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Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Genetic diversity promotes resilience in a mouse model of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2794, doi. 10.1002/alz.13753
- By:
- Publication type:
- Article
Sex and age dependent effects of gut microbiota manipulation in App<sup>SAA</sup> mouse model of Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083180
- By:
- Publication type:
- Article
Generation and screening of mouse models of ADRD with multiple genetic manipulations to model dementia with mixed brain pathologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083158
- By:
- Publication type:
- Article
Chromosome Y‐haplotype mediates cognitive resilience and differential expression of transposable elements in 5xFAD‐carrying AD‐BXD males.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082951
- By:
- Publication type:
- Article
Genetics and diet explain sex differences in glucose metabolism and cognitive function.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082683
- By:
- Publication type:
- Article
Not all regions are created equal: identifying regions and cell types associated with cognitive resilience in the AD‐BXD model population.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082599
- By:
- Publication type:
- Article
Investigating Dendritic Spine Morphology as a Mediator of Cognitive Outcomes in Aged Diversity Outbred Mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079832
- By:
- Publication type:
- Article
ApoE variant associated with cognitive resilience alters AD associated hyperexcitability in dentate granule neurons.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076851
- By:
- Publication type:
- Article
Leveraging systems biology approaches and single‐nucleus RNA‐seq to study sex differences in AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076877
- By:
- Publication type:
- Article
Leveraging systems biology approaches and single‐nucleus RNA‐seq to study sex differences in AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076877
- By:
- Publication type:
- Article
Early synaptic gene expression downregulation in the frontal cortex distinguishes Alzheimer's disease from normal aging in a genetically diverse mouse population.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.065931
- By:
- Publication type:
- Article
Evaluating the brain renin‐angiotensin system (RAS) and sex differences in pre‐clinical models of Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.063318
- By:
- Publication type:
- Article
Identification of Genetic Loci and Sex Differences Associated with Amyloid Burden Using the AD‐BXD Mouse Population.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.069391
- By:
- Publication type:
- Article
Single amino acid change in the receptor binding domain of mouse APOE results in altered protein dynamics and worsened AD‐related cognitive impairment.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.067225
- By:
- Publication type:
- Article
Cell‐type Specific Effects of AD Mutations on Hippocampal Intrinsic Firing Properties in Genetically Diverse Mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.068784
- By:
- Publication type:
- Article
Impact of background strains and diet on metabolic profile in mouse model of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067666
- By:
- Publication type:
- Article
Identification of transcriptional signatures of cognitive resilience using single nucleus RNA sequencing.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065947
- By:
- Publication type:
- Article
KDM6A expression is associated with a sex‐disease interaction in activated microglia.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065829
- By:
- Publication type:
- Article
Understanding comorbid metabolic dysfunctions in Alzheimer's disease using the AD‐BXDs.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.064808
- By:
- Publication type:
- Article
Identifying heritable brain networks that may confer cognitive reserve to Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.061672
- By:
- Publication type:
- Article
Brain‐wide spatial analysis reveals cell‐type‐specific genetic modifiers of Alzheimer's disease progression.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.061853
- By:
- Publication type:
- Article
Sex differences in the genetic architecture underlying resilience in AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055010
- By:
- Publication type:
- Article
High‐fat diet generally exacerbates, but is sometimes protective against, cognitive dysfunction in female AD mice depending on genetic background.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055013
- By:
- Publication type:
- Article
Disentangling the determinants of transposable element expression in cognitive aging and Alzheimer's disease deficits using the AD‐BXD mouse population.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053048
- By:
- Publication type:
- Article
APOE variant in the receptor binding domain confers cognitive resilience to familial Alzheimer's mutations and cell‐type specific gene expression changes in the hippocampus.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.051794
- By:
- Publication type:
- Article
Brain‐wide spatial analysis to identify region‐specific changes in cell composition associated with resilience to Alzheimer's disease in the AD‐BXD mouse population: Developing topics.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047613
- By:
- Publication type:
- Article
Mid‐life obesity and metabolic dysfunction in a genetically diverse mouse model of Alzheimer's disease: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044038
- By:
- Publication type:
- Article
Genetic context and aging influence anxiety‐like behavior in diverse mouse models of Alzheimer's disease: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044037
- By:
- Publication type:
- Article
Genetics, diet, and sex interact to modulate cognitive decline in Alzheimer's disease: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043779
- By:
- Publication type:
- Article
PLD3 is a neuronal lysosomal phospholipase D associated with β‐amyloid plaques and cognitive function in Alzheimer's disease: Molecular and cell biology/enzyme activities.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043301
- By:
- Publication type:
- Article
Sex differences in genetic predictors of resilience to Alzheimer's disease: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043259
- By:
- Publication type:
- Article
Discovering genetic variants contributing to sleep dysfunction in presymptomatic Alzheimer's mice: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042937
- By:
- Publication type:
- Article
Single nuclear RNA sequencing reveals microglia diversity associated with cognitive resilience in the AD‐BXD mouse model of human Alzheimer's disease: Molecular and cell biology: Inflammatory and microglia‐mediated mechanisms in AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041543
- By:
- Publication type:
- Article
P4‐088: GENE‐BY‐ENVIRONMENT REGULATION OF ALZHEIMER'S DISEASE PATHOGENESIS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1308, doi. 10.1016/j.jalz.2019.06.3748
- By:
- Publication type:
- Article
O4‐10‐05: MULTI‐OMIC ANALYSIS IDENTIFIES TRANSCRIPTIONAL NETWORKS AND DRIVERS ASSOCIATED WITH COGNITIVE AGING AND ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1260, doi. 10.1016/j.jalz.2019.06.4798
- By:
- Publication type:
- Article
P2‐130: BACKGROUND GENETICS IMPACTS MICROSTRUCTURE MEASURES IN MOTOR CORTEX AND HIPPOCAMPUS OF WILDTYPE AND 5XFAD MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P622, doi. 10.1016/j.jalz.2019.06.2537
- By:
- Publication type:
- Article
P2‐138: IDENTIFICATION OF SIPA1L1 AS A NOVEL CANDIDATE GENE MEDIATING PRECLINICAL WEIGHT LOSS IN A MOUSE MODEL OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P625, doi. 10.1016/j.jalz.2019.06.2545
- By:
- Publication type:
- Article
P4‐048: IDENTIFYING PRESYMPTOMATIC GENE SIGNATURES PREDICTIVE OF RESILIENCE TO ALZHEIMER'S.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1451, doi. 10.1016/j.jalz.2018.06.2450
- By:
- Publication type:
- Article
O4‐01‐06: WHOLE‐EXOME ANALYSIS OF LATE‐ONSET ALZHEIMER'S DISEASE REVEALS NOVEL CANDIDATE GENES INVOLVED IN COGNITIVE FUNCTION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1402, doi. 10.1016/j.jalz.2018.06.2914
- By:
- Publication type:
- Article
P3‐138: HYPOTHALAMIC ENERGY BALANCE DYSFUNCTION IN THE ETIOLOGY OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1121, doi. 10.1016/j.jalz.2018.06.1495
- By:
- Publication type:
- Article
P2‐110: CNS‐MEDIATED SENSORIMOTOR DECLINE IN A NOVEL TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P711, doi. 10.1016/j.jalz.2018.06.796
- By:
- Publication type:
- Article
P1‐147: GENE X DIET INTERACTIONS MODIFY SYMPTOMS OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P332, doi. 10.1016/j.jalz.2018.06.150
- By:
- Publication type:
- Article
Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice.
- Published in:
- PLoS ONE, 2024, v. 19, n. 3, p. 1, doi. 10.1371/journal.pone.0299595
- By:
- Publication type:
- Article
MAPPING RESILIENCE TO MOTOR SYMPTOMS AND FRAILTY IN ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P646, doi. 10.1016/j.jalz.2017.06.752
- By:
- Publication type:
- Article
DISCOVERING GENETIC MODIFIERS OF ALZHEIMER’S DISEASE USING NOVEL MOUSE MODELS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P975, doi. 10.1016/j.jalz.2017.06.1315
- By:
- Publication type:
- Article
Genetic background modifies CNS‐mediated sensorimotor decline in the AD‐BXD mouse model of genetic diversity in Alzheimer's disease.
- Published in:
- Genes, Brain & Behavior, 2019, v. 18, n. 8, p. N.PAG, doi. 10.1111/gbb.12603
- By:
- Publication type:
- Article
Diet composition, not calorie intake, rapidly alters intrinsic excitability of hypothalamic AgRP/NPY neurons in mice.
- Published in:
- Scientific Reports, 2015, p. 16810, doi. 10.1038/srep16810
- By:
- Publication type:
- Article
PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease.
- Published in:
- PLoS Genetics, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.pgen.1009406
- By:
- Publication type:
- Article
Tumor Necrosis Factor α Regulates Endothelial Progenitor Cell Migration via CADM1 and NF-kB.
- Published in:
- Stem Cells, 2016, v. 34, n. 7, p. 1922, doi. 10.1002/stem.2339
- By:
- Publication type:
- Article