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Burosumab Treatment for Autosomal Recessive Hypophosphatemic Rickets Type 1 (ARHR1).
Published in:
Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 10, p. 2777, doi. 10.1210/clinem/dgac433
By:
- Xiuying Bai;
- Levental, Mark;
- Karaplis, Andrew C.
Publication type:
Article
PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target.
Published in:
2011
By:
- Jiarong Li;
- Karaplis, Andrew C.;
- Dao C. Huang;
- Siegel, Peter M.;
- Camirand, Anne;
- Xian Fang Yang;
- Muller, William J.;
- Kremer, Richard;
- Li, Jiarong;
- Huang, Dao C;
- Yang, Xian Fang
Publication type:
journal article
Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34.
Published in:
2005
By:
- Miao, Dengshun;
- He, Bin;
- Jiang, Yebin;
- Kobayashi, Tatsuya;
- Sorocéanu, Maria A;
- Zhao, Jenny;
- Su, Hanyi;
- Tong, Xinkang;
- Amizuka, Norio;
- Gupta, Ajay;
- Genant, Harry K;
- Kronenberg, Henry M;
- Goltzman, David;
- Karaplis, Andrew C
Publication type:
journal article
Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34.
Published in:
Journal of Clinical Investigation, 2005, v. 115, n. 9, p. 2402, doi. 10.1172/JCI24918
By:
- Dengshun Miao;
- Bin He;
- Yebin Jiang;
- Kobayashi, Tatsuya;
- Sorocéanu, Maria A.;
- Jenny Zhao;
- Hanyi Su;
- Xinkang Tong;
- Amizuka, Norio;
- Gupta, Ajay;
- Genant, Harry K.;
- Kronenberg, Henry M.;
- Goltzman, David;
- Karaplis, Andrew C.
Publication type:
Article
Role of Parathyroid Hormone-Related Protein in Skeletal Development.
Published in:
Annals of the New York Academy of Sciences, 1996, v. 785, n. 1, p. 119, doi. 10.1111/j.1749-6632.1996.tb56249.x
By:
- Kronenberg, Henry M.;
- Karaplis, Andrew C.;
- Lanske, Beate
Publication type:
Article
Parathyroid hormone-related protein and its receptors: nuclear functions and roles in the renal and cardiovascular systems, the placental trophoblasts and the pancreatic islets.
Published in:
British Journal of Pharmacology, 2001, v. 134, n. 6, p. 1113, doi. 10.1038/sj.bjp.0704378
By:
- Clemens, Thomas L;
- Cormier, Sarah;
- Eichinger, Anne;
- Endlich, Karlhans;
- Fiaschi-Taesch, Nathalie;
- Fischer, Evelyne;
- Friedman, Peter A;
- Karaplis, Andrew C;
- Massfelder, Thierry;
- Rossert, Jérôme;
- Schlüter, Klaus-Dieter;
- Silve, Caroline;
- Stewart, Andrew F;
- Takane, Karen;
- Helwig, Jean-Jacques
Publication type:
Article
Upregulation of calcitriol during pregnancy and skeletal recovery after lactation do not require parathyroid hormone.
Published in:
Journal of Bone & Mineral Research, 2013, v. 28, n. 9, p. 1987, doi. 10.1002/jbmr.1925
By:
- Kirby, Beth J;
- Ma, Yue;
- Martin, Heather M;
- Buckle Favaro, Kerri L;
- Karaplis, Andrew C;
- Kovacs, Christopher S
Publication type:
Article
Skeletal recovery after weaning does not require PTHrP.
Published in:
Journal of Bone & Mineral Research, 2011, v. 26, n. 6, p. 1242, doi. 10.1002/jbmr.339
By:
- Kirby, Beth J.;
- Ardeshirpour, Laleh;
- Woodrow, Janine P.;
- Wysolmerski, John J.;
- Sims, Natalie A.;
- Karaplis, Andrew C.;
- Kovacs, Christopher S.
Publication type:
Article
Parathyroid Hormone Regulates Fetal-Placental Mineral Homeostasis.
Published in:
Journal of Bone & Mineral Research, 2010, v. 25, n. 3, p. 594, doi. 10.1359/jbmr.090825
By:
- Simmonds, Charlene S.;
- Karsenty, Gerard;
- Karaplis, Andrew C.;
- Kovacs, Christopher S.
Publication type:
Article
Exogenous PTH-Related Protein and PTH Improve Mineral and Skeletal Status in 25-Hydroxyvitamin D-1α-Hydroxylase and PTH Double Knockout Mice.
Published in:
Journal of Bone & Mineral Research, 2005, v. 20, n. 10, p. 1766, doi. 10.1359/JBMR.050608
By:
- Xue, Yingben;
- Zhang, Zengli;
- Karaplis, Andrew C;
- Hendy, Geoffrey N;
- Goltzman, David;
- Miao, Dengshun
Publication type:
Article
Tumor-Induced Osteomalacia: Clinical and Basic Studies.
Published in:
Journal of Bone & Mineral Research, 1997, v. 12, n. 9, p. 1502, doi. 10.1359/jbmr.1997.12.9.1502
By:
- Shane, Elizabeth;
- Parisien, May;
- Henderson, Janet E.;
- Dempster, David W.;
- Feldman, Frieda;
- Hardy, Mark A.;
- Tohme, Jack F.;
- Karaplis, Andrew C.;
- Clemens, Thomas L.
Publication type:
Article
Interaction of nascent preproparathyroid hormone molecules with microsomal membranes.
Published in:
Journal of Bone & Mineral Research, 1992, v. 7, n. 2, p. 199, doi. 10.1002/jbmr.5650070211
By:
- Baba, Hisamitsu;
- Karaplis, Andrew C.;
- Wiren, Kristine M.;
- Keutmann, Henry T.;
- Kronenberg, Henry M.
Publication type:
Article
Fibroblast growth factor 23 overexpression impacts negatively on dentin mineralization and dentinogenesis in mice.
Published in:
Clinical & Experimental Pharmacology & Physiology, 2011, v. 38, n. 6, p. 395, doi. 10.1111/j.1440-1681.2011.05526.x
By:
- Chen, Ling;
- Liu, Hong;
- Sun, Wen;
- Bai, Xiuying;
- Karaplis, Andrew C;
- Goltzman, David;
- Miao, Dengshun
Publication type:
Article
A Case of Male Osteoporosis: A 37-Year-Old Man with Multiple Vertebral Compression Fractures.
Published in:
2017
By:
- Radi, Suhaib;
- Karaplis, Andrew C.
Publication type:
Case Study
The nucleus: A target site for parathyroid hormone-related peptide (PTHrP) action.
Published in:
Journal of Cellular Biochemistry, 1998, v. 70, n. 2, p. 193, doi. 10.1002/(SICI)1097-4644(19980801)70:2<193::AID-JCB5>3.0.CO;2-J
By:
- Nguyen, M.T. Audrey;
- Karaplis, Andrew C.
Publication type:
Article
PTHrP Regulates Fatty Acid Metabolism via Novel lncRNA in Breast Cancer Initiation and Progression Models.
Published in:
Cancers, 2023, v. 15, n. 15, p. 3763, doi. 10.3390/cancers15153763
By:
- Zhang, Rui;
- Li, Jiarong;
- Badescu, Dunarel;
- Karaplis, Andrew C.;
- Ragoussis, Jiannis;
- Kremer, Richard
Publication type:
Article
Molecular basis of the spectrum of skeletal complications of neoplasia.
Published in:
Cancer (0008543X), 2000, v. 88, n. S12, p. 2903, doi. 10.1002/1097-0142(20000615)88:12+<2903::AID-CNCR4>3.0.CO;2-G
By:
- Goltzman, David;
- Karaplis, Andrew C.;
- Kremer, Richard;
- Rabbani, Shafaat A.
Publication type:
Article
CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders.
Published in:
2016
By:
- Xiuying Bai;
- Dengshun Miao;
- Sophia Xiao;
- Dinghong Qiu;
- St-Arnaud, René;
- Petkovich, Martin;
- Gupta, Ajay;
- Goltzman, David;
- Karaplis, Andrew C.;
- Bai, Xiuying;
- Miao, Dengshun;
- Xiao, Sophia;
- Qiu, Dinghong
Publication type:
journal article
Constitutive expression of parathyroid hormone-related peptide PTHnP stimulates growth and inhibits differentiation of CFK2 chondrocytes.
Published in:
Journal of Cellular Physiology, 1996, v. 169, n. 1, p. 33, doi. 10.1002/(SICI)1097-4652(199610)169:1<33::AID-JCP4>3.0.CO;2-F
By:
- Henderson, Janet E.;
- He, Bin;
- Goltzman, David;
- Karaplis, Andrew C.
Publication type:
Article
Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development.
Published in:
Human Molecular Genetics, 2005, v. 14, n. 11, p. 1515, doi. 10.1093/hmg/ddi160
By:
- Xue, Yingben;
- Karaplis, Andrew C.;
- Hendy, Geoffrey N.;
- Goltzman, David;
- Miao, Dengshun
Publication type:
Article
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition.
Published in:
Human Molecular Genetics, 2001, v. 10, n. 5, p. 433, doi. 10.1093/hmg/10.5.433
By:
- Chen, Zhoutao;
- Karaplis, Andrew C.;
- Ackerman, Susan L.;
- Pogribny, Igor P.;
- Melnyk, Stepan;
- Lussier-Cacan, Suzanne;
- Chen, Moy Fong;
- Pai, Aditya;
- John, Simon W.M.;
- Smith, Richard S.;
- Bottiglieri, Teodoro;
- Bagley, Pamela;
- Selhub, Jacob;
- Rudnicki, Michael A.;
- James, S. Jill;
- Rozen, Rima
Publication type:
Article
Role of PTHrP nuclear localization and carboxyl terminus sequences in postnatal spinal cord development.
Published in:
Developmental Neurobiology (19328451), 2021, v. 81, n. 1, p. 47, doi. 10.1002/dneu.22798
By:
- Liu, Yahong;
- Wang, Qiangcheng;
- Wang, Qun;
- Cui, Min;
- Jin, Yaoyao;
- Wang, Rong;
- Mao, Zhiyuan;
- Miao, Dengshun;
- Karaplis, Andrew C.;
- Zhang, Yi Ping;
- Shields, Lisa B. E.;
- Shields, Christopher B.;
- Zhang, Yongjie
Publication type:
Article
Vitamin D status and response to daily 400 IU vitamin D3 and weekly alendronate 70 mg in men and women with osteoporosis.
Published in:
2011
By:
- Karaplis AC;
- Chouha F;
- Djandji M;
- Sampalis JS;
- Hanley DA;
- Karaplis, Andrew C;
- Chouha, Fridon;
- Djandji, Michel;
- Sampalis, John S;
- Hanley, David A
Publication type:
journal article
Vitamin D Status and Response to Daily 400 IU Vitamin D<sub>3</sub> and Weekly Alendronate 70 mg in Men and Women with Osteoporosis.
Published in:
Annals of Pharmacotherapy, 2011, v. 45, n. 5, p. 561, doi. 10.1345/aph.1P439
By:
- Karaplis, Andrew C.;
- Chouha, Fridon;
- Djandji, Michel;
- Sampalis, John S.;
- Hanley, David A.
Publication type:
Article
Exogenous PTH‐Related Protein and PTH Improve Mineral and Skeletal Status in 25‐Hydroxyvitamin D‐1α‐Hydroxylase and PTH Double Knockout Mice.
Published in:
2020
By:
- Xue, Yingben;
- Zhang, Zengli;
- Karaplis, Andrew C;
- Hendy, Geoffrey N;
- Goltzman, and, David;
- Miao, Dengshun
Publication type:
Correction Notice
Metabolic bone disease: Lessons from knockout mice.
Published in:
Drug Development Research, 2000, v. 49, n. 3, p. 159, doi. 10.1002/(SICI)1098-2299(200003)49:3<159::AID-DDR6>3.0.CO;2-L
By:
- Karaplis, Andrew C.
Publication type:
Article

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