Works matching AU Juvonen, Risto O.

Results: 15

Anthraquinone biocolourant dermocybin is metabolized whereas dermorubin is not in in vitro liver fractions and recombinant metabolic enzymes.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 6, p. 846, doi. 10.1111/bcpt.14013

By:

Yli‐Öyrä, Johanna;
Juvonen, Risto O.;
Lehtonen, Marko;
Herrala, Mikko;
Finel, Moshe;
Räisänen, Riikka;
Rysä, Jaana

Publication type:

Article

Molecular docking and oxidation kinetics of 3-phenyl coumarin derivatives by human CYP2A13.

Published in:

Xenobiotica, 2021, v. 51, n. 11, p. 1207, doi. 10.1080/00498254.2021.1898700

By:

Juvonen, Risto O.;
Jokinen, Elmeri M.;
Huuskonen, Juhani;
Kärkkäinen, Olli;
Raunio, Hannu;
Pentikäinen, Olli T.

Publication type:

Article

Tissue and interspecies comparison of catechol-O-methyltransferase mediated catalysis of 6-O-methylation of esculetin to scopoletin and its inhibition by entacapone and tolcapone.

Published in:

Xenobiotica, 2021, v. 51, n. 3, p. 268, doi. 10.1080/00498254.2020.1853850

By:

Jalkanen, Aaro;
Lassheikki, Veera;
Torsti, Tommi;
Gharib, Elham;
Lehtonen, Marko;
Juvonen, Risto O.

Publication type:

Article

In vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species.

Published in:

Xenobiotica, 2020, v. 50, n. 8, p. 885, doi. 10.1080/00498254.2020.1711544

By:

Juvonen, Risto O.;
Pentikäinen, Olli;
Huuskonen, Juhani;
Timonen, Juri;
Kärkkäinen, Olli;
Heikkinen, Aki;
Fashe, Muluneh;
Raunio, Hannu

Publication type:

Article

Development of new Coumarin-based profluorescent substrates for human cytochrome P450 enzymes.

Published in:

Xenobiotica, 2019, v. 49, n. 9, p. 1015, doi. 10.1080/00498254.2018.1530399

By:

Juvonen, Risto O.;
Raunio, Hannu;
Ahinko, Mira;
Pentikäinen, Olli T.;
Huuskonen, Juhani

Publication type:

Article

Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes.

Published in:

Frontiers in Pharmacology, 2015, p. 1, doi. 10.3389/fphar.2015.00123

By:

Raunio, Hannu;
Kuusisto, Mira;
Juvonen, Risto O.;
Pentikäinen, Olli T.;
Fourches, Denis;
Mumtaz, Moiz M.

Publication type:

Article

In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity.

Published in:

Archives of Toxicology, 2022, v. 96, n. 3, p. 793, doi. 10.1007/s00204-021-03218-6

By:

Šadibolová, Michaela;
Juvonen, Risto O.;
Auriola, Seppo;
Boušová, Iva

Publication type:

Article

Blocking oestradiol synthesis pathways with potent and selective coumarin derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 743, doi. 10.1080/14756366.2018.1452919

By:

Niinivehmas, Sanna;
Postila, Pekka A.;
Rauhamäki, Sanna;
Manivannan, Elangovan;
Kortet, Sami;
Ahinko, Mira;
Huuskonen, Pasi;
Nyberg, Niina;
Koskimies, Pasi;
Lätti, Sakari;
Multamäki, Elina;
Juvonen, Risto O.;
Raunio, Hannu;
Pasanen, Markku;
Huuskonen, Juhani;
Pentikäinen, Olli T.

Publication type:

Article

Toxicological Information Literacy Protects Human Health.

Published in:

Science & Technology Libraries, 2022, v. 41, n. 4, p. 422, doi. 10.1080/0194262X.2021.2023378

By:

Juvonen, Risto O.;
Laitinen, Heikki;
Saarti, Jarmo

Publication type:

Article

Western Diet Decreases Hepatic Drug Metabolism in Male LDLr<sup>−/−</sup>ApoB<sup>100/100</sup> Mice.

Published in:

Journal of Nutrition & Metabolism, 2023, p. 1, doi. 10.1155/2023/5599789

By:

Koponen, Markus;
Rysä, Jaana;
Ruotsalainen, Anna-Kaisa;
Kärkkäinen, Olli;
Juvonen, Risto O.

Publication type:

Article

Inhibitory effects and oxidation of 6-methylcoumarin, 7-methylcoumarin and 7-formylcoumarin via human CYP2A6 and its mouse and pig orthologous enzymes.

Published in:

Xenobiotica, 2016, v. 46, n. 1, p. 14, doi. 10.3109/00498254.2015.1048327

By:

Juvonen, Risto O.;
Kuusisto, Mira;
Fohrgrup, Carolin;
Pitkänen, Mari H.;
Nevalainen, Tapio J.;
Auriola, Seppo;
Raunio, Hannu;
Pasanen, Markku;
Pentikäinen, Olli T.

Publication type:

Article

A high throughput assay for the glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin by recombinant human UDP-glucuronosyltransferases and liver microsomes.

Published in:

Xenobiotica, 2013, v. 43, n. 10, p. 853, doi. 10.3109/00498254.2013.783724

By:

Rahikainen, Tuomas;
Häkkinen, Merja R.;
Finel, Moshe;
Pasanen, Markku;
Juvonen, Risto O.

Publication type:

Article

New glutathione conjugate of pyrrolizidine alkaloids produced by human cytosolic enzyme‐dependent reactions in vitro.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2018, v. 32, n. 16, p. 1344, doi. 10.1002/rcm.8173

By:

Muluneh, Fashe;
Häkkinen, Merja R.;
El‐Dairi, Rami;
Pasanen, Markku;
Juvonen, Risto O.

Publication type:

Article

Coumarin-Based Profluorescent and Fluorescent Substrates for Determining Xenobiotic-Metabolizing Enzyme Activities In Vitro.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 13, p. 4708, doi. 10.3390/ijms21134708

By:

Raunio, Hannu;
Pentikäinen, Olli;
Juvonen, Risto O.

Publication type:

Article

Lack of increased oxidative stress in catechol-O-methyltransferase (COMT)-deficient mice.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 370, n. 4, p. 279, doi. 10.1007/s00210-004-0967-9

By:

Forsberg, Markus M.;
Juvonen, Risto O.;
Helisalmi, Petra;
Leppänen, Jukka;
Gogos, Joseph A.;
Karayiorgou, Maria;
Männistö, Pekka T.

Publication type:

Article