Found: 156

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  • P‐tau235: a novel biomarker for staging preclinical Alzheimer's disease.

    Published in:
    EMBO Molecular Medicine, 2021, v. 13, n. 12, p. 1, doi. 10.15252/emmm.202115098
    By:
    • Lantero‐Rodriguez, Juan;
    • Snellman, Anniina;
    • Benedet, Andrea L;
    • Milà‐Alomà, Marta;
    • Camporesi, Elena;
    • Montoliu‐Gaya, Laia;
    • Ashton, Nicholas J;
    • Vrillon, Agathe;
    • Karikari, Thomas K;
    • Gispert, Juan Domingo;
    • Salvadó, Gemma;
    • Shekari, Mahnaz;
    • Toomey, Christina E;
    • Lashley, Tammaryn L;
    • Zetterberg, Henrik;
    • Suárez‐Calvet, Marc;
    • Brinkmalm, Gunnar;
    • Rosa Neto, Pedro;
    • Blennow, Kaj
    Publication type:
    Article

  • Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer's continuum when only subtle changes in Aβ pathology are detected.

    Published in:
    EMBO Molecular Medicine, 2020, v. 12, n. 12, p. 1, doi. 10.15252/emmm.202012921
    By:
    • Suárez‐Calvet, Marc;
    • Karikari, Thomas K;
    • Ashton, Nicholas J;
    • Lantero Rodríguez, Juan;
    • Milà‐Alomà, Marta;
    • Gispert, Juan Domingo;
    • Salvadó, Gemma;
    • Minguillon, Carolina;
    • Fauria, Karine;
    • Shekari, Mahnaz;
    • Grau‐Rivera, Oriol;
    • Arenaza‐Urquijo, Eider M;
    • Sala‐Vila, Aleix;
    • Sánchez‐Benavides, Gonzalo;
    • González‐de‐Echávarri, José Maria;
    • Kollmorgen, Gwendlyn;
    • Stoops, Erik;
    • Vanmechelen, Eugeen;
    • Zetterberg, Henrik;
    • Blennow, Kaj
    Publication type:
    Article

  • Blood–brain barrier opening of the default mode network in Alzheimer's disease with magnetic resonance-guided focused ultrasound.

    Published in:
    Brain: A Journal of Neurology, 2023, v. 146, n. 3, p. 865, doi. 10.1093/brain/awac459
    By:
    • Meng, Ying;
    • Goubran, Maged;
    • Rabin, Jennifer S;
    • McSweeney, Melissa;
    • Ottoy, Julie;
    • Pople, Christopher B;
    • Huang, Yuexi;
    • Storace, Alexandra;
    • Ozzoude, Miracle;
    • Bethune, Allison;
    • Lam, Benjamin;
    • Swardfager, Walter;
    • Heyn, Chinthaka;
    • Abrahao, Agessandro;
    • Davidson, Benjamin;
    • Hamani, Clement;
    • Aubert, Isabelle;
    • Zetterberg, Henrik;
    • Ashton, Nicholas J;
    • Karikari, Thomas K
    Publication type:
    Article

  • Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration.

    Published in:
    Brain: A Journal of Neurology, 2023, v. 146, n. 3, p. 1152, doi. 10.1093/brain/awac407
    By:
    • Gonzalez-Ortiz, Fernando;
    • Turton, Michael;
    • Kac, Przemysław R;
    • Smirnov, Denis;
    • Premi, Enrico;
    • Ghidoni, Roberta;
    • Benussi, Luisa;
    • Cantoni, Valentina;
    • Saraceno, Claudia;
    • Rivolta, Jasmine;
    • Ashton, Nicholas J;
    • Borroni, Barbara;
    • Galasko, Douglas;
    • Harrison, Peter;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Karikari, Thomas K
    Publication type:
    Article

  • Ante-mortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy.

    Published in:
    2022
    By:
    • Morrison, Madeline S;
    • Aparicio, Hugo J;
    • Blennow, Kaj;
    • Zetterberg, Henrik;
    • Ashton, Nicholas J;
    • Karikari, Thomas K;
    • Tripodis, Yorghos;
    • Martin, Brett;
    • Palmisano, Joseph N;
    • Sugarman, Michael A;
    • Frank, Brandon;
    • Steinberg, Eric G;
    • Turk, Katherine W;
    • Budson, Andrew E;
    • Au, Rhoda;
    • Goldstein, Lee E;
    • Jun, Gyungah R;
    • Kowall, Neil W;
    • Killiany, Ronald;
    • Qiu, Wei Qiao
    Publication type:
    journal article

  • N-terminal and mid-region tau fragments as fluid biomarkers in neurological diseases.

    Published in:
    2022
    By:
    • Snellman, Anniina;
    • Lantero-Rodriguez, Juan;
    • Emeršič, Andreja;
    • Vrillon, Agathe;
    • Karikari, Thomas K;
    • Ashton, Nicholas J;
    • Kramberger, Milica Gregorič;
    • Čučnik, Saša;
    • Paquet, Claire;
    • Rot, Uroš;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Gregorič Kramberger, Milica
    Publication type:
    journal article

  • Population-based blood screening for preclinical Alzheimer's disease in a British birth cohort at age 70.

    Published in:
    2021
    By:
    • Keshavan, Ashvini;
    • Pannee, Josef;
    • Karikari, Thomas K;
    • Rodriguez, Juan Lantero;
    • Ashton, Nicholas J;
    • Nicholas, Jennifer M;
    • Cash, David M;
    • Coath, William;
    • Lane, Christopher A;
    • Parker, Thomas D;
    • Lu, Kirsty;
    • Buchanan, Sarah M;
    • Keuss, Sarah E;
    • James, Sarah-Naomi;
    • Murray-Smith, Heidi;
    • Wong, Andrew;
    • Barnes, Anna;
    • Dickson, John C;
    • Heslegrave, Amanda;
    • Portelius, Erik
    Publication type:
    journal article

  • Time course of phosphorylated-tau181 in blood across the Alzheimer's disease spectrum.

    Published in:
    2021
    By:
    • Moscoso, Alexis;
    • Grothe, Michel J;
    • Ashton, Nicholas J;
    • Karikari, Thomas K;
    • Rodriguez, Juan Lantero;
    • Snellman, Anniina;
    • Suárez-Calvet, Marc;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Schöll, Michael;
    • Initiative, for the Alzheimer's Disease Neuroimaging;
    • Alzheimer’s Disease Neuroimaging Initiative
    Publication type:
    journal article

  • Cerebrospinal fluid p‐tau181, 217, and 231 in definite Creutzfeldt–Jakob disease with and without concomitant pathologies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5324, doi. 10.1002/alz.13907
    By:
    • Emeršič, Andreja;
    • Ashton, Nicholas J.;
    • Vrillon, Agathe;
    • Lantero‐Rodriguez, Juan;
    • Mlakar, Jernej;
    • Gregorič Kramberger, Milica;
    • Gonzalez‐Ortiz, Fernando;
    • Kac, Przemysław R.;
    • Dulewicz, Maciej;
    • Hanrieder, Jörg;
    • Vanmechelen, Eugeen;
    • Rot, Uroš;
    • Zetterberg, Henrik;
    • Karikari, Thomas K.;
    • Čučnik, Saša;
    • Blennow, Kaj
    Publication type:
    Article

  • Association of plasma biomarkers of Alzheimer's disease and related disorders with cognition and cognitive decline: The MYHAT population‐based study.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 4199, doi. 10.1002/alz.13829
    By:
    • Zhang, Yingjin;
    • Ferreira, Pamela C. L.;
    • Jacobsen, Erin;
    • Bellaver, Bruna;
    • Pascoal, Tharick A.;
    • Snitz, Beth E.;
    • Chang, Chung‐Chou H.;
    • Villemagne, Victor L.;
    • Ganguli, Mary;
    • Karikari, Thomas K.
    Publication type:
    Article

  • Novel ultrasensitive immunoassay for the selective quantification of tau oligomers and related soluble aggregates.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2894, doi. 10.1002/alz.13711
    By:
    • Islam, Tohidul;
    • Kvartsberg, Hlin;
    • Sehrawat, Anuradha;
    • Kac, Przemysław R.;
    • Becker, Bruno;
    • Olsson, Maria;
    • Abrahamson, Eric E.;
    • Zetterberg, Henrik;
    • Ikonomovic, Milos D.;
    • Blennow, Kaj;
    • Karikari, Thomas K.
    Publication type:
    Article

  • Analytical and clinical validation of Alzheimer's disease blood biomarkers with a focus on plasma p‐tau217.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 3114, doi. 10.1002/alz.13708
    By:
    • Gonzalez‐Ortiz, Fernando;
    • Karikari, Thomas K.;
    • Blennow, Kaj
    Publication type:
    Article

  • Plasma pTau‐217 and N‐terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid‐β positive individuals.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 2, p. 1166, doi. 10.1002/alz.13528
    By:
    • Woo, Marcel S.;
    • Tissot, Cécile;
    • Lantero‐Rodriguez, Juan;
    • Snellman, Anniina;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Macedo, Arthur C.;
    • Servaes, Stijn;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Hosseini, Seyyed Ali;
    • Chamoun, Mira;
    • Lussier, Firoza Z.;
    • Benedet, Andrea L.;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K.;
    • Triana‐Baltzer, Gallen;
    • Kolb, Hartmuth C.;
    • Stevenson, Jenna;
    • Mayer, Christina
    Publication type:
    Article

  • Biological variation estimates of Alzheimer's disease plasma biomarkers in healthy individuals.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 2, p. 1284, doi. 10.1002/alz.13518
    By:
    • Brum, Wagner S.;
    • Ashton, Nicholas J.;
    • Simrén, Joel;
    • di Molfetta, Guiglielmo;
    • Karikari, Thomas K.;
    • Benedet, Andrea L.;
    • Zimmer, Eduardo R.;
    • Lantero‐Rodriguez, Juan;
    • Montoliu‐Gaya, Laia;
    • Jeromin, Andreas;
    • Aarsand, Aasne K.;
    • Bartlett, William A.;
    • Calle, Pilar Fernández;
    • Coşkun, Abdurrahman;
    • Díaz–Garzón, Jorge;
    • Jonker, Niels;
    • Zetterberg, Henrik;
    • Sandberg, Sverre;
    • Carobene, Anna;
    • Blennow, Kaj
    Publication type:
    Article

  • Levels of plasma brain‐derived tau and p‐tau181 in Alzheimer's disease and rapidly progressive dementias.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 1, p. 745, doi. 10.1002/alz.13516
    By:
    • Gonzalez‐Ortiz, Fernando;
    • Karikari, Thomas K.;
    • Bentivenga, Giuseppe Mario;
    • Baiardi, Simone;
    • Mammana, Angela;
    • Turton, Michael;
    • Kac, Przemysław R.;
    • Mastrangelo, Andrea;
    • Harrison, Peter;
    • Capellari, Sabina;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Parchi, Piero
    Publication type:
    Article

  • Independent associations of plasma GFAP with amyloid‐β and tau in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083173
    By:
    • Jia, Wan Lu;
    • Rahmouni, Nesrine;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Therriault, Joseph;
    • Macedo, Arthur C.;
    • Arias, Jaime Fernandez;
    • Wang, Yi‐Ting;
    • Lussier, Firoza Z;
    • Kunach, Peter;
    • Gauthier, Serge;
    • Zimmer, Eduardo R;
    • Karikari, Thomas K;
    • Benedet, Andrea L.;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik;
    • Pascoal, Tharick A.;
    • Blennow, Kaj;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Optimizing plasma biomarkers combinations for the detection of amyloid pathology in cognitively unimpaired individuals.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082742
    By:
    • Contador, José;
    • Milà‐Alomà, Marta;
    • Escalante, Armand González;
    • Ashton, Nicholas J.;
    • Shekari, Mahnaz;
    • Ortiz‐Romero, Paula;
    • Karikari, Thomas K;
    • Vanmechelen, Eugeen;
    • Day, Theresa A.;
    • Dage, Jeff L.;
    • Zetterberg, Henrik;
    • Gispert, Juan Domingo;
    • Blennow, Kaj;
    • Suárez‐Calvet, Marc
    Publication type:
    Article

  • Increased Genetic Risk for ADHD Potentiates Cognitive Impairment and Brain Hypometabolism in Alzheimer's Disease Patients.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080519
    By:
    • Leffa, Douglas Teixeira;
    • Povala, Guilherme;
    • Bellaver, Bruna;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Ferreira, Pamela C.L.;
    • Zalzale, Hussein;
    • Aguzzoli, Cristiano Schaffer;
    • Rohden, Francieli;
    • Soares, Carolina;
    • Abbas, Sarah;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Lopez, Oscar L.;
    • Villemagne, Victor L;
    • Klunk, William E;
    • Cohen, Annie;
    • Zimmer, Eduardo R.;
    • Karikari, Thomas K;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Interactions of synaptic and inflammatory biomarkers in Alzheimer's Disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080593
    By:
    • Rahmouni, Nesrine;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Therriault, Joseph;
    • Macedo, Arthur C.;
    • Stevenson, Jenna;
    • Lussier, Firoza Z;
    • Machado, Luiza Santos;
    • Arias, Jaime Fernandez;
    • Wang, Yi‐Ting;
    • Stevenson, Alyssa;
    • Socualaya, Kely Quispialaya;
    • Kunach, Peter;
    • Nazneen, Tahnia;
    • Hosseini, Seyyed Ali;
    • Gauthier, Serge;
    • Karikari, Thomas K;
    • Benedet, Andrea Lessa;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik
    Publication type:
    Article

  • Fast accumulators of tau have higher levels of plasma pTau and stronger associations with amyloid in later Braak regions at baseline.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079999
    By:
    • Servaes, Stijn;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Lussier, Firoza Z;
    • Ashton, Nicholas J.;
    • Benedet, Andrea Lessa;
    • Karikari, Thomas K;
    • Wang, Yi‐Ting;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Stevenson, Alyssa;
    • Pallen, Vanessa;
    • Arias, Jaime Fernandez;
    • Macedo, Arthur C.;
    • Nazneen, Tahnia;
    • Hosseini, Seyyed Ali;
    • Triana‐Baltzer, Gallen;
    • Kolb, Hartmuth C.;
    • Pascoal, Tharick A.;
    • Gauthier, Serge
    Publication type:
    Article

  • Increased regional brain inflammation predicts longitudinal brain atrophy in individuals in the Alzheimer's disease continuum.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079000
    By:
    • Povala, Guilherme;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Leffa, Douglas Teixeira;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Benedet, Andrea Lessa;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Cohen, Ann D.;
    • Lopez, Oscar L.;
    • Tudorascu, Dana;
    • Klunk, William E;
    • Villemagne, Victor L;
    • Karikari, Thomas K;
    • Zimmer, Eduardo R
    Publication type:
    Article

  • Amyloid‐dependent tau phosphorylation drives faster accumulation of tau aggregates in female.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078657
    By:
    • Wang, Yi‐Ting;
    • Therriault, Joseph;
    • Servaes, Stijn;
    • Tissot, Cécile;
    • Rahmouni, Nesrine;
    • Arias, Jaime Fernandez;
    • Benedet, Andrea Lessa;
    • Mathotaarachchi, Sulantha;
    • Stevenson, Jenna;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Exploring biomarker profiles of the cognitively unimpaired individuals in early tau PET Braak stage.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077921
    By:
    • Shekari, Mahnaz;
    • González Escalante, Armand;
    • Milà‐Alomà, Marta;
    • Falcon, Carles;
    • López‐Martos, David;
    • Sánchez‐Benavides, Gonzalo;
    • Brugulat‐Serrat, Anna;
    • Ni, Aida;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Rodriguez, Juan Lantero;
    • Snellman, Anniina;
    • Day, Theresa A.;
    • Dage, Jeffrey L;
    • Ortiz‐Romero, Paula;
    • Tonietto, Matteo;
    • Borroni, Edilio;
    • Klein, Gregory;
    • Kollmorgen, Gwendlyn;
    • Carboni, Margherita
    Publication type:
    Article

  • The impact of young controls in the detection of tau load in cognitively impaired and asymptomatic elderly.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076833
    By:
    • Macedo, Arthur C.;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Servaes, Stijn;
    • Arias, Jaime Fernandez;
    • Wang, Yi‐Ting;
    • Aumont, Etienne;
    • Socualaya, Kely Quispialaya;
    • Lussier, Firoza Z;
    • Stevenson, Jenna;
    • Nazneen, Tahnia;
    • Hosseini, Seyyed Ali;
    • Karikari, Thomas K;
    • Benedet, Andrea Lessa;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Pascoal, Tharick A.;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Investigating Potential Racial Differences in Dementia‐Related Plasma Biomarkers.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080261
    By:
    • Pettway, Erika C;
    • Labonte, Jacob;
    • II, Robert W Turner;
    • Bragg, Tahlia;
    • Turner, Arlener;
    • Banks, Sarah J;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Tripodis, Yorghos;
    • Martin, Brett M;
    • Palmisano, Joseph N;
    • Stern, Robert A;
    • Killiany, Ronald J;
    • Aparicio, Hugo J;
    • Goldstein, Lee E;
    • Qiu, Wendy;
    • Budson, Andrew E;
    • Mez, Jesse B.
    Publication type:
    Article

  • Plasma biomarkers of tau for the differentiation between slow and fast tau‐PET accumulators.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080098
    By:
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Wang, Yi‐Ting;
    • Stevenson, Jenna;
    • Snellman, Anniina;
    • Rodriguez, Juan Lantero;
    • Stevenson, Alyssa;
    • Arias, Jaime Fernandez;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Mathotaarachchi, Sulantha;
    • Bezgin, Gleb;
    • Kunach, Peter;
    • Triana‐Baltzer, Gallen;
    • Gauthier, Serge;
    • Karikari, Thomas K;
    • Kolb, Hartmuth C.
    Publication type:
    Article

  • Microtubule‐binding region tau fragment tau368 as a biomarker of Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079611
    By:
    • Simrén, Joel;
    • Janelidze, Shorena;
    • Kac, Przemyslaw Radoslaw;
    • Karikari, Thomas K;
    • Smirnov, Denis;
    • Kvartsberg, Hlin;
    • Gonzalez‐Ortiz, Fernando;
    • Sjons, Emma;
    • Mattsson‐Carlgren, Niklas;
    • Brum, Wagner Scheeren;
    • Palmqvist, Sebastian;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik;
    • Galasko, Douglas R.;
    • Hansson, Oskar;
    • Blennow, Kaj
    Publication type:
    Article

  • The role of biofluid markers in predicting near‐term cognitive impairment.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079372
    By:
    • Yakoub, Yara;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Montoliu‐Gaya, Laia;
    • Schöll, Michael;
    • Spreng, R. Nathan;
    • Rosa‐Neto, Pedro;
    • Soucy, Jean‐Paul;
    • Breitner, John C.S.;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Poirier, Judes;
    • Villeneuve, Sylvia
    Publication type:
    Article

  • Examination of plasma YKL‐40 as a clinical biomarker for Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078885
    By:
    • Sugarman, Michael A;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Pase, Matthew P.;
    • Himali, Jayandra Jung;
    • Beiser, Alexa S.;
    • Seshadri, Sudha;
    • Budson, Andrew E;
    • O'Connor, Maureen K.;
    • Au, Rhoda;
    • Goldstein, Lee E;
    • Qiu, Wei Qiao;
    • Kowall, Neil W;
    • Stern, Robert A;
    • McKee, Ann C.;
    • Mez, Jesse B.;
    • Alosco, Michael L;
    • Aparicio, Hugo J
    Publication type:
    Article

  • Plasma Alzheimer biomarkers in the 1946 British birth cohort: predicting conversion to amyloid PET positivity over a two‐year follow‐up period.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078425
    By:
    • Keshavan, Ashvini;
    • Camporesi, Elena;
    • Coath, William;
    • Cash, David M;
    • Fox, Nick C;
    • Karikari, Thomas K;
    • Ashton, Nicholas J.;
    • Blennow, Kaj;
    • Zetterberg, Henrik;
    • Schott, Jonathan M
    Publication type:
    Article

  • Cognitively Unimpaired Multiparous Women Have Higher CSF p‐tau181 Levels Which Have More Deleterious Effects on Neurodegeneration and Executive Function.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078157
    By:
    • Brugulat‐Serrat, Anna;
    • Escalante, Armand González;
    • Sánchez‐Benavides, Gonzalo;
    • Milà‐Alomà, Marta;
    • Shekari, Mahnaz;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Kollmorgen, Gwendlyn;
    • Carmona, Susana;
    • Falcon, Carles;
    • Cacciaglia, Raffaele;
    • Anastasi, Federica;
    • Grau‐Rivera, Oriol;
    • Carboni, Margherita;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Suarez‐Calvet, Marc;
    • Gispert, Juan Domingo
    Publication type:
    Article

  • Plasma p‐tau forms as potential diagnostic biomarkers for Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077124
    By:
    • Kulczynska‐Przybik, Agnieszka;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Dulewicz, Maciej;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Mroczko, Jan;
    • Borawska, Renata;
    • Slowik, Agnieszka;
    • Mroczko, Barbara
    Publication type:
    Article

  • The clinical usefulness of plasma biomarkers of neuronal dysfunction in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076874
    By:
    • Mroczko, Barbara;
    • Kulczynska‐Przybik, Agnieszka;
    • Blennow, Kaj;
    • Dulewicz, Maciej;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Mroczko, Jan;
    • Borawska, Renata;
    • Slowik, Agnieszka;
    • Zetterberg, Henrik
    Publication type:
    Article

  • Development and implementation of plasma P‐tau immunoassays.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080658
    By:
    • Karikari, Thomas K
    Publication type:
    Article

  • Plasma biomarkers as stand‐alone tests in the diagnosis of Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080181
    By:
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • González Escalante, Armand;
    • Jonaitis, Erin M.;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Rahmouni, Nesrine;
    • Lussier, Firoza Z;
    • Stevenson, Jenna;
    • Milà‐Alomà, Marta;
    • Pascoal, Tharick A.;
    • Vitali, Paolo;
    • Gauthier, Serge;
    • Zetterberg, Henrik;
    • Johnson, Sterling C.;
    • Blennow, Kaj;
    • Suarez‐Calvet, Marc;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • Plasma biomarkers rates of change across the preclinical stage of Alzheimer's disease: a longitudinal study.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079638
    By:
    • González Escalante, Armand;
    • Milà‐Alomà, Marta;
    • Ashton, Nicholas J.;
    • Shekari, Mahnaz;
    • Salvadó, Gemma;
    • Ortiz‐Romero, Paula;
    • Montoliu‐Gaya, Laia;
    • Benedet, Andrea Lessa;
    • Karikari, Thomas K;
    • Rodriguez, Juan Lantero;
    • Vanmechelen, Eugeen;
    • Sánchez‐Benavides, Gonzalo;
    • Minguillon, Carolina;
    • Fauria, Karine;
    • Molinuevo, Jose Luis;
    • Zetterberg, Henrik;
    • del Campo, Marta;
    • Gispert, Juan Domingo;
    • Blennow, Kaj;
    • Vilor‐Tejedor, Natalia
    Publication type:
    Article

  • Plasma biomarkers in relation to spatial distribution of Alzheimer's disease neuropathology.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078416
    By:
    • Bilgel, Murat;
    • Shah, Ishaan;
    • Walker, Keenan A.;
    • Moghekar, Abhay;
    • Ashton, Nicholas J.;
    • Kac, Przemyslaw Radoslaw;
    • Karikari, Thomas K;
    • Blennow, Kaj;
    • Zetterberg, Henrik;
    • Thambisetty, Madhav;
    • Ferrucci, Luigi;
    • Resnick, Susan M.
    Publication type:
    Article

  • Plasma p‐tau212 is an early biomarker to identify Alzheimer's Disease pathology in Down Syndrome.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076229
    By:
    • Kac, Przemyslaw Radoslaw;
    • Alcolea, Daniel;
    • Montoliu‐Gaya, Laia;
    • Rodriguez, Juan Lantero;
    • Gonzalez‐Ortiz, Fernando;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik;
    • Karikari, Thomas K;
    • Fortea, Juan;
    • Blennow, Kaj
    Publication type:
    Article

  • Sex Differences on Tau, Astrocytic and Neurodegeneration Plasma Biomarkers.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071807
    By:
    • Labonte, Jacob;
    • Pettway, Erika C;
    • Sugarman, Michael;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Tripodis, Yorghos;
    • Martin, Brett M;
    • Palmisano, Joseph N;
    • Stern, Robert A;
    • Killiany, Ronald J;
    • Aparicio, Hugo J;
    • Goldstein, Lee E;
    • Qiu, Wendy;
    • Mez, Jesse B.;
    • Banks, Sarah J;
    • Alosco, Michael L
    Publication type:
    Article

  • Interactions of synaptic and inflammatory biomarkers in Alzheimer's Disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.082018
    By:
    • Rahmouni, Nesrine;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Therriault, Joseph;
    • Macedo, Arthur C.;
    • Stevenson, Jenna;
    • Lussier, Firoza Z;
    • Machado, Luiza Santos;
    • Arias, Jaime Fernandez;
    • Wang, Yi‐Ting;
    • Stevenson, Alyssa;
    • Socualaya, Kely Quispialaya;
    • Kunach, Peter;
    • Nazneen, Tahnia;
    • Hosseini, Seyyed Ali;
    • Gauthier, Serge;
    • Karikari, Thomas K;
    • Benedet, Andrea Lessa;
    • Ashton, Nicholas J.;
    • Zetterberg, Henrik
    Publication type:
    Article

  • Plasma biomarkers of tau for the differentiation between slow and fast tau‐PET accumulators.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081969
    By:
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Rahmouni, Nesrine;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Wang, Yi‐Ting;
    • Stevenson, Jenna;
    • Snellman, Anniina;
    • Rodriguez, Juan Lantero;
    • Stevenson, Alyssa;
    • Arias, Jaime Fernandez;
    • Lussier, Firoza Z;
    • Chamoun, Mira;
    • Mathotaarachchi, Sulantha;
    • Bezgin, Gleb;
    • Kunach, Peter;
    • Triana‐Baltzer, Gallen;
    • Gauthier, Serge;
    • Karikari, Thomas K;
    • Kolb, Hartmuth C.
    Publication type:
    Article

  • The role of biofluid markers in predicting near‐term cognitive impairment.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081897
    By:
    • Yakoub, Yara;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Montoliu‐Gaya, Laia;
    • Schöll, Michael;
    • Spreng, R. Nathan;
    • Rosa‐Neto, Pedro;
    • Soucy, Jean‐Paul;
    • Breitner, John C.S.;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Poirier, Judes;
    • Villeneuve, Sylvia
    Publication type:
    Article

  • Increased regional brain inflammation predicts longitudinal brain atrophy in individuals in the Alzheimer's disease continuum.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081863
    By:
    • Povala, Guilherme;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Leffa, Douglas Teixeira;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Benedet, Andrea Lessa;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Cohen, Ann D.;
    • Lopez, Oscar L.;
    • Tudorascu, Dana;
    • Klunk, William E;
    • Villemagne, Victor L;
    • Karikari, Thomas K;
    • Zimmer, Eduardo R
    Publication type:
    Article

  • Plasma biomarkers in relation to spatial distribution of Alzheimer's disease neuropathology.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081810
    By:
    • Bilgel, Murat;
    • Shah, Ishaan;
    • Walker, Keenan A.;
    • Moghekar, Abhay;
    • Ashton, Nicholas J.;
    • Kac, Przemyslaw Radoslaw;
    • Karikari, Thomas K;
    • Blennow, Kaj;
    • Zetterberg, Henrik;
    • Thambisetty, Madhav;
    • Ferrucci, Luigi;
    • Resnick, Susan M.
    Publication type:
    Article

  • Exploring biomarker profiles of the cognitively unimpaired individuals in early tau PET Braak stage.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081775
    By:
    • Shekari, Mahnaz;
    • Escalante, Armand González;
    • Milà‐Alomà, Marta;
    • Falcon, Carles;
    • López‐Martos, David;
    • Sánchez‐Benavides, Gonzalo;
    • Brugulat‐Serrat, Anna;
    • Niñerola‐Baizán, Aida;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Rodriguez, Juan Lantero;
    • Snellman, Anniina;
    • Day, Theresa A.;
    • Dage, Jeffrey L;
    • Ortiz‐Romero, Paula;
    • Tonietto, Matteo;
    • Borroni, Edilio;
    • Klein, Gregory;
    • Kollmorgen, Gwendlyn;
    • Carboni, Margherita
    Publication type:
    Article

  • Longitudinal blood biomarker trajectories in preclinical Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 12, p. 5620, doi. 10.1002/alz.13318
    By:
    • Yakoub, Yara;
    • Ashton, Nicholas J.;
    • Strikwerda‐Brown, Cherie;
    • Montoliu‐Gaya, Laia;
    • Karikari, Thomas K.;
    • Kac, Przemysław R.;
    • Gonzalez‐Ortiz, Fernando;
    • Gallego‐Rudolf, Jonathan;
    • Meyer, Pierre‐François;
    • St‐Onge, Frédéric;
    • Schöll, Michael;
    • Soucy, Jean‐Paul;
    • Breitner, John C. S.;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Poirier, Judes;
    • Villeneuve, Sylvia
    Publication type:
    Article

  • Equivalence of plasma p‐tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 11, p. 4967, doi. 10.1002/alz.13026
    By:
    • Therriault, Joseph;
    • Servaes, Stijn;
    • Tissot, Cécile;
    • Rahmouni, Nesrine;
    • Ashton, Nicholas J.;
    • Benedet, Andréa Lessa;
    • Karikari, Thomas K.;
    • Macedo, Arthur C.;
    • Lussier, Firoza Z.;
    • Stevenson, Jenna;
    • Wang, Yi‐Ting;
    • Fernandez‐Arias, Jaime;
    • Stevenson, Alyssa;
    • Socualaya, Kely Quispialaya;
    • Haeger, Arlette;
    • Nazneen, Tahnia;
    • Aumont, Étienne;
    • Hosseini, Ali;
    • Rej, Soham;
    • Vitali, Paolo
    Publication type:
    Article

  • Preanalytical stability of plasma/serum brain‐derived tau.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 4764, doi. 10.1002/alz.13156
    By:
    • Gonzalez‐Ortiz, Fernando;
    • Dias, Alexandre;
    • Turton, Michael;
    • Magalhães, Rui;
    • Kac, Przemysław R.;
    • Correia, Manuel;
    • Harrison, Peter;
    • Zetterberg, Henrik;
    • Maia, Luís F.;
    • Blennow, Kaj;
    • Karikari, Thomas K.
    Publication type:
    Article

  • Longitudinal changes in Alzheimer's‐related plasma biomarkers and brain amyloid.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 4335, doi. 10.1002/alz.13157
    By:
    • Bilgel, Murat;
    • An, Yang;
    • Walker, Keenan A.;
    • Moghekar, Abhay R.;
    • Ashton, Nicholas J.;
    • Kac, Przemysław R.;
    • Karikari, Thomas K.;
    • Blennow, Kaj;
    • Zetterberg, Henrik;
    • Jedynak, Bruno M.;
    • Thambisetty, Madhav;
    • Ferrucci, Luigi;
    • Resnick, Susan M.
    Publication type:
    Article

  • Plasma biomarkers identify older adults at risk of Alzheimer's disease and related dementias in a real‐world population‐based cohort.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 4507, doi. 10.1002/alz.12986
    By:
    • Ferreira, Pamela C. L.;
    • Zhang, Yingjin;
    • Snitz, Beth;
    • Chang, Chung‐Chou H.;
    • Bellaver, Bruna;
    • Jacobsen, Erin;
    • Kamboh, M. Ilyas;
    • Zetterberg, Henrik;
    • Blennow, Kaj;
    • Pascoal, Tharick A.;
    • Villemagne, Victor L.;
    • Ganguli, Mary;
    • Karikari, Thomas K.
    Publication type:
    Article