan, Ching;
- Kartha, Reena V.;
- Montezuma, Sandra R.;
- Ferrington, Deborah A.
Publication type:
Article
Physiologically‐Based Pharmacokinetic Model Development, Validation, and Application for Prediction of Eliglustat Drug–Drug Interactions.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1254, doi. 10.1002/cpt.2738
By:
- Sahasrabudhe, Siddhee A.;
- Cheng, Shen;
- Al‐Kofahi, Mahmoud;
- Jarnes, Jeanine R.;
- Weinreb, Neal J.;
- Kartha, Reena V.
Publication type:
Article
Neurochemical abnormalities in patients with type 1 Gaucher disease on standard of care therapy.
Published in:
Journal of Inherited Metabolic Disease, 2020, v. 43, n. 3, p. 564, doi. 10.1002/jimd.12182
By:
- Kartha, Reena V.;
- Joers, James;
- Terluk, Marcia R.;
- Travis, Abigail;
- Rudser, Kyle;
- Tuite, Paul J.;
- Weinreb, Neal J.;
- Jarnes, Jeanine R.;
- Cloyd, James C.;
- Öz, Gülin
Publication type:
Article
Molecular Interactions between Gasotransmitters in Patients with Obstructive Sleep Apnea.
Published in:
International Journal of Translational Medicine, 2022, v. 2, n. 3, p. 408, doi. 10.3390/ijtm2030032
By:
- Pusalavidyasagar, Snigdha;
- Hovde, Laurie B.;
- Lee, Jessie;
- Zhang, Lei;
- Abbasi, Adnan;
- Kartha, Reena V.
Publication type:
Article
N-acetylcysteine Pharmacology and Applications in Rare Diseases—Repurposing an Old Antioxidant.
Published in:
Antioxidants, 2023, v. 12, n. 7, p. 1316, doi. 10.3390/antiox12071316
By:
- Sahasrabudhe, Siddhee A.;
- Terluk, Marcia R.;
- Kartha, Reena V.
Publication type:
Article
Orphan drug development: the increasing role of clinical pharmacology.
Published in:
Journal of Pharmacokinetics & Pharmacodynamics, 2019, v. 46, n. 5, p. 395, doi. 10.1007/s10928-019-09646-3
By:
- Ahmed, Mariam A.;
- Okour, Malek;
- Brundage, Richard;
- Kartha, Reena V.
Publication type:
Article
N -Acetylcysteine Reverses the Mitochondrial Dysfunction Induced by Very Long-Chain Fatty Acids in Murine Oligodendrocyte Model of Adrenoleukodystrophy.
Published in:
Biomedicines, 2021, v. 9, n. 12, p. 1826, doi. 10.3390/biomedicines9121826
By:
- Zhou, Jie;
- Terluk, Marcia R.;
- Orchard, Paul J.;
- Cloyd, James C.;
- Kartha, Reena V.
Publication type:
Article
N-acetylcysteine Provides Cytoprotection in Murine Oligodendrocytes through Heme Oxygenase-1 Activity.
Published in:
Biomedicines, 2020, v. 8, n. 8, p. 240, doi. 10.3390/biomedicines8080240
By:
- Zhou, Jie;
- Terluk, Marcia R.;
- Basso, Lisa;
- Mishra, Usha R.;
- Orchard, Paul J.;
- Cloyd, James C.;
- Schröder, Henning;
- Kartha, Reena V.
Publication type:
Article
MicroRNAs as Biomarkers in Cancer.
Published in:
Diagnostics (2075-4418), 2013, v. 3, n. 1, p. 84, doi. 10.3390/diagnostics3010084
By:
- Sundarbose, Kamini;
- Kartha, Reena V.;
- Subramanian, Subbaya
Publication type:
Article
Population Pharmacokinetic Analysis of N‐Acetylcysteine in Pediatric Patients With Inherited Metabolic Disorders Undergoing Hematopoietic Stem Cell Transplant.
Published in:
Journal of Clinical Pharmacology, 2021, v. 61, n. 12, p. 1638, doi. 10.1002/jcph.1943
By:
- Sahasrabudhe, Siddhee A.;
- Kartha, Reena V.;
- Ng, Michelle;
- Basso, Lisa M.;
- Mishra, Usha;
- Cloyd, James C.;
- Orchard, Paul J.;
- Brundage, Richard C.;
- Coles, Lisa D.
Publication type:
Article
Repeated‐Dose Oral N‐Acetylcysteine in Parkinson's Disease: Pharmacokinetics and Effect on Brain Glutathione and Oxidative Stress.
Published in:
Journal of Clinical Pharmacology, 2018, v. 58, n. 2, p. 158, doi. 10.1002/jcph.1008
By:
- Coles, Lisa D.;
- Tuite, Paul J.;
- Öz, Gülin;
- Mishra, Usha R.;
- Kartha, Reena V.;
- Sullivan, Kathleen M.;
- Cloyd, James C.;
- Terpstra, Melissa
Publication type:
Article
Gaucher disease – more than just a rare lipid storage disease.
Published in:
Journal of Molecular Medicine, 2022, v. 100, n. 4, p. 499, doi. 10.1007/s00109-021-02174-z
By:
- Roh, Jaehyeok;
- Subramanian, Subbaya;
- Weinreb, Neal J.;
- Kartha, Reena V.
Publication type:
Article
Effects of yoga on oxidative stress, motor function, and non-motor symptoms in Parkinson's disease: a pilot randomized controlled trial.
Published in:
Pilot & Feasibility Studies, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1186/s40814-018-0355-8
By:
- Cheung, Corjena;
- Bhimani, Rozina;
- Wyman, Jean F.;
- Konczak, Jürgen;
- Zhang, Lei;
- Mishra, Usha;
- Terluk, Marcia;
- Kartha, Reena V.;
- Tuite, Paul
Publication type:
Article

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