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Target modulation and pharmacokinetics/pharmacodynamics translation of the BTK inhibitor poseltinib for model-informed phase II dose selection.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-98255-7
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- Article
HM71224, a selective Bruton's tyrosine kinase inhibitor, attenuates the development of murine lupus.
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- Arthritis Research & Therapy, 2017, v. 19, p. 1, doi. 10.1186/s13075-017-1402-1
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- Article
Synergistic Effects of BTK Inhibitor HM71224 and Methotrexate in a Collagen-induced Arthritis Rat Model.
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- In Vivo, 2021, v. 35, n. 6, p. 3245, doi. 10.21873/invivo.12619
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- Article
Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells.
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- Investigational New Drugs, 2020, v. 38, n. 6, p. 1696, doi. 10.1007/s10637-020-00956-9
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- Article
Safety pharmacology of sibutramine mesylate, an anti-obesity drug.
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- Human & Experimental Toxicology, 2005, v. 24, n. 3, p. 109, doi. 10.1191/0960327105ht510oa
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- Article
Comparative antihypertensive activities of losartan and HM70186 in rats with hepatic dysfunction.
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- Archives of Pharmacal Research, 2009, v. 32, n. 7, p. 1005, doi. 10.1007/s12272-009-1705-0
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- Article
HM71224, a novel Bruton's tyrosine kinase inhibitor, suppresses B cell and monocyte activation and ameliorates arthritis in a mouse model: a potential drug for rheumatoid arthritis.
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- Arthritis Research & Therapy, 2016, v. 18, p. 1, doi. 10.1186/s13075-016-0988-z
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- Article
Discovery of a Novel HDAC3 Selective Inhibitor and its Evaluation in Lymphoma Model.
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- Bulletin of the Korean Chemical Society, 2016, v. 37, n. 1, p. 42, doi. 10.1002/bkcs.10619
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- Article
Synthesis of Quinazoline Analogues with Differential Activity for HER2-overexpressing Breast Cancer Cells.
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- Bulletin of the Korean Chemical Society, 2015, v. 36, n. 7, p. 1933, doi. 10.1002/bkcs.10358
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- Article
Belvarafenib penetrates the BBB and shows potent antitumor activity in a murine melanoma brain metastasis model.
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- Clinical & Experimental Metastasis, 2023, v. 40, n. 2, p. 137, doi. 10.1007/s10585-023-10198-7
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- Article
Pharmacological evaluation of HM41322, a novel SGLT1/2 dual inhibitor, in vitro and in vivo.
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- Korean Journal of Physiology & Pharmacology, 2019, v. 23, n. 1, p. 55, doi. 10.4196/kjpp.2019.23.1.55
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- Article
Antitumor activity of HM781-36B, a highly effective pan-HER inhibitor in erlotinib-resistant NSCLC and other EGFR-dependent cancer models.
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- International Journal of Cancer, 2012, v. 130, n. 10, p. 2445, doi. 10.1002/ijc.26276
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- Article
Synthesis and antibacterial activity of new cephalosporins with lactonyloxyimino moiety.
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- Archives of Pharmacal Research, 1994, v. 17, n. 2, p. 87, doi. 10.1007/BF02974229
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- Article