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Extending human healthspan and longevity: a symposium report.
Published in:
Annals of the New York Academy of Sciences, 2022, v. 1507, n. 1, p. 70, doi. 10.1111/nyas.14681
By:
- DeVito, Loren M.;
- Barzilai, Nir;
- Cuervo, Ana Maria;
- Niedernhofer, Laura J.;
- Milman, Sofiya;
- Levine, Morgan;
- Promislow, Daniel;
- Ferrucci, Luigi;
- Kuchel, George A.;
- Mannick, Joan;
- Justice, Jamie;
- Gonzales, Mitzi M.;
- Kirkland, James L.;
- Cohen, Pinchas;
- Campisi, Judith
Publication type:
Article
Bringing Geroscience into the Mainstream: From Education to Clinical Practice, What Will It Take?
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2024, v. 79, n. 9, p. 1, doi. 10.1093/gerona/glae020
By:
- Al-Naggar, Iman M;
- Campellone, Kenneth G;
- Espinoza, Sara E;
- Justice, Jamie N;
- Orr, Miranda E;
- Kozikowski, Chester;
- van der Willik, Odette;
- Thatcher, Christine;
- Schmader, Kenneth;
- Pignolo, Robert J;
- Newman, John C;
- Kuchel, George A
Publication type:
Article
Association of a Blood-Based Aging Biomarker Index With Death and Chronic Disease: Cardiovascular Health Study.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2024, v. 79, n. 2, p. 1, doi. 10.1093/gerona/glad172
By:
- Zhang, Xiao;
- Sanders, Jason L;
- Boudreau, Robert M;
- Arnold, Alice M;
- Justice, Jamie N;
- Espeland, Mark A;
- Kuchel, George A;
- Barzilai, Nir;
- Kuller, Lewis H;
- Lopez, Oscar L;
- Kritchevsky, Stephen B;
- Newman, Anne B
Publication type:
Article
Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2024, v. 79, n. 1, p. 1, doi. 10.1093/gerona/glad214
By:
- Justice, Jamie N;
- Leng, Xiaoyan I;
- LeBrasseur, Nathan K;
- Tchkonia, Tamara;
- Kirkland, James L;
- Mitin, Natalia;
- Liu, Yongmei;
- Kritchevsky, Stephen B;
- Nicklas, Barbara J;
- Ding, Jingzhong
Publication type:
Article
Eight-Year Changes in Multimorbidity and Frailty in Adults With Type 2 Diabetes Mellitus: Associations With Cognitive and Physical Function and Mortality.
Published in:
2022
By:
- Espeland, Mark A;
- Justice, Jamie Nicole;
- Bahnson, Judy;
- Evans, Joni K;
- Munshi, Medha;
- Hayden, Kathleen M;
- Simpson, Felicia R;
- Johnson, Karen C;
- Johnston, Craig;
- Kritchevsky, Stephen R;
- Look AHEAD Research Group
Publication type:
journal article
Metformin Reduces Aging-Related Leaky Gut and Improves Cognitive Function by Beneficially Modulating Gut Microbiome/Goblet Cell/Mucin Axis.
Published in:
2020
By:
- Ahmadi, Shokouh;
- Razazan, Atefeh;
- Nagpal, Ravinder;
- Jain, Shalini;
- Wang, Bo;
- Mishra, Sidharth P;
- Wang, Shaohua;
- Justice, Jamie;
- Ding, Jingzhong;
- McClain, Donald A;
- Kritchevsky, Stephen B;
- Kitzman, Dalane;
- Yadav, Hariom
Publication type:
journal article
Testing the Geroscience Hypothesis: Early Days.
Published in:
2020
By:
- Kritchevsky, Stephen B;
- Justice, Jamie N
Publication type:
Editorial
Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women.
Published in:
2018
By:
- Justice, Jamie N.;
- Gregory, Heather;
- Tchkonia, Tamar;
- LeBrasseur, Nathan K.;
- Kirkland, James L.;
- Kritchevsky, Stephen B.;
- Nicklas, Barbara J.
Publication type:
journal article
Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes.
Published in:
2016
By:
- Justice, Jamie;
- Miller, Jordan D.;
- Newman, John C.;
- Hashmi, Shahrukh K.;
- Halter, Jeffrey;
- Austad, Steve N.;
- Barzilai, Nir;
- Kirkland, James L.
Publication type:
journal article
Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience.
Published in:
2016
By:
- Huffman, Derek M.;
- Justice, Jamie N.;
- Stout, Michael B.;
- Kirkland, James L.;
- Barzilai, Nir;
- Austad, Steven N.
Publication type:
journal article
Comparative Approaches to Understanding the Relation Between Aging and Physical Function.
Published in:
2016
By:
- Justice, Jamie N.;
- Cesari, Matteo;
- Seals, Douglas R.;
- Shively, Carol A.;
- Carter, Christy S.
Publication type:
journal article
Men show increased brain aging with respect to women among Cognitively Normal Individuals.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073750
By:
- Casanova, Ramon;
- Lu, Lingyi;
- Hsu, Fang‐Chi;
- Anderson, Andrea;
- Barnard, Ryan;
- Justice, Jamie;
- Bateman, James R.;
- Lockhart, Samuel N.;
- Walker, Keenan A.;
- Hughes, Tim M.;
- Kritchevsky, Stephen B;
- Espeland, Mark A.;
- Craft, Suzanne
Publication type:
Article
MRI‐based measure of dementia risk derived using machine learning is strongly associated with measures of longevity and biological age.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.061899
By:
- Casanova, Ramon;
- Anderson, Andrea;
- Barnard, Ryan;
- Justice, Jamie;
- Kucharska‐Newton, Anna;
- Windham, B Gwen;
- Palta, Priya;
- Gottesman, Rebecca F.;
- Mosley, Thomas H.;
- Hughes, Tim M.;
- Wagenknecht, Lynne E;
- Kritchevsky, Stephen B
Publication type:
Article
Changes in clinical indices of multimorbidity and frailty predict subsequent cognitive decline: Findings from the Look AHEAD and Look AHEAD MIND studies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054943
By:
- Espeland, Mark A.;
- Bahnson, Judy;
- Evans, Joni K.;
- Hayden, Kathleen M.;
- Justice, Jamie;
- Johnson, Karen C.;
- Johnston, Craig;
- Munshi, Medha;
- Simpson, Felicia R.;
- Kritchevsky, Stephen B.
Publication type:
Article
Predicting cognitive resiliency in older women using machine learning: Epidemiology / Risk and protective factors in MCI and dementia.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041137
By:
- Casanova, Ramon;
- Gaussoin, Sarah A;
- Wallace, Robert B;
- Baker, Laura D;
- Sachs, Bonnie C;
- Justice, Jamie;
- Chen, Jiu‐Chiuan;
- Manson, JoAnn E;
- Henderson, Victor;
- Whitsel, Eric A;
- Hayden, Kathleen M;
- Rapp, Stephen R
Publication type:
Article
Analysis of Epigenetic Age Acceleration and Healthy Longevity Among Older US Women.
Published in:
JAMA Network Open, 2022, v. 5, n. 7, p. e2223285, doi. 10.1001/jamanetworkopen.2022.23285
By:
- Jain, Purva;
- Binder, Alexandra M.;
- Chen, Brian;
- Parada Jr, Humberto;
- Gallo, Linda C.;
- Alcaraz, John;
- Horvath, Steve;
- Bhatti, Parveen;
- Whitsel, Eric A.;
- Jordahl, Kristina;
- Baccarelli, Andrea A.;
- Hou, Lifang;
- Stewart, James D.;
- Li, Yun;
- Justice, Jamie N.;
- LaCroix, Andrea Z.
Publication type:
Article
Associations of plasma proteomics and age-related outcomes with brain age in a diverse cohort.
Published in:
GeroScience, 2024, v. 46, n. 4, p. 3861, doi. 10.1007/s11357-024-01112-4
By:
- Casanova, Ramon;
- Walker, Keenan A.;
- Justice, Jamie N.;
- Anderson, Andrea;
- Duggan, Michael R.;
- Cordon, Jenifer;
- Barnard, Ryan T.;
- Lu, Lingyi;
- Hsu, Fang-Chi;
- Sedaghat, Sanaz;
- Prizment, Anna;
- Kritchevsky, Stephen B.;
- Wagenknecht, Lynne E.;
- Hughes, Timothy M.
Publication type:
Article
Percutaneous biopsies of skeletal muscle and adipose tissue in individuals older than 70: methods and outcomes in the Study of Muscle, Mobility and Aging (SOMMA).
Published in:
GeroScience, 2024, v. 46, n. 3, p. 3419, doi. 10.1007/s11357-024-01087-2
By:
- Zamora, Zeke;
- Lui, Li-Yung;
- Sparks, Lauren M.;
- Justice, Jamie;
- Lyles, Mary;
- Gentle, Landon;
- Gregory, Heather;
- Yeo, Reichelle X.;
- Kershaw, Erin E.;
- Stefanovic-Racic, Maja;
- Newman, Anne B.;
- Kritchevsky, Stephen;
- Toledo, Frederico G. S.
Publication type:
Article
Resilience, aging, and response to radiation exposure (RARRE) in nonhuman primates: a resource review.
Published in:
GeroScience, 2023, v. 45, n. 6, p. 3371, doi. 10.1007/s11357-023-00812-7
By:
- Schaaf, George W.;
- Justice, Jamie N.;
- Quillen, Ellen E.;
- Cline, J. Mark
Publication type:
Article
Long-term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design.
Published in:
GeroScience, 2023, v. 45, n. 5, p. 2785, doi. 10.1007/s11357-023-00830-5
By:
- Ruggiero, Alistaire D.;
- Vemuri, Ravichandra;
- Blawas, Megan;
- Long, Masha;
- DeStephanis, Darla;
- Williams, Abigail G.;
- Chen, Haiying;
- Justice, Jamie N.;
- Macauley, Shannon L.;
- Day, Steven M.;
- Kavanagh, Kylie
Publication type:
Article
Is an MRI-derived anatomical measure of dementia risk also a measure of brain aging?
Published in:
GeroScience, 2023, v. 45, n. 1, p. 439, doi. 10.1007/s11357-022-00650-z
By:
- Casanova, Ramon;
- Anderson, Andrea M.;
- Barnard, Ryan T.;
- Justice, Jamie N.;
- Kucharska-Newton, Anna;
- Windham, Beverly Gwen;
- Palta, Priya;
- Gottesman, Rebecca F.;
- Mosley, Thomas H.;
- Hughes, Timothy M.;
- Wagenknecht, Lynne E.;
- Kritchevsky, Stephen B.
Publication type:
Article
Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop.
Published in:
GeroScience, 2022, v. 44, n. 6, p. 2573, doi. 10.1007/s11357-022-00661-w
By:
- Brinkley, Tina E.;
- Justice, Jamie N.;
- Basu, Shubhashrita;
- Bauer, Scott R.;
- Loh, Kah Poh;
- Mukli, Peter;
- Ng, Ted Kheng Siang;
- Turney, Indira C.;
- Ferrucci, Luigi;
- Cummings, Steven R.;
- Kritchevsky, Stephen B.
Publication type:
Article
Evaluation of a blood-based geroscience biomarker index in a randomized trial of caloric restriction and exercise in older adults with heart failure with preserved ejection fraction.
Published in:
GeroScience, 2022, v. 44, n. 2, p. 983, doi. 10.1007/s11357-021-00509-9
By:
- Justice, Jamie N.;
- Pajewski, Nicholas M.;
- Espeland, Mark A.;
- Brubaker, Peter;
- Houston, Denise K.;
- Marcovina, Santica;
- Nicklas, Barbara J.;
- Kritchevsky, Stephen B.;
- Kitzman, Dalane W.
Publication type:
Article
Correction to: Temporal emergence of age-associated changes in cognitive and physical function in vervets (Chlorocebus aethiops sabaeus).
Published in:
2021
By:
- Frye, Brett M.;
- Valure, Payton M.;
- Craft, Suzanne;
- Baxter, Mark G.;
- Scott, Christie;
- Wise-Walden, Shanna;
- Bissinger, David W.;
- Register, Hannah M.;
- Copeland, Carson;
- Jorgensen, Matthew J.;
- Justice, Jamie N.;
- Kritchevsky, Stephen B.;
- Register, Thomas C.;
- Shively, Carol A.
Publication type:
Correction Notice
Temporal emergence of age-associated changes in cognitive and physical function in vervets (Chlorocebus aethiops sabaeus).
Published in:
GeroScience, 2021, v. 43, n. 3, p. 1303, doi. 10.1007/s11357-021-00338-w
By:
- Frye, Brett M.;
- Valure, Payton M.;
- Craft, Suzanne;
- Baxter, Mark G.;
- Scott, Christie;
- Wise-Walden, Shanna;
- Bissinger, David W.;
- Register, Hannah M.;
- Copeland, Carson;
- Jorgensen, Matthew J.;
- Justice, Jamie N.;
- Kritchevsky, Stephen B.;
- Register, Thomas C.;
- Shively, Carol A.
Publication type:
Article
A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin.
Published in:
GeroScience, 2021, v. 43, n. 3, p. 1093, doi. 10.1007/s11357-020-00261-6
By:
- Justice, Jamie N.;
- Gubbi, Sriram;
- Kulkarni, Ameya S.;
- Bartley, Jenna M.;
- Kuchel, George A.;
- Barzilai, Nir
Publication type:
Article
Lipotoxicity, aging, and muscle contractility: does fiber type matter?
Published in:
GeroScience, 2019, v. 41, n. 3, p. 297, doi. 10.1007/s11357-019-00077-z
By:
- Carter, Christy S.;
- Justice, Jamie N.;
- Thompson, LaDora
Publication type:
Article
A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup.
Published in:
GeroScience, 2018, v. 40, n. 5/6, p. 419, doi. 10.1007/s11357-018-0042-y
By:
- Justice, Jamie N.;
- Ferrucci, Luigi;
- Newman, Anne B.;
- Aroda, Vanita R.;
- Bahnson, Judy L.;
- Divers, Jasmin;
- Espeland, Mark A.;
- Marcovina, Santica;
- Pollak, Michael N.;
- Kritchevsky, Stephen B.;
- Barzilai, Nir;
- Kuchel, George A.
Publication type:
Article
Relationships of depressive behavior and sertraline treatment with walking speed and activity in older female nonhuman primates.
Published in:
GeroScience, 2017, v. 39, n. 5/6, p. 585, doi. 10.1007/s11357-017-9999-1
By:
- Justice, Jamie;
- Silverstein-Metzler, Marnie;
- Uberseder, Beth;
- Appt, Susan;
- Clarkson, Thomas;
- Register, Thomas;
- Kritchevsky, Stephen;
- Shively, Carol
Publication type:
Article
Leveraging inter-individual transcriptional correlation structure to infer discrete signaling mechanisms across metabolic tissues.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.88863
By:
- Mingqi Zhou;
- Tamburini, Ian;
- Van, Cassandra;
- Molendijk, Jeffrey;
- Nguyen, Christy M.;
- Ivan Yao-Yi Chang;
- Johnson, Casey;
- Velez, Leandro M.;
- Youngseo Cheon;
- Reichelle Yeo;
- Bae, Hosung;
- Le, Johnny;
- Larson, Natalie;
- Pulido, Ron;
- Nascimento-Filho, Carlos H. V.;
- Cholsoon Jang;
- Marazzi, Ivan;
- Justice, Jamie;
- Pannunzio, Nicholas;
- Hevener, Andrea L.
Publication type:
Article
Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old mice (LB817).
Published in:
FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.lb817
By:
- Battson, Micah;
- Gioscia‐Ryan, Rachel;
- Johnson, Lawrence;
- Seals, Douglas;
- Justice, Jamie
Publication type:
Article
Effects of sodium nitrite supplementation on exercise capacity in middle‐aged and older healthy adults (LB689).
Published in:
FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.lb689
By:
- Bassett, Candace;
- Evans, Trent;
- Justice, Jamie;
- Brooks, Forrest;
- Chonchol, Michel;
- Giordano, Tony;
- Seals, Douglas;
- DeVan, Allison
Publication type:
Article
Muscle activity differs with load compliance during fatiguing contractions with the knee extensor muscles.
Published in:
Experimental Brain Research, 2010, v. 203, n. 2, p. 307, doi. 10.1007/s00221-010-2233-3
By:
- Rudroff, Thorsten;
- Justice, Jamie N.;
- Matthews, Stephen;
- Zuo, Rena;
- Enoka, Roger M.
Publication type:
Article
Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity.
Published in:
Journal of Physiology, 2016, v. 594, n. 8, p. 2001, doi. 10.1113/jphysiol.2014.282665
By:
- Seals, Douglas R.;
- Justice, Jamie N.;
- LaRocca, Thomas J.
Publication type:
Article
Metformin for Treatment of Acute COVID-19: Systematic Review of Clinical Trial Data Against SARS-CoV-2.
Published in:
Diabetes Care, 2023, v. 46, n. 7, p. 1432, doi. 10.2337/dc22-2539
By:
- Erickson, Spencer M.;
- Fenno, Sarah L.;
- Barzilai, Nir;
- Kuchel, George;
- Bartley, Jenna M.;
- Justice, Jamie Nicole;
- Buse, John B.;
- Bramante, Carolyn T.
Publication type:
Article
An Examination of Whether Diabetes Control and Treatments Are Associated With Change in Frailty Index Across 8 Years: An Ancillary Exploratory Study From the Action for Health in Diabetes (Look AHEAD) Trial.
Published in:
Diabetes Care, 2023, v. 46, n. 3, p. 519, doi. 10.2337/dc22-1728
By:
- Simpson, Felicia R.;
- Justice, Jamie N.;
- Pilla, Scott J.;
- Kritchevsky, Stephen B.;
- Boyko, Edward J.;
- Munshi, Medha N.;
- Ferris, Chloe K.;
- Espeland, Mark A.
Publication type:
Article
Associations between regional adipose tissue distribution and skeletal muscle bioenergetics in older men and women.
Published in:
Obesity (19307381), 2024, v. 32, n. 6, p. 1125, doi. 10.1002/oby.24008
By:
- Brennan, Andrea M.;
- Coen, Paul M.;
- Mau, Theresa;
- Hetherington‐Rauth, Megan;
- Toledo, Frederico G. S.;
- Kershaw, Erin E.;
- Cawthon, Peggy M.;
- Kramer, Philip A.;
- Ramos, Sofhia V.;
- Newman, Anne B.;
- Cummings, Steven R.;
- Forman, Daniel E.;
- Yeo, Reichelle X.;
- Distefano, Giovanna;
- Miljkovic, Iva;
- Justice, Jamie N.;
- Molina, Anthony J. A.;
- Jurczak, Michael J.;
- Sparks, Lauren M.;
- Kritchevsky, Stephen B.
Publication type:
Article
Adipose Tissue Quality in Aging: How Structural and Functional Aspects of Adipose Tissue Impact Skeletal Muscle Quality.
Published in:
Nutrients, 2019, v. 11, n. 11, p. 2553, doi. 10.3390/nu11112553
By:
- De Carvalho, Flavia G.;
- Justice, Jamie N.;
- Freitas, Ellen C. de;
- Kershaw, Erin E.;
- Sparks, Lauren M.
Publication type:
Article
Battery of behavioral tests in mice that models age-associated changes in human motor function.
Published in:
Age, 2014, v. 36, n. 2, p. 583, doi. 10.1007/s11357-013-9589-9
By:
- Justice, Jamie;
- Carter, Christy;
- Beck, Hannah;
- Gioscia-Ryan, Rachel;
- McQueen, Matthew;
- Enoka, Roger;
- Seals, Douglas
Publication type:
Article

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