Works by KALKHOVEN, Eric

Results: 51

Growth inhibition by anti-estrogens and progestins in TGF-β-resistant and -sensitive breast-tumor cells.

Published in:

International Journal of Cancer, 1996, v. 65, n. 5, p. 682, doi. 10.1002/(SICI)1097-0215(19960301)65:5<682::AID-IJC20>3.0.CO;2-8

By:

Kalkhoven, Eric;
Beraldi, Eliana;
Panno, M. Luisa;
De Winter, Johan P.;
Thijssen, Jos H. H.;
Van der Burg, Bart

Publication type:

Article

The role of TGF-β production in growth inhibition of breast-tumor cells by progestins.

Published in:

International Journal of Cancer, 1995, v. 61, n. 1, p. 80, doi. 10.1002/ijc.2910610114

By:

Kalkhoven, Eric;
Kwakkenbos-Isbrücker, Linda;
Mummery, Christine L.;
De Laat, Siegfried W.;
Van Den Eijnden-Van Raaij, Adriana J. M.;
Van Der Saag, Paul T.;
Burg, Bart Van Der

Publication type:

Article

PPARgamma in Metabolism, Immunity, and Cancer: Unified and Diverse Mechanisms of Action.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.624112

By:

Hernandez-Quiles, Miguel;
Broekema, Marjoleine F.;
Kalkhoven, Eric

Publication type:

Article

Familial Partial Lipodystrophy Phenotype Resulting from a Single-Base Mutation in Deoxyribonucleic Acid-Binding Domain of Peroxisome Proliferator-Activated Receptor-γ.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2007, v. 92, n. 5, p. 1606, doi. 10.1210/jc.2006-1807

By:

Monajemi, Houshang;
Lin Zhang;
Gang Li;
Jeninga, Ellen H.;
Henian Cao;
Maas, Mario;
Brouwer, C. B.;
Kalkhoven, Eric;
Stroes, Erik;
Hegele, Robert A.;
Leff, Todd

Publication type:

Article

Extracellular vesicle markers in relation to obesity and metabolic complications in patients with manifest cardiovascular disease.

Published in:

Cardiovascular Diabetology, 2014, v. 13, n. 1, p. 2, doi. 10.1186/1475-2840-13-37

By:

Kranendonk, Mariëtte E. G.;
De Kleijn, Dominique P. V.;
Kalkhoven, Eric;
Kanhai, Danny A.;
Uiterwaal, Cuno S. P. M.;
Van der Graaf, Yolanda;
Pasterkamp, Gerard;
Visseren, Frank L. J.

Publication type:

Article

Muscle-specific inflammation induced by MCP-1 overexpression does not affect whole-body insulin sensitivity in mice.

Published in:

Diabetologia, 2016, v. 59, n. 3, p. 624, doi. 10.1007/s00125-015-3822-2

By:

Evers-van Gogh, Inkie;
Oteng, Antwi-Boasiako;
Alex, Sheril;
Hamers, Nicole;
Catoire, Milene;
Stienstra, Rinke;
Kalkhoven, Eric;
Kersten, Sander

Publication type:

Article

Recurrent exon-deleting activating mutations in AHR act as drivers of urinary tract cancer.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-14256-0

By:

Vlaar, Judith M.;
Borgman, Anouska;
Kalkhoven, Eric;
Westland, Denise;
Besselink, Nicolle;
Shale, Charles;
Faltas, Bishoy M.;
Priestley, Peter;
Kuijk, Ewart;
Cuppen, Edwin

Publication type:

Article

A Single Complex Agpat2 Allele in a Patient With Partial Lipodystrophy.

Published in:

Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.01363

By:

Broekema, Marjoleine F.;
Massink, Maarten P. G.;
De Ligt, Joep;
Stigter, Edwin C. A.;
Monajemi, Houshang;
De Ridder, Jeroen;
Burgering, Boudewijn M. T.;
van Haaften, Gijs W.;
Kalkhoven, Eric

Publication type:

Article

Allele Compensation in Tip60+/− Mice Rescues White Adipose Tissue Function In Vivo.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0098343

By:

Gao, Yuan;
Hamers, Nicole;
Rakhshandehroo, Maryam;
Berger, Ruud;
Lough, John;
Kalkhoven, Eric

Publication type:

Article

PPARγ Regulates Expression of Carbohydrate Sulfotransferase 11 (CHST11/C4ST1), a Regulator of LPL Cell Surface Binding

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064284

By:

Tasdelen, Ismayil;
Berger, Ruud;
Kalkhoven, Eric

Publication type:

Article

Pmch-Deficiency in Rats Is Associated with Normal Adipocyte Differentiation and Lower Sympathetic Adipose Drive.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0060214

By:

Mul, Joram D.;
O’Duibhir, Eoghan;
Shrestha, Yogendra B.;
Koppen, Arjen;
Vargoviç, Peter;
Toonen, Pim W.;
Zarebidaki, Eleen;
Kvetnansky, Richard;
Kalkhoven, Eric;
Cuppen, Edwin;
Bartness, Timothy J.

Publication type:

Article

A Novel RNAi Lethality Rescue Screen to Identify Regulators of Adipogenesis.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. e37680, doi. 10.1371/journal.pone.0037680

By:

van Beekum, Olivier;
Yuan Gao;
Berger, Ruud;
Koppen, Arjen;
Kalkhoven, Eric

Publication type:

Article

Effect of Synthetic Dietary Triglycerides: A Novel Research Paradigm for Nutrigenomics.

Published in:

PLoS ONE, 2008, v. 3, n. 2, p. 1, doi. 10.1371/journal.pone.0001681

By:

Sanderson, Linda M.;
de Groot, Philip J.;
Hooiveld, Guido J. E. J.;
Koppen, Arjen;
Kalkhoven, Eric;
Müller, Michael;
Kersten, Sander

Publication type:

Article

Function of estrogen receptors in breast cancer.

Published in:

Breast Cancer (13406868), 1997, v. 4, n. 4, p. 204, doi. 10.1007/BF02966506

By:

Parker, Malcolm;
Cowley, Shaun;
Heery, David;
Henttu, Pirkko;
Kalkhoven, Eric;
Sjöberg, Maria;
Valentine, Janet;
White, Roger

Publication type:

Article

Immunometabolic Activation of Invariant Natural Killer T Cells.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01192

By:

Ververs, Francesca A.;
Kalkhoven, Eric;
van't Land, Belinda;
Boes, Marianne;
Schipper, Henk S.

Publication type:

Article

Natural killer T cells in adipose tissue prevent insulin resistance.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 9, p. 3343, doi. 10.1172/JCI62739

By:

Schipper, Henk S.;
Rakhshandehroo, Maryam;
van de Graaf, Stan F. J.;
Venken, Koen;
Koppen, Arjen;
Stienstra, Rinke;
Prop, Serge;
Meerding, Jenny;
Hamers, Nicole;
Besra, Gurdyal;
Boon, Louis;
Nieuwenhuis, Edward E. S.;
Elewaut, Dirk;
Prakken, Berent;
Kersten, Sander;
Boes, Marianne;
Kalkhoven, Eric

Publication type:

Article

Electric Pulse Stimulation of Myotubes as an In Vitro Exercise Model: Cell-Mediated and Non-Cell-Mediated Effects.

Published in:

Scientific Reports, 2015, p. 10944, doi. 10.1038/srep10944

By:

Evers-van Gogh, Inkie J.A.;
Alex, Sheril;
Stienstra, Rinke;
Brenkman, Arjan B.;
Kersten, Sander;
Kalkhoven, Eric

Publication type:

Article

P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma development.

Published in:

International Journal of Cancer, 2009, v. 124, n. 2, p. 339, doi. 10.1002/ijc.23977

By:

van Veelen, Wendy;
Klompmaker, Rob;
Gloerich, Martijn;
van Gasteren, Carola J.R.;
Kalkhoven, Eric;
Berger, Ruud;
Lips, Cornelis J.M.;
Medema, Rene H.;
Höppener, Jo W.M.;
Acton, Dennis S.

Publication type:

Article

Differential adipokine receptor expression on circulating leukocyte subsets in lean and obese children.

Published in:

PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0187068

By:

Keustermans, Genoveva;
van der Heijden, Laila B.;
Boer, Berlinda;
Scholman, Rianne;
Nuboer, Roos;
Pasterkamp, Gerard;
Prakken, Berent;
de Jager, Wilco;
Kalkhoven, Eric;
Janse, Arieke J.;
Schipper, Henk S.

Publication type:

Article

Short-Chain Fatty Acids Stimulate Angiopoietin-Like 4 Synthesis in Human Colon Adenocarcinoma Cells by Activating Peroxisome Proliferator-Activated Receptor γ.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 7, p. 1303, doi. 10.1128/MCB.00858-12

By:

Alex, Sheril;
Lange, Katja;
Amolo, Tom;
Grinstead, Jeffrey S.;
Haakonsson, Anders K.;
Szalowska, Ewa;
Koppen, Arjen;
Mudde, Karin;
Haenen, Daniëlle;
Al-Lahham, Sa'ad;
Roelofsen, Han;
Houtman, René;
van der Burg, Bart;
Mandrup, Susanne;
Bonvin, Alexandre M. J. J.;
Kalkhoven, Eric;
Müller, Michael;
Hooiveld, Guido J.;
Kersten, Sander

Publication type:

Article

Peroxisome Proliferator-Activated Receptor β/δ(PPARβ/δ) but Not PPARα Serves as a Plasma Free Fatty Acid Sensor in Liver.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 23, p. 9, doi. 10.1128/MCB.00370-09

By:

Sanderson, Linda M.;
Degenhardt, Tatjana;
Koppen, Arjen;
Kalkhoven, Eric;
Desvergne, Beatrice;
Müller, Michael;
Kersten, Sander

Publication type:

Article

The Multiple Endocrine Neoplasia Type 1 (MEN1) Tumor Suppressor Regulates Peroxisome Proliferator-Activated Receptor γ-Dependent Adipocyte Differentiation.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 18, p. 5060, doi. 10.1128/MCB.01001-08

By:

Dreijerink, Koen M. A.;
Varier, Radhika A.;
van Beekum, Olivier;
Jeninga, Ellen H.;
Höppener, Jo W. M.;
Lips, Cornelis J. M.;
Kummer, J. Alain;
Kalkhoven, Eric;
Marc Timmers, H. T.

Publication type:

Article

A signature motif in transcriptional co-activators mediates binding to nuclear receptors.

Published in:

Nature, 1997, v. 387, n. 6634, p. 733, doi. 10.1038/42750

By:

Heery, David M.;
Kalkhoven, Eric

Publication type:

Article

Loss of CBP acetyltransferase activity by PHD finger mutations in Rubinstein–Taybi syndrome.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 4, p. 441, doi. 10.1093/hmg/ddg039

By:

Kalkhoven, Eric;
Roelfsema, Jeroen H.;
Teunissen, Hans;
den Boer, Annemieke;
Ariyurek, Yavuz;
Zantema, Alt;
Breuning, Martijn H.;
Hennekam, Raoul C.M.;
Peters, Dorien J.M.

Publication type:

Article

Comprehensive Profiling of Mammalian Tribbles Interactomes Implicates TRIB3 in Gene Repression.

Published in:

Cancers, 2021, v. 13, n. 24, p. 6318, doi. 10.3390/cancers13246318

By:

Hernández-Quiles, Miguel;
Baak, Rosalie;
Borgman, Anouska;
den Haan, Suzanne;
Sobrevals Alcaraz, Paula;
van Es, Robert;
Kiss-Toth, Endre;
Vos, Harmjan;
Kalkhoven, Eric

Publication type:

Article

Targeting FOXO1 as an option to treat obesity?

Published in:

Cell Cycle, 2015, v. 14, n. 16, p. 2558, doi. 10.1080/15384101.2015.1060779

By:

Dansen, Tobias B;
Kalkhoven, Eric

Publication type:

Article

A specific lysine in c-Jun is required for transcriptional repression by E1A and is acetylated by p300.

Published in:

EMBO Journal, 2001, v. 20, n. 21, p. 6095, doi. 10.1093/emboj/20.21.6095

By:

Vries, Robert G. J.;
Prudenziati, Michela;
Zwartjes, Carin;
Verlaan, Matty;
Kalkhoven, Eric;
Zantema, Alt

Publication type:

Article

Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor.

Published in:

EMBO Journal, 1998, v. 17, n. 1, p. 232, doi. 10.1093/emboj/17.1.232

By:

Kalkhoven, Eric;
Valentine, Janet E.;
Heery, David M.;
Parker, Malcolm G.

Publication type:

Article

Ligand-independent activation of the oestrogen receptor by mutation of a conserved tyrosine.

Published in:

EMBO Journal, 1997, v. 16, n. 6, p. 1427, doi. 10.1093/emboj/16.6.1427

By:

White, Roger;
Sjöberg, Maria;
Kalkhoven, Eric;
Parker, Malcolm G.

Publication type:

Article

MOZ-TIF2 Inhibits Transcription by Nuclear Receptors and p53 by Impairment of CBP Function.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 3, p. 988, doi. 10.1128/MCB.25.3.988-1002.2005

By:

Kindle, Karin B.;
Troke, Philip J. F.;
Collins, Hilary M.;
Matsuda, Sachiko;
Bossi, Daniela;
Bellodi, Cristian;
Kalkhoven, Eric;
Salomoni, Paolo;
Pelicci, Pier Giuseppe;
Minucci, Saverio;
Heery, David M.

Publication type:

Article

Cascade of Distinct Histone Modifications during Collagenase Gene Activation.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 5, p. 1808, doi. 10.1128/MCB.23.5.1808-1816.2003

By:

Martens, Joost H.A.;
Verlaan, Matty;
Kalkhoven, Eric;
Zantema, Alt

Publication type:

Article

The relation between body iron stores and adipose tissue function in patients with manifest vascular disease.

Published in:

European Journal of Clinical Investigation, 2013, v. 43, n. 12, p. 1240, doi. 10.1111/eci.12165

By:

Westerink, Jan;
Olijhoek, Jobien K.;
Koppen, Arjen;
Faber, Daniël R.;
Kalkhoven, Eric;
Monajemi, Houshang;
Asbeck, B. Sweder;
Graaf, Yolanda;
Visseren, Frank L. J.

Publication type:

Article

Brown vs white adipocytes: The PPARγ coregulator story

Published in:

FEBS Letters, 2010, v. 584, n. 15, p. 3250, doi. 10.1016/j.febslet.2010.06.035

By:

Koppen, Arjen;
Kalkhoven, Eric

Publication type:

Article

A Multiplex Immunoassay for Human Adipokine Profiling.

Published in:

Clinical Chemistry, 2010, v. 56, n. 8, p. 1320, doi. 10.1373/clinchem.2010.146118

By:

Schipper, Henk S.;
de Jager, Wilco;
van Dijk, Mariska E. A.;
Meerding, Jenny;
Zelissen, Pierre M. J.;
Adan, Roger A.;
Prakken, Berent J.;
Kalkhoven, Eric

Publication type:

Article

Effect of extracellular vesicles of human adipose tissue on insulin signaling in liver and muscle cells.

Published in:

Obesity (19307381), 2014, v. 22, n. 10, p. 2216, doi. 10.1002/oby.20847

By:

Kranendonk, Mariëtte E.G.;
Visseren, Frank L.J.;
Herwaarden, Joost A.;
Nolte‐'t Hoen, Esther N.M.;
Jager, Wilco;
Wauben, Marca H.M.;
Kalkhoven, Eric

Publication type:

Article

Human adipocyte extracellular vesicles in reciprocal signaling between adipocytes and macrophages.

Published in:

Obesity (19307381), 2014, v. 22, n. 5, p. 1296, doi. 10.1002/oby.20679

By:

Kranendonk, Mariëtte E.G.;
Visseren, Frank L.J.;
Balkom, Bas W.M.;
Nolte ‐ 't Hoen, Esther N.M.;
Herwaarden, Joost A.;
Jager, Wilco;
Schipper, Henk S.;
Brenkman, Arjan B.;
Verhaar, Marianne C.;
Wauben, Marca H.M.;
Kalkhoven, Eric

Publication type:

Article

Posttranslational Modifications of PPAR-γ: Fine-tuning the Metabolic Master Regulator.

Published in:

Obesity (19307381), 2009, v. 17, n. 2, p. 213, doi. 10.1038/oby.2008.473

By:

Van Beekum, Olivier;
Fleskens, Veerle;
Kalkhoven, Eric

Publication type:

Article

Lipid accumulation in adipose tissue-resident iNKT cells contributes to an inflammatory phenotype.

Published in:

Adipocyte, 2024, v. 13, n. 1, p. 1, doi. 10.1080/21623945.2024.2421750

By:

Morris, Imogen;
Vrieling, Frank;
Bouwman, Annemieke;
Stienstra, Rinke;
Kalkhoven, Eric

Publication type:

Article

TIPping the balance in adipogenesis.

Published in:

Adipocyte, 2014, v. 3, n. 2, p. 160, doi. 10.4161/adip.28307

By:

Gao, Yuan;
Kalkhoven, Eric

Publication type:

Article

Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.

Published in:

Nature Communications, 2013, v. 4, n. 10, p. 2656, doi. 10.1038/ncomms3656

By:

Gao, Yuan;
Koppen, Arjen;
Rakhshandehroo, Maryam;
Tasdelen, Ismayil;
van de Graaf, Stan F.;
van Loosdregt, Jorg;
van Beekum, Olivier;
Hamers, Nicole;
van Leenen, Dik;
Berkers, Celia R.;
Berger, Ruud;
Holstege, Frank C.P.;
Coffer, Paul J.;
Brenkman, Arjan B.;
Ovaa, Huib;
Kalkhoven, Eric

Publication type:

Article

Endogenous lipid antigens for invariant natural killer T cells hold the reins in adipose tissue homeostasis.

Published in:

Immunology, 2018, v. 153, n. 2, p. 179, doi. 10.1111/imm.12839

By:

van Eijkeren, Robert J.;
Krabbe, Olga;
Boes, Marianne;
Schipper, Henk S.;
Kalkhoven, Eric

Publication type:

Article

TRIB3 Modulates PPARγ-Mediated Growth Inhibition by Interfering with the MLL Complex in Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 18, p. N.PAG, doi. 10.3390/ijms231810535

By:

Hernández-Quiles, Miguel;
Baak, Rosalie;
Orea-Soufi, Alba;
Borgman, Anouska;
den Haan, Suzanne;
Sobrevals Alcaraz, Paula;
Jongejan, Aldo;
van Es, Robert;
Velasco, Guillermo;
Vos, Harmjan;
Kalkhoven, Eric

Publication type:

Article

Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery.

Published in:

Analytical & Bioanalytical Chemistry, 2012, v. 404, n. 5, p. 1413, doi. 10.1007/s00216-012-6226-x

By:

Strassburg, Katrin;
Huijbrechts, Annemarie;
Kortekaas, Kirsten;
Lindeman, Jan;
Pedersen, Theresa;
Dane, Adrie;
Berger, Ruud;
Brenkman, Arjan;
Hankemeier, Thomas;
Duynhoven, John;
Kalkhoven, Eric;
Newman, John;
Vreeken, Rob

Publication type:

Article

The serine/threonine phosphatase PPM1B (PP2Cß) selectively modulates PPARγ activity.

Published in:

Biochemical Journal, 2013, v. 451, n. 1, p. 45, doi. 10.1042/BJ20121113

By:

TASDELEN, Ismayil;
VAN BEEKUM, Olivier;
GORBENKO, Olena;
FLESKENS, Veerle;
VAN DEN BROEK, Niels J. F.;
KOPPEN, Arjen;
HAMERS, Nicole;
BERGER, Ruud;
COFFER, Paul J.;
BRENKMAN, Arjan B.;
KALKHOVEN, Eric

Publication type:

Article

Pref-1 preferentially inhibits heat production in brown adipose tissue.

Published in:

Biochemical Journal, 2012, v. 443, n. 3, p. e3, doi. 10.1042/BJ20120382

By:

RAKHSHANDEHROO, Maryam;
KOPPEN, Arjen;
KALKHOVEN, Eric

Publication type:

Article

Cytokine Output of Adipocyte-iNKT Cell Interplay Is Skewed by a Lipid-Rich Microenvironment.

Published in:

Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.00479

By:

van Eijkeren, Robert J.;
Morris, Imogen;
Borgman, Anouska;
Markovska, Angela;
Kalkhoven, Eric

Publication type:

Article

An Oral Mixed Fat Load Is Followed by a Modest Anti-inflammatory Adipocytokine Response in Overweight Patients with Metabolic Syndrome.

Published in:

Lipids, 2014, v. 49, n. 3, p. 247, doi. 10.1007/s11745-014-3877-8

By:

Westerink, Jan;
Hajer, Gideon R.;
Kranendonk, Mariëtte E. G.;
Schipper, Henk S.;
Monajemi, Houshang;
Kalkhoven, Eric;
Visseren, Frank L. J.

Publication type:

Article

Expression of the Glucocorticoid Receptor mRNA Is Regulated during Early Xenopus laevis Embryonic Development.

Published in:

Annals of the New York Academy of Sciences, 1993, v. 684, n. 1, p. 205, doi. 10.1111/j.1749-6632.1993.tb32285.x

By:

GAO, XIANGMING;
KALKHOVEN, ERIC;
PETERSON-MADURO, JOSELIN;
DESTRÉE, OLIVIER H. J.

Publication type:

Article

Synthetic Progestins in Breast Tumor Cells.

Published in:

Annals of the New York Academy of Sciences, 1993, v. 684, n. 1, p. 220, doi. 10.1111/j.1749-6632.1993.tb32290.x

By:

KALKHOVEN, ERIC;
KWAKKENBOS-ISBRÜCKER, LINDA;
LAAT, SIEGFRIED W.;
BURG, BART

Publication type:

Article

Nuclear receptor Nur77 and Yin‐Yang 1 synergistically increase mitochondrial abundance and activity in macrophages.

Published in:

FEBS Letters, 2024, v. 598, n. 14, p. 1715, doi. 10.1002/1873-3468.14942

By:

Koenis, Duco S.;
Evers‐van Gogh, Inkie J. A.;
van Loenen, Pieter B.;
Zwart, Wilbert;
Kalkhoven, Eric;
de Vries, Carlie J. M.

Publication type:

Article