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Clinicopathological correlations in behavioural variant frontotemporal dementia.
Published in:
2017
By:
- Perry, David C.;
- Brown, Jesse A.;
- Possin, Katherine L.;
- Datta, Samir;
- Trujillo, Andrew;
- Radke, Anneliese;
- Karydas, Anna;
- Kornak, John;
- Sias, Ana C.;
- Rabinovici, Gil D.;
- Gorno-Tempini, Maria Luisa;
- Boxer, Adam L.;
- De May, Mary;
- Rankin, Katherine P.;
- Sturm, Virginia E.;
- Lee, Suzee E.;
- Matthews, Brandy R.;
- Kao, Aimee W.;
- Vossel, Keith A.;
- Tartaglia, Maria Carmela
Publication type:
journal article
Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.
Published in:
PLoS Genetics, 2019, v. 15, n. 8, p. 1, doi. 10.1371/journal.pgen.1008295
By:
- Butler, Victoria J.;
- Gao, Fuying;
- Corrales, Christian I.;
- Cortopassi, Wilian A.;
- Caballero, Benjamin;
- Vohra, Mihir;
- Ashrafi, Kaveh;
- Cuervo, Ana Maria;
- Jacobson, Matthew P.;
- Coppola, Giovanni;
- Kao, Aimee W.
Publication type:
Article
The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: The next therapeutic frontier)
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2013, v. 9, n. 2, p. 189, doi. 10.1016/j.jalz.2012.03.003
By:
- Boxer, Adam L.;
- Gold, Michael;
- Huey, Edward;
- Hu, William T.;
- Rosen, Howard;
- Kramer, Joel;
- Gao, Fen-Biao;
- Burton, Edward A.;
- Chow, Tiffany;
- Kao, Aimee;
- Leavitt, Blair R.;
- Lamb, Bruce;
- Grether, Megan;
- Knopman, David;
- Cairns, Nigel J.;
- Mackenzie, Ian R.;
- Mitic, Laura;
- Roberson, Erik D.;
- Van Kammen, Daniel;
- Cantillon, Marc
Publication type:
Article
Frontotemporal degeneration, the next therapeutic frontier: Molecules and animal models for frontotemporal degeneration drug development
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2013, v. 9, n. 2, p. 176, doi. 10.1016/j.jalz.2012.03.002
By:
- Boxer, Adam L.;
- Gold, Michael;
- Huey, Edward;
- Gao, Fen-Biao;
- Burton, Edward A.;
- Chow, Tiffany;
- Kao, Aimee;
- Leavitt, Blair R.;
- Lamb, Bruce;
- Grether, Megan;
- Knopman, David;
- Cairns, Nigel J.;
- Mackenzie, Ian R.;
- Mitic, Laura;
- Roberson, Erik D.;
- Van Kammen, Daniel;
- Cantillon, Marc;
- Zahs, Kathleen;
- Salloway, Stephen;
- Morris, John
Publication type:
Article
Progranulin Adsorbs to Polypropylene Tubes and Disrupts Functional Assays: Implications for Research, Biomarker Studies, and Therapeutics.
Published in:
Frontiers in Neuroscience, 2020, v. 11, p. N.PAG, doi. 10.3389/fnins.2020.602235
By:
- Gururaj, Sushmitha;
- Sampognaro, Paul J.;
- Argouarch, Andrea R.;
- Kao, Aimee W.
Publication type:
Article
Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia.
Published in:
JAMA Neurology, 2020, v. 77, n. 3, p. 358, doi. 10.1001/jamaneurol.2019.4284
By:
- Liu, Andy J.;
- Staffaroni, Adam M.;
- Rojas-Martinez, Julio C.;
- Olney, Nicholas T.;
- Alquezar-Burillo, Carolina;
- Ljubenkov, Peter A.;
- La Joie, Renaud;
- Fong, Jamie C.;
- Taylor, Joanne;
- Karydas, Anna;
- Ramos, Eliana Marisa;
- Coppola, Giovanni;
- Boxer, Adam L.;
- Rabinovici, Gil D.;
- Miller, Bruce L.;
- Kao, Aimee W.
Publication type:
Article
The effect of renal denervation in an experimental model of chronic renal insufficiency, The REmnant kidney Denervation In Pigs study (REDIP study).
Published in:
2017
By:
- Lubanda, Jean-Claude;
- Chochola, Miroslav;
- Mlček, Mikuláš;
- Neužil, Petr;
- Marek, Josef;
- Havránek, Štĕpán;
- Kuchynková, Sylvie;
- Fingrová, Zdeňka;
- Huang, Kao-Hsuan Aimee;
- Linhart, Aleš;
- Havránek, Štěpán
Publication type:
journal article
The progranulin cleavage product granulin 3 exerts a dominant negative effect on animal fitness.
Published in:
Human Molecular Genetics, 2024, v. 33, n. 3, p. 245, doi. 10.1093/hmg/ddad184
By:
- Wang, Austin L;
- Mambou, Edwina A;
- Kao, Aimee W
Publication type:
Article
Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport.
Published in:
Human Molecular Genetics, 2019, v. 28, n. 9, p. 1498, doi. 10.1093/hmg/ddy442
By:
- Butler, Victoria J;
- Salazar, Dominique A;
- Soriano-Castell, David;
- Alves-Ferreira, Miguel;
- Dennissen, Frank J A;
- Vohra, Mihir;
- Oses-Prieto, Juan A;
- Li, Kathy H;
- Wang, Austin L;
- Jing, Beibei;
- Li, Biao;
- Groisman, Alex;
- Gutierrez, Edgar;
- Mooney, Sean;
- Burlingame, Alma L;
- Ashrafi, Kaveh;
- Mandelkow, Eva-Maria;
- Encalada, Sandra E;
- Kao, Aimee W
Publication type:
Article
Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress.
Published in:
Human Molecular Genetics, 2018, v. 27, n. 22, p. 3951, doi. 10.1093/hmg/ddy297
By:
- Yuan, Shauna H;
- Hiramatsu, Nobuhiko;
- Liu, Qing;
- Sun, Xuehan Victoria;
- Lenh, David;
- Chan, Priscilla;
- Chiang, Karen;
- Koo, Edward H;
- Kao, Aimee W;
- Litvan, Irene
Publication type:
Article
Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation.
Published in:
Frontiers in Neurology, 2021, v. 11, p. N.PAG, doi. 10.3389/fneur.2020.595532
By:
- Alquezar, Carolina;
- Arya, Shruti;
- Kao, Aimee W.
Publication type:
Article
Tuberous sclerosis complex is associated with a novel human tauopathy.
Published in:
Acta Neuropathologica, 2023, v. 145, n. 1, p. 1, doi. 10.1007/s00401-022-02521-5
By:
- Hwang, Ji-Hye L.;
- Perloff, Olga S.;
- Gaus, Stephanie E.;
- Benitez, Camila;
- Alquezar, Carolina;
- Cosme, Celica Q.;
- Nana, Alissa L.;
- Vatsavayai, Sarat C.;
- Ramos, Eliana M.;
- Geschwind, Daniel H.;
- Miller, Bruce L.;
- Kao, Aimee W.;
- Seeley, William W.
Publication type:
Article
Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia.
Published in:
2017
By:
- Olney, Nicholas;
- Alquezar, Carolina;
- Ramos, Eliana;
- Nana, Alissa;
- Fong, Jamie;
- Karydas, Anna;
- Taylor, Joanne;
- Stephens, Melanie;
- Argouarch, Andrea;
- Berlo, Victoria;
- Dokuru, Deepika;
- Sherr, Elliott;
- Jicha, Gregory;
- Dillon, William;
- Desikan, Rahul;
- May, Mary;
- Seeley, William;
- Coppola, Giovanni;
- Miller, Bruce;
- Kao, Aimee
Publication type:
Letter
A Shift to Organismal Stress Resistance in Programmed Cell Death Mutants.
Published in:
PLoS Genetics, 2013, v. 9, n. 9, p. 1, doi. 10.1371/journal.pgen.1003714
By:
- Judy, Meredith E.;
- Nakamura, Ayumi;
- Huang, Anne;
- Grant, Harli;
- McCurdy, Helen;
- Weiberth, Kurt F.;
- Gao, Fuying;
- Coppola, Giovanni;
- Kenyon, Cynthia;
- Kao, Aimee W.
Publication type:
Article
Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31075-4
By:
- Li, Yi;
- Barkovich, Matthew J.;
- Karch, Celeste M.;
- Nillo, Ryan M.;
- Fan, Chun-Chieh;
- Broce, Iris J.;
- Tan, Chin Hong;
- Cuneo, Daniel;
- Hess, Christopher P.;
- Dillon, William P.;
- Glenn, Orit A.;
- Glastonbury, Christine M.;
- Olney, Nicholas;
- Yokoyama, Jennifer S.;
- Bonham, Luke W.;
- Miller, Bruce;
- Kao, Aimee;
- Schmansky, Nicholas;
- Fischl, Bruce;
- Andreassen, Ole A.
Publication type:
Article
Correction: Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases.
Published in:
2023
By:
- Sampognaro, Paul J.;
- Arya, Shruti;
- Knudsen, Giselle M.;
- Gunderson, Emma L.;
- Sandoval-Perez, Angelica;
- Hodul, Molly;
- Bowles, Kathryn;
- Craik, Charles S.;
- Jacobson, Matthew P.;
- Kao, Aimee W.
Publication type:
Correction Notice
Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases.
Published in:
Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00621-8
By:
- Sampognaro, Paul J.;
- Arya, Shruti;
- Knudsen, Giselle M.;
- Gunderson, Emma L.;
- Sandoval-Perez, Angelica;
- Hodul, Molly;
- Bowles, Katherine;
- Craik, Charles S.;
- Jacobson, Matthew P.;
- Kao, Aimee W.
Publication type:
Article
Protons in small spaces: Discrete simulations of vesicle acidification.
Published in:
PLoS Computational Biology, 2019, v. 15, n. 12, p. N.PAG, doi. 10.1371/journal.pcbi.1007539
By:
- Singh, Apeksha;
- Marcoline, Frank V.;
- Veshaguri, Salome;
- Kao, Aimee W.;
- Bruchez, Marcel;
- Mindell, Joseph A.;
- Stamou, Dimitrios;
- Grabe, Michael
Publication type:
Article
Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration.
Published in:
Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00472-1
By:
- Mohan, Swetha;
- Sampognaro, Paul J.;
- Argouarch, Andrea R.;
- Maynard, Jason C.;
- Welch, Mackenzie;
- Patwardhan, Anand;
- Courtney, Emma C.;
- Zhang, Jiasheng;
- Mason, Amanda;
- Li, Kathy H.;
- Huang, Eric J.;
- Seeley, William W.;
- Miller, Bruce L.;
- Burlingame, Alma;
- Jacobson, Mathew P.;
- Kao, Aimee W.
Publication type:
Article
The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels.
Published in:
Journal of Neuroscience, 2015, v. 35, n. 25, p. 9315, doi. 10.1523/JNEUROSCI.4808-14.2015
By:
- Salazar, Dominique A.;
- Butler, Victoria J.;
- Argouarch, Andrea R.;
- Tsung-Yuan Hsu;
- Mason, Amanda;
- Ayumi Nakamura;
- McCurdy, Helen;
- Cox, David;
- Ng, Rachel;
- Pan, Gloria;
- Seeley, William W.;
- Miller, Bruce L.;
- Kao, Aimee W.
Publication type:
Article
mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes.
Published in:
Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03165-w
By:
- Leng, Kun;
- Rooney, Brendan;
- McCarthy, Frank;
- Xia, Wenlong;
- Rose, Indigo V. L.;
- Bax, Sophie;
- Chin, Marcus;
- Fathi, Saeed;
- Herrington, Kari A.;
- Leonetti, Manuel;
- Kao, Aimee;
- Fancy, Stephen P. J.;
- Elias, Joshua E.;
- Kampmann, Martin
Publication type:
Article

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