Works by Kanji Komatsu

Results: 10

DPP-4 inhibition with alogliptin on top of angiotensin II type 1 receptor blockade ameliorates albuminuria via up-regulation of SDF-1α in type 2 diabetic patients with incipient nephropathy.

Published in:

Endocrine Journal, 2014, v. 61, n. 2, p. 159, doi. 10.1507/endocrj.ej13-0305

By:

Hiroki Fujita;
Hisanori Taniai;
Hiroko Murayama;
Haruyo Ohshiro;
Hikaru Hayashi;
Seiko Sato;
Nyuko Kikuchi;
Taiga Komatsu;
Koga Komatsu;
Kanji Komatsu;
Takuma Narita;
Yuichiro Yamada

Publication type:

Article

ASP8273 tolerability and antitumor activity in tyrosine kinase inhibitor‐naïve Japanese patients with EGFR mutation‐positive non‐small‐cell lung cancer.

Published in:

Cancer Science, 2018, v. 109, n. 8, p. 2532, doi. 10.1111/cas.13651

By:

Azuma, Koichi;
Nishio, Makoto;
Hayashi, Hidetoshi;
Kiura, Katsuyuki;
Satouchi, Miyako;
Sugawara, Shunichi;
Hida, Toyoaki;
Iwamoto, Yasuo;
Inoue, Akira;
Takeda, Koji;
Ikeda, Satoshi;
Nakagawa, Tomoki;
Takeda, Kentaro;
Asahina, Seitaro;
Komatsu, Kanji;
Morita, Satoshi;
Fukuoka, Masahiro;
Nakagawa, Kazuhiko

Publication type:

Article

A Model‐Based Trial Design With a Randomization Scheme Considering Pharmacokinetics Exposure for Dose Optimization in Oncology.

Published in:

Pharmaceutical Statistics, 2025, v. 24, n. 2, p. 1, doi. 10.1002/pst.2454

By:

Zhang, Jun;
Takeda, Kentaro;
Takeuchi, Masato;
Komatsu, Kanji;
Zhu, Jing;
Yamaguchi, Yusuke

Publication type:

Article

Bayesian dose‐finding phase I trial design incorporating pharmacokinetic assessment in the field of oncology.

Published in:

Pharmaceutical Statistics, 2018, v. 17, n. 6, p. 725, doi. 10.1002/pst.1890

By:

Takeda, Kentaro;
Komatsu, Kanji;
Morita, Satoshi

Publication type:

Article

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 572, doi. 10.1002/psp4.13297

By:

Yamada, Akihiro;
Choules, Mary P.;
Brightman, Frances A.;
Takeshita, Shigeru;
Nakao, Shinsuke;
Amino, Nobuaki;
Nakayama, Takeshi;
Takeuchi, Masato;
Komatsu, Kanji;
Ortega, Fernando;
Mistry, Hitesh;
Orrell, David;
Chassagnole, Christophe;
Bonate, Peter L.

Publication type:

Article

Physiologically‐Based Pharmacokinetic Modeling for the Prediction of a Drug–Drug Interaction of Combined Effects on P‐glycoprotein and Cytochrome P450 3A.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 11, p. 659, doi. 10.1002/psp4.12562

By:

Otsuka, Yukio;
Choules, Mary P.;
Bonate, Peter L.;
Komatsu, Kanji

Publication type:

Article

Population pharmacokinetics of roxadustat in Japanese dialysis‐dependent chronic kidney disease patients with anaemia.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 2, p. 787, doi. 10.1111/bcp.15023

By:

Takada, Akitsugu;
Shibata, Tomohisa;
Shiga, Takanori;
Groenendaal‐van de Meent, Dorien;
Komatsu, Kanji

Publication type:

Article

Population Pharmacokinetic Modeling and Simulation of Pudexacianinium (ASP5354) for Dose Setting of a Phase 2 First‐in‐Patient Study: A Novel Imaging Agent for Intraoperative Ureter Visualization during Abdominopelvic Surgery.

Published in:

Clinical Pharmacology in Drug Development, 2024, v. 13, n. 5, p. 454, doi. 10.1002/cpdd.1354

By:

Saito, Masako;
Kojima, Tomoki;
Komatsu, Kanji;
Takusagawa, Shin

Publication type:

Article

A phase 1 study of oral ASP5878, a selective small-molecule inhibitor of fibroblast growth factor receptors 1–4, as a single dose and multiple doses in patients with solid malignancies.

Published in:

Investigational New Drugs, 2020, v. 38, n. 2, p. 445, doi. 10.1007/s10637-019-00780-w

By:

Yamamoto, Noboru;
Ryoo, Baek-Yeol;
Keam, Bhumsuk;
Kudo, Masatoshi;
Lin, Chia-Chi;
Kunieda, Futoshi;
Ball, Howard A.;
Moran, Diarmuid;
Komatsu, Kanji;
Takeda, Kentaro;
Fukuda, Musashi;
Furuse, Junji;
Morita, Satoshi;
Doi, Toshihiko

Publication type:

Article

A phase 2a, randomized, double-blind, placebo-controlled trial of the efficacy and safety of the oral gonadotropin-releasing hormone antagonist, ASP1707, in postmenopausal female patients with rheumatoid arthritis taking methotrexate.

Published in:

Modern Rheumatology, 2021, v. 31, n. 1, p. 53, doi. 10.1080/14397595.2020.1733214

By:

Tsutomu Takeuchi;
Yoshiya Tanaka;
Chieri Higashitani;
Megumi Iwai;
Kanji Komatsu;
Rio Akazawa;
Lademacher, Christopher

Publication type:

Article