Works by Kamp, Frits

Results: 18

Charting γ-secretase substrates by explainable AI.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60638-z

By:

Breimann, Stephan;
Kamp, Frits;
Basset, Gabriele;
Abou-Ajram, Claudia;
Güner, Gökhan;
Yanagida, Kanta;
Okochi, Masayasu;
Müller, Stephan A.;
Lichtenthaler, Stefan F.;
Langosch, Dieter;
Frishman, Dmitrij;
Steiner, Harald

Publication type:

Article

The Nicastrin ectodomain adopts a highly thermostable structure.

Published in:

Biological Chemistry, 2011, v. 392, n. 11, p. 995, doi. 10.1515/BC.2011.169

By:

Fluhrer, Regina;
Kamp, Frits;
Grammer, Gudula;
Nuscher, Brigitte;
Steiner, Harald;
Beyer, Klaus;
Haass, Christian

Publication type:

Article

Microbiota-derived short chain fatty acids modulate microglia and promote Ab plaque deposition.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.59826

By:

Colombo, Alessio Vittorio;
Sadler, Rebecca Katie;
Llovera, Gemma;
Singh, Vikramjeet;
Roth, Stefan;
Heindl, Steffanie;
Monasor, Laura Sebastian;
Verhoeven, Aswin;
Peters, Finn;
Parhizkar, Samira;
Kamp, Frits;
Gomez de Aguero, Mercedes;
MacPherson, Andrew J.;
Winkler, Edith;
Herms, Jochen;
Benakis, Corinne;
Dichgans, Martin;
Steiner, Harald;
Giera, Martin;
Haass, Christian

Publication type:

Article

Bepridil and Amiodarone Simultaneously Target the Alzheimer's Disease β- and γ-Secretase via Distinct Mechanisms.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 26, p. 8974, doi. 10.1523/JNEUROSCI.1199-10.2010

By:

Mitterreiter, Stefan;
Page, Richard M.;
Kamp, Frits;
Hopson, Jessika;
Winkler, Edith;
Huy-Riem Ha;
Hamid, Runa;
Herms, Jochen;
Mayer, Thomas U.;
Nelson, Deborah J.;
Steiner, Harald;
Stahl, Tobias;
Zeitschel, Ulrike;
Roßner, Steffen;
Haass, Christian;
Lichtenthaler, Stefan F.

Publication type:

Article

Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 1, p. 99, doi. 10.1007/s00401-019-02082-0

By:

Nihei, Yoshihiro;
Mori, Kohji;
Werner, Georg;
Arzberger, Thomas;
Zhou, Qihui;
Khosravi, Barham;
Japtok, Julia;
Hermann, Andreas;
Sommacal, Andreas;
Weber, Markus;
Kamp, Frits;
Nuscher, Brigitte;
Edbauer, Dieter;
Haass, Christian

Publication type:

Article

Inhibition of amyloid-β plaque formation by α-synuclein.

Published in:

Nature Medicine, 2015, v. 21, n. 7, p. 802, doi. 10.1038/nm.3885

By:

Bachhuber, Teresa;
Katzmarski, Natalie;
McCarter, Joanna F;
Loreth, Desiree;
Tahirovic, Sabina;
Kamp, Frits;
Abou-Ajram, Claudia;
Nuscher, Brigitte;
Serrano-Pozo, Alberto;
Müller, Alexandra;
Prinz, Marco;
Steiner, Harald;
Hyman, Bradley T;
Haass, Christian;
Meyer-Luehmann, Melanie

Publication type:

Article

Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein.

Published in:

2018

By:

Spadaro, Melania;
Winklmeier, Stephan;
Beltrán, Eduardo;
Macrini, Caterina;
Höftberger, Romana;
Schuh, Elisabeth;
Thaler, Franziska S.;
Gerdes, Lisa Ann;
Laurent, Sarah;
Gerhards, Ramona;
Brändle, Simone;
Dornmair, Klaus;
Breithaupt, Constanze;
Krumbholz, Markus;
Moser, Markus;
Krishnamoorthy, Gurumoorthy;
Kamp, Frits;
Jenne, Dieter;
Hohlfeld, Reinhard;
Kümpfel, Tania

Publication type:

journal article

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.

Published in:

EMBO Journal, 2010, v. 29, n. 20, p. 3571, doi. 10.1038/emboj.2010.223

By:

Kamp, Frits;
Exner, Nicole;
Lutz, Anne Kathrin;
Wender, Nora;
Hegermann, Jan;
Brunner, Bettina;
Nuscher, Brigitte;
Bartels, Tim;
Giese, Armin;
Beyer, Klaus;
Eimer, Stefan;
Winklhofer, Konstanze F.;
Haass, Christian

Publication type:

Article

Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism.

Published in:

2003

By:

Kamp, Frits;
Kizilbash, Nadeem;
Corkey, Barbara E.;
Berggren, Per-Olof;
Hamilton, James A.

Publication type:

journal article

How Are Free Fatty Acids Transported in Membranes?

Published in:

Diabetes, 1999, v. 48, n. 12, p. 2255, doi. 10.2337/diabetes.48.12.2255

By:

Hamilton, James A.;
Kamp, Frits

Publication type:

Article

Fatty acid transport.

Published in:

Journal of Molecular Neuroscience, 2001, v. 16, n. 2/3, p. 99, doi. 10.1385/JMN:16:2-3:99

By:

Hamilton, James;
Johnson, Rebecca;
Corkey, Barbara;
Kamp, Frits

Publication type:

Article

Modelling Ser129 Phosphorylation Inhibits Membrane Binding of Pore-Forming Alpha-Synuclein Oligomers.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098906

By:

Nübling, Georg Sebastian;
Levin, Johannes;
Bader, Benedikt;
Lorenzl, Stefan;
Hillmer, Andreas;
Högen, Tobias;
Kamp, Frits;
Giese, Armin

Publication type:

Article

Single-Channel Electrophysiology Reveals a Distinct and Uniform Pore Complex Formed by α-Synuclein Oligomers in Lipid Membranes.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042545

By:

Schmidt, Felix;
Levin, Johannes;
Kamp, Frits;
Kretzschmar, Hans;
Giese, Armin;
Bötzel, Kai;
Tsien, Joe Z.

Publication type:

Article

The Glycosylation Site of Myelin Oligodendrocyte Glycoprotein Affects Autoantibody Recognition in a Large Proportion of Patients.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01189

By:

Marti Fernandez, Iris;
Macrini, Caterina;
Krumbholz, Markus;
Hensbergen, Paul J.;
Hipgrave Ederveen, Agnes L.;
Winklmeier, Stephan;
Vural, Atay;
Kurne, Asli;
Jenne, Dieter;
Kamp, Frits;
Gerdes, Lisa Ann;
Hohlfeld, Reinhard;
Wuhrer, Manfred;
Kümpfel, Tania;
Meinl, Edgar

Publication type:

Article

A stable G-quadruplex within the ADAM10 5'-UTR is involved in translational repression of ADAM10

Published in:

2011

By:

Lammich, Sven;
Büll, Dominik;
Zilow, Sonja;
Kamp, Frits;
Nuscher, Brigitte;
Ludwig, Ann-Katrin;
Prinzen, Claudia;
Fahrenholz, Falk;
Haass, Christian

Publication type:

Abstract

Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol.

Published in:

Molecules, 2019, v. 24, n. 13, p. 2353, doi. 10.3390/molecules24132353

By:

Junker, Julia;
Chong, Isabelle;
Kamp, Frits;
Steiner, Harald;
Giera, Martin;
Müller, Christoph;
Bracher, Franz;
Yaoita, Yasunori

Publication type:

Article

Reduced hn RNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition.

Published in:

EMBO Reports, 2016, v. 17, n. 9, p. 1314, doi. 10.15252/embr.201541724

By:

Mori, Kohji;
Nihei, Yoshihiro;
Arzberger, Thomas;
Zhou, Qihui;
Mackenzie, Ian R;
Hermann, Andreas;
Hanisch, Frank;
Kamp, Frits;
Nuscher, Brigitte;
Orozco, Denise;
Edbauer, Dieter;
Haass, Christian

Publication type:

Article

Alpha-synuclein fragments trigger distinct aggregation pathways.

Published in:

Cell Death & Disease, 2020, v. 11, n. 2, p. 1, doi. 10.1038/s41419-020-2285-7

By:

Chakroun, Tasnim;
Evsyukov, Valentin;
Nykänen, Niko-Petteri;
Höllerhage, Matthias;
Schmidt, Andreas;
Kamp, Frits;
Ruf, Viktoria C.;
Wurst, Wolfgang;
Rösler, Thomas W.;
Höglinger, Günter U.

Publication type:

Article