Works by Karpen, Gary H.

Results: 39

Solo or doppio: how many CENP-As make a centromeric nucleosome?

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 6, p. 648, doi. 10.1038/nsmb.2602

By:

Dunleavy, Elaine M;
Zhang, Weiguo;
Karpen, Gary H

Publication type:

Article

H3.3 is deposited at centromeres in S phase as a placeholder for newly assembled CENP-A in G<sub>1</sub> phase.

Published in:

Nucleus (1949-1034), 2011, v. 2, n. 2, p. 146, doi. 10.4161/nucl.2.2.15211

By:

Dunleavy, Elaine M.;
Almouzni, Geneviève;
Karpen, Gary H.

Publication type:

Article

Genome-wide analysis reveals a cell cycle--dependent mechanism controlling centromere propagation.

Published in:

Journal of Cell Biology, 2008, v. 183, n. 5, p. 805, doi. 10.1083/jcb.200806038

By:

Erhardt, Sylvia;
Mellone, Barbara G.;
Betts, Craig M.;
Zhang, Weiguo;
Karpen, Gary H.;
Straight, Aaron F.

Publication type:

Article

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin.

Published in:

PLoS Genetics, 2020, v. 16, n. 3, p. 1, doi. 10.1371/journal.pgen.1008673

By:

Lee, Yuh Chwen G.;
Ogiyama, Yuki;
Martins, Nuno M. C.;
Beliveau, Brian J.;
Acevedo, David;
Wu, C.-ting;
Cavalli, Giacomo;
Karpen, Gary H.

Publication type:

Article

Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin.

Published in:

Nature Structural & Molecular Biology, 2004, v. 11, n. 11, p. 1076, doi. 10.1038/nsmb845

By:

Sullivan, Beth A.;
Karpen, Gary H.

Publication type:

Article

Genetics of P-Element Transpositioni Into Drosophila melanogaster Centric Heterochromatin.

Published in:

Genetics, 2003, v. 165, n. 4, p. 2039, doi. 10.1093/genetics/165.4.2039

By:

Konev, Alexander Y.;
Yan, Christopher M.;
Acevedo, David;
Kennedy, Cameron;
Ward, Elaina;
Lim, Arlene;
Tickoo, Sanjay;
Karpen, Gary H.

Publication type:

Article

Efficient Recovery of Centric Heterochromatin P-Element Insertions in Drosophila melanogaster.

Published in:

Genetics, 2002, v. 161, n. 1, p. 217, doi. 10.1093/genetics/161.1.217

By:

Yan, Christopher M.;
Dobie, Kenneth W.;
Le, Hiep D.;
Konev, Alexander Y.;
Karpen, Gary H.

Publication type:

Article

Modifiers of Terminal Deficiency-Associated Position Effect Variegation in Drosophila.

Published in:

Genetics, 2002, v. 160, n. 3, p. 995, doi. 10.1093/genetics/160.3.995

By:

Donaldson, Kathryn M.;
Lui, Amy;
Karpen, Gary H.

Publication type:

Article

Identification of genetic factors that modify motor performance and body weight using Collaborative Cross mice.

Published in:

Scientific Reports, 2015, p. 16247, doi. 10.1038/srep16247

By:

Mao, Jian-Hua;
Langley, Sasha A.;
Huang, Yurong;
Hang, Michael;
Bouchard, Kristofer E.;
Celniker, Susan E.;
Brown, James B.;
Jansson, Janet K.;
Karpen, Gary H.;
Snijders, Antoine M.

Publication type:

Article

Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment.

Published in:

Scientific Reports, 2015, p. 8919, doi. 10.1038/srep08919

By:

Zhang, Pengju;
Lo, Alvin;
Huang, Yurong;
Huang, Ge;
Liang, Guozhou;
Mott, Joni;
Karpen, Gary H.;
Blakely, Eleanor A.;
Bissell, Mina J.;
Barcellos-Hoff, Mary Helen;
Snijders, Antoine M.;
Mao, Jian-Hua

Publication type:

Article

The Cell Cycle Timing of Centromeric Chromatin Assembly in Drosophila Meiosis Is Distinct from Mitosis Yet Requires CAL1 and CENP-C

Published in:

PLoS Biology, 2012, v. 10, n. 12, p. 1, doi. 10.1371/journal.pbio.1001460

By:

Dunleavy, Elaine M.;
Beier, Nicole L.;
Gorgescu, Walter;
Tang, Jonathan;
Costes, Sylvain V.;
Karpen, Gary H.

Publication type:

Article

Epigenetic regulation of centromeric chromatin: old dogs, new tricks?

Published in:

2008

By:

Allshire, Robin C.;
Karpen, Gary H.

Publication type:

journal article

DETERMINING CENTROMERE IDENTITY: CYCLICAL STORIES AND FORKING PATHS.

Published in:

Nature Reviews Genetics, 2001, v. 2, n. 8, p. 584, doi. 10.1038/35084512

By:

Sullivan, Beth A.;
Blower, Michael D.;
Karpen, Gary H.

Publication type:

Article

Exploring the role of CENP-A Ser18 phosphorylation in CIN and Tumorigenesis.

Published in:

Cell Cycle, 2017, v. 16, n. 24, p. 2323, doi. 10.1080/15384101.2017.1387698

By:

Zhang, Weiguo;
Karpen, Gary H.;
Zhang, Qing

Publication type:

Article

DNA double-strand break movement in heterochromatin depends on the histone acetyltransferase dGcn5.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 19, p. 11753, doi. 10.1093/nar/gkae775

By:

Kendek, Apfrida;
Sandron, Arianna;
Lambooij, Jan-Paul;
Colmenares, Serafin U;
Pociunaite, Severina M;
Gooijers, Iris;
de Groot, Lars;
Karpen, Gary H;
Janssen, Aniek

Publication type:

Article

Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy.

Published in:

Nature Communications, 2016, v. 7, n. 8, p. 12619, doi. 10.1038/ncomms12619

By:

Zhang, Weiguo;
Mao, Jian-Hua;
Zhu, Wei;
Jain, Anshu K.;
Liu, Ke;
Brown, James B.;
Karpen, Gary H.

Publication type:

Article

Unlocking the secrets of the genome.

Published in:

Nature, 2009, v. 459, n. 7249, p. 927, doi. 10.1038/459927a

By:

Celniker, Susan E.;
Dillon, Laura A. L.;
Gerstein, Mark B.;
Gunsalus, Kristin C.;
Henikoff, Steven;
Karpen, Gary H.;
Kellis, Manolis;
Lai, Eric C.;
Lieb, Jason D.;
MacAlpine, David M.;
Micklem, Gos;
Piano, Fabio;
Snyder, Michael;
Stein, Lincoln;
White, Kevin P.;
Waterston, Robert H.

Publication type:

Article

The Activation of a Neocentromere in Drosophila Requires Proximity to an Endogenous Centromere.

Published in:

Genetics, 2001, v. 158, n. 4, p. 1615, doi. 10.1093/genetics/158.4.1615

By:

Maggert, Keith A.;
Karpen, Gary H.

Publication type:

Article

Identification of Chromosome Inheritance Modifiers in Drosophila melanogaster.

Published in:

Genetics, 2001, v. 157, n. 4, p. 1623, doi. 10.1093/genetics/157.4.1623

By:

Dobie, Kenneth W.;
Kennedy, Cameron D.;
Velasco, Vivienne M.;
McGrath, Tory L.;
Weko, Juliani;
Patterson, Ryan W.;
Karpen, Gary H.

Publication type:

Article

Trans-suppression of terminal deficiency-associated position effect variegation in a Drosophila...

Published in:

Genetics, 1997, v. 145, n. 2, p. 326, doi. 10.1093/genetics/145.2.325

By:

Donaldson, Kathryn M.;
Karpen, Gary H.

Publication type:

Article

Preferential Transposition of Drosophila P Elements to Nearby Chromosomal Sites.

Published in:

Genetics, 1993, v. 133, n. 2, p. 347

By:

Tower, John;
Karpen, Gary H.;
Craig, Nancy;
Spradling, Allan C.

Publication type:

Article

Analysis of Subtelomeric Heterochromatin in the Drosophila Minichromosome Dp1187 by Single P Element Insertional Mutagenesis.

Published in:

Genetics, 1992, v. 132, n. 3, p. 737

By:

Karpen, Gary H.;
Spradling, Allan C.

Publication type:

Article

Sixty Years of Mystery.

Published in:

Genetics, 1990, v. 126, n. 4, p. 779

By:

Allan C. Spradling, Allan C.;
Karpen, Gary H.

Publication type:

Article

Extensive regulatory capabilities of a Drosophila imaginal disk blastema.

Published in:

Nature, 1981, v. 294, n. 5843, p. 744, doi. 10.1038/294744a0

By:

Karpen, Gary H.;
Schubiger, Gerold

Publication type:

Article

Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.63368

By:

Kasinathan, Bhavatharini;
Colmenares III, Serafin U.;
McConnell, Hannah;
Young, Janet M.;
Karpen, Gary H.;
Malik, Harmit S.

Publication type:

Article

RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.48940

By:

Mills, Wilbur Kyle;
Lee, Yuh Chwen G.;
Kochendoerfer, Antje M.;
Dunleavy, Elaine M.;
Karpen, Gary H.

Publication type:

Article

The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.16096

By:

Swenson, Joel M.;
Colmenares, Serafin U.;
Strom, Amy R.;
Costes, Sylvain V.;
Karpen, Gary H.

Publication type:

Article

Heterochromatic breaks move to the nuclear periphery to continue recombinational repair.

Published in:

Nature Cell Biology, 2015, v. 17, n. 11, p. 1401, doi. 10.1038/ncb3258

By:

Ryu, Taehyun;
Spatola, Brett;
Delabaere, Laetitia;
Bowlin, Katherine;
Hopp, Hannah;
Kunitake, Ryan;
Karpen, Gary H.;
Chiolo, Irene

Publication type:

Article

H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability.

Published in:

Nature Cell Biology, 2007, v. 9, n. 1, p. 25, doi. 10.1038/ncb1514

By:

Peng, Jamy C.;
Karpen, Gary H.

Publication type:

Article

The ABCs of centromeres.

Published in:

Nature Cell Biology, 2006, v. 8, n. 5, p. 427, doi. 10.1038/ncb0506-427

By:

Mellone, Barbara;
Erhardt, Sylvia;
Karpen, Gary H.

Publication type:

Article

The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions.

Published in:

Nature Cell Biology, 2001, v. 3, n. 8, p. 730, doi. 10.1038/35087045

By:

Blower, Michael D.;
Karpen, Gary H.

Publication type:

Article

Impact of sequencing depth in ChIP-seq experiments.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 9, p. 1, doi. 10.1093/nar/gku178

By:

Youngsook L. Jung;
Luquette, Lovelace J.;
Ho, Joshua W. K.;
Ferrari, Francesco;
Tolstorukov, Michael;
Aki Minoda;
Issner, Robbyn;
Epstein, Charles B.;
Karpen, Gary H.;
Kuroda, Mitzi I.;
Park, Peter J.

Publication type:

Article

Impact of sequencing depth in ChIP-seq experiments.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 9, p. e74, doi. 10.1093/nar/gku178

By:

Jung, Youngsook L.;
Luquette, Lovelace J.;
Ho, Joshua W.K.;
Ferrari, Francesco;
Tolstorukov, Michael;
Minoda, Aki;
Issner, Robbyn;
Epstein, Charles B.;
Karpen, Gary H.;
Kuroda, Mitzi I.;
Park, Peter J.

Publication type:

Article

Nucleosomes Shape DNA Polymorphism and Divergence.

Published in:

PLoS Genetics, 2014, v. 10, n. 7, p. 1, doi. 10.1371/journal.pgen.1004457

By:

Langley, Sasha A.;
Karpen, Gary H.;
Langley, Charles H.

Publication type:

Article

Enrichment of HP1a on Drosophila Chromosome 4 Genes Creates an Alternate Chromatin Structure Critical for Regulation in this Heterochromatic Domain.

Published in:

PLoS Genetics, 2012, v. 8, n. 9, p. 1, doi. 10.1371/journal.pgen.1002954

By:

Riddle, Nicole C.;
Jung, Youngsook L.;
Gu, Tingting;
Alekseyenko, Artyom A.;
Asker, Dalal;
Hongxing Gui;
Kharchenko, Peter V.;
Minoda, Aki;
Plachetka, Annette;
Schwartz, Yuri B.;
Tolstorukov, Michael Y.;
Kuroda, Mitzi I.;
Pirrotta, Vincenzo;
Karpen, Gary H.;
Park, Peter J.;
Elgin, Sarah C. R.

Publication type:

Article

Sequence-Specific Targeting of Dosage Compensation in Drosophila Favors an Active Chromatin Context.

Published in:

PLoS Genetics, 2012, v. 8, n. 4, p. 1, doi. 10.1371/journal.pgen.1002646

By:

Alekseyenko, Artyom A.;
Ho, Joshua W. K.;
Shouyong Peng;
Gelbart, Marnie;
Tolstorukov, Michael Y.;
Plachetka, Annette;
Kharchenko, Peter V.;
Jung, Youngsook L.;
Gorchakov, Andrey A.;
Larschan, Erica;
Tingting Gu;
Minoda, Aki;
Riddle, Nicole C.;
Schwartz, Yuri B.;
Elgin, Sarah C. R.;
Karpen, Gary H.;
Pirrotta, Vincenzo;
Kuroda, Mitzi I.;
Park, Peter J.

Publication type:

Article

Assembly of Drosophila Centromeric Chromatin Proteins during Mitosis.

Published in:

PLoS Genetics, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.pgen.1002068

By:

Mellone, Barbara G.;
Grive, Kathryn J.;
Shteyn, Vladimir;
Bowers, Sarion R.;
Oderberg, Isaac;
Karpen, Gary H.

Publication type:

Article

Heterochromatic Genome Stability Requires Regulators of Histone H3 K9 Methylation.

Published in:

PLoS Genetics, 2009, v. 5, n. 3, p. 1, doi. 10.1371/journal.pgen.1000435

By:

Peng, Jamy C.;
Karpen, Gary H.

Publication type:

Article

Drosophila CENP-A Mutations Cause a BubR1- Dependent Early Mitotic Delay without Normal Localization of Kinetochore Components.

Published in:

PLoS Genetics, 2006, v. 3, n. 1, p. e110, doi. 10.1371/journal.pgen.0020110

By:

Blower, Michael D.;
Daigle, Tanya;
Kaufman, Thom;
Karpen, Gary H.

Publication type:

Article