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Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein.
- Published in:
- Biochemical Society Transactions, 2024, v. 52, n. 1, p. 301, doi. 10.1042/BST20230596
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- Publication type:
- Article
Tau here, tau there, tau almost everywhere: Clarifying the distribution of tau in the adult CNS.
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- Cytoskeleton, 2024, v. 81, n. 1, p. 107, doi. 10.1002/cm.21820
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- Publication type:
- Article
Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse.
- Published in:
- Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1265151
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- Publication type:
- Article
Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons.
- Published in:
- Molecular Neurobiology, 2023, v. 60, n. 6, p. 3423, doi. 10.1007/s12035-023-03281-3
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- Publication type:
- Article
Evaluating the Utility of Existing Plasma Biomarkers in a Clinical Patient Cohort.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.069312
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- Publication type:
- Article
Plasma phospho‐tau predicts differences in white matter microstructural complexity and cognition in non‐demented older adults.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.064157
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- Publication type:
- Article
Seeding human tau knock‐in neurons with human derived pathological tau results in the formation of pathogenic conformations of tau.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.068065
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- Publication type:
- Article
Mitochondrial oxidative stress contributes to the pathological aggregation and accumulation of tau oligomers in Alzheimer's disease.
- Published in:
- Human Molecular Genetics, 2022, v. 31, n. 15, p. 2498, doi. 10.1093/hmg/ddab363
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- Publication type:
- Article
Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy.
- Published in:
- Aging Cell, 2022, v. 21, n. 7, p. 1, doi. 10.1111/acel.13615
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- Publication type:
- Article
EFhd2 brain interactome reveals its association with different cellular and molecular processes.
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- Journal of Neurochemistry, 2021, v. 159, n. 6, p. 992, doi. 10.1111/jnc.15517
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- Publication type:
- Article
Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism.
- Published in:
- Journal of Neuroscience, 2021, v. 41, n. 45, p. 9431, doi. 10.1523/JNEUROSCI.1914-20.2021
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- Publication type:
- Article
Clioquinol Decreases Levels of Phosphorylated, Truncated, and Oligomerized Tau Protein.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 12063, doi. 10.3390/ijms222112063
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- Publication type:
- Article
Neuronal and Glial Distribution of Tau Protein in the Adult Rat and Monkey.
- Published in:
- Frontiers in Molecular Neuroscience, 2021, v. 13, p. N.PAG, doi. 10.3389/fnmol.2021.607303
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- Publication type:
- Article
Tau: A Signaling Hub Protein.
- Published in:
- Frontiers in Molecular Neuroscience, 2021, v. 13, p. N.PAG, doi. 10.3389/fnmol.2021.647054
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- Publication type:
- Article
Syk inhibitor reduces oligomeric tau associated with GSK3β inactivation and autophagy activation: Molecular and cell biology/tau.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042633
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- Publication type:
- Article
Clioquinol reduces tau phosphorylation and oligomerization: Molecular and cell biology/tau.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044356
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- Publication type:
- Article
Tau is not necessary for amyloid-β-induced synaptic and memory impairments.
- Published in:
- 2020
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- Publication type:
- journal article
Liquid-liquid phase separation induces pathogenic tau conformations in vitro.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16580-3
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- Publication type:
- Article
A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ<sub>42</sub> and tau-induced pathophysiological effects on long-term potentiation.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12029
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- Publication type:
- Article
Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain.
- Published in:
- Science Translational Medicine, 2019, v. 11, n. 523, p. 1, doi. 10.1126/scitranslmed.aao6545
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- Publication type:
- Article
EFhd2 Affects Tau Liquid–Liquid Phase Separation.
- Published in:
- Frontiers in Neuroscience, 2019, p. 1, doi. 10.1111/j.1471-4159.2008.05339.x
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- Publication type:
- Article
O5‐04‐01: TRIM46 KNOCKDOWN CAUSES NEURONAL TAU REDISTRIBUTION AND INCREASES AXOSOMATIC TAU DIFFUSION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1622, doi. 10.1016/j.jalz.2019.06.4852
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- Publication type:
- Article
P3‐173: MICROARRAY ANALYSES REVEAL SENESCENCE‐ASSOCIATED GENE EXPRESSION IN ALZHEIMER'S DISEASE AND TRANSGENIC MOUSE MODELS WITH AMYLOID DEPOSITION OR TAUOPATHY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P996, doi. 10.1016/j.jalz.2019.06.3202
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- Publication type:
- Article
Pathogenic tau modifications occur in axons before the somatodendritic compartment in mossy fiber and Schaffer collateral pathways.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0675-9
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- Publication type:
- Article
P3‐181: THE INTERACTION BETWEEN TAU AND PROTEIN PHOSPHATASE 1 IS AFFECTED BY P301L MUTATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1136, doi. 10.1016/j.jalz.2018.06.1539
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- Publication type:
- Article
O3‐01‐03: TAU KINETICS IN NEURONS AND IN THE HUMAN CNS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1008, doi. 10.1016/j.jalz.2018.06.2772
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- Publication type:
- Article
Tau Phosphorylation is Impacted by Rare <italic>AKAP9</italic> Mutations Associated with Alzheimer Disease in African Americans.
- Published in:
- Journal of NeuroImmune Pharmacology, 2018, v. 13, n. 2, p. 254, doi. 10.1007/s11481-018-9781-x
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- Publication type:
- Article
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
- Published in:
- 2018
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- Publication type:
- corrected article
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
- Published in:
- 2018
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- Publication type:
- journal article
Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 3, p. 891, doi. 10.3390/ijms19030891
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- Publication type:
- Article
Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.
- Published in:
- Frontiers in Neuroscience, 2017, p. 1, doi. 10.3389/fnins.2017.00572
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- Publication type:
- Article
TAU-INDUCED NEURODEGENERATION IS MEDIATED BY RNA BINDING PROTEINS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P555, doi. 10.1016/j.jalz.2017.07.157
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- Publication type:
- Article
THE SUBCELLULAR LOCALIZATION OF TAU AND THE PROPERTIES OF MUTANT P301L TAU IN PRIMARY NEURON CULTURES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1293, doi. 10.1016/j.jalz.2017.06.1955
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- Publication type:
- Article
Aging and Parkinson's disease: Different sides of the same coin?
- Published in:
- 2017
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- Publication type:
- journal article
Novel Non-phosphorylated Serine 9/21 GSK3β/α Antibodies: Expanding the Tools for Studying GSK3 Regulation.
- Published in:
- Frontiers in Molecular Neuroscience, 2016, v. 9, p. 1, doi. 10.3389/fnmol.2016.00123
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- Publication type:
- Article
Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons.
- Published in:
- Scientific Reports, 2016, p. 34904, doi. 10.1038/srep34904
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- Publication type:
- Article
Differential oligomer formation and phosphatase-activating domain exposure in tau isoforms under reducing and oxidizing conditions in vitro.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P504, doi. 10.1016/j.jalz.2015.06.593
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- Publication type:
- Article
The Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-Hydroxydopamine Reveals Significant Upregulation of Regeneration-Associated Genes.
- Published in:
- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0127768
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- Publication type:
- Article
A Method for Combining RNAscope In Situ Hybridization with Immunohistochemistry in Thick Free-Floating Brain Sections and Primary Neuronal Cultures.
- Published in:
- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120120
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- Publication type:
- Article
Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases.
- Published in:
- Journal of Neuroscience, 2011, v. 31, n. 27, p. 9858, doi. 10.1523/JNEUROSCI.0560-11.2011
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- Publication type:
- Article
Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates.
- Published in:
- 2011
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- Publication type:
- review
Axonal Transport Defects in Neurodegenerative Diseases.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 41, p. 12776, doi. 10.1523/JNEUROSCI.3463-09.2009
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- Publication type:
- Article
Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys.
- Published in:
- Glia, 2008, v. 56, n. 11, p. 1199, doi. 10.1002/glia.20690
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- Publication type:
- Article
Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.
- Published in:
- Annals of Neurology, 2006, v. 60, n. 2, p. 264
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- Publication type:
- Article