Works by Kalinowski, Danuta

Results: 20

Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: Application to a pilot pharmacokinetic study in rats.

Published in:

Biomedical Chromatography, 2014, v. 28, n. 5, p. 621, doi. 10.1002/bmc.3080

By:

Stariat, Ján;
Suprunová, Vlasta;
Roh, Jaroslav;
Šesták, Vít;
Eisner, Tomáš;
Filipský, Tomáš;
Mladěnka, Přemysl;
Nobilis, Milan;
Šimůnek, Tomáš;
Klimeš, Jiří;
Kalinowski, Danuta S.;
Richardson, Des R.;
Kovaříková, Petra

Publication type:

Article

Investigating the Spectrum of Biological Activity of Ring-Substituted Salicylanilides and Carbamoylphenylcarbamates.

Published in:

Molecules, 2010, v. 15, n. 11, p. 8122, doi. 10.3390/molecules15118122

By:

Otevrel, Jan;
Mandelova, Zuzana;
Pesko, Matus;
Jiahui Guo;
Kralova, Katarina;
Sersen, Frantisek;
Vejsova, Marcela;
Kalinowski, Danuta S.;
Kovacevic, Zaklina;
Coffey, Aidan;
Csollei, Jozef;
Richardson, Des R.;
Jampilek, Josef

Publication type:

Article

Antitumor activity and mechanism of action of the iron chelator, Dp44mT, against leukemic cells.

Published in:

American Journal of Hematology, 2009, v. 84, n. 3, p. 170, doi. 10.1002/ajh.21350

By:

Noulsri, Egarit;
Richardson, Des R.;
Lerdwana, Surada;
Fucharoen, Suthat;
Yamagishi, Tetsuo;
Kalinowski, Danuta S.;
Pattanapanyasat, Kovit

Publication type:

Article

Novel SPME fibers based on a plastic support for determination of plasma protein binding of thiosemicarbazone metal chelators: a case example of DpC, an anti-cancer drug that entered clinical trials.

Published in:

Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 11, p. 2383, doi. 10.1007/s00216-019-01681-w

By:

Reimerová, Petra;
Stariat, Ján;
Bavlovič Piskáčková, Hana;
Jansová, Hana;
Roh, Jaroslav;
Kalinowski, Danuta S.;
Macháček, Miloslav;
Šimůnek, Tomáš;
Richardson, Des R.;
Štěrbová-Kovaříková, Petra

Publication type:

Article

Identification of in vitro metabolites of the novel anti-tumor thiosemicarbazone, DpC, using ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry.

Published in:

Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 5, p. 1651, doi. 10.1007/s00216-012-6562-x

By:

Stariat, Ján;
Kovaříková, Petra;
Kučera, Radim;
Klimeš, Jiří;
Kalinowski, Danuta;
Richardson, Des;
Ketola, Raimo

Publication type:

Article

LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT.

Published in:

Analytical & Bioanalytical Chemistry, 2012, v. 403, n. 1, p. 309, doi. 10.1007/s00216-012-5766-4

By:

Stariat, Ján;
Šesták, Vít;
Vávrová, Kateřina;
Nobilis, Milan;
Kollárová, Zuzana;
Klimeš, Jiří;
Kalinowski, Danuta;
Richardson, Des;
Kovaříková, Petra

Publication type:

Article

Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics.

Published in:

Metallomics, 2016, v. 8, n. 9, p. 874, doi. 10.1039/c6mt00105j

By:

Park, Kyung Chan;
Fouani, Leyla;
Jansson, Patric J.;
Wooi, Danson;
Sahni, Sumit;
Lane, Darius J. R.;
Palanimuthu, Duraippandi;
Lok, Hiu Chuen;
Kovačević, Zaklina;
Huang, Michael L. H.;
Kalinowski, Danuta S.;
Richardson, Des R.

Publication type:

Article

Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia.

Published in:

Clinical Science, 2016, v. 130, n. 11, p. 853, doi. 10.1042/CS20160072

By:

Chiang, Shannon;
Kovacevic, Zaklina;
Sahni, Sumit;
Lane, Darius J. R.;
Merlot, Angelica M.;
Kalinowski, Danuta S.;
Huang, Michael L.-H.;
Richardson, Des R.

Publication type:

Article

Letter to the Editor: "Analysis of the Interaction of Dp44mT with Human Serum Albumin and Calf Thymus DNA Using Molecular Docking and Spectroscopic Techniques".

Published in:

2016

By:

Merlot, Angelica M.;
Sahni, Sumit;
Lane, Darius J. R.;
Richardson, Vera;
Huang, Michael L. H.;
Kalinowski, Danuta S.;
Richardson, Des R.

Publication type:

Letter to the Editor

PCTH: A Novel Orally Active Chelator for the Treatment of Iron Overload Disease.

Published in:

Hemoglobin, 2006, v. 30, n. 1, p. 93, doi. 10.1080/03630260500455367

By:

Lovejoy, David B.;
Kalinowski, Danuta;
Bernhardt, Paul V.;
Richardson, Des R.

Publication type:

Article

The redox-active, anti-cancer drug Dp44mT inhibits T-cell activation and CD25 through a copper-dependent mechanism.

Published in:

Redox Report, 2013, v. 18, n. 2, p. 48, doi. 10.1179/1351000213Y.0000000041

By:

Kalinowski, Danuta S.;
Jansson, Patric J.;
Kovacevic, Zaklina;
Richardson, Des R.

Publication type:

Article

Development of an LC–MS/MS method for analysis of interconvertible Z/E isomers of the novel anticancer agent, Bp4eT.

Published in:

Analytical & Bioanalytical Chemistry, 2010, v. 397, n. 1, p. 161, doi. 10.1007/s00216-009-3448-7

By:

Stariat, Ján;
Kovaříková, Petra;
Klimeš, Jiří;
Kalinowski, Danuta S.;
Richardson, Des R.

Publication type:

Article

Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2008, v. 13, n. 1, p. 107, doi. 10.1007/s00775-007-0300-4

By:

Bernhardt, Paul V.;
Wilson, Gregory J.;
Sharpe, Philip C.;
Kalinowski, Danuta S.;
Richardson, Des R.

Publication type:

Article

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139929

By:

Potůčková, Eliška;
Roh, Jaroslav;
Macháček, Miloslav;
Sahni, Sumit;
Stariat, Ján;
Šesták, Vít;
Jansová, Hana;
Hašková, Pavlína;
Jirkovská, Anna;
Vávrová, Kateřina;
Kovaříková, Petra;
Kalinowski, Danuta S.;
Richardson, Des R.;
Šimůnek, Tomáš

Publication type:

Article

Structure-Activity Relationships of Novel Salicylaldehyde Isonicotinoyl Hydrazone (SIH) Analogs: Iron Chelation, Anti-Oxidant and Cytotoxic Properties.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112059

By:

Potůčková, Eliška;
Hrušková, Kateřina;
Bureš, Jan;
Kovaříková, Petra;
Špirková, Iva A.;
Pravdíková, Kateřina;
Kolbabová, Lucie;
Hergeselová, Tereza;
Hašková, Pavlína;
Jansová, Hana;
Macháček, Miloslav;
Jirkovská, Anna;
Richardson, Vera;
Lane, Darius J. R.;
Kalinowski, Danuta S.;
Richardson, Des R.;
Vávrová, Kateřina;
Šimůnek, Tomáš

Publication type:

Article

Exploring the Anti-Cancer Activity of Novel Thiosemicarbazones Generated through the Combination of Retro-Fragments: Dissection of Critical Structure-Activity Relationships.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110291

By:

Serda, Maciej;
Kalinowski, Danuta S.;
Rasko, Nathalie;
Potůčková, Eliška;
Mrozek-Wilczkiewicz, Anna;
Musiol, Robert;
Małecki, Jan G.;
Sajewicz, Mieczysław;
Ratuszna, Alicja;
Muchowicz, Angelika;
Gołąb, Jakub;
Šimůnek, Tomáš;
Richardson, Des R.;
Polanski, Jaroslaw

Publication type:

Article

Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected Iron-Chelating Agents and Clinically Used Anti-Neoplastic Drugs.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088754

By:

Potuckova, Eliska;
Jansova, Hana;
Machacek, Miloslav;
Vavrova, Anna;
Haskova, Pavlina;
Tichotova, Lucie;
Richardson, Vera;
Kalinowski, Danuta S.;
Richardson, Des R.;
Simunek, Tomas

Publication type:

Article

The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxidant Defense, Autophagy, and Apoptosis.

Published in:

Oxidative Medicine & Cellular Longevity, 2019, p. 1, doi. 10.1155/2019/6392763

By:

Huang, Michael L.-H.;
Chiang, Shannon;
Kalinowski, Danuta S.;
Bae, Dong-Hun;
Sahni, Sumit;
Richardson, Des R.

Publication type:

Article

The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms.

Published in:

Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0330-x

By:

Zhu-Ling Guo;
Richardson, Des R.;
Kalinowski, Danuta S.;
Kovacevic, Zaklina;
Tan-Un, Kian Cheng;
Chan, Godfrey Chi-Fung

Publication type:

Article

Unraveling the mysteries of serum albumin—more than just a serum protein.

Published in:

Frontiers in Physiology, 2014, v. 5, p. 1, doi. 10.3389/fphys.2014.00299

By:

Merlot, Angelica M.;
Kalinowski, Danuta S.;
Richardson, Des R.

Publication type:

Article