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Prominent microglial inclusions in transgenic mouse models of α-synucleinopathy that are distinct from neuronal lesions.
- Published in:
- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00993-8
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- Publication type:
- Article
Medin amyloid forms age‐associated aggregates in the brain vasculature and may contribute to cerebral β‐amyloidosis: Molecular and cell biology/APP/Abeta/amyloid.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042861
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- Publication type:
- Article
P4‐544: DEEP PROTEOME ANALYSIS IN CEREBROSPINAL FLUID OF MOUSE MODELS FOR NEURODEGENERATIVE DISEASES SUGGESTS A PANEL OF NOVEL BIOMARKERS RELATED TO MICROGLIA ACTIVATION.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1524, doi. 10.1016/j.jalz.2019.08.091
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- Publication type:
- Article
In vivo models of alpha-synuclein transmission and propagation.
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- Cell & Tissue Research, 2018, v. 373, n. 1, p. 183, doi. 10.1007/s00441-017-2730-9
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- Publication type:
- Article
How does parkin ligate ubiquitin to Parkinson's disease?
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- EMBO Reports, 2004, v. 5, n. 7, p. 681, doi. 10.1038/sj.embor.7400188
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- Publication type:
- Article
Attack on amyloid.
- Published in:
- 2003
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- Publication type:
- Report
Hyperphosphorylation and insolubility of a-synuclein in transgenic mouse oligodendrocytes.
- Published in:
- EMBO Reports, 2002, v. 3, n. 6, p. 583, doi. 10.1093/embo-reports/kvf109
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- Publication type:
- Article
Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy.
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- Nucleic Acids Research, 2017, v. 45, n. 5, p. 2797, doi. 10.1093/nar/gkw911
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- Publication type:
- Article
TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR.
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- Nucleic Acids Research, 2012, v. 40, n. 6, p. 2668, doi. 10.1093/nar/gkr1082
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- Publication type:
- Article
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28822-7
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- Publication type:
- Article
Seeding of cross linked alpha-synuclein oligomers in vitro and in vivo
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- 2010
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- Publication type:
- Abstract
Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model.
- Published in:
- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0364-x
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- Publication type:
- Article
Early fine motor impairment and behavioral dysfunction in (Thy‐1)‐h[A30P] alpha‐synuclein mice.
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- Brain & Behavior, 2018, v. 8, n. 3, p. 1, doi. 10.1002/brb3.915
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- Publication type:
- Article
α-Synuclein enhances histone H3 lysine-9 dimethylation and H3K9me2-dependent transcriptional responses.
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- Scientific Reports, 2016, p. 36328, doi. 10.1038/srep36328
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- Publication type:
- Article
FAS-Dependent Cell Death in α-Synuclein Transgenic Oligodendrocyte Models of Multiple System Atrophy.
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- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0055243
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- Publication type:
- Article
Impaired c-Fos and Polo-Like Kinase 2 Induction in the Limbic System of Fear-conditioned α-Synuclein Transgenic Mice.
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- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0050245
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- Publication type:
- Article
Screening for Novel LRRK2 Inhibitors Using a High- Throughput TR-FRET Cellular Assay for LRRK2 Ser935 Phosphorylation.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043580
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- Publication type:
- Article
Inhibition of TDP-43 Accumulation by Bis(thiosemicarbazonato)-Copper Complexes.
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- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042277
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- Publication type:
- Article
Neuropathology in Mice Expressing Mouse Alpha- Synuclein.
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- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024834
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- Publication type:
- Article
TDP-43-Mediated Neuron Loss In Vivo Requires RNA-Binding Activity.
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- PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012247
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- Publication type:
- Article
Reduced Basal Autophagy and Impaired Mitochondrial Dynamics Due to Loss of Parkinson's Disease-Associated Protein DJ-1.
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- PLoS ONE, 2010, v. 5, n. 2, p. 1, doi. 10.1371/journal.pone.0009367
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- Publication type:
- Article
Parkin Deficiency Delays Motor Decline and Disease Manifestation in a Mouse Model of Synucleinopathy.
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- PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006629
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- Publication type:
- Article
Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro.
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- Journal of Neuroscience Research, 1998, v. 52, n. 4, p. 483, doi. 10.1002/(SICI)1097-4547(19980515)52:4<483::AID-JNR12>3.0.CO;2-4
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- Publication type:
- Article
Physiology and Pathophysiology of α-Synuclein: Cell Culture and Transgenic Animal Models Based on a Parkinson's Disease-associated Protein.
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- Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 33, doi. 10.1111/j.1749-6632.2000.tb06902.x
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- Publication type:
- Article
Environmental Enrichment Prevents Transcriptional Disturbances Induced by Alpha-Synuclein Overexpression.
- Published in:
- Frontiers in Cellular Neuroscience, 2018, p. 1, doi. 10.3389/fncel.2018.00112
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- Publication type:
- Article
Loss-of-Function of Human PINK1 Results in Mitochondrial Pathology and Can Be Rescued by Parkin.
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- Journal of Neuroscience, 2007, v. 27, n. 45, p. 12413, doi. 10.1523/JNEUROSCI.0719-07.2007
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- Publication type:
- Article
α-Synuclein oligomers pump it up!
- Published in:
- EMBO Journal, 2015, v. 34, n. 19, p. 2385, doi. 10.15252/embj.201592770
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- Publication type:
- Article
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6.
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- EMBO Journal, 2010, v. 29, n. 1, p. 209, doi. 10.1038/emboj.2009.324
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- Publication type:
- Article
Exogenous α-synuclein induces toll-like receptor 4 dependent inflammatory responses in astrocytes.
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- BMC Neuroscience, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12868-015-0192-0
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- Publication type:
- Article
Exogenous α‑synuclein induces toll‑like receptor 4 dependent inflammatory responses in astrocytes.
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- BMC Neuroscience, 2015, v. 16, n. 1, p. 57, doi. 10.1186/s12868-015-0192-0
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- Publication type:
- Article
Parkinson’s disease: dopaminergic nerve cell model is consistent with experimental finding of increased extracellular transport of α-synuclein.
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- BMC Neuroscience, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2202-14-136
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- Publication type:
- Article
Parkinson's disease: dopaminergic nerve cell model is consistent with experimental finding of increased extracellular transport of α-synuclein.
- Published in:
- 2013
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- Publication type:
- journal article
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.
- Published in:
- Nature Cell Biology, 2010, v. 12, n. 2, p. 119, doi. 10.1038/ncb2012
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- Publication type:
- Article
Monitoring α-synuclein multimerization in vivo.
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- FASEB Journal, 2019, v. 33, n. 2, p. 2116, doi. 10.1096/fj.201800148RRR
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- Publication type:
- Article
Toll-like receptors 2 and 4 impair insulin-mediated brain activity by interleukin-6 and osteopontin and alter sleep architecture.
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- FASEB Journal, 2012, v. 26, n. 5, p. 1799, doi. 10.1096/fj.11-191023
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- Publication type:
- Article
Regulation of astrocyte inflammatory responses by the Parkinson's disease-associated gene DJ-1.
- Published in:
- FASEB Journal, 2009, v. 23, n. 8, p. 2478, doi. 10.1096/fj.08-125153
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- Publication type:
- Article
TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration.
- Published in:
- FEBS Journal, 2011, v. 278, n. 19, p. 3550, doi. 10.1111/j.1742-4658.2011.08258.x
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- Publication type:
- Article
Proteomics elucidating physiological and pathological functions of TDP‐43.
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- Proteomics, 2023, v. 23, n. 23/24, p. 1, doi. 10.1002/pmic.202200410
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- Publication type:
- Article
Pathological properties of the Parkinson’s disease-associated protein DJ-1 in α-synucleinopathies and tauopathies: relevance for multiple system atrophy and Pick’s disease.
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- Acta Neuropathologica, 2004, v. 107, n. 6, p. 489, doi. 10.1007/s00401-004-0834-2
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- Publication type:
- Article
Failure of diet-induced transcriptional adaptations in alpha-synuclein transgenic mice.
- Published in:
- Human Molecular Genetics, 2023, v. 32, n. 3, p. 450, doi. 10.1093/hmg/ddac205
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- Publication type:
- Article
The aggregation of alpha-synuclein is stimulated by FK506 binding proteins as shown by fluorescence correlation spectroscopy.
- Published in:
- FASEB Journal, 2006, v. 20, n. 3, p. 524, doi. 10.1096/fj.05-5126fje
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- Publication type:
- Article
Enhanced motivation to alcohol in transgenic mice expressing human α-synuclein.
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- Journal of Neurochemistry, 2017, v. 143, n. 3, p. 294, doi. 10.1111/jnc.14151
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- Publication type:
- Article
Diet-induced obesity accelerates the onset of terminal phenotypes in α-synuclein transgenic mice.
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- Journal of Neurochemistry, 2014, v. 131, n. 6, p. 848, doi. 10.1111/jnc.12813
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- Publication type:
- Article
Interferon-γ induces leucine-rich repeat kinase LRRK2 via extracellular signal-regulated kinase ERK5 in macrophages.
- Published in:
- Journal of Neurochemistry, 2014, v. 129, n. 6, p. 980, doi. 10.1111/jnc.12668
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- Publication type:
- Article
Monoclonal antibodies selective for α-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α-synuclein transgenic mice with the disease-causing A30P mutation.
- Published in:
- Journal of Neurochemistry, 2013, v. 126, n. 1, p. 131, doi. 10.1111/jnc.12175
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- Publication type:
- Article
Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion.
- Published in:
- Journal of Neurochemistry, 2013, v. 125, n. 2, p. 314, doi. 10.1111/jnc.12126
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- Publication type:
- Article
Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain.
- Published in:
- Journal of Neurochemistry, 2010, v. 114, n. 4, p. 1007, doi. 10.1111/j.1471-4159.2010.06832.x
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- Publication type:
- Article
Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.
- Published in:
- Journal of Neurochemistry, 2009, v. 111, n. 3, p. 703, doi. 10.1111/j.1471-4159.2009.06358.x
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- Publication type:
- Article
Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 15, p. 3975, doi. 10.1093/hmg/ddu112
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- Publication type:
- Article
Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 3, p. 767, doi. 10.1093/hmg/ddt467
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- Publication type:
- Article