Works by Karelson, Mati

Results: 36

A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00365

By:

Sidorova, Yulia A.;
Bespalov, Maxim M.;
Wong, Agnes W.;
Kambur, Oleg;
Jokinen, Viljami;
Lilius, Tuomas O.;
Suleymanova, Ilida;
Karelson, Gunnar;
Rauhala, Pekka V.;
Karelson, Mati;
Osborne, Peregrine B.;
Keast, Janet R.;
Kalso, Eija A.;
Saarma, Mart

Publication type:

Article

Topological Fingerprints as an Aid in Finding Structural Patterns for LRRK2 Inhibition.

Published in:

Molecular Informatics, 2014, v. 33, n. 4, p. 269, doi. 10.1002/minf.201300057

By:

Kahn, Iiris;
Lomaka, Andre;
Karelson, Mati

Publication type:

Article

Subchronic Oral and Inhalation Toxicities: a Challenging Attempt for Modeling and Prediction.

Published in:

Molecular Informatics, 2013, v. 32, n. 9/10, p. 793, doi. 10.1002/minf.201300033

By:

Dobchev, Dimaitar A.;
Tulp, Indrek;
Karelson, Gunnar;
Tamm, Tarmo;
Tämm, Kaido;
Karelson, Mati

Publication type:

Article

Glial cell line-derived neurotrophic factor receptor Rearranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo.

Published in:

2020

By:

Mahato, Arun Kumar;
Kopra, Jaakko;
Renko, Juho‐Matti;
Visnapuu, Tanel;
Korhonen, Ilari;
Pulkkinen, Nita;
Bespalov, Maxim M.;
Domanskyi, Andrii;
Ronken, Eric;
Piepponen, T. Petteri;
Voutilainen, Merja H.;
Tuominen, Raimo K.;
Karelson, Mati;
Sidorova, Yulia A.;
Saarma, Mart;
Renko, Juho-Matti

Publication type:

journal article

Dengue Virus Inhibitors as Potential Broad-Spectrum Flavivirus Inhibitors.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 3, p. 283, doi. 10.3390/ph18030283

By:

Ivanova, Larisa;
Naumenko, Krystyna;
Varjak, Margus;
Koit, Sandra;
Morozovsky, Yehudit;
Merits, Andres;
Karelson, Mati;
Zusinaite, Eva

Publication type:

Article

Refinement of a Quantitative Structure-Activity Relationship Model for Prediction of Cell-Penetrating Peptide Based Transfection Systems.

Published in:

International Journal of Peptide Research & Therapeutics, 2017, v. 23, n. 1, p. 91, doi. 10.1007/s10989-016-9542-8

By:

Dowaidar, Moataz;
Regberg, Jakob;
Dobchev, Dimitar;
Lehto, Tõnis;
Hällbrink, Mattias;
Karelson, Mati;
Langel, Ülo

Publication type:

Article

Epitranscriptomic regulation in fasting hearts: implications for cardiac health.

Published in:

RNA Biology, 2024, v. 21, n. 1, p. 290, doi. 10.1080/15476286.2024.2307732

By:

Benak, Daniel;
Holzerova, Kristyna;
Hrdlicka, Jaroslav;
Kolar, Frantisek;
Olsen, Mark;
Karelson, Mati;
Hlavackova, Marketa

Publication type:

Article

Structure-based calculation of drug efficiency indices.

Published in:

Bioinformatics, 2007, v. 23, n. 20, p. 2678, doi. 10.1093/bioinformatics/btm431

By:

Hetényi, Csaba;
Maran, Uko;
García-Sosa, Alfonso T.;
Karelson, Mati

Publication type:

Article

Reconsideration of solvent effects calculated by semiempirical quantum chemical methods.

Published in:

Journal of Computational Chemistry, 1993, v. 14, n. 3, p. 371, doi. 10.1002/jcc.540140312

By:

Szafran, Miroslaw;
Karelson, Mati M.;
Katritzky, Alan R.;
Koput, Jacek;
Zerner, Michael C.

Publication type:

Article

Small-Molecule Inhibitors of the RNA M6A Demethylases FTO Potently Support the Survival of Dopamine Neurons.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4537, doi. 10.3390/ijms22094537

By:

Selberg, Simona;
Yu, Li-Ying;
Bondarenko, Olesja;
Kankuri, Esko;
Seli, Neinar;
Kovaleva, Vera;
Herodes, Koit;
Saarma, Mart;
Karelson, Mati;
Svenningsson, Per

Publication type:

Article

QSPR modeling of UV absorption intensities.

Published in:

Journal of Computer-Aided Molecular Design, 2007, v. 21, n. 7, p. 371, doi. 10.1007/s10822-007-9118-y

By:

Katritzky, Alan;
Slavov, Svetoslav;
Dobchev, Dimitar;
Karelson, Mati

Publication type:

Article

Quantitative Structure-Activity Relationship (QSAR) Modeling of EC50 of Aquatic Toxicities for Daphnia magna.

Published in:

Journal of Toxicology & Environmental Health: Part A, 2009, v. 72, n. 19, p. 1181, doi. 10.1080/15287390903091863

By:

Katritzky, Alan R.;
Slavov, Svetoslav H.;
Stoyanova-Slavova, Iva S.;
Kahn, Iiris;
Karelson, Mati

Publication type:

Article

Electron impact mass spectrometric studies of 2-methyl, 2-phenyl, 2-(1-piperidyl), 2-(2/3/4-pyridyl), piperidino and pyrido[4,3-d]-pyrimidin-4-ones.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 1998, v. 12, n. 23, p. 1845, doi. 10.1002/(SICI)1097-0231(19981215)12:23<1845::AID-RCM404>3.0.CO;2-8

By:

Oksman, Pentti;
Pihlaja, Kalevi;
Fülöp, Ferenc;
Huber, Imre;
Bernáth, Gábor;
Karelson, Mati;
Perkson, Antti

Publication type:

Article

Quantitative structure-activity relationship modeling of bioconcentration factors of polychlorinated biphenyls.

Published in:

Toxicological & Environmental Chemistry, 2010, v. 92, n. 7, p. 1233, doi. 10.1080/02772240903306417

By:

Katritzky, Alan R.;
Radzvilovits, Maksim;
Slavov, Svetoslav;
Kasemets, Kalev;
Tamm, Kaido;
Karelson, Mati

Publication type:

Article

Reaction field effects on the electronic structure of carbon radical and ionic centers.

Published in:

International Journal of Quantum Chemistry, 1990, v. 37, n. 1, p. 1, doi. 10.1002/qua.560370102

By:

Karelson, Mati;
Tamm, Toomas;
Katritzky, Alan R.;
Szafran, Miroslaw;
Zerner, Michael C.

Publication type:

Article

Reaction field effects on the electron distribution and chemical reactivity of molecules.

Published in:

International Journal of Quantum Chemistry, 1986, v. 30, p. 521, doi. 10.1002/qua.560300745

By:

Karelson, Mati M.;
Katritzky, Alan R.;
Zerner, Michael C.

Publication type:

Article

QSAR study of pharmacological permeabilities.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2009, p. 218

By:

Karelson, Mati;
Karelson, Gunnar;
Tamm, Tarmo;
Indrek Tulp;
Jänes, Jaak;
Tämm, Kaido;
Lomaka, Andre;
Savchenko, Deniss;
Dobcheva, Dimitar

Publication type:

Article

Novel RET agonist for the treatment of experimental neuropathies.

Published in:

Molecular Pain, 2020, v. 16, p. 1, doi. 10.1177/1744806920950866

By:

Viisanen, Hanna;
Nuotio, Ulpukka;
Kambur, Oleg;
Mahato, Arun Kumar;
Jokinen, Viljami;
Lilius, Tuomas;
Li, Wei;
Santos, Hélder A;
Karelson, Mati;
Rauhala, Pekka;
Kalso, Eija;
Sidorova, Yulia A

Publication type:

Article

Novel RET agonist for the treatment of experimental neuropathies.

Published in:

Molecular Pain, 2020, p. 1, doi. 10.1177/1744806920950866

By:

Viisanen, Hanna;
Nuotio, Ulpukka;
Kambur, Oleg;
Mahato, Arun Kumar;
Jokinen, Viljami;
Lilius, Tuomas;
Li, Wei;
Santos, Hélder A;
Karelson, Mati;
Rauhala, Pekka;
Kalso, Eija;
Sidorova, Yulia A

Publication type:

Article

QSPR Modelling of Lanthanide‐Organic Complex Stability Constants.

Published in:

Separation Science & Technology, 2006, v. 41, n. 1, p. 197, doi. 10.1080/01496390500446194

By:

Svetlitski, Ruslan;
Lomaka, Andre;
Karelson, Mati

Publication type:

Article

Have artificial neural networks met expectations in drug discovery as implemented in QSAR framework?

Published in:

Expert Opinion on Drug Discovery, 2016, v. 11, n. 7, p. 627, doi. 10.1080/17460441.2016.1186876

By:

Dobchev, Dimitar;
Karelson, Mati

Publication type:

Article

RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128686

By:

Mutso, Margit;
Nikonov, Andrei;
Pihlak, Arno;
Žusinaite, Eva;
Viru, Liane;
Selyutina, Anastasia;
Reintamm, Tõnu;
Kelve, Merike;
Saarma, Mart;
Karelson, Mati;
Merits, Andres

Publication type:

Article

A quantum-mechanical study of oxidized oligopyrroles.

Published in:

International Journal of Quantum Chemistry, 1999, v. 71, n. 1, p. 101, doi. 10.1002/(SICI)1097-461X(1999)71:1<101::AID-QUA10>3.0.CO;2-Z

By:

Tamm, Tarmo;
Tamm, Jüri;
Karelson, Mati

Publication type:

Article

Theoretical study of aminoalkylation in the Mannich reaction of furan with methyleneimminium salt.

Published in:

International Journal of Quantum Chemistry, 1998, v. 67, n. 6, p. 359, doi. 10.1002/(SICI)1097-461X(1998)67:6<359::AID-QUA2>3.0.CO;2-U

By:

Maran, Uko;
Katritzky, Alan R.;
Karelson, Mati

Publication type:

Article

Quantum chemical modelling of the effect of proline residues on peptide conformation.

Published in:

International Journal of Quantum Chemistry, 1997, v. 66, n. 5, p. 391, doi. 10.1002/(SICI)1097-461X(1998)66:5<391::AID-QUA5>3.0.CO;2-Q

By:

Sak, Katrin;
Karelson, Mati;
Järv, Jaak

Publication type:

Article

A comparative AM1 and ab initio study of the intramolecular proton transfer in tautomeric organic compounds.

Published in:

International Journal of Quantum Chemistry, 1996, v. 60, n. 8, p. 1765, doi. 10.1002/(SICI)1097-461X(1996)60:8<1765::AID-QUA4>3.0.CO;2-W

By:

Maran, Uko;
Karelson, Mati;
Katritzky, Alan R.

Publication type:

Article

A semiempirical study of heterocycle oligomers and polymers in different dielectric media.

Published in:

International Journal of Quantum Chemistry, 1995, v. 54, n. 6, p. 369, doi. 10.1002/qua.560540606

By:

Jüuurimäaue, Tiit;
Strandberg, Marek;
Karelson, Mati;
Calais, Jean-Louis

Publication type:

Article

Multicavity SCRF calculation of ion hydration energies.

Published in:

International Journal of Quantum Chemistry, 1994, v. 52, p. 339, doi. 10.1002/qua.560520834

By:

Diercksen, Geerd H. F.;
Karelson, Mati;
Tamm, Toomas;
Zerner, Michael C.

Publication type:

Article

Inhibition of ALKBH5 demethylase of m<sup>6</sup>A pathway potentiates HIV-1 reactivation from latency.

Published in:

Virology Journal, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12985-025-02744-4

By:

Ali, Haider;
Wadas, Jakub;
Bendoumou, Maryam;
Chen, Heng-Chang;
Maiuri, Paolo;
Dutilleul, Antoine;
Selberg, Simona;
Nestola, Lorena;
Lalik, Kamil;
Avettand-Fenoël, Veronique;
Necsoi, Coca;
Marcello, Alessandro;
Kankuri, Esko;
Karelson, Mati;
De Wit, Stéphane;
Pyrc, Krzysztof;
Pasternak, Alexander O.;
Van Lint, Carine;
Kula-Pacurar, Anna

Publication type:

Article

The Impact of Software Used and the Type of Target Protein on Molecular Docking Accuracy.

Published in:

Molecules, 2022, v. 27, n. 24, p. 9041, doi. 10.3390/molecules27249041

By:

Ivanova, Larisa;
Karelson, Mati

Publication type:

Article

Multitarget Approach to Drug Candidates against Alzheimer's Disease Related to AChE, SERT, BACE1 and GSK3β Protein Targets.

Published in:

Molecules, 2020, v. 25, n. 8, p. 1846, doi. 10.3390/molecules25081846

By:

Ivanova, Larisa;
Karelson, Mati;
Dobchev, Dimitar A.;
Malawska, Barbara

Publication type:

Article

Identification of Natural Compounds against Neurodegenerative Diseases Using In Silico Techniques.

Published in:

Molecules, 2018, v. 23, n. 8, p. 1847, doi. 10.3390/molecules23081847

By:

Ivanova, Larisa;
Karelson, Mati;
Dobchev, Dimitar A.

Publication type:

Article

Nitrobenzene toxicity: QSAR correlations and mechanistic interpretations.

Published in:

Journal of Physical Organic Chemistry, 2003, v. 16, n. 10, p. 811, doi. 10.1002/poc.643

By:

Katritzky, Alan R.;
Oliferenko, Polina;
Oliferenko, Alexander;
Lomaka, Andre;
Karelson, Mati

Publication type:

Article

Prediction of liquid viscosity for organic compounds by a quantitative structure-property relationship.

Published in:

Journal of Physical Organic Chemistry, 2000, v. 13, n. 1, p. 80, doi. 10.1002/(SICI)1099-1395(200001)13:1<80::AID-POC179>3.0.CO;2-8

By:

Katritzky, Alan R.;
Chen, Ke;
Wang, Yilin;
Karelson, Mati;
Lucic, Bono;
Trinajstic, Nenad;
Suzuki, Takahiro;
Schüürmann, Gerrit

Publication type:

Article

Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats.

Published in:

Journal of Parkinson's Disease, 2021, v. 11, n. 3, p. 1023, doi. 10.3233/JPD-202400

By:

Renko, Juho-Matti;
Mahato, Arun Kumar;
Visnapuu, Tanel;
Valkonen, Konsta;
Karelson, Mati;
Voutilainen, Merja H.;
Saarma, Mart;
Tuominen, Raimo K.;
Sidorova, Yulia A.

Publication type:

Article

Theoretical study of the effect of counterions on the structure of pyrrole oligomers.

Published in:

International Journal of Quantum Chemistry, 2002, v. 88, n. 2, p. 296, doi. 10.1002/qua.10171

By:

Tamm, Tarmo;
Tamm, Jüri;
Karelson, Mati

Publication type:

Article