Works by Kahn, C. R.

Results: 43

Male Brown Fat–Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity.

Published in:

Endocrinology, 2018, v. 159, n. 1, p. 323, doi. 10.1210/en.2017-00738

By:

Viana-Huete, Vanesa;
Guillén, Carlos;
García, Gema;
Fernández, Silvia;
García-Aguilar, Ana;
Kahn, C R;
Benito, Manuel

Publication type:

Article

Insulin-receptor antibodies mimic a late insulin effect.

Published in:

Nature, 1979, v. 280, n. 5722, p. 500, doi. 10.1038/280500a0

By:

VAN OBBERGHEN, E.;
SPOONER, P. M.;
KAHN, C. R.;
CHERNICK, S. S.;
GARRISON, M. M.;
KARLSSON, F. A.;
GRUNFELD, C.

Publication type:

Article

Insulin Resistance: A Look at the Role of Insulin Receptor Kinase.

Published in:

Diabetic Medicine, 1988, v. 5, n. 7, p. 621, doi. 10.1111/j.1464-5491.1988.tb01069.x

By:

Reddy, S. S.-K.;
Kahn, C. R.

Publication type:

Article

The PI3K regulatory subunits p55α and p50α regulate cell death in vivo.

Published in:

Cell Death & Differentiation, 2014, v. 21, n. 9, p. 1442, doi. 10.1038/cdd.2014.59

By:

Pensa, S;
Neoh, K;
Resemann, H K;
Kreuzaler, P A;
Abell, K;
Clarke, N J;
Reinheckel, T;
Kahn, C R;
Watson, C J

Publication type:

Article

Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.

Published in:

1990

By:

Warram, James H.;
Martin, Blaise C.;
Krolewski, Andrzej S.;
Soeldner, J. Stuart;
Kahn, C. Ronald;
Warram, J H;
Martin, B C;
Krolewski, A S;
Soeldner, J S;
Kahn, C R

Publication type:

journal article

Resistance to Apoptosis in Preadipocytes with Knockout of Both the Insulin and IGF-1 Receptors.

Published in:

Diabetes, 2007, v. 56, p. A511

By:

Boucher, Jeremie;
Macotela, Yazmin;
Kriauciunas, Kristina;
Kahn, C. R.

Publication type:

Article

PPARγ1 Stimulates Uptake and Oxidation of Fatty Acid in Myocytes.

Published in:

Diabetes, 2007, v. 56, p. A399

By:

Yao, Jianrong;
Hu, Shanming;
Kahn, C. R.;
Spector, Arthur A.;
Norris, Andrew W.

Publication type:

Article

Acute Ablation of ARNT/HIF1β in Liver Results in Elevated Gluconeogenesis, Hypoketonemia, and Dyslipidemia.

Published in:

Diabetes, 2007, v. 56, p. A393

By:

Wang, Xiaohui L.;
Suzuki, Ryo;
Patti, Mary-Elizabeth;
Goldfine, Allison;
Gonzalez, Frank J.;
Kahn, C. R.

Publication type:

Article

Impaired Insulin Signaling Is Associated with Decreased Incidence of Experimental Skin Cancer.

Published in:

Diabetes, 2007, v. 56, p. A347

By:

Russ, Jenny;
Weingarten, Galina;
Takeda, Junji;
Kahn, C. R.;
Wertheimer, Efrat

Publication type:

Article

Gender and Depot Differences in Adipocyte Insulin Sensitivity and the Sexual Dimorphism of Insulin Resistance.

Published in:

Diabetes, 2007, v. 56, p. A338

By:

Macotela, Yazmin;
Boucher, Jeremie;
Tran, Thien T.;
Gesta, Stephane;
Kahn, C. R.

Publication type:

Article

Pancreatic Function in Carboxyl-Ester Lipase Knockout Mice.

Published in:

Diabetes, 2007, v. 56, p. A294

By:

Vesterhus, Mette;
Rader, Helge;
Kurpad, Amarnath;
Kulkarni, Rohit N.;
Kahn, C. R.;
Njolstad, Pal R.

Publication type:

Article

DR1, A Novel Potential Regulator of Gene Expression in Diabetes and Insulin Resistance.

Published in:

Diabetes, 2007, v. 56, p. A287

By:

Jing, Enxuan;
Crunkhorn, Sarah;
Leykin, Igor;
Norris, Andrew W.;
Kahn, C. R.

Publication type:

Article

Loss of Insulin Signaling in Vascular Endothelium Accelerates Atherosclerosis in Apolipoprotein E Knockout Mice.

Published in:

Diabetes, 2007, v. 56, p. A55

By:

Rask-Madsen, Christian;
Vecchia, Kim Della;
Wu, I-Hsien;
Scott, Josh A.;
Arikawa, Emi;
Matsumoto, Motonobu;
Clermont, Allen C.;
Polivy, Lindsey;
Sotiropoulos, Konstantinos B.;
Kahn, C. R.;
King, George L.

Publication type:

Article

Role Of Class IA PI 3-Kinase In Pancreatic β Cells.

Published in:

Diabetes, 2007, v. 56, p. A28

By:

Kaneko, Kazuma;
Ueki, Kohjiro;
Hashimoto, Shinji;
Awazawa, Motoharu;
Ji Luo;
Cantley, Lewis C.;
Kahn, C. R.;
Tobe, Kazuyuki;
Kadowaki, Takashi

Publication type:

Article

A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes.

Published in:

2000

By:

Mauvais-Jarvis, Franck;
Virkamaki, Antti;
Michael, M. Dodson;
Winnay, Jonathon N.;
Zisman, Ariel;
Kulkarni, Rohit N.;
Kahn, C. Ronald;
Mauvais-Jarvis, F;
Virkamaki, A;
Michael, M D;
Winnay, J N;
Zisman, A;
Kulkarni, R N;
Kahn, C R

Publication type:

journal article

Heterozygous expansion of the GAA tract of the X25/frataxin gene is associated with insulin resistance in humans.

Published in:

2000

By:

Hebinck, Judith;
Hardt, Cornelia;
Schols, Ludger;
Vorgerd, Matthias;
Briedigkeit, Lutz;
Kahn, C. Ronald;
Ristow, Michael;
Hebinck, J;
Hardt, C;
Schöls, L;
Vorgerd, M;
Briedigkeit, L;
Kahn, C R;
Ristow, M

Publication type:

journal article

Insulin signaling in insulin receptor substrate (IRS)-1-deficient brown adipocytes: requirement of IRS-1 for lipid synthesis.

Published in:

1999

By:

Valverde, Angela M.;
Kahn, C. Ronald;
Benito, Manuel;
Valverde, A M;
Kahn, C R;
Benito, M

Publication type:

journal article

Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice.

Published in:

1999

By:

Gazdag, Annie C.;
Dumke, Charles L.;
Kahn, C. Ronald;
Cartee, Gregory D.;
Gazdag, A C;
Dumke, C L;
Kahn, C R;
Cartee, G D

Publication type:

journal article

Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle.

Published in:

1999

By:

Patti, Mary-Elizabeth;
Virkamaki, Antti;
Landaker, Edwin J.;
Kahn, C. Ronald;
Yki-Jarvinen, Hannele;
Patti, M E;
Virkamäki, A;
Landaker, E J;
Kahn, C R;
Yki-Järvinen, H

Publication type:

journal article

Alterations in skeletal muscle gene expression of ob/ob mice by mRNA differential display.

Published in:

1998

By:

Vicent, D;
Piper, M;
Gammeltoft, S;
Maratos-Flier, E;
Kahn, C R

Publication type:

journal article

An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene.

Published in:

1998

By:

Ristow, Michael;
Giannakidou, Eleni;
Ristow, M;
Giannakidou, E;
Hebinck, J;
Busch, K;
Vorgerd, M;
Kotzka, J;
Knebel, B;
Mueller-Berghaus, J;
Epplen, C;
Pfeiffer, A;
Kahn, C R;
Doria, A;
Krone, W;
Mueller-Wieland, D

Publication type:

journal article

Effects of insulin-sensitising agents in mice with hepatic insulin resistance S.E. Cohen et al.: Insulin sensitisers’ effects in LIRKO mice.

Published in:

Diabetologia, 2004, v. 47, n. 3, p. 407, doi. 10.1007/s00125-003-1320-4

By:

Cohen, S. E.;
Tseng, Y.-H.;
Michael, M. D.;
Kahn, C. R.

Publication type:

Article

An arginine to cysteine<sup>252</sup> mutation in insulin receptors from a patient with severe insulin resistance inhibits receptor internalisation but preserves signalling events I. Hamer et al.: <sup>252</sup>Cys mutant IR.

Published in:

Diabetologia, 2002, v. 45, n. 5, p. 657, doi. 10.1007/s00125-002-0798-5

By:

Hamer, I.;
Foti, M.;
Emkey, R.;
Cordier-Bussat, M.;
Philippe, J.;
de Meyts, P.;
Maeder, C.;
Kahn, C. R.;
Carpentier, J.-L.

Publication type:

Article

Metabolically healthy and unhealthy obese - the 2013 Stock Conference report.

Published in:

Obesity Reviews, 2014, v. 15, n. 9, p. 697, doi. 10.1111/obr.12199

By:

Samocha-Bonet, D.;
Dixit, V. D.;
Kahn, C. R.;
Leibel, R. L.;
Lin, X.;
Nieuwdorp, M.;
Pietiläinen, K. H.;
Rabasa-Lhoret, R.;
Roden, M.;
Scherer, P. E.;
Klein, S.;
Ravussin, E.

Publication type:

Article

The role of insulin and IGF-1 signaling in longevity.

Published in:

Cellular & Molecular Life Sciences, 2005, v. 62, n. 3, p. 320, doi. 10.1007/s00018-004-4297-y

By:

Katic, M.;
Kahn, C. R.

Publication type:

Article

Genetically programmed selective islet beta-cell loss in diabetic subjects with Wolfram's syndrome.

Published in:

1989

By:

Karasik, A;
O'Hara, C;
Srikanta, S;
Swift, M;
Soeldner, J S;
Kahn, C R;
Herskowitz, R D

Publication type:

journal article

Dietary carbohydrate, a Big Mac, and insulin requirements in type I diabetes.

Published in:

1988

By:

Vlachokosta, Frederika V.;
Piper, Cheryl M.;
Gleason, Ray;
Kinzel, Laura;
Kahn, C. Ronald;
Vlachokosta, F V;
Piper, C M;
Gleason, R;
Kinzel, L;
Kahn, C R

Publication type:

journal article

Risk of proliferative diabetic retinopathy in juvenile-onset type I diabetes: a 40-yr follow-up study.

Published in:

1986

By:

KROLEWSKI, A. S.;
WARRAM, J. H.;
RAND, L. I.;
CHRISTLIEB, A. R.;
BUSICK, E. J.;
KAHN, C. R.

Publication type:

journal article

Trinucleotide repeats at the rad locus. Allele distributions in NIDDM and mapping to a 3-cM region on chromosome 16q.

Published in:

1995

By:

Doria, A;
Caldwell, J S;
Ji, L;
Reynet, C;
Rich, S S;
Weremowicz, S;
Morton, C C;
Warram, J H;
Kahn, C R;
Krolewski, A S

Publication type:

journal article

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes.

Published in:

1994

By:

Kahn, C R

Publication type:

journal article

Human skeletal muscle insulin receptor substrate-1. Characterization of the cDNA, gene, and chromosomal localization.

Published in:

1993

By:

Araki, Eiichi;
Xiao-Jian Sun;
Yitao Zhang;
Yang-Feng, Teresa L.;
White, Moris F.;
Kahn, C. Ronald;
Araki, E;
Sun, X J;
Haag, B L 3rd;
Chuang, L M;
Zhang, Y;
Yang-Feng, T L;
White, M F;
Kahn, C R

Publication type:

journal article

Coordinate phosphorylation of insulin-receptor kinase and its 175,000-Mr endogenous substrate in rat hepatocytes.

Published in:

1991

By:

Okamoto, Motozumi;
Karasik, Avraham;
White, Morris F.;
Kahn, C. Ronald;
Okamoto, M;
Karasik, A;
White, M F;
Kahn, C R

Publication type:

journal article

Insulin-receptor gene and its expression in patients with insulin resistance.

Published in:

1989

By:

Muller-Wieland, Dirk;
Taub, Rebecca;
Tewari, Dinesh S.;
Kriauciunas, Kristina M.;
Sethu, S.;
Reddy, K.;
Kahn, C. Ronald;
Muller-Wieland, D;
Taub, R;
Tewari, D S;
Kriauciunas, K M;
Kahn, C R

Publication type:

journal article

Determinants of IDDM and perinatal mortality in children of diabetic mothers.

Published in:

1988

By:

Warram, James H.;
Krolewski, Andrzej S.;
Kahn, C. Ronald;
Warram, J H;
Krolewski, A S;
Kahn, C R

Publication type:

journal article

Effects of heparin on insulin binding and biological activity.

Published in:

1987

By:

Kriauciunas, Kristina M.;
Grigorescu, Florin;
Kahn, C. Ronald;
Kriauciunas, K M;
Grigorescu, F;
Kahn, C R

Publication type:

journal article

Characterization of binding and phosphorylation defects of erythrocyte insulin receptors in the type A syndrome of insulin resistance.

Published in:

1986

By:

Grigorescu, Florin;
Flier, Jeffrey S.;
Kahn, C. Ronald;
Grigorescu, F;
Flier, J S;
Kahn, C R

Publication type:

journal article

Visualization of the insulin receptor by immunoblotting.

Published in:

1984

By:

Maron, Ruth;
Kahn, C. Ronald;
Jacobs, Steven;
Fujita-Yamaguchi, Y.;
Maron, R;
Kahn, C R;
Jacobs, S

Publication type:

journal article

Processing of insulin by bovine endothelial cells in culture. Internalization without degradation.

Published in:

1984

By:

Jialal, Ishwarlal;
King, George L.;
Buchwald, Sherry;
Kahn, C. Ronald;
Crettaz, Marco;
Jialal, I;
King, G L;
Buchwald, S;
Kahn, C R;
Crettaz, M

Publication type:

journal article

Insulin receptor regulation and desensitization in rat hepatoma cells. Concomitant changes in receptor number and in binding affinity.

Published in:

1984

By:

Crettaz, Marco;
Kahn, C. Ronald;
Crettaz, M;
Kahn, C R

Publication type:

journal article

Photoreactive insulin derivatives. Comparison of biologic activity and labeling properties of three analogues in isolated rat adipocytes.

Published in:

1982

By:

Wang, C C;
Hedo, J A;
Kahn, C R;
Saunders, D T;
Thamm, P;
Brandenburg, D

Publication type:

journal article

Insulin activates glycogen synthase in cultured human fibroblasts.

Published in:

1980

By:

Podskalny, Judith M.;
Kahn, C. Ronlad;
Podskalny, J M;
Kahn, C R

Publication type:

journal article

The insulin receptor and insulin of the Atlantic hagfish. Extraordinary conservation of binding specificity and negative cooperativity in the most primitive vertebrate.

Published in:

1979

By:

Muggeo, M;
Van Obberghen, E;
Kahn, C R;
Roth, J;
Ginsberg, B H;
De Meyts, B H;
Emdin, S O;
Falkmer, S

Publication type:

journal article

The Insulin Receptor and Insulin of the Atlantic Hagfish.

Published in:

Diabetes, 1979, v. 28, n. 3, p. 175, doi. 10.2337/diab.28.3.175

By:

Muggeo, M.;
Van Obberghen, E.;
Kahn, C. R.;
Roth, J.;
Ginsberg, B. H.;
De Meyts, P.;
Emdin, S. O.;
Falkmer, S.

Publication type:

Article