Works by Karoly, Edward D.

Results: 35

SLC17A1/3 transporters mediate renal excretion of Lac-Phe in mice and humans.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51174-3

By:

Li, Veronica L.;
Xiao, Shuke;
Schlosser, Pascal;
Scherer, Nora;
Wiggenhorn, Amanda L.;
Spaas, Jan;
Tung, Alan Sheng-Hwa;
Karoly, Edward D.;
Köttgen, Anna;
Long, Jonathan Z.

Publication type:

Article

Metabolomics can spot the difference: Dried Blood Spot (DBS) coming of age in a metabolomics era.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R5469

By:

Heyman, Heino M.;
McCulloch, Scott D.;
Karoly, Edward D.;
Mitchell, Matthew W.;
Goodman, Kelli D.;
Evans, Anne M.

Publication type:

Article

Assessing the Role of Particulate Matter Size and Composition on Gene Expression in Pulmonary Cells.

Published in:

Inhalation Toxicology, 2007, v. 19, p. 23, doi. 10.1080/08958370701490551

By:

Graff, Donald W.;
Schmitt, Michael T.;
Dailey, Lisa A.;
Duvall, Rachelle M.;
Karoly, Edward D.;
Devlin, Robert B.

Publication type:

Article

Ozone-induced changes in the serum metabolome: Role of the microbiome.

Published in:

PLoS ONE, 2019, v. 14, n. 8, p. 1, doi. 10.1371/journal.pone.0221633

By:

Cho, Youngji;
Osgood, Ross S.;
Bell, Lauren N.;
Karoly, Edward D.;
Shore, Stephanie A.

Publication type:

Article

Ozone Exposure Increases Circulating Stress Hormones and Lipid Metabolites in Humans.

Published in:

2016

By:

Miller, Desinia B.;
Ghio, Andrew J.;
Karoly, Edward D.;
Bell, Lauren N.;
Snow, Samantha J.;
Madden, Michael C.;
Soukup, Joleen;
Cascio, Wayne E.;
Ian Gilmour, M.;
Kodavanti, Urmila P.;
Gilmour, M Ian

Publication type:

journal article

MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 1, p. 398, doi. 10.1172/JCI71180

By:

Terunuma, Atsushi;
Putluri, Nagireddy;
Mishra, Prachi;
Mathe, Ewy A.;
Dorsey, Tiffany H.;
Ming Yi;
Wallace, Tiffany A.;
Issaq, Haleem J.;
Ming Zhou;
Keith Killian, J.;
Stevenson, Holly S.;
Karoly, Edward D.;
King Chan;
Samanta, Susmita;
Prieto, DaRue;
Hsu, Tiffany Y.T.;
Kurley, Sarah J.;
Putluri, Vasanta;
Sonavane, Rajni;
Edelman, Daniel C.

Publication type:

Article

Inhibiting glycolytic metabolism enhances CD8<sup>+</sup> T cell memory and antitumor function.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 10, p. 4479, doi. 10.1172/JCI69589

By:

Sukumar, Madhusudhanan;
Jie Liu;
Yun Ji;
Subramanian, Murugan;
Crompton, Joseph G.;
Zhiya Yu;
Roychoudhuri, Rahul;
Palmer, Douglas C.;
Muranski, Pawel;
Karoly, Edward D.;
Mohney, Robert P.;
Klebanoff, Christopher A.;
Lal, Ashish;
Finkel, Toren;
Restifo, Nicholas P.;
Gattinoni, Luca

Publication type:

Article

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.

Published in:

2016

By:

Lotta, Luca A.;
Scott, Robert A.;
Sharp, Stephen J.;
Burgess, Stephen;
Luan, Jian’an;
Tillin, Therese;
Schmidt, Amand F.;
Imamura, Fumiaki;
Stewart, Isobel D.;
Perry, John R. B.;
Marney, Luke;
Koulman, Albert;
Karoly, Edward D.;
Forouhi, Nita G.;
Sjögren, Rasmus J. O.;
Näslund, Erik;
Zierath, Juleen R.;
Krook, Anna;
Savage, David B.;
Griffin, Julian L.

Publication type:

journal article

Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 1, p. 61, doi. 10.3390/metabo12010061

By:

Hysi, Pirro G.;
Mangino, Massimo;
Christofidou, Paraskevi;
Falchi, Mario;
Karoly, Edward D.;
Mohney, Robert P.;
Valdes, Ana M.;
Spector, Tim D.;
Menni, Cristina

Publication type:

Article

Comparison of Gene Expression Profiles Induced By Coarse, Fine, and Ultrafine Particulate Matter.

Published in:

Journal of Toxicology & Environmental Health: Part A, 2011, v. 74, n. 5, p. 296, doi. 10.1080/15287394.2010.516238

By:

Huang, Yuh-Chin T.;
Karoly, Edward D.;
Dailey, Lisa A.;
Schmitt, Michael T.;
Silbajoris, Robert;
Graff, Donald W.;
Devlin, Robert B.

Publication type:

Article

Effect of acute ozone exposure on the lung metabolomes of obese and lean mice.

Published in:

PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0181017

By:

Mathews, Joel Andrew;
Kasahara, David Itiro;
Cho, Youngji;
Bell, Lauren Nicole;
Gunst, Philip Ross;
Karoly, Edward D.;
Shore, Stephanie Ann

Publication type:

Article

Licofelone Modulates Neuroinflammation and Attenuates Mechanical Hypersensitivity in the Chronic Phase of Spinal Cord Injury.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 2, p. 652, doi. 10.1523/JNEUROSCI.6128-11.2013

By:

Dulin, Jennifer N.;
Karoly, Edward D.;
Ying Wang;
Strobel, Henry W.;
Grill, Raymond J.

Publication type:

Article

Metabolomics of dates (Phoenix dactylifera) reveals a highly dynamic ripening process accounting for major variation in fruit composition.

Published in:

BMC Plant Biology, 2015, v. 15, p. 1, doi. 10.1186/s12870-015-0672-5

By:

Diboun, Ilhame;
Mathew, Sweety;
Al-Rayyashi, Maryam;
Elrayess, Mohamed;
Torres, Maria;
Halama, Anna;
Méret, Michaël;
Mohney, Robert P.;
Karoly, Edward D.;
Malek, Joel;
Suhre, Karsten

Publication type:

Article

Oncogene-induced senescence results in marked metabolic and bioenergetic alterations.

Published in:

Cell Cycle, 2012, v. 11, n. 7, p. 1383, doi. 10.4161/cc.19800

By:

Quijano, Celia;
Liu Cao;
Fergusson, Maria M.;
Romero, Hector;
Jie Liu;
Gutkind, Sarah;
Rovira, Ilsa I.;
Mohney, Robert P.;
Karoly, Edward D.;
Finkel, Toren

Publication type:

Article

1,5-Anhydroglucitol in saliva is a noninvasive marker of short-term glycemic control.

Published in:

2014

By:

Mook-Kanamori, Dennis O;
Selim, Mohammed M El-Din;
Takiddin, Ahmed H;
Al-Homsi, Hala;
Al-Mahmoud, Khoulood A S;
Al-Obaidli, Amina;
Zirie, Mahmoud A;
Rowe, Jillian;
Yousri, Noha A;
Karoly, Edward D;
Kocher, Thomas;
Sekkal Gherbi, Wafaa;
Chidiac, Omar M;
Mook-Kanamori, Marjonneke J;
Abdul Kader, Sara;
Al Muftah, Wadha A;
McKeon, Cindy;
Suhre, Karsten

Publication type:

journal article

Changes in Metabolites Present in Lung-Lining Fluid Following Exposure of Humans to Ozone.

Published in:

Toxicological Sciences, 2018, v. 163, n. 2, p. 430, doi. 10.1093/toxsci/kfy043

By:

Cheng, WanYun;
Duncan, Kelly E;
Ghio, Andrew J;
Ward-Caviness, Cavin;
Karoly, Edward D;
Diaz-Sanchez, David;
Conolly, Rory B;
Devlin, Robert B

Publication type:

Article

The human Δ Np53 isoform triggers metabolic and gene expression changes that activate m TOR and alter mitochondrial function.

Published in:

Aging Cell, 2013, v. 12, n. 5, p. 863, doi. 10.1111/acel.12108

By:

Lin, Shih‐Chieh;
Karoly, Edward D.;
Taatjes, Dylan J.

Publication type:

Article

Metabolomic analysis of prostate cancer risk in a prospective cohort: The alpha-tocolpherol, beta-carotene cancer prevention (ATBC) study.

Published in:

International Journal of Cancer, 2015, v. 137, n. 9, p. 2124, doi. 10.1002/ijc.29576

By:

Mondul, Alison M.;
Moore, Steven C.;
Weinstein, Stephanie J.;
Karoly, Edward D.;
Sampson, Joshua N.;
Albanes, Demetrius

Publication type:

Article

Corrigendum: Landscape of the mitochondrial Hsp90 metabolome in tumours.

Published in:

Nature Communications, 2015, v. 6, n. 6, p. 7605, doi. 10.1038/ncomms8605

By:

Chae, Young Chan;
Angelin, Alessia;
Lisanti, Sofia;
Kossenkov, Andrew V.;
Speicher, Kaye D.;
Wang, Huan;
Powers, James F.;
Tischler, Arthur S.;
Pacak, Karel;
Fliedner, Stephanie;
Michalek, Ryan D.;
Karoly, Edward D.;
Wallace, Douglas C.;
Languino, Lucia R.;
Speicher, David W.;
Altieri, Dario C.

Publication type:

Article

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation.

Published in:

Nature Communications, 2015, v. 6, n. 3, p. 6692, doi. 10.1038/ncomms7692

By:

Patsoukis, Nikolaos;
Bardhan, Kankana;
Chatterjee, Pranam;
Sari, Duygu;
Liu, Bianling;
Bell, Lauren N.;
Karoly, Edward D.;
Freeman, Gordon J.;
Petkova, Victoria;
Seth, Pankaj;
Li, Lequn;
Boussiotis, Vassiliki A.

Publication type:

Article

Landscape of the mitochondrial Hsp90 metabolome in tumours.

Published in:

Nature Communications, 2013, v. 4, n. 7, p. 2139, doi. 10.1038/ncomms3139

By:

Chae, Young Chan;
Angelin, Alessia;
Lisanti, Sofia;
Kossenkov, Andrew V.;
Speicher, Kaye D.;
Wang, Huan;
Powers, James F.;
Tischler, Arthur S.;
Pacak, Karel;
Fliedner, Stephanie;
Michalek, Ryan D.;
Karoly, Edward D.;
Wallace, Douglas C.;
Languino, Lucia R.;
Speicher, David W.;
Altieri, Dario C.

Publication type:

Article

Serum Metabolomic Response to Long-Term Supplementation with all-rac-α-Tocopheryl Acetate in a Randomized Controlled Trial.

Published in:

Journal of Nutrition & Metabolism, 2016, p. 1, doi. 10.1155/2016/6158436

By:

Mondul, Alison M.;
Moore, Steven C.;
Weinstein, Stephanie J.;
Evans, Anne M.;
Karoly, Edward D.;
Männistö, Satu;
Sampson, Joshua N.;
Albanes, Demetrius

Publication type:

Article

Sequencing, expression, and characterization of cDNA expressed flavin-containing monooxygenase 2 from mouse.

Published in:

Journal of Biochemical & Molecular Toxicology, 2001, v. 15, n. 6, p. 300, doi. 10.1002/jbt.10009

By:

Karoly, Edward D.;
Rose, Randy L.

Publication type:

Article

Offspring susceptibility to metabolic alterations due to maternal high-fat diet and the impact of inhaled ozone used as a stressor.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73361-0

By:

Snow, Samantha J.;
Broniowska, Katarzyna;
Karoly, Edward D.;
Henriquez, Andres R.;
Phillips, Pamela M.;
Ledbetter, Allen D.;
Schladweiler, Mette C.;
Miller, Colette N.;
Gordon, Christopher J.;
Kodavanti, Urmila P.

Publication type:

Article

Large-Scaled Metabolic Profiling of Human Dermal Fibroblasts Derived from Pseudoxanthoma Elasticum Patients and Healthy Controls.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108336

By:

Kuzaj, Patricia;
Kuhn, Joachim;
Michalek, Ryan D.;
Karoly, Edward D.;
Faust, Isabel;
Dabisch-Ruthe, Mareike;
Knabbe, Cornelius;
Hendig, Doris

Publication type:

Article

Inactivation of Metabolic Genes Causes Short- and Long-Range dys-Regulation in <i>Escherichia coli</i> Metabolic Network.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0078360

By:

Barupal, Dinesh Kumar;
Lee, Sang Jun;
Karoly, Edward D.;
Adhya, Sankar

Publication type:

Article

HuR is a post-transcriptional regulator of core metabolic enzymes in pancreatic cancer.

Published in:

RNA Biology, 2013, v. 10, n. 8, p. 1312, doi. 10.4161/rna.25274

By:

Burkhart, Richard A.;
Pineda, Danielle M.;
Chand, Saswati N.;
Romeo, Carmella;
Londin, Eric R.;
Karoly, Edward D.;
Cozzitorto, Joseph A.;
Rigoutsos, Isidore;
Yeo, Charles J.;
Brody, Jonathan R.;
Winter, Jordan M.

Publication type:

Article

One-Month Diesel Exhaust Inhalation Produces Hypertensive Gene Expression Pattern in Healthy Rats.

Published in:

Environmental Health Perspectives, 2009, v. 117, n. 1, p. 38, doi. 10.1289/ehp.11647

By:

Gottipolu, Reddy R.;
Wallenborn, J. Grace;
Karoly, Edward D.;
Schladweiler, Mette C.;
Ledbetter, Allen D.;
Krantz, Todd;
Linak, William P.;
Nyska, Abraham;
Johnson, Jo Anne;
Thomas, Ronald;
Richards, Judy E.;
Jaskot, Richard H.;
Kodavanti, Urmila P.

Publication type:

Article

The Role of Particulate Matter-Associated Zinc in Cardiac Injury in Rats.

Published in:

Environmental Health Perspectives, 2008, v. 116, n. 1, p. 13, doi. 10.1289/ehp.10379

By:

Kodavanti, Urmila P.;
Schladweiler, Mette C.;
Gilmour, Peter S.;
Wallenborn, J. Grace;
Mandavilli, Bhaskar S.;
Ledbetter, Allen D.;
Christiani, David C.;
Runge, Marschall S.;
Karoly, Edward D.;
Costa, Daniel L.;
Peddada, Shyamal;
Jaskot, Richard;
Richards, Judy H.;
Thomas, Ronald;
Madamanchi, Nageswara R.;
Nyska, Abraham

Publication type:

Article

Up-regulation of Tissue Factor in Human Pulmonary Artery Endothelial Cells after Ultrafine Particle Exposure.

Published in:

Environmental Health Perspectives, 2007, v. 115, n. 4, p. 535, doi. 10.1289/ehp.9556

By:

Karoly, Edward D.;
Zhuowei Li;
Dailey, Lisa A.;
Xhevahire Hyseni;
Huang, Yuh-Chin T.

Publication type:

Article

Metabolic signatures differentiate ovarian from colon cancer cell lines.

Published in:

Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0576-z

By:

Halama, Anna;
Guerrouahen, Bella S.;
Pasquier, Jennifer;
Diboun, Ilhem;
Karoly, Edward D.;
Suhre, Karsten;
Rafii, Arash

Publication type:

Article

Metabolomic Differences in Heart Failure Patients With and Without Major Depression.

Published in:

Journal of Geriatric Psychiatry & Neurology, 2010, v. 23, n. 2, p. 138, doi. 10.1177/0891988709358592

By:

Steffens, David C.;
Wei Jiang;
Krishnan, K. Ranga R.;
Karoly, Edward D.;
Mitchell, Matthew W.;
O'Connor, Christopher M.;
Kaddurah-Daouk, Rima

Publication type:

Article

Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism.

Published in:

Scientific Reports, 2016, p. 38489, doi. 10.1038/srep38489

By:

James, Emma L.;
Lane, James A. E.;
Michalek, Ryan D.;
Karoly, Edward D.;
Parkinson, E. Kenneth

Publication type:

Article

High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12298-z

By:

Labbé, David P.;
Zadra, Giorgia;
Yang, Meng;
Reyes, Jaime M.;
Lin, Charles Y.;
Cacciatore, Stefano;
Ebot, Ericka M.;
Creech, Amanda L.;
Giunchi, Francesca;
Fiorentino, Michelangelo;
Elfandy, Habiba;
Syamala, Sudeepa;
Karoly, Edward D.;
Alshalalfa, Mohammed;
Erho, Nicholas;
Ross, Ashley;
Schaeffer, Edward M.;
Gibb, Ewan A.;
Takhar, Mandeep;
Den, Robert B.

Publication type:

Article

Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study.

Published in:

Kidney International, 2014, v. 85, n. 5, p. 1214, doi. 10.1038/ki.2013.497

By:

Niewczas, Monika A;
Sirich, Tammy L;
Mathew, Anna V;
Skupien, Jan;
Mohney, Robert P;
Warram, James H;
Smiles, Adam;
Huang, Xiaoping;
Walker, Walker;
Byun, Jaeman;
Karoly, Edward D;
Kensicki, Elizabeth M;
Berry, Gerard T;
Bonventre, Joseph V;
Pennathur, Subramaniam;
Meyer, Timothy W;
Krolewski, Andrzej S

Publication type:

Article