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Cobinamide is effective for treatment of hydrogen sulfide-induced neurological sequelae in a mouse model.
- Published in:
- Annals of the New York Academy of Sciences, 2017, v. 1408, n. 1, p. 61, doi. 10.1111/nyas.13559
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- Publication type:
- Article
Organic dust-induced mitochondrial dysfunction could be targeted via cGAS-STING or cytoplasmic NOX-2 inhibition using microglial cells and brain slice culture models.
- Published in:
- Cell & Tissue Research, 2021, v. 384, n. 2, p. 465, doi. 10.1007/s00441-021-03422-x
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- Publication type:
- Article
Interleukin‐6 and lactate dehydrogenase expression in a novel ex vivo rocking model of equine corneal epithelial wound healing.
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- Veterinary Ophthalmology, 2021, v. 24, n. 5, p. 509, doi. 10.1111/vop.12935
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- Publication type:
- Article
Microglial immune regulation by epigenetic reprogramming through histone H3K27 acetylation in neuroinflammation.
- Published in:
- Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1052925
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- Publication type:
- Article
Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice.
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- Science Translational Medicine, 2018, v. 10, n. 465, p. 1, doi. 10.1126/scitranslmed.aah4066
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- Publication type:
- Article
Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein.
- Published in:
- Science Signaling, 2019, v. 12, n. 572, p. N.PAG, doi. 10.1126/scisignal.aau4543
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- Publication type:
- Article
Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells.
- Published in:
- Science Signaling, 2019, v. 12, n. 563, p. N.PAG, doi. 10.1126/scisignal.aat9900
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- Publication type:
- Article
Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCδ proteolytic activation and mitochondrial translocation.
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- Journal of Cellular & Molecular Medicine, 2008, v. 12, n. 6a, p. 2467, doi. 10.1111/j.1582-4934.2008.00293.x
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- Article
Blinded RT‐QuIC Analysis of α‐Synuclein Biomarker in Skin Tissue From Parkinson's Disease Patients.
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- Movement Disorders, 2020, v. 35, n. 12, p. 2230, doi. 10.1002/mds.28242
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- Publication type:
- Article
α-Synuclein real-time quaking-induced conversion in the submandibular glands of Parkinson's disease patients.
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- 2020
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- Publication type:
- journal article
Aggregation-Inhibiting scFv-Based Therapies Protect Mice against AAV1/2-Induced A53T-α-Synuclein Overexpression.
- Published in:
- Biomolecules (2218-273X), 2023, v. 13, n. 8, p. 1203, doi. 10.3390/biom13081203
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- Publication type:
- Article
Mitochondrial stress-induced H4K12 hyperacetylation dysregulates transcription in Parkinson’s disease.
- Published in:
- Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1422362
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- Publication type:
- Article
Epigallocatechin Gallate Protects against TNFα- or H<sub>2</sub>O<sub>2</sub>- Induced Apoptosis by Modulating Iron Related Proteins in a Cell Culture Model.
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- International Journal for Vitamin & Nutrition Research, 2018, v. 88, n. 3/4, p. 158, doi. 10.1024/0300-9831/a000493
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- Publication type:
- Article
Mitochondrial accumulation of polyubiquitinated proteins and differential regulation of apoptosis by polyubiquitination sites Lys-48 and -63.
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- Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 8b, p. 1632, doi. 10.1111/j.1582-4934.2009.00775.x
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- Publication type:
- Article
Functionalized polyanhydride nanoparticles for improved treatment of mitochondrial dysfunction.
- Published in:
- Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 2022, v. 110, n. 2, p. 450, doi. 10.1002/jbm.b.34922
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- Publication type:
- Article
Biodegradable polyanhydride‐based nanomedicines for blood to brain drug delivery.
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- Journal of Biomedical Materials Research, Part A, 2018, v. 106, n. 11, p. 2881, doi. 10.1002/jbm.a.36477
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- Publication type:
- Article
Neuroprotective Effect of Green Tea Polyphenol, EGCG in Animal Model of Parkinson's Disease.
- Published in:
- FASEB Journal, 2008, v. 22, p. 677, doi. 10.1096/fasebj.22.2_supplement.677
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- Publication type:
- Article
Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson's disease.
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- Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 241, doi. 10.1186/1742-2094-9-241
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- Publication type:
- Article
Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation.
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- Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 82, doi. 10.1186/1742-2094-9-82
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- Publication type:
- Article
Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Enhances Activation of STAT3/NLRC4 Inflammasome Signaling Axis through PKCδ in Astrocytes: Implications for Parkinson's Disease.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 8, p. 1831, doi. 10.3390/cells9081831
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- Publication type:
- Article
Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium.
- Published in:
- Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2021.805135
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- Publication type:
- Article
PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.661505
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- Publication type:
- Article
Utilization of the CRISPR-Cas9 Gene Editing System to Dissect Neuroinflammatory and Neuropharmacological Mechanisms in Parkinson's Disease.
- Published in:
- Journal of NeuroImmune Pharmacology, 2019, v. 14, n. 4, p. 595, doi. 10.1007/s11481-019-09844-3
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- Publication type:
- Article
Ultrasensitive Detection of Aggregated α-Synuclein in Glial Cells, Human Cerebrospinal Fluid, and Brain Tissue Using the RT-QuIC Assay: New High-Throughput Neuroimmune Biomarker Assay for Parkinsonian Disorders.
- Published in:
- Journal of NeuroImmune Pharmacology, 2019, v. 14, n. 3, p. 423, doi. 10.1007/s11481-019-09835-4
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- Publication type:
- Article
Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease.
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- Journal of Neurochemistry, 2017, v. 141, n. 5, p. 766, doi. 10.1111/jnc.14033
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- Publication type:
- Article
Molecular cloning, epigenetic regulation, and functional characterization of Prkd1 gene promoter in dopaminergic cell culture models of Parkinson's disease.
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- Journal of Neurochemistry, 2015, v. 135, n. 2, p. 402, doi. 10.1111/jnc.13261
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- Publication type:
- Article
Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation.
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- Journal of Neurochemistry, 2012, v. 122, n. 5, p. 941, doi. 10.1111/j.1471-4159.2012.07836.x
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- Publication type:
- Article
Neurotoxicity of pesticides.
- Published in:
- Acta Neuropathologica, 2019, v. 138, n. 3, p. 343, doi. 10.1007/s00401-019-02033-9
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- Publication type:
- Article
Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson's Disease.
- Published in:
- Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.631375
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- Publication type:
- Article
Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of Parkinson's disease.
- Published in:
- Frontiers in Neuroscience, 2024, p. 01, doi. 10.3389/fnins.2024.1356703
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- Publication type:
- Article
Emerging Roles of N6-Methyladenosine (m6A) Epitranscriptomics in Toxicology.
- Published in:
- Toxicological Sciences, 2021, v. 181, n. 1, p. 13, doi. 10.1093/toxsci/kfab021
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- Publication type:
- Article
HMGB1-RAGE Signaling Plays a Role in Organic Dust-Induced Microglial Activation and Neuroinflammation.
- Published in:
- Toxicological Sciences, 2019, v. 169, n. 2, p. 579, doi. 10.1093/toxsci/kfz071
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- Publication type:
- Article
Mechanistic Interplay Between Autophagy and Apoptotic Signaling in Endosulfan-Induced Dopaminergic Neurotoxicity: Relevance to the Adverse Outcome Pathway in Pesticide Neurotoxicity.
- Published in:
- Toxicological Sciences, 2019, v. 169, n. 2, p. 333, doi. 10.1093/toxsci/kfz049
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- Publication type:
- Article
Exosomes in Toxicology: Relevance to Chemical Exposure and Pathogenesis of Environmentally Linked Diseases.
- Published in:
- Toxicological Sciences, 2017, v. 158, n. 1, p. 3, doi. 10.1093/toxsci/kfx074
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- Publication type:
- Article
α-Synuclein Protects Against Manganese Neurotoxic Insult During the Early Stages of Exposure in a Dopaminergic Cell Model of Parkinson’s Disease.
- Published in:
- Toxicological Sciences, 2015, v. 143, n. 2, p. 454, doi. 10.1093/toxsci/kfu247
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- Publication type:
- Article
Manganese Upregulates Cellular Prion Protein and Contributes to Altered Stabilization and Proteolysis: Relevance to Role of Metals in Pathogenesis of Prion Disease.
- Published in:
- Toxicological Sciences, 2010, v. 115, n. 2, p. 535, doi. 10.1093/toxsci/kfq049
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- Publication type:
- Article
Normal Cellular Prion Protein Protects against Manganese-Induced Oxidative Stress and Apoptotic Cell Death.
- Published in:
- Toxicological Sciences, 2007, v. 98, n. 2, p. 495, doi. 10.1093/toxsci/kfm099
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- Publication type:
- Article
Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease.
- Published in:
- NPJ Parkinson's Disease, 2017, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41531-017-0032-2
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- Publication type:
- Article
Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration.
- Published in:
- Nature Communications, 2016, v. 7, n. 10, p. 12932, doi. 10.1038/ncomms12932
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- Publication type:
- Article
Status Epilepticus: Behavioral and Electroencephalography Seizure Correlates in Kainate Experimental Models.
- Published in:
- Frontiers in Neurology, 2018, p. 1, doi. 10.3389/fneur.2018.00007
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- Publication type:
- Article
Protein Kinase D1 (PKD1) Phosphorylation Promotes Dopaminergic Neuronal Survival during 6-OHDA-Induced Oxidative Stress.
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096947
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- Publication type:
- Article
Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorders.
- Published in:
- Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.836605
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- Publication type:
- Article
Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 27, p. 10058, doi. 10.1523/JNEUROSCI.0302-15.2015
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- Publication type:
- Article
α-Synuclein Negatively Regulates Protein Kinase Cδ Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity.
- Published in:
- Journal of Neuroscience, 2011, v. 31, n. 6, p. 2035, doi. 10.1523/JNEUROSCI.5634-10.2011
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- Publication type:
- Article
Differential arousal regulation by prokineticin 2 signaling in the nocturnal mouse and the diurnal monkey.
- Published in:
- Molecular Brain, 2016, v. 9, p. 1, doi. 10.1186/s13041-016-0255-x
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- Publication type:
- Article
Caspase-3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1-methyl-4-phenylpyridinium (MPP[sup +] )-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
- Published in:
- European Journal of Neuroscience, 2003, v. 18, n. 6, p. 1387, doi. 10.1046/j.1460-9568.2003.02864.x
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- Publication type:
- Article
Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation.
- Published in:
- Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2019.00654
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- Publication type:
- Article
Protein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degeneration.
- Published in:
- Molecular Neurodegeneration, 2011, v. 6, n. 1, p. 43, doi. 10.1186/1750-1326-6-43
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- Publication type:
- Article
Organic dust exposure induces stress response and mitochondrial dysfunction in monocytic cells.
- Published in:
- Histochemistry & Cell Biology, 2021, v. 155, n. 6, p. 699, doi. 10.1007/s00418-021-01978-x
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- Publication type:
- Article
An Ex Vivo Brain Slice Culture Model of Chronic Wasting Disease: Implications for Disease Pathogenesis and Therapeutic Development.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64456-9
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- Publication type:
- Article