Works by Kadurin, Ivan

Results: 8

ADAM17 Mediates Proteolytic Maturation of Voltage-Gated Calcium Channel Auxiliary α2δ Subunits, and Enables Calcium Current Enhancement.

Published in:

Function, 2022, v. 3, n. 3, p. 1, doi. 10.1093/function/zqac013

By:

Kadurin, Ivan;
Dahimene, Shehrazade;
Page, Karen M;
Ellaway, Joseph I J;
Chaggar, Kanchan;
Troeberg, Linda;
Nagase, Hideaki;
Dolphin, Annette C

Publication type:

Article

Biallelic CACNA2D1 loss-of-function variants cause early-onset developmental epileptic encephalopathy.

Published in:

2022

By:

Dahimene, Shehrazade;
Elsner, Leonie von;
Holling, Tess;
Mattas, Lauren S;
Pickard, Jess;
Lessel, Davor;
Pilch, Kjara S;
Kadurin, Ivan;
Pratt, Wendy S;
Zhulin, Igor B;
Dai, Hongzheng;
Hempel, Maja;
Ruzhnikov, Maura R Z;
Kutsche, Kerstin;
Dolphin, Annette C;
von Elsner, Leonie

Publication type:

journal article

LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α2δ-1 subunit.

Published in:

Scientific Reports, 2017, p. 43802, doi. 10.1038/srep43802

By:

Kadurin, Ivan;
Rothwell, Simon W.;
Lana, Beatrice;
Nieto-Rostro, Manuela;
Dolphin, Annette C.

Publication type:

Article

Thrombospondin-4 reduces binding affinity of [3H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed.

Published in:

Scientific Reports, 2016, p. 24531, doi. 10.1038/srep24531

By:

Lana, Beatrice;
Page, Karen M.;
Kadurin, Ivan;
Ho, Shuxian;
Nieto-Rostro, Manuela;
Dolphin, Annette C.

Publication type:

Article

Presynaptic HCN1 channels regulate CaV3.2 activity and neurotransmission at select cortical synapses.

Published in:

Nature Neuroscience, 2011, v. 14, n. 4, p. 478, doi. 10.1038/nn.2757

By:

Zhuo Huang;
Lujan, Rafael;
Kadurin, Ivan;
Uebele, Victor N.;
Renger, John J.;
Dolphin, Annette C.;
Shah, Mala M.

Publication type:

Article

The inhibition of functional expression of calcium channels by prion protein demonstrates competition with α2δ for GPI-anchoring pathways.

Published in:

Biochemical Journal, 2014, v. 458, n. 2, p. 365, doi. 10.1042/BJ20131405

By:

ALVAREZ-LAVIADA, Anita;
KADURIN, Ivan;
SENATORE, Assunta;
CHIESA, Roberto;
DOLPHIN, Annette C.

Publication type:

Article

Proteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.21143

By:

Kadurin, Ivan;
Ferron, Laurent;
Rothwell, Simon W.;
Meyer, James O.;
Douglas, Leon R.;
Bauer, Claudia S.;
Lana, Beatrice;
Margas, Wojciech;
Alexopoulos, Orpheas;
Nieto-Rostro, Manuela;
Pratt, Wendy S.;
Dolphin, Annette C.

Publication type:

Article

The Increased Trafficking of the Calcium Channel Subunit α2δ-1 to Presynaptic Terminals in Neuropathic Pain Is Inhibited by the α2δ Ligand Pregabalin.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 13, p. 4076, doi. 10.1523/JNEUROSCI.0356-09.2009

By:

Bauer, Claudia S.;
Nieto-Rostro, Manuela;
Rahman, Wahida;
Tran-Van-Minh, Alexandra;
Ferron, Laurent;
Douglas, Leon;
Kadurin, Ivan;
Ranjan, Yorain Sri;
Fernandez-Alacid, Laura;
Millar, Neil S.;
Dickenson, Anthony H.;
Lujan, Rafael;
Dolphin, Annette C.

Publication type:

Article

Works by Kadurin, Ivan

ADAM17 Mediates Proteolytic Maturation of Voltage-Gated Calcium Channel Auxiliary α2δ Subunits, and Enables Calcium Current Enhancement.

Biallelic CACNA2D1 loss-of-function variants cause early-onset developmental epileptic encephalopathy.

LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α<sub>2</sub>δ-1 subunit.

Thrombospondin-4 reduces binding affinity of [<sup>3</sup>H]-gabapentin to calcium-channel α<sub>2</sub>δ-1-subunit but does not interact with α<sub>2</sub>δ-1 on the cell-surface when co-expressed.

Presynaptic HCN1 channels regulate Ca<sub>V</sub>3.2 activity and neurotransmission at select cortical synapses.

The inhibition of functional expression of calcium channels by prion protein demonstrates competition with α<sub>2</sub>δ for GPI-anchoring pathways.

Proteolytic maturation of α<sub>2</sub>δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.

The Increased Trafficking of the Calcium Channel Subunit α<sub>2</sub>δ-1 to Presynaptic Terminals in Neuropathic Pain Is Inhibited by the α<sub>2</sub>δ Ligand Pregabalin.