Works matching AU Kanemaki, Masato T.

Results: 36

DNA methylation protects cancer cells against senescence.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61157-7

By:

Chen, Xiaoying;
Yamaguchi, Kosuke;
Rodgers, Brianna;
Goehrig, Delphine;
Vindrieux, David;
Lahaye, Xavier;
Nolot, Matthieu;
Ferry, Laure;
Lanciano, Sophie;
Martin, Nadine;
Dubus, Pierre;
Miura, Fumihito;
Ito, Takashi;
Cristofari, Gael;
Manel, Nicolas;
Kanemaki, Masato T.;
Bernard, David;
Defossez, Pierre-Antoine

Publication type:

Article

The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60817-y

By:

Dong, Qianqian;
Day, Matthew;
Saito, Yuichiro;
Parker, Emma;
Watts, Lotte P.;
Kanemaki, Masato T.;
Oliver, Antony W.;
Pearl, Laurence H.;
Hiraga, Shin-ichiro;
Donaldson, Anne D.

Publication type:

Article

Monoclonal antibody generation by controlled immunoglobulin gene rearrangements.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07690-z

By:

Murayama, Akiho;
Matsui, Shin;
Abe, Takuya;
Kanemaki, Masato T.;
Kurosawa, Kohei;
Hirota, Kouji;
Ohta, Kunihiro;
Seo, Hidetaka

Publication type:

Article

The Depletion of TRAIP Results in the Retention of PCNA on Chromatin During Mitosis Leads to Inhibiting DNA Replication Initiation.

Published in:

Genes to Cells, 2025, v. 30, n. 2, p. 1, doi. 10.1111/gtc.70006

By:

Shiomi, Yasushi;
Hayashi, Akiyo;
Saito, Yuichiro;
Kanemaki, Masato T.;
Nishitani, Hideo

Publication type:

Article

Overexpression of JNK‐associated leucine zipper protein induces chromosomal instability through interaction with dynein light intermediate chain 1.

Published in:

Genes to Cells, 2024, v. 29, n. 1, p. 39, doi. 10.1111/gtc.13083

By:

Suzuki, Ryusuke;
Kanemaki, Masato T.;
Suzuki, Takeshi;
Yoshioka, Katsuji

Publication type:

Article

Visualizing looping of two endogenous genomic loci using synthetic zinc‐finger proteins with anti‐FLAG and anti‐HA frankenbodies in living cells.

Published in:

Genes to Cells, 2021, v. 26, n. 11, p. 905, doi. 10.1111/gtc.12893

By:

Liu, Yang;
Zhao, Ning;
Kanemaki, Masato T.;
Yamamoto, Yotaro;
Sadamura, Yoshifusa;
Ito, Yuma;
Tokunaga, Makio;
Stasevich, Timothy J.;
Kimura, Hiroshi

Publication type:

Article

Perichromosomal protein Ki67 supports mitotic chromosome architecture.

Published in:

Genes to Cells, 2016, v. 21, n. 10, p. 1113, doi. 10.1111/gtc.12420

By:

Takagi, Masatoshi;
Natsume, Toyoaki;
Kanemaki, Masato T.;
Imamoto, Naoko

Publication type:

Article

SRBD1 facilitates chromosome segregation by promoting topoisomerase IIα localization to mitotic chromosomes.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56911-w

By:

Lovejoy, Courtney A.;
Wessel, Sarah R.;
Bhowmick, Rahul;
Hatoyama, Yuki;
Kanemaki, Masato T.;
Zhao, Runxiang;
Cortez, David

Publication type:

Article

Cell-type specific, inducible and acute degradation of targeted protein in mice by two degron systems.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54308-9

By:

Yamashita, Motoi;
Ogawa, Chihiro;
Zhang, Baihao;
Kobayashi, Tetsuro;
Nomura, Aneela;
Barker, Clive;
Zou, Chengcheng;
Yamanaka, Satoshi;
Hayashi, Ken-ichiro;
Shinkai, Yoichi;
Moro, Kazuyo;
Fargarasan, Sidonia;
Imami, Koshi;
Seita, Jun;
Shirai, Fumiyuki;
Sawasaki, Tatsuya;
Kanemaki, Masato T.;
Taniuchi, Ichiro

Publication type:

Article

RecQ4 promotes the conversion of the pre-initiation complex at a site-specific origin for DNA unwinding in Xenopus egg extracts.

Published in:

Cell Cycle, 2015, v. 14, n. 7, p. 1010, doi. 10.1080/15384101.2015.1007003

By:

Sanuki, Yosuke;
Kubota, Yumiko;
Kanemaki, Masato T;
Takahashi, Tatsuro S;
Mimura, Satoru;
Takisawa, Haruhiko

Publication type:

Article

The dimeric Mcm8-9 complex of Xenopus laevis likely has a conserved function for resistance to DNA damage.

Published in:

Cell Cycle, 2013, v. 12, n. 9, p. 1338, doi. 10.4161/cc.24670

By:

Kanemaki, Masato T.

Publication type:

Article

Inhibiting the MCM8‐9 complex selectively sensitizes cancer cells to cisplatin and olaparib.

Published in:

Cancer Science, 2019, v. 110, n. 3, p. 1044, doi. 10.1111/cas.13941

By:

Morii, Issay;
Iwabuchi, Yukiko;
Mori, Sumiko;
Suekuni, Masaki;
Natsume, Toyoaki;
Yoshida, Kazumasa;
Sugimoto, Nozomi;
Kanemaki, Masato T.;
Fujita, Masatoshi

Publication type:

Article

CHAMP1 premature termination codon mutations found in individuals with intellectual disability cause a homologous recombination defect through haploinsufficiency.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-83435-y

By:

Yoshizaki, Yujiro;
Ouchi, Yunosuke;
Kurniawan, Dicky;
Yumoto, Eisuke;
Yoneyama, Yuki;
Rizqullah, Faiza Ramadhani;
Sato, Hiyori;
Sarholz, Mirjam Hanako;
Natsume, Toyoaki;
Kanemaki, Masato T.;
Ikeda, Masanori;
Ui, Ayako;
Iemura, Kenji;
Tanaka, Kozo

Publication type:

Article

Constructing Auxin-Inducible Degron Mutants Using an All-in-One Vector.

Published in:

Pharmaceuticals (14248247), 2020, v. 13, n. 5, p. 103, doi. 10.3390/ph13050103

By:

Yesbolatova, Aisha;
Saito, Yuichiro;
Kanemaki, Masato T.

Publication type:

Article

Mitotic DNA synthesis in response to replication stress requires the sequential action of DNA polymerases zeta and delta in human cells.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-35992-5

By:

Wu, Wei;
Barwacz, Szymon A.;
Bhowmick, Rahul;
Lundgaard, Katrine;
Gonçalves Dinis, Marisa M.;
Clausen, Malgorzata;
Kanemaki, Masato T.;
Liu, Ying

Publication type:

Article

Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B.

Published in:

EMBO Journal, 2020, v. 39, n. 11, p. 1, doi. 10.15252/embj.2020104419

By:

Hégarat, Nadia;
Crncec, Adrijana;
Suarez Peredo Rodriguez, Maria F;
Echegaray Iturra, Fabio;
Gu, Yan;
Busby, Oliver;
Lang, Paul F;
Barr, Alexis R;
Bakal, Chris;
Kanemaki, Masato T;
Lamond, Angus I;
Novak, Bela;
Ly, Tony;
Hochegger, Helfrid

Publication type:

Article

Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47314-4

By:

Kosuke Yamaguchi;
Xiaoying Chen;
Rodgers, Brianna;
Fumihito Miura;
Bashtrykov, Pavel;
Bonhomme, Frédéric;
Salinas-Luypaert, Catalina;
Haxholli, Deis;
Gutekunst, Nicole;
Aygenli, Bihter Özdemir;
Ferry, Laure;
Kirsh, Olivier;
Laisné, Marthe;
Scelfo, Andrea;
Ugur, Enes;
Arimondo, Paola B.;
Leonhardt, Heinrich;
Kanemaki, Masato T.;
Bartke, Till;
Fachinetti, Daniele

Publication type:

Article

Ran-GTP assembles a specialized spindle structure for accurate chromosome segregation in medaka early embryos.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45251-w

By:

Kiyomitsu, Ai;
Nishimura, Toshiya;
Hwang, Shiang Jyi;
Ansai, Satoshi;
Kanemaki, Masato T.;
Tanaka, Minoru;
Kiyomitsu, Tomomi

Publication type:

Article

TRAIP resolves DNA replication-transcription conflicts during the S-phase of unperturbed cells.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40695-y

By:

Scaramuzza, Shaun;
Jones, Rebecca M.;
Sadurni, Martina Muste;
Reynolds-Winczura, Alicja;
Poovathumkadavil, Divyasree;
Farrell, Abigail;
Natsume, Toyoaki;
Rojas, Patricia;
Cuesta, Cyntia Fernandez;
Kanemaki, Masato T.;
Saponaro, Marco;
Gambus, Agnieszka

Publication type:

Article

Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase II.

Published in:

Journal of Cell Biology, 2019, v. 218, n. 5, p. 1511, doi. 10.1083/jcb.201811090

By:

Michael Babokhov;
Tadasu Nozaki;
Sachiko Tamura;
Ryosuke Nagashima;
Kayo Hibino;
Ryosuke Imai;
Kazuhiro Maeshima;
Kanemaki, Masato T.;
Ashwin, S. S.;
Shin Fujishiro;
Masaki Sasai;
Tomomi Tani;
Michael Shribak;
Hiroshi Kimura

Publication type:

Article

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.

Published in:

Nature Communications, 2017, v. 8, n. 5, p. 15287, doi. 10.1038/ncomms15287

By:

Takahashi, Akiko;
Okada, Ryo;
Nagao, Koji;
Kawamata, Yuka;
Hanyu, Aki;
Yoshimoto, Shin;
Takasugi, Masaki;
Watanabe, Sugiko;
Kanemaki, Masato T;
Obuse, Chikashi;
Hara, Eiji

Publication type:

Article

Publisher Correction: Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06613-3

By:

Takahashi, Akiko;
Okada, Ryo;
Nagao, Koji;
Kawamata, Yuka;
Hanyu, Aki;
Yoshimoto, Shin;
Takasugi, Masaki;
Watanabe, Sugiko;
Kanemaki, Masato T.;
Obuse, Chikashi;
Hara, Eiji

Publication type:

Article

Targeted Protein Depletion Using the Auxin-Inducible Degron 2 (AID2) System.

Published in:

Current Protocols, 2021, v. 1, n. 8, p. 1, doi. 10.1002/cpz1.219

By:

Yuichiro Saito;
Kanemaki, Masato T.

Publication type:

Article

MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.77393

By:

Yuichiro Saito;
Venny Santosa;
Kei-ichiro Ishiguro;
Kanemaki, Masato T.

Publication type:

Article

Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines.

Published in:

Genes to Cells, 2015, v. 20, n. 12, p. 1059, doi. 10.1111/gtc.12310

By:

Hoa, Nguyen Ngoc;
Akagawa, Remi;
Yamasaki, Tomomi;
Hirota, Kouji;
Sasa, Kentaro;
Natsume, Toyoaki;
Kobayashi, Junya;
Sakuma, Tetsushi;
Yamamoto, Takashi;
Komatsu, Kenshi;
Kanemaki, Masato T.;
Pommier, Yves;
Takeda, Shunichi;
Sasanuma, Hiroyuki

Publication type:

Article

The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19532-z

By:

Yesbolatova, Aisha;
Saito, Yuichiro;
Kitamoto, Naomi;
Makino-Itou, Hatsune;
Ajima, Rieko;
Nakano, Risako;
Nakaoka, Hirofumi;
Fukui, Kosuke;
Gamo, Kanae;
Tominari, Yusuke;
Takeuchi, Haruki;
Saga, Yumiko;
Hayashi, Ken-ichiro;
Kanemaki, Masato T.

Publication type:

Article

RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04369-7

By:

Sugawara, Sho;
Okada, Ryo;
Loo, Tze Mun;
Tanaka, Hisamichi;
Miyata, Kenichi;
Chiba, Masatomo;
Kawasaki, Hiroko;
Katoh, Kaoru;
Kaji, Shizuo;
Maezawa, Yoshiro;
Yokote, Koutaro;
Nakayama, Mizuho;
Oshima, Masanobu;
Nagao, Koji;
Obuse, Chikashi;
Nagayama, Satoshi;
Takubo, Keiyo;
Nakanishi, Akira;
Kanemaki, Masato T.;
Hara, Eiji

Publication type:

Article

The auxin-inducible degron 2 (AID2) system enables controlled protein knockdown during embryogenesis and development in Caenorhabditis elegans.

Published in:

Genetics, 2022, v. 220, n. 2, p. 1, doi. 10.1093/genetics/iyab218

By:

Takefumi Negishi;
Saho Kitagawa;
Natsumi Horii;
Yuka Tanaka;
Nami Haruta;
Asako Sugimoto;
Hitoshi Sawa;
Ken-ichiro Hayashi;
Masahiko Harata;
Kanemaki, Masato T.

Publication type:

Article

The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.58020

By:

Watts, Lotte P.;
Toyoaki Natsume;
Yuichiro Saito;
Garzon, Javier;
Qianqian Dong;
Boteva, Lora;
Gilbert, Nick;
Kanemaki, Masato T.;
Shin-ichiro Hiraga;
Donaldson, Anne D.

Publication type:

Article

Endosomal Rab cycles regulate Parkin-mediated mitophagy.

Published in:

eLife, 2018, p. 1, doi. 10.7554/eLife.31326

By:

Koji Yamano;
Chunxin Wang;
Sarraf, Shireen A.;
Münch, Christian;
Kikuchi, Reika;
Noda, Nobuo N.;
Yohei Hizukuri;
Kanemaki, Masato T.;
Harper, Wade;
Tanaka, Keiji;
Noriyuki Matsuda;
Youle, Richard J.

Publication type:

Article

Establishment and characterization of mouse lines useful for endogenous protein degradation via an improved auxin‐inducible degron system (AID2).

Published in:

Development, Growth & Differentiation, 2024, v. 66, n. 7, p. 384, doi. 10.1111/dgd.12942

By:

Makino‐Itou, Hatsune;
Yamatani, Noriko;
Okubo, Akemi;
Kiso, Makoto;
Ajima, Rieko;
Kanemaki, Masato T.;
Saga, Yumiko

Publication type:

Article

Redundant roles of extra-cellular signal-regulated kinase (ERK) 1 and 2 in the G1-S transition and etoposide-induced G2/M checkpoint in HCT116 cells.

Published in:

Drug Discoveries & Therapeutics, 2023, v. 17, n. 1, p. 10, doi. 10.5582/ddt.2022.01120

By:

Purev Erdenebaatar;
I Ketut Gunarta;
Ryusuke Suzuki;
Ravdandorj Odongoo;
Toshihiro Fujii;
Rikiro Fukunaga;
Masato T Kanemaki;
Katsuji Yoshioka

Publication type:

Article

Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns.

Published in:

EMBO Reports, 2024, v. 25, n. 9, p. 4062, doi. 10.1038/s44319-024-00224-4

By:

Hatoyama, Yuki;
Islam, Moutushi;
Bond, Adam G;
Hayashi, Ken-ichiro;
Ciulli, Alessio;
Kanemaki, Masato T

Publication type:

Article

Chromatin folding and DNA replication inhibition mediated by a highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex.

Published in:

Scientific Reports, 2016, p. 24712, doi. 10.1038/srep24712

By:

Imai, Ryosuke;
Komeda, Seiji;
Shimura, Mari;
Tamura, Sachiko;
Matsuyama, Satoshi;
Nishimura, Kohei;
Rogge, Ryan;
Matsunaga, Akihiro;
Hiratani, Ichiro;
Takata, Hideaki;
Uemura, Masako;
Iida, Yutaka;
Yoshikawa, Yuko;
Hansen, Jeffrey C.;
Yamauchi, Kazuto;
Kanemaki, Masato T.;
Maeshima, Kazuhiro

Publication type:

Article

Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism.

Published in:

Genome Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13059-024-03212-y

By:

Pujadas Liwag, Emily M.;
Wei, Xiaolong;
Acosta, Nicolas;
Carter, Lucas M.;
Yang, Jiekun;
Almassalha, Luay M.;
Jain, Surbhi;
Daneshkhah, Ali;
Rao, Suhas S. P.;
Seker-Polat, Fidan;
MacQuarrie, Kyle L.;
Ibarra, Joe;
Agrawal, Vasundhara;
Aiden, Erez Lieberman;
Kanemaki, Masato T.;
Backman, Vadim;
Adli, Mazhar

Publication type:

Article

The assembly of the MCM2–7 hetero-hexamer and its significance in DNA replication.

Published in:

Biochemical Society Transactions, 2023, v. 51, n. 3, p. 1289, doi. 10.1042/BST20221465

By:

Yuki Hatoyama;
Masato T. Kanemaki

Publication type:

Article