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Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01199-2
By:
- Reddy, Joseph S.;
- Allen, Mariet;
- Ho, Charlotte C. G.;
- Oatman, Stephanie R.;
- İş, Özkan;
- Quicksall, Zachary S.;
- Wang, Xue;
- Jin, Jiangli;
- Patel, Tulsi A.;
- Carnwath, Troy P.;
- Nguyen, Thuy T.;
- Malphrus, Kimberly G.;
- Lincoln, Sarah J.;
- Carrasquillo, Minerva M.;
- Crook, Julia E.;
- Kanekiyo, Takahisa;
- Murray, Melissa E.;
- Bu, Guojun;
- Dickson, Dennis W.;
- Ertekin-Taner, Nilüfer
Publication type:
Article
Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression.
Published in:
2019
By:
- Yamazaki, Yu;
- Shinohara, Mitsuru;
- Shinohara, Motoko;
- Yamazaki, Akari;
- Murray, Melissa E;
- Liesinger, Amanda M;
- Heckman, Michael G;
- Lesser, Elizabeth R;
- Parisi, Joseph E;
- Petersen, Ronald C;
- Dickson, Dennis W;
- Kanekiyo, Takahisa;
- Bu, Guojun
Publication type:
journal article
Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 9, p. 6590, doi. 10.1002/alz.13877
By:
- Kloske, Courtney M.;
- Belloy, Michael E.;
- Blue, Elizabeth E.;
- Bowman, Gregory R.;
- Carrillo, Maria C.;
- Chen, Xiaoying;
- Chiba‐Falek, Ornit;
- Davis, Albert A.;
- Paolo, Gilbert Di;
- Garretti, Francesca;
- Gate, David;
- Golden, Lesley R.;
- Heinecke, Jay W.;
- Herz, Joachim;
- Huang, Yadong;
- Iadecola, Costantino;
- Johnson, Lance A.;
- Kanekiyo, Takahisa;
- Karch, Celeste M.;
- Khvorova, Anastasia
Publication type:
Article
Relationships between PET and blood plasma biomarkers in corticobasal syndrome.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 7, p. 4765, doi. 10.1002/alz.13914
By:
- Singh, Neha Atulkumar;
- Alnobani, Alla;
- Graff‐Radford, Jonathan;
- Machulda, Mary M.;
- Mielke, Michelle M.;
- Schwarz, Christopher G.;
- Senjem, Matthew L.;
- Jack, Clifford R.;
- Lowe, Val J.;
- Kanekiyo, Takahisa;
- Josephs, Keith A.;
- Whitwell, Jennifer L.
Publication type:
Article
Pharmacological inhibition of sFRP1 stimulates the non‐amyloidogenic pathway of amyloid precursor protein proteolytic processing.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.076527
By:
- Lu, Wenyan;
- Macyczko, Jesse R;
- Martens, Yuka A;
- Bu, Guojun;
- Kanekiyo, Takahisa;
- Li, Yonghe
Publication type:
Article
Gliovascular molecular alterations in Alzheimer's disease: a cross‐tissue, cross‐species study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073806
By:
- Is, Ozkan;
- Wang, Xue;
- Reddy, Joseph S.;
- Patel, Tulsi;
- Min, Yuhao;
- Quicksall, Zachary;
- Heckman, Michael G.;
- Gao, Junli;
- Bergman, Jeremiah;
- Da Mesquita, Sandro Gabriel Ferreira;
- Kizil, Caghan;
- Bhattarai, Prabesh;
- Cosacak, Mehmet I.;
- Lee, Annie J;
- Vardarajan, Badri N;
- Mayeux, Richard;
- Koga, Shunsuke;
- Kanekiyo, Takahisa;
- White, Launia J;
- Kouri, Naomi
Publication type:
Article
DNA methylation clustered by predicted chromatin state reveals distinct association patterns with neuropathologic and biochemical measures in the AD brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072470
By:
- Oatman, Stephanie R;
- Quicksall, Zachary;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Wang, Xue;
- Liu, Chia‐Chen;
- Yamazaki, Yu;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Heckman, Michael G.;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E.;
- Kanekiyo, Takahisa;
- Bu, Guojun;
- Dickson, Dennis W.;
- Allen, Mariet;
- Ertekin‐Taner, Nilufer
Publication type:
Article
DNA methylation clustered by predicted chromatin state reveals distinct association patterns with neuropathologic and biochemical measures in the AD brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072470
By:
- Oatman, Stephanie R;
- Quicksall, Zachary;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Wang, Xue;
- Liu, Chia‐Chen;
- Yamazaki, Yu;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Heckman, Michael G.;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E.;
- Kanekiyo, Takahisa;
- Bu, Guojun;
- Dickson, Dennis W.;
- Allen, Mariet;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Transcriptome profiling in AD cases to identify distinct associations with AD‐related neuropathology and protein levels in the brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.067201
By:
- Allen, Mariet;
- Quicksall, Zachary;
- Wang, Xue;
- Reddy, Joseph S.;
- Bergman, Jeremiah;
- Oatman, Stephanie R;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Lincoln, Sarah J.;
- Yamazaki, Yu;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E.;
- Liu, Chia‐Chen;
- Kanekiyo, Takahisa;
- Dickson, Dennis W.;
- Bu, Guojun;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Association of DNA methylation from the temporal cortex and cerebellum with AD‐related neuropathology and biochemistry.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.060867
By:
- Oatman, Stephanie R;
- Allen, Mariet;
- Quicksall, Zachary;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Wang, Xue;
- Liu, Chia‐Chen;
- Yamazaki, Yu;
- Nguyen, Thuy;
- Heckman, Michael G.;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E.;
- Kanekiyo, Takahisa;
- Dickson, Dennis W.;
- Bu, Guojun;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Genome‐wide analysis identifies novel genetic variants and unique biological pathways associated with AD‐related proteins in the brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055337
By:
- Oatman, Stephanie R;
- Reddy, Joseph S.;
- Quicksall, Zachary;
- Carrasquillo, Minerva M.;
- Wang, Xue;
- Liu, Chia‐Chen;
- Yamazaki, Yu;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Heckman, Michael G.;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E;
- Kanekiyo, Takahisa;
- Dickson, Dennis W;
- Bu, Guojun;
- Allen, Mariet;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Cell type‐specific gene expression changes in Alzheimer's patients with varying levels of cerebral amyloid angiopathy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.052394
By:
- Patel, Tulsi;
- Udine, Evan;
- Wang, Xue;
- Allen, Mariet;
- Is, Ozkan;
- Tutor‐New, Frederick Q;
- Carnwath, Troy;
- Deniz, Kaancan;
- Lincoln, Sarah J.;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Quicksall, Zachary;
- Lewis‐Tuffin, Laura;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Crook, Julia E.;
- Kanekiyo, Takahisa;
- Murray, Melissa E;
- Bu, Guojun;
- Dickson, Dennis W
Publication type:
Article
P3‐088: LIPOSOME‐MEDIATED NGF GENE TRANSFECTION AND POTENTIAL THERAPEUTIC APPLICATION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P959, doi. 10.1016/j.jalz.2019.06.3115
By:
- Rodrigues, Bruna;
- Kanekiyo, Takahisa;
- Singh, Jagdish
Publication type:
Article
P4‐229: LIPOSOMAL NANOPARTICLES FOR GENE DELIVERY TO THE BRAIN.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1529, doi. 10.1016/j.jalz.2018.07.050
By:
- Rodrigues, Bruna;
- Oue, Hiroshi;
- Kanekiyo, Takahisa;
- Singh, Jagdish
Publication type:
Article
P4‐065: APOE4 CONDITIONALLY EXPRESSED IN CEREBROVASCULATURE IMPAIRS ENDOTHELIAL FUNCTIONS AND INDUCES COGNITIVE DEFICITS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1457, doi. 10.1016/j.jalz.2018.06.2468
By:
- Yamazaki, Yu;
- Liu, Chia-Chen;
- Oue, Hiroshi;
- Kurti, Aishe;
- Yamazaki, Akari;
- Fryer, John D.;
- Kanekiyo, Takahisa;
- Bu, Guojun
Publication type:
Article
5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 6, p. 1488, doi. 10.3390/ijms20061488
By:
- Zhao, Jing;
- Fu, Yuan;
- Liu, Chia-Chen;
- Shinohara, Motoko;
- Shinohara, Mitsuru;
- Kanekiyo, Takahisa;
- Bu, Guojun
Publication type:
Article
Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer's Disease.
Published in:
International Journal of Molecular Sciences, 2017, v. 18, n. 9, p. 1965, doi. 10.3390/ijms18091965
By:
- Yu Yamazaki;
- Takahisa Kanekiyo
Publication type:
Article
CMV DNA detection in dried blood spots for diagnosing congenital CMV infection in Japan.
Published in:
Journal of Medical Virology, 2006, v. 78, n. 7, p. 923
By:
- Yoshiaki Yamagishi;
- Hiromi Miyagawa;
- Kazuko Wada;
- Sayuri Matsumoto;
- Hitomi Arahori;
- Arihiro Tamura;
- Hidetoshi Taniguchi;
- Takahisa Kanekiyo;
- Junji Sashihara;
- Tomoko Yoda;
- Mikiya Kitagawa;
- Keiichi Ozono
Publication type:
Article
APOE2 is associated with longevity independent of Alzheimer's disease.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.62199
By:
- Mitsuru Shinohara;
- Takahisa Kanekiyo;
- Masaya Tachibana;
- Kurti, Aishe;
- Motoko Shinohara;
- Yuan Fu;
- Jing Zhao;
- Xianlin Han;
- Sullivan, Patrick M.;
- Rebeck, G. William;
- Fryer, John D.;
- Heckman, Michael G.;
- Guojun Bu
Publication type:
Article
The low-density lipoprotein receptor-related protein1 and amyloid-β clearance in Alzheimer's disease.
Published in:
Frontiers in Aging Neuroscience, 2014, v. 6, p. 1, doi. 10.3389/fnagi.2014.00093
By:
- Takahisa Kanekiyo;
- Guojun Bu
Publication type:
Article
ApoE-2 Brain-Targeted Gene Therapy Through Transferrin and Penetratin Tagged Liposomal Nanoparticles.
Published in:
Pharmaceutical Research, 2019, v. 36, n. 11, p. 1, doi. 10.1007/s11095-019-2691-7
By:
- dos Santos Rodrigues, Bruna;
- Kanekiyo, Takahisa;
- Singh, Jagdish
Publication type:
Article
Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Regulates the Stability and Function of GluA1 α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic Acid (AMPA) Receptor in Neurons.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0113237
By:
- Gan, Ming;
- Jiang, Peizhou;
- McLean, Pamela;
- Kanekiyo, Takahisa;
- Bu, Guojun
Publication type:
Article
Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Mediates Neuronal Aβ42 Uptake and Lysosomal Trafficking.
Published in:
PLoS ONE, 2010, v. 5, n. 7, p. 1
By:
- Fuentealba 1,2, Rodrigo A.;
- Qiang Liu;
- Juan Zhang;
- Kanekiyo, Takahisa;
- Xiaoyan Hu;
- Jin-Moo Lee;
- LaDu, Mary Jo;
- Guojun Bu
Publication type:
Article
ABCA7 and Pathogenic Pathways of Alzheimer's Disease.
Published in:
Brain Sciences (2076-3425), 2018, v. 8, n. 2, p. 27, doi. 10.3390/brainsci8020027
By:
- Aikawa, Tomonori;
- Holm, Marie-Louise;
- Kanekiyo, Takahisa
Publication type:
Article
Apolipoprotein E as a Therapeutic Target in Alzheimer's Disease: A Review of Basic Research and Clinical Evidence.
Published in:
2016
By:
- Yamazaki, Yu;
- Painter, Meghan;
- Bu, Guojun;
- Kanekiyo, Takahisa;
- Painter, Meghan M
Publication type:
journal article
Development and screening of brain-targeted lipid-based nanoparticles with enhanced cell penetration and gene delivery properties.
Published in:
International Journal of Nanomedicine, 2019, v. 14, p. 6497, doi. 10.2147/IJN.S215941
By:
- dos Santos Rodrigues, Bruna;
- Lakkadwala, Sushant;
- Kanekiyo, Takahisa;
- Singh, Jagdish
Publication type:
Article
ABCA7 Regulates Brain Fatty Acid Metabolism During LPS-Induced Acute Inflammation.
Published in:
Frontiers in Neuroscience, 2021, v. 15, p. N.PAG, doi. 10.3389/fnins.2021.647974
By:
- Aikawa, Tomonori;
- Ren, Yingxue;
- Holm, Marie-Louise;
- Asmann, Yan W.;
- Alam, Amer;
- Fitzgerald, Michael L.;
- Bu, Guojun;
- Kanekiyo, Takahisa
Publication type:
Article
Prostaglandin D<sub>2</sub> Protects Neonatal Mouse Brain from Hypoxic Ischemic Injury.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 16, p. 4303, doi. 10.1523/JNEUROSCI.0321-07.2007
By:
- Taniguchi, Hidetoshi;
- Mohri, Ikuko;
- Okabe-Arahori, Hitomi;
- Aritake, Kosuke;
- Wada, Kazuko;
- Kanekiyo, Takahisa;
- Narumiya, Shuh;
- Nakayama, Masahiro;
- Ozono, Keiichi;
- Urade, Yoshihiro;
- Taniike, Masako
Publication type:
Article
Prostaglandin D<sub>2</sub>-Mediated Microglia/Astrocyte Interaction Enhances Astrogliosis and Demyelination in twitcher.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 16, p. 4383, doi. 10.1523/JNEUROSCI.4531-05.2006
By:
- Ikuko Mohri;
- Masako Taniike;
- Hidetoshi Taniguchi;
- Takahisa Kanekiyo;
- Kosuke Aritake;
- Takashi Inui;
- Noriko Fukumoto;
- Eguchi, Naomi;
- Atsuko Kushi;
- Hitoshi Sasai;
- Yoshihide Kanaoka;
- Keiichi Ozono;
- Shuh Narumiya;
- Kinuko Suzuki;
- Yoshihiro Urade
Publication type:
Article
Mesenchymal stem cell therapy for focal epilepsy: A systematic review of preclinical models and clinical studies.
Published in:
Epilepsia (Series 4), 2022, v. 63, n. 7, p. 1607, doi. 10.1111/epi.17266
By:
- Ramos‐Fresnedo, Andres;
- Perez‐Vega, Carlos;
- Domingo, Ricardo A.;
- Lee, Seung Jin;
- Perkerson, Ralph B.;
- Zubair, Abba C.;
- Takahisa, Kanekiyo;
- Tatum, William;
- Quinones‐Hinojosa, Alfredo;
- Middlebrooks, Erik. H.;
- Grewal, Sanjeet S.
Publication type:
Article
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Published in:
2019
By:
- Tachibana, Masaya;
- Holm, Marie-Louise;
- Chia-Chen Liu;
- Mitsuru Shinohara;
- Tomonori Aikawa;
- Hiroshi Oue;
- Yu Yamazaki;
- Martens, Yuka A.;
- Murray, Melissa E.;
- Sullivan, Patrick M.;
- Weyer, Kathrin;
- Glerup, Simon;
- Dickson, Dennis W.;
- Guojun Bu;
- Takahisa Kanekiyo;
- Liu, Chia-Chen;
- Shinohara, Mitsuru;
- Aikawa, Tomonori;
- Oue, Hiroshi;
- Yamazaki, Yu
Publication type:
journal article
Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer’s disease.
Published in:
Science Translational Medicine, 2016, v. 8, n. 332, p. 1, doi. 10.1126/scitranslmed.aad3650
By:
- Chia-Chen Liu;
- Na Zhao;
- Yu Yamaguchi;
- Cirrito, John R.;
- Takahisa Kanekiyo;
- Holtzman, David M.;
- Guojun Bu
Publication type:
Article
APOE2 eases cognitive decline during Aging: Clinical and preclinical evaluations.
Published in:
2016
By:
- Shinohara, Mitsuru;
- Kanekiyo, Takahisa;
- Yang, Longyu;
- Linthicum, Duane;
- Shinohara, Motoko;
- Fu, Yuan;
- Price, Laura;
- Frisch ‐ Daiello, Jessica L.;
- Han, Xianlin;
- Fryer, John D.;
- Bu, Guojun;
- Frisch-Daiello, Jessica L
Publication type:
journal article
APOE ∊4/∊4 diminishes neurotrophic function of human iPSC-derived astrocytes.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 14, p. 2690, doi. 10.1093/hmg/ddx155
By:
- Jing Zhao;
- Davis, Mary D.;
- Martens, Yuka A.;
- Mitsuru Shinohara;
- Graff-Radford, Neill R.;
- Younkin, Steven G.;
- Wszolek, Zbigniew K.;
- Takahisa Kanekiyo;
- Guojun Bu
Publication type:
Article
Identification of plexin A4 as a novel clusterin receptor links two Alzheimer's disease risk genes.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 16, p. 3467, doi. 10.1093/hmg/ddw188
By:
- Kang, Silvia S.;
- Kurti, Aishe;
- Wojtas, Aleksandra;
- Baker, Kelsey E.;
- Liu, Chia-Chen;
- Kanekiyo, Takahisa;
- Deming, Yuetiva;
- Cruchaga, Carlos;
- Estus, Steven;
- Bu, Guojun;
- Fryer, John D.
Publication type:
Article
Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.
Published in:
Acta Neuropathologica, 2016, v. 132, n. 2, p. 225, doi. 10.1007/s00401-016-1580-y
By:
- Shinohara, Mitsuru;
- Murray, Melissa;
- Frank, Ryan;
- Shinohara, Motoko;
- DeTure, Michael;
- Yamazaki, Yu;
- Tachibana, Masaya;
- Atagi, Yuka;
- Davis, Mary;
- Liu, Chia-Chen;
- Zhao, Na;
- Painter, Meghan;
- Petersen, Ronald;
- Fryer, John;
- Crook, Julia;
- Dickson, Dennis;
- Bu, Guojun;
- Kanekiyo, Takahisa
Publication type:
Article
The role of APOE in cerebrovascular dysfunction.
Published in:
Acta Neuropathologica, 2016, v. 131, n. 5, p. 709, doi. 10.1007/s00401-016-1547-z
By:
- Tai, Leon;
- Thomas, Riya;
- Marottoli, Felecia;
- Koster, Kevin;
- Kanekiyo, Takahisa;
- Morris, Alan;
- Bu, Guojun
Publication type:
Article
Differential Effects of Extracellular Vesicles of Lineage-Specific Human Pluripotent Stem Cells on the Cellular Behaviors of Isogenic Cortical Spheroids.
Published in:
Cells (2073-4409), 2019, v. 8, n. 9, p. 993, doi. 10.3390/cells8090993
By:
- Marzano, Mark;
- Bejoy, Julie;
- Cheerathodi, Mujeeb R.;
- Sun, Li;
- York, Sara B.;
- Zhao, Jing;
- Kanekiyo, Takahisa;
- Bu, Guojun;
- Meckes, David G.;
- Li, Yan
Publication type:
Article
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
Published in:
Nature Neuroscience, 2015, v. 18, n. 7, p. 978, doi. 10.1038/nn.4025
By:
- Zhao, Zhen;
- Sagare, Abhay P;
- Ma, Qingyi;
- Halliday, Matthew R;
- Kong, Pan;
- Kisler, Kassandra;
- Winkler, Ethan A;
- Ramanathan, Anita;
- Kanekiyo, Takahisa;
- Bu, Guojun;
- Owens, Nelly Chuqui;
- Rege, Sanket V;
- Si, Gabriel;
- Ahuja, Ashim;
- Zhu, Donghui;
- Miller, Carol A;
- Schneider, Julie A;
- Maeda, Manami;
- Maeda, Takahiro;
- Sugawara, Tohru
Publication type:
Article
Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan.
Published in:
Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0099-y
By:
- Yuan Fu;
- Jing Zhao;
- Yuka Atagi;
- Nielsen, Henrietta M.;
- Chia-Chen Liu;
- Honghua Zheng;
- Mitsuru Shinohara;
- Takahisa Kanekiyo;
- Guojun Bu
Publication type:
Article
Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells.
Published in:
Molecular Neurodegeneration, 2015, v. 10, p. 1, doi. 10.1186/s13024-015-0042-7
By:
- Wren, Melissa C.;
- Jing Zhao;
- Chia-Chen Liu;
- Murray, Melissa E.;
- Yuka Atagi;
- Davis, Mary D.;
- Yuan Fu;
- Okano, Hirotaka J.;
- Kotaro Ogaki;
- Strongosky, Audrey J.;
- Tacik, Pawel;
- Rademakers, Rosa;
- Ross, Owen A.;
- Dickson, Dennis W.;
- Wszolek, Zbigniew K.;
- Takahisa Kanekiyo;
- Bu, Guojun
Publication type:
Article
Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells.
Published in:
Molecular Neurodegeneration, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13024-015-0042-7
By:
- Wren, Melissa C.;
- Jing Zhao;
- Chia-Chen Liu;
- Murray, Melissa E.;
- Yuka Atagi;
- Davis, Mary D.;
- Yuan Fu;
- Okano, Hirotaka J.;
- Kotaro Ogaki;
- Strongosky, Audrey J.;
- Tacik, Pawel;
- Rademakers, Rosa;
- Ross, Owen A.;
- Dickson, Dennis W.;
- Wszolek, Zbigniew K.;
- Takahisa Kanekiyo;
- Guojun Bu
Publication type:
Article
Vascular hypothesis of Alzheimer's disease: role of apoE and apoE receptors.
Published in:
2013
By:
- Guojun Bu;
- Chia-Chen Liu;
- Takahisa Kanekiyo
Publication type:
Abstract
LRP1 plays a major role in the amyloid-β clearance in microglia.
Published in:
2013
By:
- Aurelie N'Songo;
- Takahisa Kanekiyo;
- Guojun Bu
Publication type:
Abstract
LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways.
Published in:
Journal of Neuroinflammation, 2016, v. 13, p. 1, doi. 10.1186/s12974-016-0772-7
By:
- Longyu Yang;
- Chia-Chen Liu;
- Honghua Zheng;
- Takahisa Kanekiyo;
- Yuka Atagi;
- Lin Jia;
- Daxin Wang;
- N'songo, Aurelie;
- Dan Can;
- Huaxi Xu;
- Xiao-Fen Chen;
- Guojun Bu
Publication type:
Article
Gliovascular transcriptional perturbations in Alzheimer's disease reveal molecular mechanisms of blood brain barrier dysfunction.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48926-6
By:
- İş, Özkan;
- Wang, Xue;
- Reddy, Joseph S.;
- Min, Yuhao;
- Yilmaz, Elanur;
- Bhattarai, Prabesh;
- Patel, Tulsi;
- Bergman, Jeremiah;
- Quicksall, Zachary;
- Heckman, Michael G.;
- Tutor-New, Frederick Q.;
- Can Demirdogen, Birsen;
- White, Launia;
- Koga, Shunsuke;
- Krause, Vincent;
- Inoue, Yasuteru;
- Kanekiyo, Takahisa;
- Cosacak, Mehmet Ilyas;
- Nelson, Nastasia;
- Lee, Annie J.
Publication type:
Article
Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease.
Published in:
Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00640-5
By:
- Inoue, Yasuteru;
- Shue, Francis;
- Bu, Guojun;
- Kanekiyo, Takahisa
Publication type:
Article
Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides.
Published in:
Journal of Neurochemistry, 2006, v. 97, n. 3, p. 641, doi. 10.1111/j.1471-4159.2006.03753.x
By:
- Mohri, Ikuko;
- Taniike, Masako;
- Okazaki, Issei;
- Kagitani-Shimono, Kuriko;
- Aritake, Kosuke;
- Kanekiyo, Takahisa;
- Yagi, Takashi;
- Takikita, Shoichi;
- Hyung-Suk Kim;
- Urade, Yoshihiro;
- Suzuki, Kinuko
Publication type:
Article
Multiple system atrophy and apolipoprotein E.
Published in:
2018
By:
- Ogaki, Kotaro;
- Martens, Yuka A.;
- Heckman, Michael G.;
- Koga, Shunsuke;
- Labbé, Catherine;
- Lorenzo‐Betancor, Oswaldo;
- Wernick, Anna I.;
- Walton, Ronald L.;
- Soto, Alexandra I.;
- Vargas, Emily R.;
- Nielsen, Henrietta M.;
- Fujioka, Shinsuke;
- Kanekiyo, Takahisa;
- Uitti, Ryan J.;
- van Gerpen, Jay A.;
- Cheshire, William P.;
- Wszolek, Zbigniew K.;
- Low, Phillip A.;
- Singer, Wolfgang;
- Dickson, Dennis W.
Publication type:
journal article
Secretome from iPSC-derived MSCs exerts proangiogenic and immunosuppressive effects to alleviate radiation-induced vascular endothelial cell damage.
Published in:
Stem Cell Research & Therapy, 2024, v. 15, n. 1, p. 1, doi. 10.1186/s13287-024-03847-5
By:
- Gupta, Kshama;
- Perkerson III, Ralph B.;
- Parsons, Tammee M.;
- Angom, Ramacharan;
- Amerna, Danilyn;
- Burgess, Jeremy D.;
- Ren, Yingxue;
- McLean, Pamela J.;
- Mukhopadhyay, Debabrata;
- Vibhute, Prasanna;
- Wszolek, Zbigniew K.;
- Zubair, Abba C.;
- Quiñones-Hinojosa, Alfredo;
- Kanekiyo, Takahisa
Publication type:
Article

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