Works by Küppers, Jim

Results: 13

Tetrahydroimidazo[1,2‐a]pyrazine Derivatives: Synthesis and Evaluation as Gαq‐Protein Ligands.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 55, p. 12615, doi. 10.1002/chem.202001446

By:

Küppers, Jim;
Benkel, Tobias;
Annala, Suvi;
Kimura, Kenichi;
Reinelt, Lisa;
Fleischmann, Bernd K.;
Kostenis, Evi;
Gütschow, Michael

Publication type:

Article

Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

Published in:

2020

By:

Kuschak, Markus;
Namasivayam, Vigneshwaran;
Rafehi, Muhammad;
Voss, Jan H.;
Garg, Jaspal;
Schlegel, Jonathan G.;
Abdelrahman, Aliaa;
Kehraus, Stefan;
Reher, Raphael;
Küppers, Jim;
Sylvester, Katharina;
Hinz, Sonja;
Matthey, Michaela;
Wenzel, Daniela;
Fleischmann, Bernd K.;
Pfeifer, Alexander;
Inoue, Asuka;
Gütschow, Michael;
König, Gabriele M.;
Müller, Christa E.

Publication type:

journal article

Crosstalk between angiotensin and the nonamyloidogenic pathway of Alzheimer's amyloid precursor protein.

Published in:

FEBS Journal, 2017, v. 284, n. 5, p. 742, doi. 10.1111/febs.14015

By:

Kanarek, Anna Maria;
Wagner, Annika;
Küppers, Jim;
Gütschow, Michael;
Postina, Rolf;
Kojro, Elzbieta

Publication type:

Article

Case report: Detecting giant cell arteritis in [68Ga]Ga-DOTA-Siglec-9-PET/CT.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1501790

By:

Petzinna, Simon M.;
Küppers, Jim;
Schemmer, Benedikt;
Kernder, Anna L.;
Bauer, Claus-Jürgen;
von der Emde, Leon;
Salam, Babak;
Distler, Jörg H. W.;
Winklbauer, Anja;
Essler, Markus;
Schäfer, Valentin S.

Publication type:

Article

Case report: Detecting giant cell arteritis in [68Ga]Ga-DOTA-Siglec-9-PET/CT.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1501790

By:

Petzinna, Simon M.;
Küppers, Jim;
Schemmer, Benedikt;
Kernder, Anna L.;
Bauer, Claus-Jürgen;
von der Emde, Leon;
Salam, Babak;
Distler, Jörg H. W.;
Winklbauer, Anja;
Essler, Markus;
Schäfer, Valentin S.

Publication type:

Article

Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20418-3

By:

Hermes, Cornelia;
Richarz, René;
Wirtz, Daniel A.;
Patt, Julian;
Hanke, Wiebke;
Kehraus, Stefan;
Voß, Jan Hendrik;
Küppers, Jim;
Ohbayashi, Tsubasa;
Namasivayam, Vigneshwaran;
Alenfelder, Judith;
Inoue, Asuka;
Mergaert, Peter;
Gütschow, Michael;
Müller, Christa E.;
Kostenis, Evi;
König, Gabriele M.;
Crüsemann, Max

Publication type:

Article

Aminoalkoxy‐substituted coumarins: Synthesis and evaluation for reactivation of inhibited human acetylcholinesterase.

Published in:

Archiv der Pharmazie, 2022, v. 355, n. 11, p. 1, doi. 10.1002/ardp.202200208

By:

Elsinghorst, Paul W.;
Wille, Timo;
Barić, Danijela;
Mertens, Matthias D.;
Baumann, Madlen;
Küppers, Jim;
Gütschow, Michael

Publication type:

Article

Bioanalytical verification of V-type nerve agent exposure: simultaneous detection of phosphonylated tyrosines and cysteine-containing disulfide-adducts derived from human albumin.

Published in:

Analytical & Bioanalytical Chemistry, 2018, v. 410, n. 5, p. 1463, doi. 10.1007/s00216-017-0787-7

By:

Kranawetvogl, Andreas;
Küppers, Jim;
Siegert, Markus;
Gütschow, Michael;
Worek, Franz;
Thiermann, Horst;
Elsinghorst, Paul W.;
John, Harald

Publication type:

Article

Study Protocol of a Prospective, Monocentric, Single-Arm Study Investigating the Safety and Efficacy of Local Ablation of Symptomatic Uterine Fibroids with US-Guided High-Intensity Focused Ultrasound (HIFU).

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 18, p. 5926, doi. 10.3390/jcm12185926

By:

Matlac, Dieter M.;
Tonguc, Tolga;
Mutschler, Nikola;
Recker, Florian;
Ramig, Olga;
Strunk, Holger M.;
Dell, Tatjana;
Pieper, Claus C.;
Coenen, Martin;
Fuhrmann, Christine;
Vautey, Oregan;
Egger, Eva-Katharina;
Küppers, Jim;
Conrad, Rupert;
Essler, Markus;
Mustea, Alexander;
Marinova, Milka

Publication type:

Article

Convergent Synthesis of Two Fluorescent Ebselen-Coumarin Heterodimers.

Published in:

Pharmaceuticals (14248247), 2016, v. 9, n. 3, p. 43, doi. 10.3390/ph9030043

By:

Küppers, Jim;
Schulz-Fincke, Anna Christina;
Palus, Jerzy;
Giurg, Mirosław;
Skar˙zewski, Jacek;
Gütschow, Michael

Publication type:

Article

Radiolabeling Strategies of Nanobodies for Imaging Applications.

Published in:

Diagnostics (2075-4418), 2021, v. 11, n. 9, p. 1530, doi. 10.3390/diagnostics11091530

By:

Küppers, Jim;
Kürpig, Stefan;
Bundschuh, Ralph A.;
Essler, Markus;
Lütje, Susanne

Publication type:

Article

Identification of novel disulfide adducts between the thiol containing leaving group of the nerve agent VX and cysteine containing tripeptides derived from human serum albumin.

Published in:

Drug Testing & Analysis, 2017, v. 9, n. 8, p. 1192, doi. 10.1002/dta.2144

By:

Kranawetvogl, Andreas;
Küppers, Jim;
Gütschow, Michael;
Worek, Franz;
Thiermann, Horst;
Elsinghorst, Paul W.;
John, Harald

Publication type:

Article

Ablation of symptomatic uterine fibroids with the Mirabilis system for rapid noninvasive ultrasound-guided high-intensity focused ultrasound (HIFU): a prospective observational clinical study.

Published in:

La Radiologia Medica, 2025, v. 130, n. 5, p. 629, doi. 10.1007/s11547-025-01972-6

By:

Tonguc, Tolga;
Savchenko, Oleksandr;
Ramig, Olga;
Stader, Judith M.;
Kießling, Franziska;
Küppers, Jim;
Egger, Eva K.;
Thudium, Marcus;
Martin, Patrick;
Poll, Wayne;
Schild, Hans H.;
Conrad, Rupert;
Essler, Markus;
Mustea, Alexander;
Strunk, Holger M.;
Marinova, Milka

Publication type:

Article

Works by Küppers, Jim

Tetrahydroimidazo[1,2‐a]pyrazine Derivatives: Synthesis and Evaluation as Gα<sub>q</sub>‐Protein Ligands.

Cell-permeable high-affinity tracers for G<sub>q</sub> proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

Crosstalk between angiotensin and the nonamyloidogenic pathway of Alzheimer's amyloid precursor protein.

Case report: Detecting giant cell arteritis in [<sup>68</sup>Ga]Ga-DOTA-Siglec-9-PET/CT.

Case report: Detecting giant cell arteritis in [<sup>68</sup>Ga]Ga-DOTA-Siglec-9-PET/CT.

Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359.

Aminoalkoxy‐substituted coumarins: Synthesis and evaluation for reactivation of inhibited human acetylcholinesterase.

Bioanalytical verification of V-type nerve agent exposure: simultaneous detection of phosphonylated tyrosines and cysteine-containing disulfide-adducts derived from human albumin.

Study Protocol of a Prospective, Monocentric, Single-Arm Study Investigating the Safety and Efficacy of Local Ablation of Symptomatic Uterine Fibroids with US-Guided High-Intensity Focused Ultrasound (HIFU).

Convergent Synthesis of Two Fluorescent Ebselen-Coumarin Heterodimers.

Radiolabeling Strategies of Nanobodies for Imaging Applications.

Identification of novel disulfide adducts between the thiol containing leaving group of the nerve agent VX and cysteine containing tripeptides derived from human serum albumin.

Ablation of symptomatic uterine fibroids with the Mirabilis system for rapid noninvasive ultrasound-guided high-intensity focused ultrasound (HIFU): a prospective observational clinical study.