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Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.19406
By:
- Stillitano, Francesca;
- Hansen, Jens;
- Chi-Wing Kong;
- Karakikes, Ioannis;
- Funck-Brentano, Christian;
- Lin Geng;
- Scott, Stuart;
- Reynier, Stephan;
- Ma Wu;
- Valogne, Yannick;
- Desseaux, Carole;
- Salem, Joe-Elie;
- Jeziorowska, Dorota;
- Zahr, Noël;
- Ronald Li;
- Iyengar, Ravi;
- Hajjar, Roger J.;
- Hulot, Jean-Sébastien
Publication type:
Article
Concise Review: Precision Matchmaking: Induced Pluripotent Stem Cells Meet Cardio‐Oncology.
Published in:
Stem Cells Translational Medicine, 2019, v. 8, n. 8, p. 758, doi. 10.1002/sctm.18-0279
By:
- Nair, Pooja;
- Prado, Maricela;
- Perea‐Gil, Isaac;
- Karakikes, Ioannis
Publication type:
Article
Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094231
By:
- Durruthy-Durruthy, Jens;
- Briggs, Sharon F.;
- Awe, Jason;
- Ramathal, Cyril Y.;
- Karumbayaram, Saravanan;
- Lee, Patrick C.;
- Heidmann, Julia D.;
- Clark, Amander;
- Karakikes, Ioannis;
- Loh, Kyle M.;
- Wu, Joseph C.;
- Hoffman, Andrew R.;
- Byrne, James;
- Reijo Pera, Renee A.;
- Sebastiano, Vittorio
Publication type:
Article
Active Inhibitor-1 Maintains Protein Hyper-Phosphorylation in Aging Hearts and Halts Remodeling in Failing Hearts.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0080717
By:
- Pritchard, Tracy J.;
- Kawase, Yoshiaki;
- Haghighi, Kobra;
- Anjak, Ahmad;
- Cai, Wenfeng;
- Jiang, Min;
- Nicolaou, Persoulla;
- Pylar, George;
- Karakikes, Ioannis;
- Rapti, Kleopatra;
- Rubinstein, Jack;
- Hajjar, Roger J.;
- Kranias, Evangelia G.
Publication type:
Article
Gene Remodeling in Type 2 Diabetic Cardiomyopathy and Its Phenotypic Rescue with SERCA2a.
Published in:
PLoS ONE, 2009, v. 4, n. 7, p. 1, doi. 10.1371/journal.pone.0006474
By:
- Karakikes, Ioannis;
- Kim, Maengjo;
- Hadri, Lahouaria;
- Sakata, Susumu;
- Yezhou Sun;
- Weijia Zhang;
- Chemaly, Elie R.;
- Hajjar, Roger J.;
- Lebeche, Djamel
Publication type:
Article
How efficiently educational programs prepare professionals to meet current and future challenges of transport interchanges.
Published in:
European Transport: International Journal of Transport Economics, Engineering & Law, 2020, n. 79, p. 1, doi. 10.48295/et.2020.79.10
By:
- Nathanail, Eftihia;
- Adamos, Giannis;
- Mitropoulos, Lambros;
- Karakikes, Ioannis;
- Yatskiv (Jackiva), Irina
Publication type:
Article
A Novel Recessive Mutation in SPEG Causes Early Onset Dilated Cardiomyopathy.
Published in:
PLoS Genetics, 2020, v. 16, n. 9, p. 1, doi. 10.1371/journal.pgen.1009000
By:
- Levitas, Aviva;
- Muhammad, Emad;
- Zhang, Yuan;
- Perea Gil, Isaac;
- Serrano, Ricardo;
- Diaz, Nashielli;
- Arafat, Maram;
- Gavidia, Alexandra A.;
- Kapiloff, Michael S.;
- Mercola, Mark;
- Etzion, Yoram;
- Parvari, Ruti;
- Karakikes, Ioannis
Publication type:
Article
Small Molecule-Mediated Directed Differentiation of Human Embryonic Stem Cells Toward Ventricular Cardiomyocytes.
Published in:
Stem Cells Translational Medicine, 2014, v. 3, n. 1, p. 18, doi. 10.5966/sctm.2013-0110
By:
- KARAKIKES, IOANNIS;
- SENYEI, GRANT D.;
- HANSEN, JENS;
- CHI-WING KONG;
- AZELOGLU, EVREN U.;
- STILLITANO, FRANCESCA;
- LIEU, DEBORAH K.;
- JIAXIAN WANG;
- LIHUAN REN;
- HULOT, JEAN-SEBASTIEN;
- IYENGAR, RAVI;
- LI, RONALD A.;
- HAJJAR, ROGER J.
Publication type:
Article
Concise Review: Mending a Broken Heart: The Evolution of Biological Therapeutics.
Published in:
Stem Cells, 2017, v. 35, n. 5, p. 1131, doi. 10.1002/stem.2602
By:
- Chen, Caressa;
- Termglinchan, Vittavat;
- Karakikes, Ioannis
Publication type:
Article
Shrink-Film Configurable Multiscale Wrinkles for Functional Alignment of Human Embryonic Stem Cells and their Cardiac Derivatives.
Published in:
Advanced Materials, 2011, v. 23, n. 48, p. 5785, doi. 10.1002/adma.201103463
By:
- Chen, Aaron;
- Lieu, Deborah K.;
- Freschauf, Lauren;
- Lew, Valerie;
- Sharma, Himanshu;
- Wang, Jiaxian;
- Nguyen, Diep;
- Karakikes, Ioannis;
- Hajjar, Roger J.;
- Gopinathan, Ajay;
- Botvinick, Elliot;
- Fowlkes, Charless C.;
- Li, Ronald A.;
- Khine, Michelle
Publication type:
Article
Cardiac I-1c Overexpression With Reengineered AAV Improves Cardiac Function in Swine Ischemic Heart Failure.
Published in:
Molecular Therapy, 2014, v. 22, n. 12, p. 2038, doi. 10.1038/mt.2014.127
By:
- Ishikawa, Kiyotake;
- Fish, Kenneth M;
- Tilemann, Lisa;
- Rapti, Kleopatra;
- Aguero, Jaume;
- Santos-Gallego, Carlos G;
- Lee, Ahyoung;
- Karakikes, Ioannis;
- Xie, Chaoqin;
- Akar, Fadi G;
- Shimada, Yuichi J;
- Gwathmey, Judith K;
- Asokan, Aravind;
- McPhee, Scott;
- Samulski, Jade;
- Samulski, Richard Jude;
- Sigg, Daniel C;
- Weber, Thomas;
- Kranias, Evangelia G;
- Hajjar, Roger J
Publication type:
Article
AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes.
Published in:
PLoS ONE, 2019, v. 14, n. 12, p. N.PAG, doi. 10.1371/journal.pone.0226694
By:
- Bruyneel, Arne A. N.;
- Colas, Alexandre R.;
- Karakikes, Ioannis;
- Mercola, Mark
Publication type:
Article
Recent Progress in Genome Editing Approaches for Inherited Cardiovascular Diseases.
Published in:
Current Cardiology Reports, 2018, v. 20, n. 7, p. 1, doi. 10.1007/s11886-018-0998-3
By:
- Kaur, Balpreet;
- Perea-Gil, Isaac;
- Karakikes, Ioannis
Publication type:
Article
Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium.
Published in:
FASEB Journal, 2014, v. 28, n. 2, p. 644, doi. 10.1096/fj.13-228007
By:
- Turnbull, Irene C.;
- Karakikes, Ioannis;
- Serrao, Gregory W.;
- Backeris, Peter;
- Jia-Jye Lee;
- Chaoqin Xie;
- Senyei, Grant;
- Gordon, Ronald E.;
- Li, Ronald A.;
- Akar, Fadi G.;
- Hajjar, Roger J.;
- Hulot, Jean-Sébastien;
- Costa, Kevin D.
Publication type:
Article
Interaction of HLA-DR and CD74 at the cell surface of antigen-presenting cells by single particle image analysis.
Published in:
FASEB Journal, 2012, v. 26, n. 12, p. 4886, doi. 10.1096/fj.12-211466
By:
- Karakikes, Ioannis;
- Morrison, Ian E. G.;
- O'Toole, Peter;
- Metodieva, Gergana;
- Navarrete, Cristina V.;
- Gomez, Jesus;
- Miranda-Sayago, Jose M.;
- Cherry, Richard J.;
- Metodiev, Metodi;
- Fernandez, Nelson
Publication type:
Article
Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy.
Published in:
Nature Communications, 2015, v. 6, n. 4, p. 6955, doi. 10.1038/ncomms7955
By:
- Karakikes, Ioannis;
- Stillitano, Francesca;
- Nonnenmacher, Mathieu;
- Tzimas, Christos;
- Sanoudou, Despina;
- Termglinchan, Vittavat;
- Kong, Chi-Wing;
- Rushing, Stephanie;
- Hansen, Jens;
- Ceholski, Delaine;
- Kolokathis, Fotis;
- Kremastinos, Dimitrios;
- Katoulis, Alexandros;
- Ren, Lihuan;
- Cohen, Ninette;
- Gho, Johannes M.I.H.;
- Tsiapras, Dimitrios;
- Vink, Aryan;
- Wu, Joseph C.;
- Asselbergs, Folkert W.
Publication type:
Article
De novo and inherited variants in coding and regulatory regions in genetic cardiomyopathies.
Published in:
Human Genomics, 2022, v. 16, n. 1, p. 1, doi. 10.1186/s40246-022-00420-0
By:
- Vadgama, Nirmal;
- Ameen, Mohamed;
- Sundaram, Laksshman;
- Gaddam, Sadhana;
- Gifford, Casey;
- Nasir, Jamal;
- Karakikes, Ioannis
Publication type:
Article
Mode Choice Modeling for Sustainable Last-Mile Delivery: The Greek Perspective.
Published in:
Sustainability (2071-1050), 2022, v. 14, n. 15, p. 8976, doi. 10.3390/su14158976
By:
- Polydoropoulou, Amalia;
- Tsirimpa, Athena;
- Karakikes, Ioannis;
- Tsouros, Ioannis;
- Pagoni, Ioanna
Publication type:
Article
Treatment of volumetric muscle loss in mice using nanofibrillar scaffolds enhances vascular organization and integration.
Published in:
Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0416-4
By:
- Nakayama, Karina H.;
- Quarta, Marco;
- Paine, Patrick;
- Alcazar, Cynthia;
- Karakikes, Ioannis;
- Garcia, Victor;
- Abilez, Oscar J.;
- Calvo, Nicholas S.;
- Simmons, Chelsey S.;
- Rando, Thomas A.;
- Huang, Ngan F.
Publication type:
Article
Concomitant Intravenous Nitroglycerin With Intracoronary Delivery of AAV1.SERCA2a Enhances Gene Transfer in Porcine Hearts.
Published in:
Molecular Therapy, 2012, v. 20, n. 3, p. 565, doi. 10.1038/mt.2011.268
By:
- Karakikes, Ioannis;
- Hadri, Lahouaria;
- Rapti, Kleopatra;
- Ladage, Dennis;
- Ishikawa, Kiyotake;
- Tilemann, Lisa;
- Yi, Geng-Hua;
- Morel, Charlotte;
- Gwathmey, Judith K;
- Zsebo, Krisztina;
- Weber, Thomas;
- Kawase, Yoshiaki;
- Hajjar, Roger J
Publication type:
Article
SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic Backgrounds.
Published in:
Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.888025
By:
- Vadgama, Nirmal;
- Kreymerman, Alexander;
- Campbell, Jackie;
- Shamardina, Olga;
- Brugger, Christiane;
- Research Consortium, Genomics England;
- Deaconescu, Alexandra M.;
- Lee, Richard T.;
- Penkett, Christopher J.;
- Gifford, Casey A.;
- Mercola, Mark;
- Nasir, Jamal;
- Karakikes, Ioannis
Publication type:
Article
Genomic correction of familial cardiomyopathy in human engineered cardiac tissues.
Published in:
European Heart Journal, 2016, v. 37, n. 43, p. 3282, doi. 10.1093/eurheartj/ehw307
By:
- Stillitano, Francesca;
- Turnbull, Irene C.;
- Karakikes, Ioannis;
- Nonnenmacher, Mathieu;
- Backeris, Peter;
- Hulot, Jean-Sébastien;
- Kranias, Evangelia G.;
- Hajjar, Roger J.;
- Costa, Kevin D.
Publication type:
Article

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